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The map label for this gene is cobY

Identifier: 15669304

GI number: 15669304

Start: 1058447

End: 1059037

Strand: Direct

Name: cobY

Synonym: MJ1117

Alternate gene names: 15669304

Gene position: 1058447-1059037 (Clockwise)

Preceding gene: 15669297

Following gene: 15669305

Centisome position: 63.57

GC content: 29.95

Gene sequence:

>591_bases
ATGGATGCTCTAATTATGGCTGGTGGTAAAGGAACAAGAATGGGTGGAGTTGAAAAGCCGTTGATTAAGCTTTGTGGTAG
ATGTCTTATAGATTATGTTGTCTCTCCCTTATTAAAATCAAAGGTAAATAATATATTTATCGCTACCTCTCCAAATACAC
CAAAGACAAAGGAATATATAAATTCAGCATATAAAGATTACAAAAATATTGTAGTTATAGACACATCTGGTAAAGGTTAT
ATAGAAGATTTAAATGAATGTATTGGATATTTCTCAGAACCATTCTTAGTTGTTAGCTCTGACTTAATTAACTTAAAATC
GAAAATTATTAATAGTATAGTTGATTATTTTTATTGTATTAAAGCTAAGACTCCAGATGTTGAAGCATTAGCTGTTATGA
TTCCAAAAGAAAAATATCCAAACCCCTCAATTGATTTCAACGGCTTAGTTCCTGCAGGGATAAATGTTGTATCCCCAAAG
CATGGATATCAAAAAGAAGAAATTATGGTTATTGATGAGCTGATATTCAATATAAATACTAAAGATGATTTAAAACTTGC
TGAAATGCTTTTGAAAAAAGATGGGTTATAA

Upstream 100 bases:

>100_bases
CACAACTTAACATTTTATGCTAAATATTTGCAAAATTTTAATTTAAATATCTTAATAAAGATTAAATCAATTTATTATAA
ATAACCTTAGAGGTTTTAAA

Downstream 100 bases:

>100_bases
ATATAAAAATCTAATGGGGATAAAATGGAAAAAATGCCAGCTAAGTTATTGTTTGAGAGAAGTATAATAGGAAATAAGGG
TAGCGTAATAGGAAAAGTTA

Product: hypothetical protein

Products: NA

Alternate protein names: AdoCbi-P guanylyltransferase

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MDALIMAGGKGTRMGGVEKPLIKLCGRCLIDYVVSPLLKSKVNNIFIATSPNTPKTKEYINSAYKDYKNIVVIDTSGKGY
IEDLNECIGYFSEPFLVVSSDLINLKSKIINSIVDYFYCIKAKTPDVEALAVMIPKEKYPNPSIDFNGLVPAGINVVSPK
HGYQKEEIMVIDELIFNINTKDDLKLAEMLLKKDGL

Sequences:

>Translated_196_residues
MDALIMAGGKGTRMGGVEKPLIKLCGRCLIDYVVSPLLKSKVNNIFIATSPNTPKTKEYINSAYKDYKNIVVIDTSGKGY
IEDLNECIGYFSEPFLVVSSDLINLKSKIINSIVDYFYCIKAKTPDVEALAVMIPKEKYPNPSIDFNGLVPAGINVVSPK
HGYQKEEIMVIDELIFNINTKDDLKLAEMLLKKDGL
>Mature_196_residues
MDALIMAGGKGTRMGGVEKPLIKLCGRCLIDYVVSPLLKSKVNNIFIATSPNTPKTKEYINSAYKDYKNIVVIDTSGKGY
IEDLNECIGYFSEPFLVVSSDLINLKSKIINSIVDYFYCIKAKTPDVEALAVMIPKEKYPNPSIDFNGLVPAGINVVSPK
HGYQKEEIMVIDELIFNINTKDDLKLAEMLLKKDGL

Specific function: Guanylyltransferase that catalyzes the synthesis of adenosylcobinamide-GDP (AdoCbi-GDP) from adenosylcobinamide- phosphate (AdoCbi-P) and GTP. Is involved in adenosylcobalamin biosynthesis. Binds one GTP per dimer. Can not use other NTPs or GDP. Does not

COG id: COG2266

COG function: function code H; GTP:adenosylcobinamide-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBY_METJA (Q58517)

Other databases:

- EMBL:   L77117
- PIR:   D64439
- RefSeq:   NP_248109.1
- ProteinModelPortal:   Q58517
- GeneID:   1452013
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1117
- NMPDR:   fig|243232.1.peg.1146
- TIGR:   MJ1117
- HOGENOM:   HBG645668
- OMA:   IVNVNTL
- ProtClustDB:   CLSK796738
- BioCyc:   MJAN243232:MJ_1117-MONOMER
- InterPro:   IPR005245
- InterPro:   IPR005835
- TIGRFAMs:   TIGR00454

Pfam domain/function: PF00483 NTP_transferase

EC number: =2.7.7.62

Molecular weight: Translated: 21746; Mature: 21746

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALIMAGGKGTRMGGVEKPLIKLCGRCLIDYVVSPLLKSKVNNIFIATSPNTPKTKEYI
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHH
NSAYKDYKNIVVIDTSGKGYIEDLNECIGYFSEPFLVVSSDLINLKSKIINSIVDYFYCI
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
KAKTPDVEALAVMIPKEKYPNPSIDFNGLVPAGINVVSPKHGYQKEEIMVIDELIFNINT
CCCCCCHHEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCC
KDDLKLAEMLLKKDGL
CCHHHHHHHHHHHCCC
>Mature Secondary Structure
MDALIMAGGKGTRMGGVEKPLIKLCGRCLIDYVVSPLLKSKVNNIFIATSPNTPKTKEYI
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHH
NSAYKDYKNIVVIDTSGKGYIEDLNECIGYFSEPFLVVSSDLINLKSKIINSIVDYFYCI
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
KAKTPDVEALAVMIPKEKYPNPSIDFNGLVPAGINVVSPKHGYQKEEIMVIDELIFNINT
CCCCCCHHEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCC
KDDLKLAEMLLKKDGL
CCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087