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The map label for this gene is pfdA1

Identifier: 15669142

GI number: 15669142

Start: 883878

End: 884306

Strand: Reverse

Name: pfdA1

Synonym: MJ0952

Alternate gene names: 15669142

Gene position: 884306-883878 (Counterclockwise)

Preceding gene: 15669144

Following gene: 15669141

Centisome position: 53.11

GC content: 29.37

Gene sequence:

>429_bases
GTGGAAAATATGGCTGAAGATTTAAGACAGAAAGCAATGGCCTTAGAAATATACAACCAACAATTACAAATGATTCAAAG
TGAAATTACTTCAATAAGAGCGTTAAAATCTGAAATAATGAATTCAATTAAAACAATTGAAAATATAAAGGCAGATGAAG
AGACATTAATCCCAGTAGGTCCTGGAGTGTTTTTAAAGGCAAAAATTGTTGATGATAAGGCATTAATTGGAGTAAAGTCA
GATATTTATGTTGAAAAATCATTTAATGAAGTTATTGAGGATTTAAAAAAGTCAGTTGAAGATTTAGATAAAGCTGAAAA
AGAAGGCATGAAGAAAGCTGAGGAATTAGCTAAAGCAATAACTGCATTAAGAAAAGAATTACAAACAGAGATACAAAAAG
CTCAACAAGCTCAAGATAAGAAACAATAA

Upstream 100 bases:

>100_bases
TCGCAGGAATAAATGTTTTATTGCATATTGACACTTTTGAGTGTCTAAATTCCAGTAAGAAGATAAGCTGCGAAAGTCCT
ATCTACATAATGCTTATGGG

Downstream 100 bases:

>100_bases
AAATGTAAAATTAAAATTTTTATCCTTTTTTATCTTATTTTTTGTACTCAGAATGCTTGATTAAACTAAAACAGTAATTC
CTATATTTAAACTAACAAAT

Product: prefoldin subunit alpha

Products: NA

Alternate protein names: GimC subunit alpha 1

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MENMAEDLRQKAMALEIYNQQLQMIQSEITSIRALKSEIMNSIKTIENIKADEETLIPVGPGVFLKAKIVDDKALIGVKS
DIYVEKSFNEVIEDLKKSVEDLDKAEKEGMKKAEELAKAITALRKELQTEIQKAQQAQDKKQ

Sequences:

>Translated_142_residues
MENMAEDLRQKAMALEIYNQQLQMIQSEITSIRALKSEIMNSIKTIENIKADEETLIPVGPGVFLKAKIVDDKALIGVKS
DIYVEKSFNEVIEDLKKSVEDLDKAEKEGMKKAEELAKAITALRKELQTEIQKAQQAQDKKQ
>Mature_142_residues
MENMAEDLRQKAMALEIYNQQLQMIQSEITSIRALKSEIMNSIKTIENIKADEETLIPVGPGVFLKAKIVDDKALIGVKS
DIYVEKSFNEVIEDLKKSVEDLDKAEKEGMKKAEELAKAITALRKELQTEIQKAQQAQDKKQ

Specific function: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding

COG id: COG1730

COG function: function code O; Predicted prefoldin, molecular chaperone implicated in de novo protein folding

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prefoldin subunit alpha family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PFDA1_METJA (Q58362)

Other databases:

- EMBL:   L77117
- PIR:   H64418
- RefSeq:   NP_247947.1
- ProteinModelPortal:   Q58362
- SMR:   Q58362
- GeneID:   1451850
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0952
- NMPDR:   fig|243232.1.peg.984
- TIGR:   MJ0952
- HOGENOM:   HBG541032
- OMA:   EELQNQF
- ProtClustDB:   PRK14011
- BioCyc:   MJAN243232:MJ_0952-MONOMER
- HAMAP:   MF_00308
- InterPro:   IPR011599
- InterPro:   IPR009053
- InterPro:   IPR004127
- TIGRFAMs:   TIGR00293

Pfam domain/function: PF02996 Prefoldin; SSF46579 Prefoldin

EC number: NA

Molecular weight: Translated: 16080; Mature: 16080

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENMAEDLRQKAMALEIYNQQLQMIQSEITSIRALKSEIMNSIKTIENIKADEETLIPVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PGVFLKAKIVDDKALIGVKSDIYVEKSFNEVIEDLKKSVEDLDKAEKEGMKKAEELAKAI
CCCEEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALRKELQTEIQKAQQAQDKKQ
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MENMAEDLRQKAMALEIYNQQLQMIQSEITSIRALKSEIMNSIKTIENIKADEETLIPVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PGVFLKAKIVDDKALIGVKSDIYVEKSFNEVIEDLKKSVEDLDKAEKEGMKKAEELAKAI
CCCEEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALRKELQTEIQKAQQAQDKKQ
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087