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The map label for this gene is pyrF [H]

Identifier: 15668427

GI number: 15668427

Start: 238783

End: 239487

Strand: Direct

Name: pyrF [H]

Synonym: MJ0252

Alternate gene names: 15668427

Gene position: 238783-239487 (Clockwise)

Preceding gene: 15668425

Following gene: 15668428

Centisome position: 14.34

GC content: 32.62

Gene sequence:

>705_bases
TTGACATCAACTTTTTTATATAAATTTTATCCAAACTATAACGCAAAAAATTGCGGGGATAGGATGCCAAAGTTAATGTT
AGCTCTTGACGTTTTGGATAGAGATAGAGCTTTAAAAATAGTAGAAGATGTTAAAGATTACGTTGATGCTATAAAAGTTG
GATATCCTTTAGTTTTATCTACTGGGACAGAAATTATAAAAGAAATAAAAAAACTTTGTAATAAAGAGGTTATAGCTGAT
TTTAAGGTTGCAGACATCCCAGCAACAAATGAGAAGATAGCAAAAATAACATTAAAATATGCTGATGGAATAATAGTTCA
TGGTTTTGTTGGAGAGGATTCAGTTAAAGCAGTGCAAGATGTTGCTAAAAAGCTAAACAAAAAGGTAATAATGGTTACTG
AAATGAGCCATCCAGGGGCTGTTCAATTTCTACAGCCAATAGCAGATAAATTGTCAGAGATGGCTAAAAAACTAAAAGTT
GATGCTATAGTTGCTCCATCAACAAGGCCTGAAAGGCTTAAAGAAATTAAAGAAATTGCAGAATTGCCAGTAATAACACC
AGGAGTCGGAGCTCAGGGAGGGAAGATTGAGGATATTTTAAATATTTTAGATGAGAATGATTACGTCATTGTTGGAAGGG
CAATCTATCAATCACAAAATCCTAAAGAAGAGGCTAAAAAATATAAAGAAATGCTAAATAAGTGA

Upstream 100 bases:

>100_bases
TTATTTTCTTTAAAAGCTCTATTTTCTTTTCTAAATTTTCCATACTCTCACCAATAAATTCACAATATATAAAATATTCT
TAATATTAATTACAGTTAAT

Downstream 100 bases:

>100_bases
TAAAATGAAAAAGAAGGATATATTAATTGTTGGTTGTGGAAATCTGTTGTTTGGAGATGATGGCTTTGGATGTGAGGTTG
TTAGCAAATTAGAAAAAATG

Product: hypothetical protein

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTSTFLYKFYPNYNAKNCGDRMPKLMLALDVLDRDRALKIVEDVKDYVDAIKVGYPLVLSTGTEIIKEIKKLCNKEVIAD
FKVADIPATNEKIAKITLKYADGIIVHGFVGEDSVKAVQDVAKKLNKKVIMVTEMSHPGAVQFLQPIADKLSEMAKKLKV
DAIVAPSTRPERLKEIKEIAELPVITPGVGAQGGKIEDILNILDENDYVIVGRAIYQSQNPKEEAKKYKEMLNK

Sequences:

>Translated_234_residues
MTSTFLYKFYPNYNAKNCGDRMPKLMLALDVLDRDRALKIVEDVKDYVDAIKVGYPLVLSTGTEIIKEIKKLCNKEVIAD
FKVADIPATNEKIAKITLKYADGIIVHGFVGEDSVKAVQDVAKKLNKKVIMVTEMSHPGAVQFLQPIADKLSEMAKKLKV
DAIVAPSTRPERLKEIKEIAELPVITPGVGAQGGKIEDILNILDENDYVIVGRAIYQSQNPKEEAKKYKEMLNK
>Mature_233_residues
TSTFLYKFYPNYNAKNCGDRMPKLMLALDVLDRDRALKIVEDVKDYVDAIKVGYPLVLSTGTEIIKEIKKLCNKEVIADF
KVADIPATNEKIAKITLKYADGIIVHGFVGEDSVKAVQDVAKKLNKKVIMVTEMSHPGAVQFLQPIADKLSEMAKKLKVD
AIVAPSTRPERLKEIKEIAELPVITPGVGAQGGKIEDILNILDENDYVIVGRAIYQSQNPKEEAKKYKEMLNK

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 26108; Mature: 25977

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTFLYKFYPNYNAKNCGDRMPKLMLALDVLDRDRALKIVEDVKDYVDAIKVGYPLVLS
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEC
TGTEIIKEIKKLCNKEVIADFKVADIPATNEKIAKITLKYADGIIVHGFVGEDSVKAVQD
CCHHHHHHHHHHHCHHHHCCCEEECCCCCCCHHHEEEEEECCCEEEEEECCCHHHHHHHH
VAKKLNKKVIMVTEMSHPGAVQFLQPIADKLSEMAKKLKVDAIVAPSTRPERLKEIKEIA
HHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
ELPVITPGVGAQGGKIEDILNILDENDYVIVGRAIYQSQNPKEEAKKYKEMLNK
HCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TSTFLYKFYPNYNAKNCGDRMPKLMLALDVLDRDRALKIVEDVKDYVDAIKVGYPLVLS
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEC
TGTEIIKEIKKLCNKEVIADFKVADIPATNEKIAKITLKYADGIIVHGFVGEDSVKAVQD
CCHHHHHHHHHHHCHHHHCCCEEECCCCCCCHHHEEEEEECCCEEEEEECCCHHHHHHHH
VAKKLNKKVIMVTEMSHPGAVQFLQPIADKLSEMAKKLKVDAIVAPSTRPERLKEIKEIA
HHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
ELPVITPGVGAQGGKIEDILNILDENDYVIVGRAIYQSQNPKEEAKKYKEMLNK
HCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]