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The map label for this gene is rpl4lp

Identifier: 15668349

GI number: 15668349

Start: 179469

End: 180227

Strand: Direct

Name: rpl4lp

Synonym: MJ0177

Alternate gene names: 15668349

Gene position: 179469-180227 (Clockwise)

Preceding gene: 15668348

Following gene: 15668350

Centisome position: 10.78

GC content: 35.57

Gene sequence:

>759_bases
ATGAAGGCTGTTGTTTATAATTTAAATGGAGAGGCAGTAAAAGAAATTGACTTACCAGCAGTATTTGAAGAAGAATACAG
ACCAGATTTAATTAAGAGAGCTTTCTTATCTGCATTTACAGCAAGATTACAGCCAAAAGGTTCAGACCCATTGGCAGGAT
TAAGAACAAGTGCTAAAAACATTGGTAAAGGACACGGTAGGGCAAGAGTAGATAGAGTTCCACAAGGATGGGCTGCAAGA
GTTCCACAAGCAGTTGGTGGAAGAAGAGCACACCCACCAAAAGTTGAGAAAATATTATGGGAAAGAGTAAATAAAAAAGA
AAGAATTAAAGCAATAAAGAGTGCTATTGCAGCTACAGCAAACCCTGAATTAGTTAAAGAAAGAGGACATGTCTTTGAGA
CTGAAAATCTCCCAATTATTGTTGAAAGTTCATTTGAAGAGTTGCAAAAAACAAAAGATGTATTTGCAGTATTTGAAAAA
TTAGGAATCAGTGATGATGTTATAAGAGCTAAGAACGGAATTAAGATTAGAGCTGGAAAAGGTAAGATGAGAGGAAGAAA
ATACAAAAAACCAAGAAGTATCTTAGTTGTTGTTGGAGATAAATGCAACGCTATATTGGCTTCAAGAAACTTACCAGGAG
TTGATGTTATAACTGCTAAAGATTTGGGAATTATCCATTTAGCTCCTGGGGGAGTTGCTGGAAGATTAACCGTATGGACT
GAAAGTGCATTAGAGAAATTAAAAGAGAGATTTGAATAA

Upstream 100 bases:

>100_bases
CATTAATCAAAGTACCTGAAATTACATACATAAGTACAACATCAAAGCAAGGTAAGTAAATAAAATACTTTAAAATAATT
GAGAGAGAAGGTGAATAATA

Downstream 100 bases:

>100_bases
ATAAAATAAAAATGCAGAAACAAGGGGATAAAAATGGATGCCTTCGATGTAATAAAAGCTCCAGTAGTTACAGAAAAAAC
TGTTAGAATGATTGAAGAGG

Product: 50S ribosomal protein L4P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKAVVYNLNGEAVKEIDLPAVFEEEYRPDLIKRAFLSAFTARLQPKGSDPLAGLRTSAKNIGKGHGRARVDRVPQGWAAR
VPQAVGGRRAHPPKVEKILWERVNKKERIKAIKSAIAATANPELVKERGHVFETENLPIIVESSFEELQKTKDVFAVFEK
LGISDDVIRAKNGIKIRAGKGKMRGRKYKKPRSILVVVGDKCNAILASRNLPGVDVITAKDLGIIHLAPGGVAGRLTVWT
ESALEKLKERFE

Sequences:

>Translated_252_residues
MKAVVYNLNGEAVKEIDLPAVFEEEYRPDLIKRAFLSAFTARLQPKGSDPLAGLRTSAKNIGKGHGRARVDRVPQGWAAR
VPQAVGGRRAHPPKVEKILWERVNKKERIKAIKSAIAATANPELVKERGHVFETENLPIIVESSFEELQKTKDVFAVFEK
LGISDDVIRAKNGIKIRAGKGKMRGRKYKKPRSILVVVGDKCNAILASRNLPGVDVITAKDLGIIHLAPGGVAGRLTVWT
ESALEKLKERFE
>Mature_252_residues
MKAVVYNLNGEAVKEIDLPAVFEEEYRPDLIKRAFLSAFTARLQPKGSDPLAGLRTSAKNIGKGHGRARVDRVPQGWAAR
VPQAVGGRRAHPPKVEKILWERVNKKERIKAIKSAIAATANPELVKERGHVFETENLPIIVESSFEELQKTKDVFAVFEK
LGISDDVIRAKNGIKIRAGKGKMRGRKYKKPRSILVVVGDKCNAILASRNLPGVDVITAKDLGIIHLAPGGVAGRLTVWT
ESALEKLKERFE

Specific function: Forms part of the polypeptide exit tunnel

COG id: COG0088

COG function: function code J; Ribosomal protein L4

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L4P family

Homologues:

Organism=Homo sapiens, GI16579885, Length=255, Percent_Identity=37.2549019607843, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17508669, Length=252, Percent_Identity=36.1111111111111, Blast_Score=140, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6320215, Length=256, Percent_Identity=36.71875, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319505, Length=256, Percent_Identity=36.71875, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24650747, Length=245, Percent_Identity=35.5102040816327, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RL4_METJA (P54015)

Other databases:

- EMBL:   L77117
- PIR:   B64322
- RefSeq:   NP_247145.1
- ProteinModelPortal:   P54015
- SMR:   P54015
- GeneID:   1451024
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0177
- NMPDR:   fig|243232.1.peg.182
- TIGR:   MJ0177
- HOGENOM:   HBG316531
- OMA:   KMRGRRY
- ProtClustDB:   PRK04042
- BioCyc:   MJAN243232:MJ_0177-MONOMER
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_01328_A
- InterPro:   IPR002136
- InterPro:   IPR013000
- InterPro:   IPR019970
- TIGRFAMs:   TIGR03672

Pfam domain/function: PF00573 Ribosomal_L4; SSF52166 Ribosomal_L4/L1E

EC number: NA

Molecular weight: Translated: 27811; Mature: 27811

Theoretical pI: Translated: 10.78; Mature: 10.78

Prosite motif: PS00939 RIBOSOMAL_L1E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVYNLNGEAVKEIDLPAVFEEEYRPDLIKRAFLSAFTARLQPKGSDPLAGLRTSAKN
CCEEEEECCCCEEHHCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
IGKGHGRARVDRVPQGWAARVPQAVGGRRAHPPKVEKILWERVNKKERIKAIKSAIAATA
HCCCCCCHHHCCCCCCHHHHCCHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
NPELVKERGHVFETENLPIIVESSFEELQKTKDVFAVFEKLGISDDVIRAKNGIKIRAGK
CHHHHHHCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECC
GKMRGRKYKKPRSILVVVGDKCNAILASRNLPGVDVITAKDLGIIHLAPGGVAGRLTVWT
CCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCEEEEECCCCEEEECCCCCCCEEEEHH
ESALEKLKERFE
HHHHHHHHHHCC
>Mature Secondary Structure
MKAVVYNLNGEAVKEIDLPAVFEEEYRPDLIKRAFLSAFTARLQPKGSDPLAGLRTSAKN
CCEEEEECCCCEEHHCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
IGKGHGRARVDRVPQGWAARVPQAVGGRRAHPPKVEKILWERVNKKERIKAIKSAIAATA
HCCCCCCHHHCCCCCCHHHHCCHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
NPELVKERGHVFETENLPIIVESSFEELQKTKDVFAVFEKLGISDDVIRAKNGIKIRAGK
CHHHHHHCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECC
GKMRGRKYKKPRSILVVVGDKCNAILASRNLPGVDVITAKDLGIIHLAPGGVAGRLTVWT
CCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCEEEEECCCCEEEECCCCCCCEEEEHH
ESALEKLKERFE
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087