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The map label for this gene is hsdS [C]

Identifier: 15669403

GI number: 15669403

Start: 1160579

End: 1161856

Strand: Reverse

Name: hsdS [C]

Synonym: MJ1218

Alternate gene names: 15669403

Gene position: 1161856-1160579 (Counterclockwise)

Preceding gene: 15669404

Following gene: 15669402

Centisome position: 69.78

GC content: 27.62

Gene sequence:

>1278_bases
TTGGTGATAATTATGCAATTTTATAAAGAAGAGAATTTTAAAGAGATGCATGGGTTGAGAGTTCCAGAGGACTGGGAAGT
TGTAAGAATTGGAGATTTTATAAAATATATTAAAGGTAAAAAACCAGCTGTTATGGTAGATGAAGAACTTGAAGGTTATT
ATCCTTATTTATCAACTGAGTATTTAAGGGATGGAATAGCTTCAAAATTTGTAAAAATAACCAATAAGGAAATTATTGTA
AATGAGAATGATATACTGCTATTATGGGATGGTTCAAATGCAGGGGAGATATTTTTAGGTAAAAAAGGAATTCTTTCTTC
AACAATGGTAAAATTAGAACAGAAAAATAAAATTATGGACGATTTATATTTATTTTATTCCCTAAAGTTAAAAGAAAGTT
TTCTAAAAAGTCAAACAAAAGGAACTGGAATTCCACACGTAGATAAAAAAATATTTGAAAATATAAAAATCCCCCTCCCT
CCCTTAGAAGAACAGAAACAAATAGCAAAAATATTAAGTGACTTTGATAACCTAATAGGAACAATAAATAAGCAGATTGA
AGTATTAAATAAGGCAAAAAAGGGGATGATGAAAAAATTATTTACTAAAGGAGTTTTTGAGCATAAAAGTTTTAAAAAAT
CAGAGATTGGAGAGATTCCAGAGGATTGGGAGGTTGTTAAATTAAAGGAAGTAGTGGATATACAATCTGGAAAATATTTT
AAATATTCAGAATTTTGTGAAAATGGTGTAAAATGTTTGAAAATCGATAATGTAGGATTTGGGAAAATTTTTTGGGAAAC
AGTTTCTTTTCTTCCAGAAGATTATTTGAATAAGTATCCACAATTAGTTTTAAAATCTGGAGATATAGTATTGGCATTGA
ATAGACCAATAATAGGTGGAAAAATAAAAATTGGAATTTTAAAGGATATAGATGAGCCAGCTATACTCTATCAAAGAGTA
GGAAGATTTATTTTTAAAAGTGAAAAGATAGACAAACAGTTTTTGTTTTATTTGTTAATGAGTGAATATTTCAAAAAAGA
ACTTTCTAAATTGCTTATTGGGACTGACCAGCCTTATATAAGAACACCCGTCCTACTAAACATAAAAATCCCTCTTCCTC
ACTTAGAAGAACAAAAGGCAATGGCTGAAAGATTAAAAAGTATAGACAACCTAATAGAAATAAAAAGAAAAGAAAAAGAA
CAAATAGAAAAAGCAAAAAAGAAAATAATGAATCTACTACTAACTGGAAAAATAAGAGTAAAAAATTTAAATTTTTAA

Upstream 100 bases:

>100_bases
TTTGTTATTCTATTCGATTATTGCTTTTATAGTTATGTCCATATTGATTTTAATTTTTGGGAATAATCGTGGAGGATATT
ATTACTAAATACTATTTTTT

Downstream 100 bases:

>100_bases
AATAAAATTTTTATTGTTAATAAAATTTTGCTGGTGAAATTATGAAAACTCTCTCTGAAATAAAAGAAATCCTAAGAAAA
CATAAAAAAATACTCAAAGA

Product: type I restriction-modification enzyme 1 subunit S

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MVIIMQFYKEENFKEMHGLRVPEDWEVVRIGDFIKYIKGKKPAVMVDEELEGYYPYLSTEYLRDGIASKFVKITNKEIIV
NENDILLLWDGSNAGEIFLGKKGILSSTMVKLEQKNKIMDDLYLFYSLKLKESFLKSQTKGTGIPHVDKKIFENIKIPLP
PLEEQKQIAKILSDFDNLIGTINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEVVKLKEVVDIQSGKYF
KYSEFCENGVKCLKIDNVGFGKIFWETVSFLPEDYLNKYPQLVLKSGDIVLALNRPIIGGKIKIGILKDIDEPAILYQRV
GRFIFKSEKIDKQFLFYLLMSEYFKKELSKLLIGTDQPYIRTPVLLNIKIPLPHLEEQKAMAERLKSIDNLIEIKRKEKE
QIEKAKKKIMNLLLTGKIRVKNLNF

Sequences:

>Translated_425_residues
MVIIMQFYKEENFKEMHGLRVPEDWEVVRIGDFIKYIKGKKPAVMVDEELEGYYPYLSTEYLRDGIASKFVKITNKEIIV
NENDILLLWDGSNAGEIFLGKKGILSSTMVKLEQKNKIMDDLYLFYSLKLKESFLKSQTKGTGIPHVDKKIFENIKIPLP
PLEEQKQIAKILSDFDNLIGTINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEVVKLKEVVDIQSGKYF
KYSEFCENGVKCLKIDNVGFGKIFWETVSFLPEDYLNKYPQLVLKSGDIVLALNRPIIGGKIKIGILKDIDEPAILYQRV
GRFIFKSEKIDKQFLFYLLMSEYFKKELSKLLIGTDQPYIRTPVLLNIKIPLPHLEEQKAMAERLKSIDNLIEIKRKEKE
QIEKAKKKIMNLLLTGKIRVKNLNF
>Mature_425_residues
MVIIMQFYKEENFKEMHGLRVPEDWEVVRIGDFIKYIKGKKPAVMVDEELEGYYPYLSTEYLRDGIASKFVKITNKEIIV
NENDILLLWDGSNAGEIFLGKKGILSSTMVKLEQKNKIMDDLYLFYSLKLKESFLKSQTKGTGIPHVDKKIFENIKIPLP
PLEEQKQIAKILSDFDNLIGTINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEVVKLKEVVDIQSGKYF
KYSEFCENGVKCLKIDNVGFGKIFWETVSFLPEDYLNKYPQLVLKSGDIVLALNRPIIGGKIKIGILKDIDEPAILYQRV
GRFIFKSEKIDKQFLFYLLMSEYFKKELSKLLIGTDQPYIRTPVLLNIKIPLPHLEEQKAMAERLKSIDNLIEIKRKEKE
QIEKAKKKIMNLLLTGKIRVKNLNF

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1218_METJA (Q58615)

Other databases:

- EMBL:   L77117
- PIR:   A64452
- RefSeq:   NP_248213.1
- ProteinModelPortal:   Q58615
- REBASE:   3904
- GeneID:   1452114
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1218
- NMPDR:   fig|243232.1.peg.1250
- TIGR:   MJ1218
- HOGENOM:   HBG538952
- OMA:   CLSSIDD
- BioCyc:   MJAN243232:MJ_1218-MONOMER
- InterPro:   IPR000055

Pfam domain/function: PF01420 Methylase_S

EC number: NA

Molecular weight: Translated: 49411; Mature: 49411

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIIMQFYKEENFKEMHGLRVPEDWEVVRIGDFIKYIKGKKPAVMVDEELEGYYPYLSTE
CEEEEEECCCCCHHHHHCCCCCCCCCEEEHHHHHHHHCCCCCEEEECHHCCCCCCCCCHH
YLRDGIASKFVKITNKEIIVNENDILLLWDGSNAGEIFLGKKGILSSTMVKLEQKNKIMD
HHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
DLYLFYSLKLKESFLKSQTKGTGIPHVDKKIFENIKIPLPPLEEQKQIAKILSDFDNLIG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEVVKLKEVVDIQSGKYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHEEHHHHHHCCCCCCE
KYSEFCENGVKCLKIDNVGFGKIFWETVSFLPEDYLNKYPQLVLKSGDIVLALNRPIIGG
EHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHEEECCCEEEEECCCEECC
KIKIGILKDIDEPAILYQRVGRFIFKSEKIDKQFLFYLLMSEYFKKELSKLLIGTDQPYI
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
RTPVLLNIKIPLPHLEEQKAMAERLKSIDNLIEIKRKEKEQIEKAKKKIMNLLLTGKIRV
ECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
KNLNF
ECCCC
>Mature Secondary Structure
MVIIMQFYKEENFKEMHGLRVPEDWEVVRIGDFIKYIKGKKPAVMVDEELEGYYPYLSTE
CEEEEEECCCCCHHHHHCCCCCCCCCEEEHHHHHHHHCCCCCEEEECHHCCCCCCCCCHH
YLRDGIASKFVKITNKEIIVNENDILLLWDGSNAGEIFLGKKGILSSTMVKLEQKNKIMD
HHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
DLYLFYSLKLKESFLKSQTKGTGIPHVDKKIFENIKIPLPPLEEQKQIAKILSDFDNLIG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEVVKLKEVVDIQSGKYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHEEHHHHHHCCCCCCE
KYSEFCENGVKCLKIDNVGFGKIFWETVSFLPEDYLNKYPQLVLKSGDIVLALNRPIIGG
EHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHEEECCCEEEEECCCEECC
KIKIGILKDIDEPAILYQRVGRFIFKSEKIDKQFLFYLLMSEYFKKELSKLLIGTDQPYI
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
RTPVLLNIKIPLPHLEEQKAMAERLKSIDNLIEIKRKEKEQIEKAKKKIMNLLLTGKIRV
ECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
KNLNF
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087