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The map label for this gene is 15668568

Identifier: 15668568

GI number: 15668568

Start: 355786

End: 356805

Strand: Direct

Name: 15668568

Synonym: MJ0392

Alternate gene names: NA

Gene position: 355786-356805 (Clockwise)

Preceding gene: 15668565

Following gene: 15668574

Centisome position: 21.37

GC content: 31.08

Gene sequence:

>1020_bases
ATGAATTACTCAATAAGATTATTCAAAATTATGGGGATTCCAATAGAGCTTCATATAACCTTTATTTTATTTTTAGTGGT
CATAATTGGACTGTCTATAATGAATAATAGCATATTTTGGGCAGTTCTCTTTATCTTATTATTTGTGTCTGTTGTTTTAC
ATGAGTTAGGTCATAGTTATGTAGCTAAGAAGTATGGGGTAAAGATAGAAAAAATTTTGCTATTGCCGATTGGTGGAGTG
GCGATGATGGATAAAATCCCAAAAGAGGGGGAGTTAAGGATAGGGATAGCTGGGCCTTTAGTTAGCTTTATTATTGGAAT
AGTTTTGTTAATTGTATCTCAATTTTTTGATATAAACATAAATGGATATCCTCTATTATATACTTTAAGCCTACTGAACT
TAATGCTTGGAGGATTTAATTTAATTCCAGCATTTCCTATGGATGGCGGAAGAATATTGAGAGCTATATTGTCAAAAAAA
TATGGTTATTTGAAATCAACGAAGATAGCAGCAAATATTGGAAAGAGCTTGGCTTTAATAATGCTCTTATTTGGTCTCTT
ATCAATGAACATTATATTAATCTTGGTTAGTTTGTTTGTTTATTTTGGAGCTGAGCAAGAAAGTAGAGTGGTAGAAGTTG
AGACAATATTTAAAAATATTAAGGCAAAGGACATTATGACGCCAAATCCAGTATATGTAACTCCAGATATGAGTATAGAG
GAGTTCTTGGATTTTATGCTTAAACATAAGTATTTTGGATATCCTGTAGTTGAAAATGGGAAGTTAGTTGGCTGTATTGG
AATAGGTAATATACATAAAAAAGAAGGAACTGTAAGGGATTATATGGAAAAGCCTGTTGTAGTTAGTGAAGATACTGATA
TAAAAGAGATTCTAAGAAAAATGGCTAATACAGATAGAGTATTTGTTGTAGAAGGTGGAAAATTAAAAGGAATCATATCA
AAAACAGATATCTTGAGGGCTATGAGTATATTGGAGTTAAAAGAAGAGCTAAAAGATTAA

Upstream 100 bases:

>100_bases
CTGGAATCATATATTTCACCGAATCATAAATATGTTATGAAATAGTAATATATAGCAATAGGATTAAAAATGTAATTAAA
ATAAAAATAGGGGGAGGGGT

Downstream 100 bases:

>100_bases
CTTACTCCTTCTTTTGTGGTTGCTTCCATTCCATGTAGCCACATTTTCCACATGCGTATCTGTTTAAGTGCTCAGCCATG
AAAACTCCAGGACCACATCT

Product: hypothetical protein

Products: NA

Alternate protein names: Site-2-type intermembrane protease

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNYSIRLFKIMGIPIELHITFILFLVVIIGLSIMNNSIFWAVLFILLFVSVVLHELGHSYVAKKYGVKIEKILLLPIGGV
AMMDKIPKEGELRIGIAGPLVSFIIGIVLLIVSQFFDININGYPLLYTLSLLNLMLGGFNLIPAFPMDGGRILRAILSKK
YGYLKSTKIAANIGKSLALIMLLFGLLSMNIILILVSLFVYFGAEQESRVVEVETIFKNIKAKDIMTPNPVYVTPDMSIE
EFLDFMLKHKYFGYPVVENGKLVGCIGIGNIHKKEGTVRDYMEKPVVVSEDTDIKEILRKMANTDRVFVVEGGKLKGIIS
KTDILRAMSILELKEELKD

Sequences:

>Translated_339_residues
MNYSIRLFKIMGIPIELHITFILFLVVIIGLSIMNNSIFWAVLFILLFVSVVLHELGHSYVAKKYGVKIEKILLLPIGGV
AMMDKIPKEGELRIGIAGPLVSFIIGIVLLIVSQFFDININGYPLLYTLSLLNLMLGGFNLIPAFPMDGGRILRAILSKK
YGYLKSTKIAANIGKSLALIMLLFGLLSMNIILILVSLFVYFGAEQESRVVEVETIFKNIKAKDIMTPNPVYVTPDMSIE
EFLDFMLKHKYFGYPVVENGKLVGCIGIGNIHKKEGTVRDYMEKPVVVSEDTDIKEILRKMANTDRVFVVEGGKLKGIIS
KTDILRAMSILELKEELKD
>Mature_339_residues
MNYSIRLFKIMGIPIELHITFILFLVVIIGLSIMNNSIFWAVLFILLFVSVVLHELGHSYVAKKYGVKIEKILLLPIGGV
AMMDKIPKEGELRIGIAGPLVSFIIGIVLLIVSQFFDININGYPLLYTLSLLNLMLGGFNLIPAFPMDGGRILRAILSKK
YGYLKSTKIAANIGKSLALIMLLFGLLSMNIILILVSLFVYFGAEQESRVVEVETIFKNIKAKDIMTPNPVYVTPDMSIE
EFLDFMLKHKYFGYPVVENGKLVGCIGIGNIHKKEGTVRDYMEKPVVVSEDTDIKEILRKMANTDRVFVVEGGKLKGIIS
KTDILRAMSILELKEELKD

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y392_METJA (Q57837)

Other databases:

- EMBL:   L77117
- PIR:   H64348
- RefSeq:   NP_247366.1
- PDB:   3B4R
- PDBsum:   3B4R
- ProteinModelPortal:   Q57837
- SMR:   Q57837
- MEROPS:   M50.006
- GeneID:   1451249
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0392
- NMPDR:   fig|243232.1.peg.403
- TIGR:   MJ0392
- HOGENOM:   HBG688956
- OMA:   FGASQEY
- ProtClustDB:   CLSK876166
- BioCyc:   MJAN243232:MJ_0392-MONOMER
- GO:   GO:0006508
- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR008915
- InterPro:   IPR016483
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF006404
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF02163 Peptidase_M50

EC number: NA

Molecular weight: Translated: 37966; Mature: 37966

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS51371 CBS; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 55-55

Signals:

None

Transmembrane regions:

HASH(0x406d4ba4)-; HASH(0xc50bebc)-; HASH(0xcb0bb5c)-; HASH(0xcc680fc)-; HASH(0xc3814e8)-; HASH(0xcbefcb0)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSIRLFKIMGIPIELHITFILFLVVIIGLSIMNNSIFWAVLFILLFVSVVLHELGHSY
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHH
VAKKYGVKIEKILLLPIGGVAMMDKIPKEGELRIGIAGPLVSFIIGIVLLIVSQFFDINI
HHHHHCCEEEEEEEEECCCHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCC
NGYPLLYTLSLLNLMLGGFNLIPAFPMDGGRILRAILSKKYGYLKSTKIAANIGKSLALI
CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MLLFGLLSMNIILILVSLFVYFGAEQESRVVEVETIFKNIKAKDIMTPNPVYVTPDMSIE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHCCCCCCCCCCCCEEECCCCCHH
EFLDFMLKHKYFGYPVVENGKLVGCIGIGNIHKKEGTVRDYMEKPVVVSEDTDIKEILRK
HHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCCCCCHHHHHHCCEEEECCCCHHHHHHH
MANTDRVFVVEGGKLKGIISKTDILRAMSILELKEELKD
HCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNYSIRLFKIMGIPIELHITFILFLVVIIGLSIMNNSIFWAVLFILLFVSVVLHELGHSY
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHH
VAKKYGVKIEKILLLPIGGVAMMDKIPKEGELRIGIAGPLVSFIIGIVLLIVSQFFDINI
HHHHHCCEEEEEEEEECCCHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCC
NGYPLLYTLSLLNLMLGGFNLIPAFPMDGGRILRAILSKKYGYLKSTKIAANIGKSLALI
CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MLLFGLLSMNIILILVSLFVYFGAEQESRVVEVETIFKNIKAKDIMTPNPVYVTPDMSIE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHCCCCCCCCCCCCEEECCCCCHH
EFLDFMLKHKYFGYPVVENGKLVGCIGIGNIHKKEGTVRDYMEKPVVVSEDTDIKEILRK
HHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCCCCCHHHHHHCCEEEECCCCHHHHHHH
MANTDRVFVVEGGKLKGIISKTDILRAMSILELKEELKD
HCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087