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The map label for this gene is ahpC [C]

Identifier: 15668917

GI number: 15668917

Start: 666904

End: 667572

Strand: Reverse

Name: ahpC [C]

Synonym: MJ0736

Alternate gene names: 15668917

Gene position: 667572-666904 (Counterclockwise)

Preceding gene: 15668918

Following gene: 15668916

Centisome position: 40.1

GC content: 36.32

Gene sequence:

>669_bases
ATGTGTGAAGGAAAAATGCCAGTTATTGGTGAGAAATTCCCAGAAGTAGAGGTTAAAACAACCCATGGAGCTATTAAATT
ACCAGATTATTATGTAGAGAAAGGAAAGTGGTTTGTTTTATTCAGCCATCCTGCTGACTTTACTCCGGTTTGCACAACAG
AGTTCGTAGGATTTCAAAAGAGATACGATGAATTTAGGAAACTAAATACTGAGTTGATTGGATTAAGTATAGATCAAGTT
TTTAGCCACTTAAAATGGGTCGAGTGGATAAAAGAAAAATTGAATGTAGAAATTGAGTTTCCAATTATAGCGGATGATAG
AGGAGAGTTAGCAGAGAAATTGGGAATGATAAGCCCATACAAAGGAAACAATACAGTTAGGGCTGTGTTTGTTGTAGATA
ATAAAGGGATAATTAGGGCTATCATCTACTATCCGCAAGAAGTTGGTAGAAACTTGGATGAGATCGTTAGATTAGTTAAA
GCTCTCCAAGTTTCAGATGAAAAAGGAGTGGCTATGCCAGCGAATTGGCCTGAAAATGATTTAATTGGAGATAAAGTTAT
TATACCTCCTGCATCATCAGTGGAGGAGATAAAGCAAAGAAAAGAGGCATGTGAGAAAGGGGAGATTGAGTGCTTAGATT
GGTGGTTCTGTTATAAAAAGTTAGATTAA

Upstream 100 bases:

>100_bases
TCCAAATCAAGAAAGCAAAATGTAAAAGAAAAGCAAATATAAAATAAAAACCAATAAAACTTAAATAAACAAAAGATAAA
ATAAAAAGGAGGGGAGAAAA

Downstream 100 bases:

>100_bases
AACTTTCAATGAAATTACTATATATTTAACACATATTATAAATTTCTAAATCTTTTTAATTAATTGTAATTGTTTTTTGA
GGTGGAAATATGGTAGAATT

Product: peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MCEGKMPVIGEKFPEVEVKTTHGAIKLPDYYVEKGKWFVLFSHPADFTPVCTTEFVGFQKRYDEFRKLNTELIGLSIDQV
FSHLKWVEWIKEKLNVEIEFPIIADDRGELAEKLGMISPYKGNNTVRAVFVVDNKGIIRAIIYYPQEVGRNLDEIVRLVK
ALQVSDEKGVAMPANWPENDLIGDKVIIPPASSVEEIKQRKEACEKGEIECLDWWFCYKKLD

Sequences:

>Translated_222_residues
MCEGKMPVIGEKFPEVEVKTTHGAIKLPDYYVEKGKWFVLFSHPADFTPVCTTEFVGFQKRYDEFRKLNTELIGLSIDQV
FSHLKWVEWIKEKLNVEIEFPIIADDRGELAEKLGMISPYKGNNTVRAVFVVDNKGIIRAIIYYPQEVGRNLDEIVRLVK
ALQVSDEKGVAMPANWPENDLIGDKVIIPPASSVEEIKQRKEACEKGEIECLDWWFCYKKLD
>Mature_222_residues
MCEGKMPVIGEKFPEVEVKTTHGAIKLPDYYVEKGKWFVLFSHPADFTPVCTTEFVGFQKRYDEFRKLNTELIGLSIDQV
FSHLKWVEWIKEKLNVEIEFPIIADDRGELAEKLGMISPYKGNNTVRAVFVVDNKGIIRAIIYYPQEVGRNLDEIVRLVK
ALQVSDEKGVAMPANWPENDLIGDKVIIPPASSVEEIKQRKEACEKGEIECLDWWFCYKKLD

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=201, Percent_Identity=41.2935323383085, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI32189392, Length=160, Percent_Identity=40.625, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI4505591, Length=160, Percent_Identity=40.625, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI32455266, Length=160, Percent_Identity=40.625, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI32455264, Length=160, Percent_Identity=40.625, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI5453549, Length=173, Percent_Identity=37.5722543352601, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI5802974, Length=168, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI32483377, Length=168, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI33188454, Length=64, Percent_Identity=51.5625, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1786822, Length=165, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25153706, Length=186, Percent_Identity=37.0967741935484, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17554494, Length=147, Percent_Identity=37.4149659863946, Blast_Score=113, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI32565831, Length=160, Percent_Identity=36.875, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193204376, Length=160, Percent_Identity=36.875, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319407, Length=200, Percent_Identity=45.5, Blast_Score=150, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6323613, Length=174, Percent_Identity=33.9080459770115, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320661, Length=144, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24581278, Length=202, Percent_Identity=42.5742574257426, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17975518, Length=200, Percent_Identity=39.5, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24652434, Length=197, Percent_Identity=40.1015228426396, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24652436, Length=200, Percent_Identity=39, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI17157991, Length=153, Percent_Identity=39.8692810457516, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24641739, Length=153, Percent_Identity=39.8692810457516, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17738015, Length=163, Percent_Identity=36.8098159509202, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24656348, Length=150, Percent_Identity=36.6666666666667, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17864676, Length=150, Percent_Identity=36.6666666666667, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21357347, Length=164, Percent_Identity=35.3658536585366, Blast_Score=103, Evalue=8e-23,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 25559; Mature: 25559

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCEGKMPVIGEKFPEVEVKTTHGAIKLPDYYVEKGKWFVLFSHPADFTPVCTTEFVGFQK
CCCCCCCCCCCCCCCEEEEECCCEEECCHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHH
RYDEFRKLNTELIGLSIDQVFSHLKWVEWIKEKLNVEIEFPIIADDRGELAEKLGMISPY
HHHHHHHHCHHHEEEEHHHHHHHHHHHHHHHHHCCEEEEEEEEECCHHHHHHHHCCCCCC
KGNNTVRAVFVVDNKGIIRAIIYYPQEVGRNLDEIVRLVKALQVSDEKGVAMPANWPEND
CCCCEEEEEEEECCCCEEEHEEECCHHHCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCC
LIGDKVIIPPASSVEEIKQRKEACEKGEIECLDWWFCYKKLD
CCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEHHEEHHHHCC
>Mature Secondary Structure
MCEGKMPVIGEKFPEVEVKTTHGAIKLPDYYVEKGKWFVLFSHPADFTPVCTTEFVGFQK
CCCCCCCCCCCCCCCEEEEECCCEEECCHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHH
RYDEFRKLNTELIGLSIDQVFSHLKWVEWIKEKLNVEIEFPIIADDRGELAEKLGMISPY
HHHHHHHHCHHHEEEEHHHHHHHHHHHHHHHHHCCEEEEEEEEECCHHHHHHHHCCCCCC
KGNNTVRAVFVVDNKGIIRAIIYYPQEVGRNLDEIVRLVKALQVSDEKGVAMPANWPEND
CCCCEEEEEEEECCCCEEEHEEECCHHHCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCC
LIGDKVIIPPASSVEEIKQRKEACEKGEIECLDWWFCYKKLD
CCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEHHEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]