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The map label for this gene is yneB [C]

Identifier: 15668576

GI number: 15668576

Start: 361590

End: 362411

Strand: Direct

Name: yneB [C]

Synonym: MJ0400

Alternate gene names: 15668576

Gene position: 361590-362411 (Clockwise)

Preceding gene: 15668574

Following gene: 15668579

Centisome position: 21.72

GC content: 39.42

Gene sequence:

>822_bases
ATGGAATTATTTAAAGACATAAAGAATCTTGGAAAACTTGTAAGGTTGGAGAGAATATTTAACAGAGAAAGTGAAAAAAC
TGTAATTGTTCCAATGGACCATGGGGTATCAAACGGTCCAATTAAGGGGCTTATAGATATAAGAAAAACCGTAAATGATG
TTGCCGAAGGAGGAGCTAATGCTGTCCTCTTACATAAGGGAATTGTAAGACATGGACACAGAGGATATGGCAAAGATGTT
GGTTTAATCATCCATCTCTCTGGTGGAACTGCAATATCACCAAATCCATTGAAGAAGGTTATTGTTACAACTGTTGAAGA
AGCTATCAGAATGGGTGCTGATGCTGTCTCAATTCACGTAAATGTTGGTTCAGATGAAGATTGGGAAGCATACAGAGATT
TGGGGATGATAGCTGAAACATGTGAATACTGGGGAATGCCGTTAATTGCTATGATGTATCCAAGAGGAAAACACATTCAA
AATGAGAGAGACCCTGAATTAGTTGCTCATGCAGCAAGATTGGGAGCTGAGTTAGGAGCTGACATAGTTAAAACAAGTTA
TACTGGAGATATTGATTCATTTAGAGATGTTGTTAAGGGTTGTCCAGCTCCAGTTGTGGTTGCTGGAGGGCCAAAGACAA
ACACAGATGAAGAGTTCTTGCAAATGATTAAAGATGCTATGGAGGCTGGAGCTGCTGGTGTTGCAGTGGGTAGAAATATC
TTCCAGCATGATGATGTTGTTGGCATAACAAGAGCTGTTTGTAAGATAGTCCATGAAAATGCAGACGTTGAGGAGGCGTT
AAAAGAGATTAGGAAGAAATAA

Upstream 100 bases:

>100_bases
TCACCAAACACAAATTTTAAATATTGATATCTGATATTTCTATATTAAAACTTTAACATTAATATCAAATAAAACAATAA
AAATTTGTAAATGTGAGAAT

Downstream 100 bases:

>100_bases
ATTCCTTTATTTTTATCCTTTTTATTTTAATTTTTTATTTTTAGATAAATATATTTAAATACTTAAATATAAAAAATAAA
AAAGAAATTTAAAAATTTTG

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: ADH synthase; ADHS; Transaldolase-like ADHS

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MELFKDIKNLGKLVRLERIFNRESEKTVIVPMDHGVSNGPIKGLIDIRKTVNDVAEGGANAVLLHKGIVRHGHRGYGKDV
GLIIHLSGGTAISPNPLKKVIVTTVEEAIRMGADAVSIHVNVGSDEDWEAYRDLGMIAETCEYWGMPLIAMMYPRGKHIQ
NERDPELVAHAARLGAELGADIVKTSYTGDIDSFRDVVKGCPAPVVVAGGPKTNTDEEFLQMIKDAMEAGAAGVAVGRNI
FQHDDVVGITRAVCKIVHENADVEEALKEIRKK

Sequences:

>Translated_273_residues
MELFKDIKNLGKLVRLERIFNRESEKTVIVPMDHGVSNGPIKGLIDIRKTVNDVAEGGANAVLLHKGIVRHGHRGYGKDV
GLIIHLSGGTAISPNPLKKVIVTTVEEAIRMGADAVSIHVNVGSDEDWEAYRDLGMIAETCEYWGMPLIAMMYPRGKHIQ
NERDPELVAHAARLGAELGADIVKTSYTGDIDSFRDVVKGCPAPVVVAGGPKTNTDEEFLQMIKDAMEAGAAGVAVGRNI
FQHDDVVGITRAVCKIVHENADVEEALKEIRKK
>Mature_273_residues
MELFKDIKNLGKLVRLERIFNRESEKTVIVPMDHGVSNGPIKGLIDIRKTVNDVAEGGANAVLLHKGIVRHGHRGYGKDV
GLIIHLSGGTAISPNPLKKVIVTTVEEAIRMGADAVSIHVNVGSDEDWEAYRDLGMIAETCEYWGMPLIAMMYPRGKHIQ
NERDPELVAHAARLGAELGADIVKTSYTGDIDSFRDVVKGCPAPVVVAGGPKTNTDEEFLQMIKDAMEAGAAGVAVGRNI
FQHDDVVGITRAVCKIVHENADVEEALKEIRKK

Specific function: Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH). Plays a key role

COG id: COG1830

COG function: function code G; DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. ADHS subfamily

Homologues:

Organism=Escherichia coli, GI1787796, Length=260, Percent_Identity=31.9230769230769, Blast_Score=128, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADHS_METJA (Q57843)

Other databases:

- EMBL:   L77117
- PIR:   H64349
- RefSeq:   NP_247374.1
- PDB:   2QJG
- PDB:   2QJH
- PDB:   2QJI
- PDBsum:   2QJG
- PDBsum:   2QJH
- PDBsum:   2QJI
- ProteinModelPortal:   Q57843
- SMR:   Q57843
- GeneID:   1451260
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0400
- NMPDR:   fig|243232.1.peg.411
- TIGR:   MJ0400
- HOGENOM:   HBG553580
- OMA:   VRHGHRG
- ProtClustDB:   PRK07226
- BioCyc:   MetaCyc:MONOMER-14592
- BioCyc:   MJAN243232:MJ_0400-MONOMER
- InterPro:   IPR013785
- InterPro:   IPR010210
- InterPro:   IPR002915
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01949

Pfam domain/function: PF01791 DeoC

EC number: 4.2.1.- [C]

Molecular weight: Translated: 29676; Mature: 29676

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: ACT_SITE 33-33 ACT_SITE 153-153 ACT_SITE 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELFKDIKNLGKLVRLERIFNRESEKTVIVPMDHGVSNGPIKGLIDIRKTVNDVAEGGAN
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCC
AVLLHKGIVRHGHRGYGKDVGLIIHLSGGTAISPNPLKKVIVTTVEEAIRMGADAVSIHV
EEEEHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEE
NVGSDEDWEAYRDLGMIAETCEYWGMPLIAMMYPRGKHIQNERDPELVAHAARLGAELGA
ECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCH
DIVKTSYTGDIDSFRDVVKGCPAPVVVAGGPKTNTDEEFLQMIKDAMEAGAAGVAVGRNI
HHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
FQHDDVVGITRAVCKIVHENADVEEALKEIRKK
HHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MELFKDIKNLGKLVRLERIFNRESEKTVIVPMDHGVSNGPIKGLIDIRKTVNDVAEGGAN
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCC
AVLLHKGIVRHGHRGYGKDVGLIIHLSGGTAISPNPLKKVIVTTVEEAIRMGADAVSIHV
EEEEHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEE
NVGSDEDWEAYRDLGMIAETCEYWGMPLIAMMYPRGKHIQNERDPELVAHAARLGAELGA
ECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCH
DIVKTSYTGDIDSFRDVVKGCPAPVVVAGGPKTNTDEEFLQMIKDAMEAGAAGVAVGRNI
HHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
FQHDDVVGITRAVCKIVHENADVEEALKEIRKK
HHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087