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The map label for this gene is cdhE

Identifier: 15668283

GI number: 15668283

Start: 108691

End: 110157

Strand: Reverse

Name: cdhE

Synonym: MJ0112

Alternate gene names: 15668283

Gene position: 110157-108691 (Counterclockwise)

Preceding gene: 15668284

Following gene: 15668281

Centisome position: 6.62

GC content: 34.29

Gene sequence:

>1467_bases
ATGCCAAAAAAGATTAGTGCAATGGATATTTACAAATTACTGCCAAAAACAAACTGTAAAAAATGCGGTTATCCGTCATG
CATGGCATTTGCTACAAAACTGTTAGAGAAAGAGGCAACAATTGACCAATGTCCTATATTAAACACCCCAAAATTTGAGA
AAAATAAAAAGAAGATTATAGAGCTTATCTCTCCACCAGTAAAAGAAGTTTGGTTTGGGAACGAAGAAAAAAAGGCGGTT
ATGGGTGGAGACGAGGTAATGTATAGATATCAGTTATCATTCTTTAACCCTACACCAATTGGTGTTGATATTAGCGACGA
GTTAAGTGAAGAAGAAATTAAAAATAGAGCTAAGGAAATAGAGAACTTTGTATTTGAAAGAACTGGAGAAAAGTTAAAAT
TAGACTTTATTGTTATAAGAAATGCATCTGGAGATGTTGAGAAGTTTAAAAAAGCTATAGAAATTGTTGAAAAAGAAACA
AAGATGCCTATTTGCATTGCCTCATTAAATCCGGAGGTTATAAAGGAAGCTTTAAAAGTTGTTAAATCAAAGCCAATGGT
CTATGCCGCAACAAAAGAAACGTTAAATGATTTCATAAAGGTTATTAAAGAAGTTAAAAAGGACGTTGTTTTGGTTTTAT
CATCAAATAATGTTAAAGATTTAAAAAACATGGCTGCAAAGTGCTTAGCTAATGGTATTGAAGATTTAGTTTTAGAACCT
CACACATACCCAGAAAATATCGCTGAAACATTAGATTTGAATGTAATGATTAGGAGGAGTGCTATTGAGAAGGAAGATAA
ATACTTAGGATTTCCAATATTAAATTTACCAATTAACGCTTATTATTATGCTTTAAAAAATGAATGCCCAATCTCTGGAT
TTTTTGAGGATAAAGAGGTTGTTGCTAAGATGTTTGAGGCTACAATAGCCAATACATTGATGAACAGATATGCAGATGCT
TTAATTATGCATGGAATGGATATATGGGAATTAATGCCAGTCCTAACATTGAGACAGTGTATCTATACAGACCCAAGAAA
GCCACAGGCAGTTGAGCCAGGCTTATACCCAATTGGCAATCCAGACGAAAACAGCCCAGTTATATTAACAACAAACTTCT
CATTAACATTCTACACAGTTACAGGAGACTTTGAGAAAGATAACGTTACCTGCTGGCTATTGGTTATGGACACTGGAGGA
AAGGCTGTTGATGTTTCAGTTGCAGGAGGGCAGTATAATGGAGAAAATGCTAAAAAATTAATTGAAGAGACAGGAATCGC
TGATAAAGTTAGCCACAGGATAATAATATTGCCAGCTTTAGCTGCTTCTACAAGAGGAGATATTGAAGACAAAACCGGCT
GGACATGTGTTGTTGGAACAAGAGATTCATCTCAAGTTGGTGACTTCTTAAGAAATAACTGGGATAAGATATTAAAAGAA
TGGAAGGAGAAGAATCAAACAGCTTAA

Upstream 100 bases:

>100_bases
TTAGTTAAATACGTAAGATAAACACCAACAACTACGATTAGATTGTGGCAAAGGCATAAAATTGTAATATAATTGTAATT
ATTAATCTAAAGGTGATAGA

Downstream 100 bases:

>100_bases
ATACATTATTTAAATATTTTTATAAAAAAGAAAAATTGTAGGTTTGGAATTTCTGATTTTGTTGTTTGGTTTATTGATTG
TCTTGTTGAATATGTTTGGA

Product: acetyl-CoA decarbonylase/synthase complex subunit gamma

Products: CO2; AH2

Alternate protein names: ACDS complex subunit gamma; ACDS complex methyltransferase; Corrinoid/iron-sulfur component large subunit

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MPKKISAMDIYKLLPKTNCKKCGYPSCMAFATKLLEKEATIDQCPILNTPKFEKNKKKIIELISPPVKEVWFGNEEKKAV
MGGDEVMYRYQLSFFNPTPIGVDISDELSEEEIKNRAKEIENFVFERTGEKLKLDFIVIRNASGDVEKFKKAIEIVEKET
KMPICIASLNPEVIKEALKVVKSKPMVYAATKETLNDFIKVIKEVKKDVVLVLSSNNVKDLKNMAAKCLANGIEDLVLEP
HTYPENIAETLDLNVMIRRSAIEKEDKYLGFPILNLPINAYYYALKNECPISGFFEDKEVVAKMFEATIANTLMNRYADA
LIMHGMDIWELMPVLTLRQCIYTDPRKPQAVEPGLYPIGNPDENSPVILTTNFSLTFYTVTGDFEKDNVTCWLLVMDTGG
KAVDVSVAGGQYNGENAKKLIEETGIADKVSHRIIILPALAASTRGDIEDKTGWTCVVGTRDSSQVGDFLRNNWDKILKE
WKEKNQTA

Sequences:

>Translated_488_residues
MPKKISAMDIYKLLPKTNCKKCGYPSCMAFATKLLEKEATIDQCPILNTPKFEKNKKKIIELISPPVKEVWFGNEEKKAV
MGGDEVMYRYQLSFFNPTPIGVDISDELSEEEIKNRAKEIENFVFERTGEKLKLDFIVIRNASGDVEKFKKAIEIVEKET
KMPICIASLNPEVIKEALKVVKSKPMVYAATKETLNDFIKVIKEVKKDVVLVLSSNNVKDLKNMAAKCLANGIEDLVLEP
HTYPENIAETLDLNVMIRRSAIEKEDKYLGFPILNLPINAYYYALKNECPISGFFEDKEVVAKMFEATIANTLMNRYADA
LIMHGMDIWELMPVLTLRQCIYTDPRKPQAVEPGLYPIGNPDENSPVILTTNFSLTFYTVTGDFEKDNVTCWLLVMDTGG
KAVDVSVAGGQYNGENAKKLIEETGIADKVSHRIIILPALAASTRGDIEDKTGWTCVVGTRDSSQVGDFLRNNWDKILKE
WKEKNQTA
>Mature_487_residues
PKKISAMDIYKLLPKTNCKKCGYPSCMAFATKLLEKEATIDQCPILNTPKFEKNKKKIIELISPPVKEVWFGNEEKKAVM
GGDEVMYRYQLSFFNPTPIGVDISDELSEEEIKNRAKEIENFVFERTGEKLKLDFIVIRNASGDVEKFKKAIEIVEKETK
MPICIASLNPEVIKEALKVVKSKPMVYAATKETLNDFIKVIKEVKKDVVLVLSSNNVKDLKNMAAKCLANGIEDLVLEPH
TYPENIAETLDLNVMIRRSAIEKEDKYLGFPILNLPINAYYYALKNECPISGFFEDKEVVAKMFEATIANTLMNRYADAL
IMHGMDIWELMPVLTLRQCIYTDPRKPQAVEPGLYPIGNPDENSPVILTTNFSLTFYTVTGDFEKDNVTCWLLVMDTGGK
AVDVSVAGGQYNGENAKKLIEETGIADKVSHRIIILPALAASTRGDIEDKTGWTCVVGTRDSSQVGDFLRNNWDKILKEW
KEKNQTA

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2)

COG id: COG1456

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDG_METJA (Q57576)

Other databases:

- EMBL:   L77117
- PIR:   H64313
- RefSeq:   NP_247076.1
- ProteinModelPortal:   Q57576
- SMR:   Q57576
- GeneID:   1450953
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0112
- NMPDR:   fig|243232.1.peg.113
- TIGR:   MJ0112
- HOGENOM:   HBG304431
- OMA:   YTDPRKP
- ProtClustDB:   PRK04165
- BioCyc:   MJAN243232:MJ_0112-MONOMER
- HAMAP:   MF_01136
- InterPro:   IPR016041
- InterPro:   IPR016218
- InterPro:   IPR011005
- InterPro:   IPR007202
- InterPro:   IPR000489
- Gene3D:   G3DSA:3.20.20.20
- PIRSF:   PIRSF000376

Pfam domain/function: PF03599 CdhD; PF04060 FeS; SSF51717 DHP_synth_like

EC number: 1.2.99.2

Molecular weight: Translated: 55027; Mature: 54896

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00198 4FE4S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKISAMDIYKLLPKTNCKKCGYPSCMAFATKLLEKEATIDQCPILNTPKFEKNKKKII
CCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
ELISPPVKEVWFGNEEKKAVMGGDEVMYRYQLSFFNPTPIGVDISDELSEEEIKNRAKEI
HHHCCCHHHHHCCCCCCCEECCCCCEEEEEEEEECCCCCCCCCCHHHCCHHHHHHHHHHH
ENFVFERTGEKLKLDFIVIRNASGDVEKFKKAIEIVEKETKMPICIASLNPEVIKEALKV
HHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHH
VKSKPMVYAATKETLNDFIKVIKEVKKDVVLVLSSNNVKDLKNMAAKCLANGIEDLVLEP
HHCCCEEEEHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHCCHHHHHCCC
HTYPENIAETLDLNVMIRRSAIEKEDKYLGFPILNLPINAYYYALKNECPISGFFEDKEV
CCCHHHHHHHHCHHEEEEHHHHCCCCCEECCEEEECCCCCEEEEECCCCCCCCCCCCHHH
VAKMFEATIANTLMNRYADALIMHGMDIWELMPVLTLRQCIYTDPRKPQAVEPGLYPIGN
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PDENSPVILTTNFSLTFYTVTGDFEKDNVTCWLLVMDTGGKAVDVSVAGGQYNGENAKKL
CCCCCCEEEEEECEEEEEEEECCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCHHHHHH
IEETGIADKVSHRIIILPALAASTRGDIEDKTGWTCVVGTRDSSQVGDFLRNNWDKILKE
HHHCCCHHHHCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCHHHHHHH
WKEKNQTA
HHHCCCCC
>Mature Secondary Structure 
PKKISAMDIYKLLPKTNCKKCGYPSCMAFATKLLEKEATIDQCPILNTPKFEKNKKKII
CCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
ELISPPVKEVWFGNEEKKAVMGGDEVMYRYQLSFFNPTPIGVDISDELSEEEIKNRAKEI
HHHCCCHHHHHCCCCCCCEECCCCCEEEEEEEEECCCCCCCCCCHHHCCHHHHHHHHHHH
ENFVFERTGEKLKLDFIVIRNASGDVEKFKKAIEIVEKETKMPICIASLNPEVIKEALKV
HHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHH
VKSKPMVYAATKETLNDFIKVIKEVKKDVVLVLSSNNVKDLKNMAAKCLANGIEDLVLEP
HHCCCEEEEHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHCCHHHHHCCC
HTYPENIAETLDLNVMIRRSAIEKEDKYLGFPILNLPINAYYYALKNECPISGFFEDKEV
CCCHHHHHHHHCHHEEEEHHHHCCCCCEECCEEEECCCCCEEEEECCCCCCCCCCCCHHH
VAKMFEATIANTLMNRYADALIMHGMDIWELMPVLTLRQCIYTDPRKPQAVEPGLYPIGN
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PDENSPVILTTNFSLTFYTVTGDFEKDNVTCWLLVMDTGGKAVDVSVAGGQYNGENAKKL
CCCCCCEEEEEECEEEEEEEECCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCHHHHHH
IEETGIADKVSHRIIILPALAASTRGDIEDKTGWTCVVGTRDSSQVGDFLRNNWDKILKE
HHHCCCHHHHCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCHHHHHHH
WKEKNQTA
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CO; H2O; A

Specific reaction: CO + H2O + A = CO2 + AH2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087