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The map label for this gene is moaC

Identifier: 15669322

GI number: 15669322

Start: 1075574

End: 1076032

Strand: Reverse

Name: moaC

Synonym: MJ1135

Alternate gene names: 15669322

Gene position: 1076032-1075574 (Counterclockwise)

Preceding gene: 15669324

Following gene: 15669321

Centisome position: 64.63

GC content: 31.81

Gene sequence:

>459_bases
ATGCTAACTCATGTTGATGATAAAGGCGTTAAGATGGTTGATATTTCTAAAAAAGAAGATGTTGAGAGAATATGTGTTGC
TGAAGGATACATAAAATTAAAACCAGAAACAATTAAATTAATAAAAGAACAAAAAATTAAAAAGGGAAATGTCTTAACAA
CTGCACAAATAGCTGGAATCTTGGCAGTTAAAAAAACTTATGAGCTAATTCCAATGTGCCATCCTCTACCAATAACTTCA
GTTAATGTTGATTTTGAGGTATTTGAAGATAAGATAAAGGCAATCTGCTCAGTAAAAACTACTTATAAGACAGGAATTGA
GATGGAAGCTTTAACTGGTGTCTCTATAGCTTTATTAACAATTTGGGATATGGTTAAATCTGCTGAAAAGGATGAGGATG
GGCAGTACAAAACTGCTGAGATTTTTGGGATTAGGGTTGTTGAAAAGATAAAGAAATAG

Upstream 100 bases:

>100_bases
ACATTTTATTCCTGCGAAAGTTCTATATAGTTTATTCGGCAATGATTATAATGTTATTGTATAATTGTAGTATTTGGTTT
AATAAAGTAGTGGTGATTAA

Downstream 100 bases:

>100_bases
TTTATTTAGGGGATTGCAATGATTGATTCTAACTTTGACATTGTTCTTTGGGTTAGGATGATTAAAGAAGGGATTGAAAA
GAAAAATCTAAATCCTTGGG

Product: putative molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MLTHVDDKGVKMVDISKKEDVERICVAEGYIKLKPETIKLIKEQKIKKGNVLTTAQIAGILAVKKTYELIPMCHPLPITS
VNVDFEVFEDKIKAICSVKTTYKTGIEMEALTGVSIALLTIWDMVKSAEKDEDGQYKTAEIFGIRVVEKIKK

Sequences:

>Translated_152_residues
MLTHVDDKGVKMVDISKKEDVERICVAEGYIKLKPETIKLIKEQKIKKGNVLTTAQIAGILAVKKTYELIPMCHPLPITS
VNVDFEVFEDKIKAICSVKTTYKTGIEMEALTGVSIALLTIWDMVKSAEKDEDGQYKTAEIFGIRVVEKIKK
>Mature_152_residues
MLTHVDDKGVKMVDISKKEDVERICVAEGYIKLKPETIKLIKEQKIKKGNVLTTAQIAGILAVKKTYELIPMCHPLPITS
VNVDFEVFEDKIKAICSVKTTYKTGIEMEALTGVSIALLTIWDMVKSAEKDEDGQYKTAEIFGIRVVEKIKK

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=135, Percent_Identity=42.962962962963, Blast_Score=115, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32566331, Length=130, Percent_Identity=45.3846153846154, Blast_Score=108, Evalue=8e-25,
Organism=Drosophila melanogaster, GI28574490, Length=133, Percent_Identity=42.1052631578947, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28574492, Length=122, Percent_Identity=40.9836065573771, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_METJA (Q58535)

Other databases:

- EMBL:   L77117
- PIR:   F64441
- RefSeq:   NP_248127.1
- ProteinModelPortal:   Q58535
- SMR:   Q58535
- GeneID:   1452031
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1135
- NMPDR:   fig|243232.1.peg.1164
- TIGR:   MJ1135
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK12343
- BioCyc:   MJAN243232:MJ_1135-MONOMER
- HAMAP:   MF_01224_A
- InterPro:   IPR023045
- InterPro:   IPR023047
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17043; Mature: 17043

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: ACT_SITE 123-123

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTHVDDKGVKMVDISKKEDVERICVAEGYIKLKPETIKLIKEQKIKKGNVLTTAQIAGI
CCCCCCCCCEEEEECCCHHHHHHHHHHCCEEEECHHHHHHHHHHHCCCCCEEEHHHHHHH
LAVKKTYELIPMCHPLPITSVNVDFEVFEDKIKAICSVKTTYKTGIEMEALTGVSIALLT
HHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCHHHHHHH
IWDMVKSAEKDEDGQYKTAEIFGIRVVEKIKK
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTHVDDKGVKMVDISKKEDVERICVAEGYIKLKPETIKLIKEQKIKKGNVLTTAQIAGI
CCCCCCCCCEEEEECCCHHHHHHHHHHCCEEEECHHHHHHHHHHHCCCCCEEEHHHHHHH
LAVKKTYELIPMCHPLPITSVNVDFEVFEDKIKAICSVKTTYKTGIEMEALTGVSIALLT
HHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCHHHHHHH
IWDMVKSAEKDEDGQYKTAEIFGIRVVEKIKK
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087