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The map label for this gene is cdhA

Identifier: 15668325

GI number: 15668325

Start: 149782

End: 152106

Strand: Direct

Name: cdhA

Synonym: MJ0153

Alternate gene names: 15668325

Gene position: 149782-152106 (Clockwise)

Preceding gene: 15668324

Following gene: 15668326

Centisome position: 9.0

GC content: 38.32

Gene sequence:

>2325_bases
ATGGTTATGGGGAATAACGTAGAAATGGACATTAAAAAACTCCTTACACCATTAGTTAAGATGAAAAACGCAAACATATC
CATGAGTATAAAGTTTGGAGAAGAAGAGGAAGAAGAATGGGAACCAATGGGACCTACTCCAATGCCAAAAATCCCTACAT
TAAGACACTGGGACTTTAAGCTCTTAGAGAGATATCCTCCATTCTATATGCCAATCTGTGATTTATGCTGTCTCTGTACT
TTTGGAAAGTGTGATTTAAGCAGAGGGAAGAAAGGAGCTTGTGGTTTAAATATCAAAGCTCAACAGGCAAGAATTGTTTT
AATTGCCTGCTGTATTGGAGCGGCATGTCATGCTGGACATAGTAGGCATTTAGTTCATCACCTAATTGAGACGTTGGGAA
GAGATTATCCAATAGATTTGGGTAATGAAATAGAGGTTGAGGCACCAATAGCAAGGACAGTAACTGGTATTAAACCAAAA
ACACTTGGAGATTTAGAGAAAATCTTAGATTACTGTGAAGAGCAGATAACTCATTTATTATCAGCGGCACATACTGGGCA
GGAAGGGGATTACTTAGATTTTGAGAGTAAAGCGTTACATGCAGGAATGATTGATGATTTAGCAAGAGAAGCAGGAGATT
TGGCCCAAATAGTTGCCTACAACATGCCAAAAGGAGATGAAGATGCTCCTTTAATAGAATTAGGGTTTGGTTGCATAGAC
AAGAGTAAGCCAGTTATCTTGTGTATTGGGCATAACGTAGTCCCAGGTAGCTACATATTAGAGTATTTAGAAGAAAACAG
TATGGAGGATGAAGTAGAGGTCTGCGGTATCTGTTGTACAGCTATAGACATCACAAGGGTTTCAGATAAACCAAAGGTTG
TAGGGCCTTTATCAAGGCAGTTGATGTTTGTAAGAAGTGGGGTTGCTGATGTTGTAATTGTAGATGAGCAGTGTATTAGA
ACAGATATCTTAGAGGAGGTTTTAAAAACTGGAGCTGTCTTGATAGCAACAAATGAGAAGATGTGTTTGGGATTAGAGGA
TGTTTCCCACATGGATGAGGATGAAATTATAGGCTATTTATTGAGAAATAGGGCAGCTTTACTCTTAGATGAGAAGAAAG
TTGGAAAAGTTGCTGTTGAAGTTGCTAAAATAGTTGCTAAGGAGAGAAAGGATAGAAAAACCCTACCAGATTTAAATGAA
GTTGTTGAGTTGGCAAAACAATGCACTGAATGTGGATGGTGCAACAGAAACTGTCCAAATGCATTTAAAGTTAAGGAAGC
AATGGCTTTAGCAAAACAGGGTAATTTTAAAGGATTCATTGATTTGTATAAGAGATGTTATGGCTGTGGAAGATGTGAAG
CTATCTGTCCAAGGAATTTGCCAATAGTTAGCATGACTACAAAGGTTGGAGAGGCATACTATAAAGACTTAAAGTTCAAG
ATGAGGGCTGGAAGAGGGCCTATAAAAGATGTTGAAATTAGAAGTGTTGGAGCTCCAATTGTATTTGGAGATATTCCTGG
AGTTGTTGCTTTAGTTGGATGTTCAAACCATCCAAATGGTGAGGAAGAAGTAGCGATGATTGCAAAGGAGTTCTTGGAGA
GGAAGTATATAGTTGTAGCAACTGGTTGTGCAGCAATGGCAATTGGAATGTGGAAAGATAAAGATGGAAAAACATTATAT
GAGAAGTATCCAGGTGAATTTAGGGCTGGAGGTCTTGTAAATTGTGGTTCTTGTCTCTCAAACTGCCACATTACTGGAGC
TGCTATAAAAATTGCCAACATCTTTGCCAAAGTTCCGTTGAGAGGAAACTATGCTGAAGTTGCAGATTACATACTAAACA
AAGTTGGAGCTGTTGGTGTTGCATGGGGTGCTATGAGTCAAAAGGCTGCTGCAATTGCTACTGGAGTCAATAGATGGGGA
ATCCCTGTTATTTTAGGCCCTCATGGAGCTAAGTATAGAAGGCTGTATTTAAGCAATGGAGAGAAATTCAAAGTTAAAGA
TAAAAAAACAGGAGAAATTTTGGAGATAGAGCCAGCTCCAGAGCATTTGATTGTAACTGCTGAGAATGTTAAAGAATGCA
TCTGCATGATTCCAAAGCTATGTATGAGGCCAAACGATACTCCAAAAGGTAGAGCCAATAAGATTTACCACTACGTTGAT
GTCTATGAAAAATACTTTGGAAGAATGCCTCCAGATTTAGAGAAATTCGTTAGAACTGAAAAAGACATCCCATTTATGAT
GAAAGATAAGATAATGGCATACTTAGAAGAAAAAGGATGGAAGCCATTGGAGAAATATCCACAAGACCCAACAATATTGT
ATTAA

Upstream 100 bases:

>100_bases
TTTCATACCAAACTTGGCTTTAGTCATAACAAACTTTATATATTAAAGTTTTAAAAACTAACCTTAAATTATAATGATTA
ATCATGACAATTAAGAAGTG

Downstream 100 bases:

>100_bases
CTCCTAATTCTTTTACTTTAAATTTCTGAAGTTGGTGATAGTAATGGATGAGAGATTTATTGCCTATATCCCAACAGCTG
GGAGCAATGTAGCACATGCT

Product: acetyl-CoA decarbonylase/synthase complex subunit alpha

Products: NA

Alternate protein names: ACDS complex subunit alpha; ACDS complex carbon monoxide dehydrogenase; ACDS CODH

Number of amino acids: Translated: 774; Mature: 774

Protein sequence:

>774_residues
MVMGNNVEMDIKKLLTPLVKMKNANISMSIKFGEEEEEEWEPMGPTPMPKIPTLRHWDFKLLERYPPFYMPICDLCCLCT
FGKCDLSRGKKGACGLNIKAQQARIVLIACCIGAACHAGHSRHLVHHLIETLGRDYPIDLGNEIEVEAPIARTVTGIKPK
TLGDLEKILDYCEEQITHLLSAAHTGQEGDYLDFESKALHAGMIDDLAREAGDLAQIVAYNMPKGDEDAPLIELGFGCID
KSKPVILCIGHNVVPGSYILEYLEENSMEDEVEVCGICCTAIDITRVSDKPKVVGPLSRQLMFVRSGVADVVIVDEQCIR
TDILEEVLKTGAVLIATNEKMCLGLEDVSHMDEDEIIGYLLRNRAALLLDEKKVGKVAVEVAKIVAKERKDRKTLPDLNE
VVELAKQCTECGWCNRNCPNAFKVKEAMALAKQGNFKGFIDLYKRCYGCGRCEAICPRNLPIVSMTTKVGEAYYKDLKFK
MRAGRGPIKDVEIRSVGAPIVFGDIPGVVALVGCSNHPNGEEEVAMIAKEFLERKYIVVATGCAAMAIGMWKDKDGKTLY
EKYPGEFRAGGLVNCGSCLSNCHITGAAIKIANIFAKVPLRGNYAEVADYILNKVGAVGVAWGAMSQKAAAIATGVNRWG
IPVILGPHGAKYRRLYLSNGEKFKVKDKKTGEILEIEPAPEHLIVTAENVKECICMIPKLCMRPNDTPKGRANKIYHYVD
VYEKYFGRMPPDLEKFVRTEKDIPFMMKDKIMAYLEEKGWKPLEKYPQDPTILY

Sequences:

>Translated_774_residues
MVMGNNVEMDIKKLLTPLVKMKNANISMSIKFGEEEEEEWEPMGPTPMPKIPTLRHWDFKLLERYPPFYMPICDLCCLCT
FGKCDLSRGKKGACGLNIKAQQARIVLIACCIGAACHAGHSRHLVHHLIETLGRDYPIDLGNEIEVEAPIARTVTGIKPK
TLGDLEKILDYCEEQITHLLSAAHTGQEGDYLDFESKALHAGMIDDLAREAGDLAQIVAYNMPKGDEDAPLIELGFGCID
KSKPVILCIGHNVVPGSYILEYLEENSMEDEVEVCGICCTAIDITRVSDKPKVVGPLSRQLMFVRSGVADVVIVDEQCIR
TDILEEVLKTGAVLIATNEKMCLGLEDVSHMDEDEIIGYLLRNRAALLLDEKKVGKVAVEVAKIVAKERKDRKTLPDLNE
VVELAKQCTECGWCNRNCPNAFKVKEAMALAKQGNFKGFIDLYKRCYGCGRCEAICPRNLPIVSMTTKVGEAYYKDLKFK
MRAGRGPIKDVEIRSVGAPIVFGDIPGVVALVGCSNHPNGEEEVAMIAKEFLERKYIVVATGCAAMAIGMWKDKDGKTLY
EKYPGEFRAGGLVNCGSCLSNCHITGAAIKIANIFAKVPLRGNYAEVADYILNKVGAVGVAWGAMSQKAAAIATGVNRWG
IPVILGPHGAKYRRLYLSNGEKFKVKDKKTGEILEIEPAPEHLIVTAENVKECICMIPKLCMRPNDTPKGRANKIYHYVD
VYEKYFGRMPPDLEKFVRTEKDIPFMMKDKIMAYLEEKGWKPLEKYPQDPTILY
>Mature_774_residues
MVMGNNVEMDIKKLLTPLVKMKNANISMSIKFGEEEEEEWEPMGPTPMPKIPTLRHWDFKLLERYPPFYMPICDLCCLCT
FGKCDLSRGKKGACGLNIKAQQARIVLIACCIGAACHAGHSRHLVHHLIETLGRDYPIDLGNEIEVEAPIARTVTGIKPK
TLGDLEKILDYCEEQITHLLSAAHTGQEGDYLDFESKALHAGMIDDLAREAGDLAQIVAYNMPKGDEDAPLIELGFGCID
KSKPVILCIGHNVVPGSYILEYLEENSMEDEVEVCGICCTAIDITRVSDKPKVVGPLSRQLMFVRSGVADVVIVDEQCIR
TDILEEVLKTGAVLIATNEKMCLGLEDVSHMDEDEIIGYLLRNRAALLLDEKKVGKVAVEVAKIVAKERKDRKTLPDLNE
VVELAKQCTECGWCNRNCPNAFKVKEAMALAKQGNFKGFIDLYKRCYGCGRCEAICPRNLPIVSMTTKVGEAYYKDLKFK
MRAGRGPIKDVEIRSVGAPIVFGDIPGVVALVGCSNHPNGEEEVAMIAKEFLERKYIVVATGCAAMAIGMWKDKDGKTLY
EKYPGEFRAGGLVNCGSCLSNCHITGAAIKIANIFAKVPLRGNYAEVADYILNKVGAVGVAWGAMSQKAAAIATGVNRWG
IPVILGPHGAKYRRLYLSNGEKFKVKDKKTGEILEIEPAPEHLIVTAENVKECICMIPKLCMRPNDTPKGRANKIYHYVD
VYEKYFGRMPPDLEKFVRTEKDIPFMMKDKIMAYLEEKGWKPLEKYPQDPTILY

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2)

COG id: COG1152

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDA_METJA (Q57617)

Other databases:

- EMBL:   L77117
- PIR:   B64319
- RefSeq:   NP_247121.1
- ProteinModelPortal:   Q57617
- SMR:   Q57617
- GeneID:   1450997
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0153
- NMPDR:   fig|243232.1.peg.158
- TIGR:   MJ0153
- HOGENOM:   HBG539676
- OMA:   ICCTAID
- ProtClustDB:   PRK00941
- BioCyc:   MJAN243232:MJ_0153-MONOMER
- BRENDA:   1.2.99.2
- GO:   GO:0005737
- HAMAP:   MF_01137
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR004460
- InterPro:   IPR012285
- InterPro:   IPR004137
- InterPro:   IPR011254
- InterPro:   IPR016099
- Gene3D:   G3DSA:1.10.1060.10
- Gene3D:   G3DSA:3.40.50.2030
- TIGRFAMs:   TIGR00314

Pfam domain/function: PF03063 Prismane; SSF56821 Prismane_like

EC number: =1.2.99.2

Molecular weight: Translated: 85901; Mature: 85901

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMGNNVEMDIKKLLTPLVKMKNANISMSIKFGEEEEEEWEPMGPTPMPKIPTLRHWDFK
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCHH
LLERYPPFYMPICDLCCLCTFGKCDLSRGKKGACGLNIKAQQARIVLIACCIGAACHAGH
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCEEHHHHHHHHHHHCCC
SRHLVHHLIETLGRDYPIDLGNEIEVEAPIARTVTGIKPKTLGDLEKILDYCEEQITHLL
HHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SAAHTGQEGDYLDFESKALHAGMIDDLAREAGDLAQIVAYNMPKGDEDAPLIELGFGCID
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCC
KSKPVILCIGHNVVPGSYILEYLEENSMEDEVEVCGICCTAIDITRVSDKPKVVGPLSRQ
CCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCEECHHHHH
LMFVRSGVADVVIVDEQCIRTDILEEVLKTGAVLIATNEKMCLGLEDVSHMDEDEIIGYL
HHHHHCCCCEEEEECHHHHHHHHHHHHHHCCEEEEEECCCEEEEHHHHHCCCHHHHHHHH
LRNRAALLLDEKKVGKVAVEVAKIVAKERKDRKTLPDLNEVVELAKQCTECGWCNRNCPN
HHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
AFKVKEAMALAKQGNFKGFIDLYKRCYGCGRCEAICPRNLPIVSMTTKVGEAYYKDLKFK
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
MRAGRGPIKDVEIRSVGAPIVFGDIPGVVALVGCSNHPNGEEEVAMIAKEFLERKYIVVA
HHCCCCCCCCEEEEECCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEE
TGCAAMAIGMWKDKDGKTLYEKYPGEFRAGGLVNCGSCLSNCHITGAAIKIANIFAKVPL
ECHHHHHCCCEECCCCCCHHHHCCCCCCCCCCCCHHHHHHCCEECHHHHHHHHHHHCCCC
RGNYAEVADYILNKVGAVGVAWGAMSQKAAAIATGVNRWGIPVILGPHGAKYRRLYLSNG
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEECCC
EKFKVKDKKTGEILEIEPAPEHLIVTAENVKECICMIPKLCMRPNDTPKGRANKIYHYVD
CEEEECCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VYEKYFGRMPPDLEKFVRTEKDIPFMMKDKIMAYLEEKGWKPLEKYPQDPTILY
HHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCC
>Mature Secondary Structure
MVMGNNVEMDIKKLLTPLVKMKNANISMSIKFGEEEEEEWEPMGPTPMPKIPTLRHWDFK
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCHH
LLERYPPFYMPICDLCCLCTFGKCDLSRGKKGACGLNIKAQQARIVLIACCIGAACHAGH
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCEEHHHHHHHHHHHCCC
SRHLVHHLIETLGRDYPIDLGNEIEVEAPIARTVTGIKPKTLGDLEKILDYCEEQITHLL
HHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SAAHTGQEGDYLDFESKALHAGMIDDLAREAGDLAQIVAYNMPKGDEDAPLIELGFGCID
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCC
KSKPVILCIGHNVVPGSYILEYLEENSMEDEVEVCGICCTAIDITRVSDKPKVVGPLSRQ
CCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCEECHHHHH
LMFVRSGVADVVIVDEQCIRTDILEEVLKTGAVLIATNEKMCLGLEDVSHMDEDEIIGYL
HHHHHCCCCEEEEECHHHHHHHHHHHHHHCCEEEEEECCCEEEEHHHHHCCCHHHHHHHH
LRNRAALLLDEKKVGKVAVEVAKIVAKERKDRKTLPDLNEVVELAKQCTECGWCNRNCPN
HHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
AFKVKEAMALAKQGNFKGFIDLYKRCYGCGRCEAICPRNLPIVSMTTKVGEAYYKDLKFK
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
MRAGRGPIKDVEIRSVGAPIVFGDIPGVVALVGCSNHPNGEEEVAMIAKEFLERKYIVVA
HHCCCCCCCCEEEEECCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEE
TGCAAMAIGMWKDKDGKTLYEKYPGEFRAGGLVNCGSCLSNCHITGAAIKIANIFAKVPL
ECHHHHHCCCEECCCCCCHHHHCCCCCCCCCCCCHHHHHHCCEECHHHHHHHHHHHCCCC
RGNYAEVADYILNKVGAVGVAWGAMSQKAAAIATGVNRWGIPVILGPHGAKYRRLYLSNG
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEECCC
EKFKVKDKKTGEILEIEPAPEHLIVTAENVKECICMIPKLCMRPNDTPKGRANKIYHYVD
CEEEECCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VYEKYFGRMPPDLEKFVRTEKDIPFMMKDKIMAYLEEKGWKPLEKYPQDPTILY
HHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087