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The map label for this gene is yicO [C]

Identifier: 15668500

GI number: 15668500

Start: 302242

End: 303552

Strand: Direct

Name: yicO [C]

Synonym: MJ0326

Alternate gene names: 15668500

Gene position: 302242-303552 (Clockwise)

Preceding gene: 298575371

Following gene: 15668501

Centisome position: 18.15

GC content: 35.39

Gene sequence:

>1311_bases
GTGATTATGAAATTTGTTGAAAAATACTTTGAATTTGAGAAGTATGGGACTAATCTAAAGGTAGAAACCCTTGCAGGAAT
AACTACATTTATGACCATGGCATATATAATATTTGTCAATCCACAGATTTTGAGTACTGCAGGTATGGATTTTGGAGCAG
TTATGGTTGCTACTTGTATTGCTTCAGCAATTGCAACTTTAGTTATGGGATTATATGCAAGATATCCATTTGCCTTAGCT
CCAGGAATGGGATTAAACGCTTATTTTACCTATGGGGTTTGCTTAGGAATGGGAATTGATTGGAGAGTTGCCTTAGGTGC
TGTTTTCATCTCTGGAGTGCTCTTTATAATATTAACATTAACAAAGATAAGAACATGGATTTTTAATGTTATTCCAAATG
CTATAAAGTATGGAACTGCTGTTGGTATTGGTTTATTTATTGCGTTTATTGGGTTAAAAAGTGCTGGTATCATAGTTAGT
AGTAAAGCTACATTAGTTACATTAGGGAATTTAATGGAGCCATCTACACTGTTGGCGTTGTTTGGGATATTTTTGACATC
AATCTTAGTTAGTAGGAATGTTATTGGAGCTATATTAATTGGAATTATAGTAACTTCGCTAATAGGAATGATTTTAGGAA
TTTCACCATTCCCAGAAGGAATATTCTCAATGCCTCCATCAATTGCACCAACATTCTTACAGCTTGATATAATGGGGGCT
TTAAACTTAGGTTTATTGACAATAGTCTTGGCATTCTTCTTTGTTGATATGTTTGACACTTTGGGAACTTTAAGTGCTTT
AGCCTCTCAGGCTGGATATTTAGATAAAGATGGAAAACTGCCAAGGGTTGAAAAGGCTTTAATGGCTGATGCTACTGGAA
CAGTTGTTGGTTCTCTCTTGGGAACTTCAACTGTAACAACCTATATAGAATCTGCAAGTGGTATAGCACTTGGAGGAAGA
ACAGGTTTTGTTTCAGTAGTTGTGGCTATGTTGTTTTTATTATCTTTATTTTTCTATCCAGTAGTTAAGGCAATTCCCCC
CTATGCAACAGCAGCAGCACTTGTCATTGTAGGAGCTTTAATGATGAGGTCAGTAAAATACATCGACTTTGATGACTACA
CAGAGGCAATTCCTGCATTTATAACTTTGCTAACTATTCCTTTGACATTTAGTATAGCTACAGGTCTCGCCTTAGGATTT
ATAACATATCCAATCTTAAAGGTATTTACTGGAAGATGGAAGGAAGTACATTGGCTTGTATATGTTTTAGCCGTAATATT
CGCTTTAAGATTTGTATATCTTTCGGGGTAA

Upstream 100 bases:

>100_bases
TAACTATTTAAGAGCTAACTATAACCTTATTATTTTATATTAATTGAAGATTTTATAAAACATTAGATTACATAAATAAA
CCATTATAACAAATGGAGGG

Downstream 100 bases:

>100_bases
AGTATTTAAATAACCTTAAATTATCTTATATCTCCTATTTTCCAAATCATATTTTGTGAGTTGATAAATATGAAAGTAGC
CATTTCAATGGATGTTGATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MIMKFVEKYFEFEKYGTNLKVETLAGITTFMTMAYIIFVNPQILSTAGMDFGAVMVATCIASAIATLVMGLYARYPFALA
PGMGLNAYFTYGVCLGMGIDWRVALGAVFISGVLFIILTLTKIRTWIFNVIPNAIKYGTAVGIGLFIAFIGLKSAGIIVS
SKATLVTLGNLMEPSTLLALFGIFLTSILVSRNVIGAILIGIIVTSLIGMILGISPFPEGIFSMPPSIAPTFLQLDIMGA
LNLGLLTIVLAFFFVDMFDTLGTLSALASQAGYLDKDGKLPRVEKALMADATGTVVGSLLGTSTVTTYIESASGIALGGR
TGFVSVVVAMLFLLSLFFYPVVKAIPPYATAAALVIVGALMMRSVKYIDFDDYTEAIPAFITLLTIPLTFSIATGLALGF
ITYPILKVFTGRWKEVHWLVYVLAVIFALRFVYLSG

Sequences:

>Translated_436_residues
MIMKFVEKYFEFEKYGTNLKVETLAGITTFMTMAYIIFVNPQILSTAGMDFGAVMVATCIASAIATLVMGLYARYPFALA
PGMGLNAYFTYGVCLGMGIDWRVALGAVFISGVLFIILTLTKIRTWIFNVIPNAIKYGTAVGIGLFIAFIGLKSAGIIVS
SKATLVTLGNLMEPSTLLALFGIFLTSILVSRNVIGAILIGIIVTSLIGMILGISPFPEGIFSMPPSIAPTFLQLDIMGA
LNLGLLTIVLAFFFVDMFDTLGTLSALASQAGYLDKDGKLPRVEKALMADATGTVVGSLLGTSTVTTYIESASGIALGGR
TGFVSVVVAMLFLLSLFFYPVVKAIPPYATAAALVIVGALMMRSVKYIDFDDYTEAIPAFITLLTIPLTFSIATGLALGF
ITYPILKVFTGRWKEVHWLVYVLAVIFALRFVYLSG
>Mature_436_residues
MIMKFVEKYFEFEKYGTNLKVETLAGITTFMTMAYIIFVNPQILSTAGMDFGAVMVATCIASAIATLVMGLYARYPFALA
PGMGLNAYFTYGVCLGMGIDWRVALGAVFISGVLFIILTLTKIRTWIFNVIPNAIKYGTAVGIGLFIAFIGLKSAGIIVS
SKATLVTLGNLMEPSTLLALFGIFLTSILVSRNVIGAILIGIIVTSLIGMILGISPFPEGIFSMPPSIAPTFLQLDIMGA
LNLGLLTIVLAFFFVDMFDTLGTLSALASQAGYLDKDGKLPRVEKALMADATGTVVGSLLGTSTVTTYIESASGIALGGR
TGFVSVVVAMLFLLSLFFYPVVKAIPPYATAAALVIVGALMMRSVKYIDFDDYTEAIPAFITLLTIPLTFSIATGLALGF
ITYPILKVFTGRWKEVHWLVYVLAVIFALRFVYLSG

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily

Homologues:

Organism=Escherichia coli, GI87082309, Length=427, Percent_Identity=46.3700234192037, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI1790150, Length=430, Percent_Identity=45.3488372093023, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1790499, Length=425, Percent_Identity=38.1176470588235, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI48994909, Length=418, Percent_Identity=38.0382775119617, Blast_Score=250, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y326_METJA (Q57772)

Other databases:

- EMBL:   L77117
- PIR:   F64340
- RefSeq:   NP_247298.1
- ProteinModelPortal:   Q57772
- GeneID:   1451180
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0326
- NMPDR:   fig|243232.1.peg.335
- TIGR:   MJ0326
- HOGENOM:   HBG750189
- OMA:   KIVDAIP
- ProtClustDB:   CLSK876160
- BioCyc:   MJAN243232:MJ_0326-MONOMER
- InterPro:   IPR006043
- PANTHER:   PTHR11119

Pfam domain/function: PF00860 Xan_ur_permease

EC number: NA

Molecular weight: Translated: 46724; Mature: 46724

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcb99b50)-; HASH(0xb320938)-; HASH(0xca8acfc)-; HASH(0xca1439c)-; HASH(0xc22f4e0)-; HASH(0xc39669c)-; HASH(0xca6f730)-; HASH(0xc9d5220)-; HASH(0xb612370)-; HASH(0xc796bb0)-; HASH(0xc820a14)-; HASH(0xb13b398)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCH
>Mature Secondary Structure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HHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087