Click here to switch to the map view.

The map label for this gene is mrtA

Identifier: 15668254

GI number: 15668254

Start: 76826

End: 78484

Strand: Direct

Name: mrtA

Synonym: MJ0083

Alternate gene names: 15668254

Gene position: 76826-78484 (Clockwise)

Preceding gene: 15668253

Following gene: 15668255

Centisome position: 4.61

GC content: 39.9

Gene sequence:

>1659_bases
ATGGATGTTGAGAAAAAACTCTTCCTAAAGGCTTTAAAAGAAAAGTTTGAAGAAGACCCAAAAGAAAAATACACCAAATT
TTATATATTTGGAGGATGGAGACAGTCAGCAAGAAAAAGAGAGTTTGTTGAATTTGCTCAAAAATTAATTGAAAAGAGAG
GAGGAATTCCATTCTACAACCCAGACATTGGGGTTCCATTAGGGCAGAGAAAGTTAATGACCTACAAAATATCAGGAACT
GATGCATTTGTTGAAGGGGATGATTTACACTTCTGTAATAACGCAGCAATACAGCAATTGGTTGATGATATTAAGAGAAC
TGTTATTGTAGGGATGGATACAGCTCACGCTGTCTTAGAGAAGAGATTAGGGGTAGAGGTTACACCAGAAACAATTAACG
AATACATGGAAACAATTAACCACGCTTTACCAGGTGGAGCTGTTGTCCAAGAGCACATGGTTGAAGTCCATCCAGGTTTA
GTTTGGGACTGTTACGCTAAGATATTCACAGGAAATGATGAATTAGCTGATGAAATTGACAAGAGATTTTTAATAGACAT
AAATAAAGAATTCCCAGAAGAACAAGCAGAGCAAATTAAGAAATATATTGGAAATAGGACTTACCAAGTAAGTAGGGTTC
CTACAATAGTTGTTAGATGCTGTGATGGAGGGACTGTTTCAAGATGGAGTGCTATGCAAATAGGGATGAGTTTCATTACT
GCCTATAAGTTATGTGCTGGAGAAGCTGCTATCGCTGACTTCTCATACGCTGCAAAGCACGCTGATGTCATTCAAATGGG
TATGATACTGCCAGCAAGAAGAGCAAGAGGGCCTAATGAACCAGGAGGGGTGCCATTTGGAATATTCGCTGACATAATAC
AGACTTCAAGAGTTTCAGATGACCCGGCACAGGTAACATTGGAGGTTATTGGTGCAGCAGCTACCTTTTATGACCAAGTT
TGGTTAGGAAGCTATATGTCTGGAGGAGTAGGATTTACACAGTATGCGTCAGCAACATACACAGATGACATCTTAGATGA
TTTTGTTTATTATGGAATGGACTATGTTGAGAAGAAGTATGGATTATGTGGAGTTAAGCCAAGCATGGAGGTTGTTAAAG
ATATAGCAACTGAAGTTACATTATATGGATTAGAGCAGTATGATGAGTATCCAGCTTTATTAGAAGACCACTTTGGTGGG
TCACAAAGAGCGGGGGTTACAGCGGCAGCAGCAGGATGTTCAGTAGCATTTGCAACAGGAAACTCAAATGCTGGAATTAA
TGGATGGTATCTAAGCCAGATATTACATAAGGAGTATCACAGCAGATTAGGATTCTATGGTTATGACTTACAAGACCAGT
GTGGAGCAGCTAACTCACTATCAATCAGAAGTGATGAAGGTTTATTGCATGAATGTAGAGGACCAAATTATCCAAACTAC
GCAATGAACGTTGGACATCAGCCAGAGTATGCTGGAATTGCCCAAGCTCCCCATGCGGCAAGGGGAGATGCATTTTGCTT
AAACCCAATAATTAAGGTAGCGTTTGCTGACGACAACTTGATATTTGACTTCAAGTGGCCAAGAAAATGTATAGCTAAAG
GGGCTCTAAGAGAGTTTGAGCCAGCTGGAGAGAGAGATTTAATCATTCCAGCAGCATAA

Upstream 100 bases:

>100_bases
CTTTAGAAGTTGTTCAAATAATCCATGAGGCAAGAACAAAAGGAGGATTTGGTTTAGAAGTATTTAAAAAAGATTTGAAA
AAGAGATTAGGTGAAGAATA

Downstream 100 bases:

>100_bases
TCTTTATTATCTTATTTTAAGTTTTATTTTTTGGACTTTATTTTTAATTTTAAAATTTTAATTGGAGGGCATAATAATAG
ATTCAAACATTTTATCAAAA

Product: methyl coenzyme M reductase II subunit MtrA

Products: NA

Alternate protein names: MCR II alpha; Coenzyme-B sulfoethylthiotransferase alpha

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MDVEKKLFLKALKEKFEEDPKEKYTKFYIFGGWRQSARKREFVEFAQKLIEKRGGIPFYNPDIGVPLGQRKLMTYKISGT
DAFVEGDDLHFCNNAAIQQLVDDIKRTVIVGMDTAHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPGL
VWDCYAKIFTGNDELADEIDKRFLIDINKEFPEEQAEQIKKYIGNRTYQVSRVPTIVVRCCDGGTVSRWSAMQIGMSFIT
AYKLCAGEAAIADFSYAAKHADVIQMGMILPARRARGPNEPGGVPFGIFADIIQTSRVSDDPAQVTLEVIGAAATFYDQV
WLGSYMSGGVGFTQYASATYTDDILDDFVYYGMDYVEKKYGLCGVKPSMEVVKDIATEVTLYGLEQYDEYPALLEDHFGG
SQRAGVTAAAAGCSVAFATGNSNAGINGWYLSQILHKEYHSRLGFYGYDLQDQCGAANSLSIRSDEGLLHECRGPNYPNY
AMNVGHQPEYAGIAQAPHAARGDAFCLNPIIKVAFADDNLIFDFKWPRKCIAKGALREFEPAGERDLIIPAA

Sequences:

>Translated_552_residues
MDVEKKLFLKALKEKFEEDPKEKYTKFYIFGGWRQSARKREFVEFAQKLIEKRGGIPFYNPDIGVPLGQRKLMTYKISGT
DAFVEGDDLHFCNNAAIQQLVDDIKRTVIVGMDTAHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPGL
VWDCYAKIFTGNDELADEIDKRFLIDINKEFPEEQAEQIKKYIGNRTYQVSRVPTIVVRCCDGGTVSRWSAMQIGMSFIT
AYKLCAGEAAIADFSYAAKHADVIQMGMILPARRARGPNEPGGVPFGIFADIIQTSRVSDDPAQVTLEVIGAAATFYDQV
WLGSYMSGGVGFTQYASATYTDDILDDFVYYGMDYVEKKYGLCGVKPSMEVVKDIATEVTLYGLEQYDEYPALLEDHFGG
SQRAGVTAAAAGCSVAFATGNSNAGINGWYLSQILHKEYHSRLGFYGYDLQDQCGAANSLSIRSDEGLLHECRGPNYPNY
AMNVGHQPEYAGIAQAPHAARGDAFCLNPIIKVAFADDNLIFDFKWPRKCIAKGALREFEPAGERDLIIPAA
>Mature_552_residues
MDVEKKLFLKALKEKFEEDPKEKYTKFYIFGGWRQSARKREFVEFAQKLIEKRGGIPFYNPDIGVPLGQRKLMTYKISGT
DAFVEGDDLHFCNNAAIQQLVDDIKRTVIVGMDTAHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPGL
VWDCYAKIFTGNDELADEIDKRFLIDINKEFPEEQAEQIKKYIGNRTYQVSRVPTIVVRCCDGGTVSRWSAMQIGMSFIT
AYKLCAGEAAIADFSYAAKHADVIQMGMILPARRARGPNEPGGVPFGIFADIIQTSRVSDDPAQVTLEVIGAAATFYDQV
WLGSYMSGGVGFTQYASATYTDDILDDFVYYGMDYVEKKYGLCGVKPSMEVVKDIATEVTLYGLEQYDEYPALLEDHFGG
SQRAGVTAAAAGCSVAFATGNSNAGINGWYLSQILHKEYHSRLGFYGYDLQDQCGAANSLSIRSDEGLLHECRGPNYPNY
AMNVGHQPEYAGIAQAPHAARGDAFCLNPIIKVAFADDNLIFDFKWPRKCIAKGALREFEPAGERDLIIPAA

Specific function: Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and an heterodisulfide

COG id: COG4058

COG function: function code H; Methyl coenzyme M reductase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MCRX_METJA (Q60391)

Other databases:

- EMBL:   L77117
- PIR:   C64310
- RefSeq:   NP_247047.1
- ProteinModelPortal:   Q60391
- SMR:   Q60391
- GeneID:   1450922
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0083
- NMPDR:   fig|243232.1.peg.84
- TIGR:   MJ0083
- HOGENOM:   HBG541009
- OMA:   DINKEFP
- ProtClustDB:   CLSK876061
- BioCyc:   MJAN243232:MJ_0083-MONOMER
- BRENDA:   2.8.4.1
- GO:   GO:0015948
- InterPro:   IPR022681
- InterPro:   IPR016212
- InterPro:   IPR008924
- InterPro:   IPR009047
- InterPro:   IPR003183
- InterPro:   IPR015811
- InterPro:   IPR015823
- InterPro:   IPR009024
- Gene3D:   G3DSA:1.20.840.10
- Gene3D:   G3DSA:3.90.390.10
- Gene3D:   G3DSA:3.30.70.470
- PIRSF:   PIRSF000262
- TIGRFAMs:   TIGR03256

Pfam domain/function: PF02249 MCR_alpha; PF02745 MCR_alpha_N; SSF48081 MCR_alpha_beta_C; SSF55088 MCR_fer_like

EC number: =2.8.4.1

Molecular weight: Translated: 61241; Mature: 61241

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVEKKLFLKALKEKFEEDPKEKYTKFYIFGGWRQSARKREFVEFAQKLIEKRGGIPFYN
CCCHHHHHHHHHHHHHHCCHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDIGVPLGQRKLMTYKISGTDAFVEGDDLHFCNNAAIQQLVDDIKRTVIVGMDTAHAVLE
CCCCCCCCCCEEEEEEECCCEEEECCCCCEECCHHHHHHHHHHHHHHEEECCCHHHHHHH
KRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPGLVWDCYAKIFTGNDELADEID
HHCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHC
KRFLIDINKEFPEEQAEQIKKYIGNRTYQVSRVPTIVVRCCDGGTVSRWSAMQIGMSFIT
HHEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHH
AYKLCAGEAAIADFSYAAKHADVIQMGMILPARRARGPNEPGGVPFGIFADIIQTSRVSD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
DPAQVTLEVIGAAATFYDQVWLGSYMSGGVGFTQYASATYTDDILDDFVYYGMDYVEKKY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHCHHHHHHHC
GLCGVKPSMEVVKDIATEVTLYGLEQYDEYPALLEDHFGGSQRAGVTAAAAGCSVAFATG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEECCCCEEEEEEC
NSNAGINGWYLSQILHKEYHSRLGFYGYDLQDQCGAANSLSIRSDEGLLHECRGPNYPNY
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEECCCCHHHHCCCCCCCCH
AMNVGHQPEYAGIAQAPHAARGDAFCLNPIIKVAFADDNLIFDFKWPRKCIAKGALREFE
HCCCCCCCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCEEEEECCCHHHHHHHHHHHCC
PAGERDLIIPAA
CCCCCCEEECCC
>Mature Secondary Structure
MDVEKKLFLKALKEKFEEDPKEKYTKFYIFGGWRQSARKREFVEFAQKLIEKRGGIPFYN
CCCHHHHHHHHHHHHHHCCHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDIGVPLGQRKLMTYKISGTDAFVEGDDLHFCNNAAIQQLVDDIKRTVIVGMDTAHAVLE
CCCCCCCCCCEEEEEEECCCEEEECCCCCEECCHHHHHHHHHHHHHHEEECCCHHHHHHH
KRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPGLVWDCYAKIFTGNDELADEID
HHCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHC
KRFLIDINKEFPEEQAEQIKKYIGNRTYQVSRVPTIVVRCCDGGTVSRWSAMQIGMSFIT
HHEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHH
AYKLCAGEAAIADFSYAAKHADVIQMGMILPARRARGPNEPGGVPFGIFADIIQTSRVSD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
DPAQVTLEVIGAAATFYDQVWLGSYMSGGVGFTQYASATYTDDILDDFVYYGMDYVEKKY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHCHHHHHHHC
GLCGVKPSMEVVKDIATEVTLYGLEQYDEYPALLEDHFGGSQRAGVTAAAAGCSVAFATG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEECCCCEEEEEEC
NSNAGINGWYLSQILHKEYHSRLGFYGYDLQDQCGAANSLSIRSDEGLLHECRGPNYPNY
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEECCCCHHHHCCCCCCCCH
AMNVGHQPEYAGIAQAPHAARGDAFCLNPIIKVAFADDNLIFDFKWPRKCIAKGALREFE
HCCCCCCCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCEEEEECCCHHHHHHHHHHHCC
PAGERDLIIPAA
CCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087