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The map label for this gene is cbiL

Identifier: 15668952

GI number: 15668952

Start: 691739

End: 692431

Strand: Direct

Name: cbiL

Synonym: MJ0771

Alternate gene names: 15668952

Gene position: 691739-692431 (Clockwise)

Preceding gene: 15668949

Following gene: 15668953

Centisome position: 41.55

GC content: 31.17

Gene sequence:

>693_bases
GTGAATAAATTGGTAAAGAAGGTTTATGGTGTTGGTGTAGGTGTTGGAGACAAAAAGCTATTAACATTAAAGGCATTAGA
GGTTTTAAAAAAAGTAGATAAAATCTTTGTCCCAGTATCTAAAAAGGGGAAGAAATCTATTGCCTATGAAATTATAAAGG
ATTATGTTGATGGGAAGAATATTGAAGAACTTTTATTCCCCATGATTAAAGATAAAGAGAGGCTAAAAAAATACTGGGAA
AATGCTTTAGAGAAGGTTTTAAAAGAAGATGGAGAAGTAGCTATAATAACCATTGGAGACCCTACATTGTATAGCACATT
CTCCTATGTCTGGAAACTTTTAAAAGAAAGAGGGGTTGAGGTAGAGATAGTTAATGGCATTTCATCAATATTTGCCTCTG
CAGCTGCTTTAAATATTCCATTAGTTGAAGGAGATGAAAAACTCTGCATTTTACCTCAAGGAAAGGATTTGGAAAAATAT
ATTGATGAATTCGACACTATAATTATTATGAAGACAAAGAATTTAAATGAGAAGCTATCAGTTATAAAAAATAGAGATGA
TTATATAATTGGGTTGGTAAAGAGGGCAACTTTTGAAGATGAAAAAGTAGTAATTGGTAAGTTAGACGAAATCAACTTTG
ATGAATTTAATGACTATCTCTCCTTAGCTATAATAAAGAGGTTTAAGAGATGA

Upstream 100 bases:

>100_bases
CCATATCATCATGTCACCAAAAATTTATTGTCAATTTAGCTAAATTTATATAGTAAGTTATCTAAAAAAGTTTTTAATTG
TAATTTTATAAAATCGTAAG

Downstream 100 bases:

>100_bases
AAATAATAAAAGCAGTTCCAGAAGAGTTTTTAAATGGATTGTATTTAATTCCAACTGACAGAGGGAATTTATTGGAATTA
GATGAAAACGGAAATTTTGA

Product: cobalamin biosynthesis precorrin-2 methyltransferase CbiL

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNKLVKKVYGVGVGVGDKKLLTLKALEVLKKVDKIFVPVSKKGKKSIAYEIIKDYVDGKNIEELLFPMIKDKERLKKYWE
NALEKVLKEDGEVAIITIGDPTLYSTFSYVWKLLKERGVEVEIVNGISSIFASAAALNIPLVEGDEKLCILPQGKDLEKY
IDEFDTIIIMKTKNLNEKLSVIKNRDDYIIGLVKRATFEDEKVVIGKLDEINFDEFNDYLSLAIIKRFKR

Sequences:

>Translated_230_residues
MNKLVKKVYGVGVGVGDKKLLTLKALEVLKKVDKIFVPVSKKGKKSIAYEIIKDYVDGKNIEELLFPMIKDKERLKKYWE
NALEKVLKEDGEVAIITIGDPTLYSTFSYVWKLLKERGVEVEIVNGISSIFASAAALNIPLVEGDEKLCILPQGKDLEKY
IDEFDTIIIMKTKNLNEKLSVIKNRDDYIIGLVKRATFEDEKVVIGKLDEINFDEFNDYLSLAIIKRFKR
>Mature_230_residues
MNKLVKKVYGVGVGVGDKKLLTLKALEVLKKVDKIFVPVSKKGKKSIAYEIIKDYVDGKNIEELLFPMIKDKERLKKYWE
NALEKVLKEDGEVAIITIGDPTLYSTFSYVWKLLKERGVEVEIVNGISSIFASAAALNIPLVEGDEKLCILPQGKDLEKY
IDEFDTIIIMKTKNLNEKLSVIKNRDDYIIGLVKRATFEDEKVVIGKLDEINFDEFNDYLSLAIIKRFKR

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBIL_METJA (Q58181)

Other databases:

- EMBL:   L77117
- PIR:   C64396
- RefSeq:   NP_247756.1
- ProteinModelPortal:   Q58181
- SMR:   Q58181
- GeneID:   1451648
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0771
- NMPDR:   fig|243232.1.peg.793
- TIGR:   MJ0771
- HOGENOM:   HBG724388
- OMA:   LNIPLVE
- ProtClustDB:   CLSK876323
- BioCyc:   MJAN243232:MJ_0771-MONOMER
- BRENDA:   2.1.1.151
- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043
- Gene3D:   G3DSA:3.40.1010.10
- PIRSF:   PIRSF036427
- TIGRFAMs:   TIGR01467

Pfam domain/function: PF00590 TP_methylase; SSF53790 Cor/por_Metransf

EC number: =2.1.1.151

Molecular weight: Translated: 26267; Mature: 26267

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLVKKVYGVGVGVGDKKLLTLKALEVLKKVDKIFVPVSKKGKKSIAYEIIKDYVDGKN
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
IEELLFPMIKDKERLKKYWENALEKVLKEDGEVAIITIGDPTLYSTFSYVWKLLKERGVE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCE
VEIVNGISSIFASAAALNIPLVEGDEKLCILPQGKDLEKYIDEFDTIIIMKTKNLNEKLS
EEEHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCHHHHHHHHCEEEEEEECCCCHHHH
VIKNRDDYIIGLVKRATFEDEKVVIGKLDEINFDEFNDYLSLAIIKRFKR
HHCCCCCEEEEEEHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKLVKKVYGVGVGVGDKKLLTLKALEVLKKVDKIFVPVSKKGKKSIAYEIIKDYVDGKN
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
IEELLFPMIKDKERLKKYWENALEKVLKEDGEVAIITIGDPTLYSTFSYVWKLLKERGVE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCE
VEIVNGISSIFASAAALNIPLVEGDEKLCILPQGKDLEKYIDEFDTIIIMKTKNLNEKLS
EEEHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCHHHHHHHHCEEEEEEECCCCHHHH
VIKNRDDYIIGLVKRATFEDEKVVIGKLDEINFDEFNDYLSLAIIKRFKR
HHCCCCCEEEEEEHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087