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The map label for this gene is 15669529

Identifier: 15669529

GI number: 15669529

Start: 1286291

End: 1287352

Strand: Direct

Name: 15669529

Synonym: MJ1338

Alternate gene names: NA

Gene position: 1286291-1287352 (Clockwise)

Preceding gene: 15669528

Following gene: 15669530

Centisome position: 77.26

GC content: 37.48

Gene sequence:

>1062_bases
ATGCGTAATATAAGAAAAATCAAGGTTGATAACATGAAGGTATCCGTATATGGAGCGGGGAATCAAAATCTATACATAAA
TAAATTAAACCTTCCAGAAAAATTCGGTGGGGAGCCACCTTATGGCGGTTCAAGGATGGCTATTGAATTTGCTGAGGCAG
GGCATGATGTTGTTTTAGCTGAACCAAATAAAAACATAATGAGTGATGATTTATGGAAAAAGGTTGAAGATGCTGGGGTT
AAGGTTGTTAGTGATGATGTCGAAGCTGCAAAGCACGGGGAAATTCATGTTTTATTTACCCCTTTTGGTAAGGCAACATT
TAGAATAGCAAAGACAATTATTGAACATGTTCCTGAAAATGCTGTTATTTGTAACACCTGCACTGTTTCACCTGTAGTGT
TATACTACTCATTAGAACCAATATTAAGAACAAAAAGAAAGGATGTAGGAATTTCATCAATGCATCCAGCAGCTGTTCCT
GGAACTCCACAACACGGACATTATGTGATTGGTGGGAAAACCACTGATGGAAAAGAATTGGCTACTGAGGAACAGATAAA
AAAAGCTGTAGAGCTTGCCAAAAGTGCAGGAAAAGAGGCTTATGTTGTTCCTGCTGATGTTTCTTCAGTTGTTGCTGATA
TGGGGAGTTTAGTTACTGCAGTTGCTTTATCGGGAGTTCTGGACTACTATACAGTTGGAAGAAAGATTATAAATGCTCCT
AAGAAGATGATTGAACAGCAAGTTATCATGACCCTACAGACAATGGCTTCTCTTGTTGAAACATCAGGTATTGAAGGGAT
GGTAAAGGCATTAAATCCAGAGTTATTAATAAGGAGTGCTTCATCAATGAAGTTATTAGATAGACAGAAGGATTTAGATG
CTGCCTTAGAGATTCTTCAAAACTTAGATGAAACATTAAAGGCAGAAGTAGAAAAAGCAGAAATAAAACCAACAACACTT
GTAGCGGCTCAATCATTAGTTAAGGAGATAAAAACTTTAATAGGAGGGGCTGCTGCAGAGGGGGCAATAAAAAGAAGTGC
AAGAAAATTATTTGAGCATTAA

Upstream 100 bases:

>100_bases
GCTTTAGAGAACACATTAAAGTAGTTGAGGGCGGTGAATAGCATAATAATAAGAAAAATAAATAATAAAGTATTTATATA
ATAATCATCAGAAACTCTAA

Downstream 100 bases:

>100_bases
ACTTATAATATTTTATTTTTAGGGGAGATTCATGAAAAAAGATGAGGTTAAGGTTGTAGTTATTGGTTCAAGTGATGTTG
GAAAAACAACATTAATGGAA

Product: H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-like protein

Products: 5,10-methenyltetrahydromethanopterin; reduced coenzyme F420

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MRNIRKIKVDNMKVSVYGAGNQNLYINKLNLPEKFGGEPPYGGSRMAIEFAEAGHDVVLAEPNKNIMSDDLWKKVEDAGV
KVVSDDVEAAKHGEIHVLFTPFGKATFRIAKTIIEHVPENAVICNTCTVSPVVLYYSLEPILRTKRKDVGISSMHPAAVP
GTPQHGHYVIGGKTTDGKELATEEQIKKAVELAKSAGKEAYVVPADVSSVVADMGSLVTAVALSGVLDYYTVGRKIINAP
KKMIEQQVIMTLQTMASLVETSGIEGMVKALNPELLIRSASSMKLLDRQKDLDAALEILQNLDETLKAEVEKAEIKPTTL
VAAQSLVKEIKTLIGGAAAEGAIKRSARKLFEH

Sequences:

>Translated_353_residues
MRNIRKIKVDNMKVSVYGAGNQNLYINKLNLPEKFGGEPPYGGSRMAIEFAEAGHDVVLAEPNKNIMSDDLWKKVEDAGV
KVVSDDVEAAKHGEIHVLFTPFGKATFRIAKTIIEHVPENAVICNTCTVSPVVLYYSLEPILRTKRKDVGISSMHPAAVP
GTPQHGHYVIGGKTTDGKELATEEQIKKAVELAKSAGKEAYVVPADVSSVVADMGSLVTAVALSGVLDYYTVGRKIINAP
KKMIEQQVIMTLQTMASLVETSGIEGMVKALNPELLIRSASSMKLLDRQKDLDAALEILQNLDETLKAEVEKAEIKPTTL
VAAQSLVKEIKTLIGGAAAEGAIKRSARKLFEH
>Mature_353_residues
MRNIRKIKVDNMKVSVYGAGNQNLYINKLNLPEKFGGEPPYGGSRMAIEFAEAGHDVVLAEPNKNIMSDDLWKKVEDAGV
KVVSDDVEAAKHGEIHVLFTPFGKATFRIAKTIIEHVPENAVICNTCTVSPVVLYYSLEPILRTKRKDVGISSMHPAAVP
GTPQHGHYVIGGKTTDGKELATEEQIKKAVELAKSAGKEAYVVPADVSSVVADMGSLVTAVALSGVLDYYTVGRKIINAP
KKMIEQQVIMTLQTMASLVETSGIEGMVKALNPELLIRSASSMKLLDRQKDLDAALEILQNLDETLKAEVEKAEIKPTTL
VAAQSLVKEIKTLIGGAAAEGAIKRSARKLFEH

Specific function: Unknown

COG id: COG4007

COG function: function code R; Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HMD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HMDY_METJA (Q58734)

Other databases:

- EMBL:   L77117
- PIR:   A64467
- RefSeq:   NP_248340.1
- ProteinModelPortal:   Q58734
- SMR:   Q58734
- GeneID:   1452241
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1338
- NMPDR:   fig|243232.1.peg.1377
- TIGR:   MJ1338
- HOGENOM:   HBG541201
- OMA:   IKPTTLV
- ProtClustDB:   PRK12557
- BioCyc:   MJAN243232:MJ_1338-MONOMER
- GO:   GO:0005488
- GO:   GO:0015948
- InterPro:   IPR008927
- InterPro:   IPR010063
- InterPro:   IPR004889
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- TIGRFAMs:   TIGR01724

Pfam domain/function: PF03201 HMD; SSF48179 6DGDH_C_like

EC number: 1.5.99.9

Molecular weight: Translated: 38213; Mature: 38213

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNIRKIKVDNMKVSVYGAGNQNLYINKLNLPEKFGGEPPYGGSRMAIEFAEAGHDVVLA
CCCCEEEEECCEEEEEEECCCCEEEEEECCCCHHCCCCCCCCCCEEEEEEECCCCEEEEE
EPNKNIMSDDLWKKVEDAGVKVVSDDVEAAKHGEIHVLFTPFGKATFRIAKTIIEHVPEN
CCCCCCCHHHHHHHHHHCCCEEEECCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCC
AVICNTCTVSPVVLYYSLEPILRTKRKDVGISSMHPAAVPGTPQHGHYVIGGKTTDGKEL
CEEEECCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHH
ATEEQIKKAVELAKSAGKEAYVVPADVSSVVADMGSLVTAVALSGVLDYYTVGRKIINAP
HHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKMIEQQVIMTLQTMASLVETSGIEGMVKALNPELLIRSASSMKLLDRQKDLDAALEILQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHEEECCHHHHHHHHHCCHHHHHHHHH
NLDETLKAEVEKAEIKPTTLVAAQSLVKEIKTLIGGAAAEGAIKRSARKLFEH
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRNIRKIKVDNMKVSVYGAGNQNLYINKLNLPEKFGGEPPYGGSRMAIEFAEAGHDVVLA
CCCCEEEEECCEEEEEEECCCCEEEEEECCCCHHCCCCCCCCCCEEEEEEECCCCEEEEE
EPNKNIMSDDLWKKVEDAGVKVVSDDVEAAKHGEIHVLFTPFGKATFRIAKTIIEHVPEN
CCCCCCCHHHHHHHHHHCCCEEEECCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCC
AVICNTCTVSPVVLYYSLEPILRTKRKDVGISSMHPAAVPGTPQHGHYVIGGKTTDGKEL
CEEEECCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHH
ATEEQIKKAVELAKSAGKEAYVVPADVSSVVADMGSLVTAVALSGVLDYYTVGRKIINAP
HHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKMIEQQVIMTLQTMASLVETSGIEGMVKALNPELLIRSASSMKLLDRQKDLDAALEILQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHEEECCHHHHHHHHHCCHHHHHHHHH
NLDETLKAEVEKAEIKPTTLVAAQSLVKEIKTLIGGAAAEGAIKRSARKLFEH
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5,10-methylenetetrahydromethanopterin; coenzyme F420

Specific reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087