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The map label for this gene is 15668217

Identifier: 15668217

GI number: 15668217

Start: 47370

End: 48656

Strand: Reverse

Name: 15668217

Synonym: MJ0047

Alternate gene names: NA

Gene position: 48656-47370 (Counterclockwise)

Preceding gene: 15668219

Following gene: 15668216

Centisome position: 2.92

GC content: 31.39

Gene sequence:

>1287_bases
ATGGAAATTATATTTAGAGGAGCGGCGTTAGAAGTTGGAAGAAGTTGTATAGAAATAAAAACTGATAAAAGCAAAATACT
ATTAGATTGTGGGGTTAAGCTTGGAAAAGAAATAGAATATCCTATATTGGACAACTCCATAAGAGATGTTGATAAAGTTT
TTATCTCACATGCCCATTTAGACCATTCAGGGGCTTTACCAGTCCTATTTCATAGGAAGATGGATGTTCCAGTAATTACA
ACAGAATTATCAAAAAAATTAATTAAGGTTTTATTAAAAGATATGGTAAAAATAGCTGAAACAGAAAATAAAAAAATCCC
CTACAACAACCATGATGTAAAAGAAGCTATAAGGCATACAATCCCATTAAATTACAACGATAAAAAATACTACAAAGATT
TTTCCTATGAATTGTTTAGTGCTGGGCATATTCCAGGAAGTGCATCCATATTATTAAATTACCAAAATAACAAAACCATC
TTATACACTGGGGATGTAAAGTTGAGGGACACAAGATTAACCAAAGGAGCTGATTTAAGCTATACAAAGGATGATATTGA
TATCTTAATTATAGAATCAACTTATGGAAACAGCATACACCCAGATAGAAAAGCCGTAGAGTTGAGTTTTATAGAAAAGA
TAAAAGAGATTTTATTTAGGGGAGGAGTTGCTTTAATTCCGGTCTTTGCTGTTGATAGAGCTCAGGAAATATTATTAATT
TTAAATGACTACAACATAGATGCTCCAATTTACTTAGATGGAATGGCTGTAGAAGTTACAAAGTTAATGCTAAACTATAA
ACATATGCTAAATGAATCGTCTCAATTAGAAAAAGCTCTAAAAAATGTTAAAATAATTGAAAAATCAGAGGACAGGATTA
AAGCAATCGAAAACTTATCAAAAAATGGAGGAATTGTTGTAACAACTGCAGGAATGTTAGATGGAGGGCCTATACTGTAT
TATCTAAAATTATTCATGCATAATCCTAAAAATGCCTTATTATTAACTGGTTACCAAGTTAGAGACTCCAATGGAAGACA
TTTAATTGAAACTGGAAAGATATTTATTGGAAAAGATGAAATTAAGCCAAACTTAGAAGTTTGCATGTATAACTTCTCAT
GCCACGCTGGGATGGATGAGCTACATGAGATAATTAAAAAAGTCAATCCTGAGCTATTAATTATACAACATGGAGAGGAA
GTTCAGGCAACAATTTTAAGAAACTGGGCGTTAGAACATGGATTTGATGCAATAACTCCAAAATTAGGAGAAAAAATAAG
AATCTAA

Upstream 100 bases:

>100_bases
ATCTTTATCAATATATTTGAATATAACAATTAATATTTTATAAAAAGTATTTAATAGCAAAAATAACAGAAATTAAAAAT
TGAATAAAAATGGTGGTATC

Downstream 100 bases:

>100_bases
AGATAAAGAGGAAGAGATATGTTGGGATTAAAGATTGAAGATGCTATAAAATACAATGAAAAATTAAAAAAGTATGTTTA
TAAAAAAGGAGATAAGCTTA

Product: putative mRNA 3'-end processing factor 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MEIIFRGAALEVGRSCIEIKTDKSKILLDCGVKLGKEIEYPILDNSIRDVDKVFISHAHLDHSGALPVLFHRKMDVPVIT
TELSKKLIKVLLKDMVKIAETENKKIPYNNHDVKEAIRHTIPLNYNDKKYYKDFSYELFSAGHIPGSASILLNYQNNKTI
LYTGDVKLRDTRLTKGADLSYTKDDIDILIIESTYGNSIHPDRKAVELSFIEKIKEILFRGGVALIPVFAVDRAQEILLI
LNDYNIDAPIYLDGMAVEVTKLMLNYKHMLNESSQLEKALKNVKIIEKSEDRIKAIENLSKNGGIVVTTAGMLDGGPILY
YLKLFMHNPKNALLLTGYQVRDSNGRHLIETGKIFIGKDEIKPNLEVCMYNFSCHAGMDELHEIIKKVNPELLIIQHGEE
VQATILRNWALEHGFDAITPKLGEKIRI

Sequences:

>Translated_428_residues
MEIIFRGAALEVGRSCIEIKTDKSKILLDCGVKLGKEIEYPILDNSIRDVDKVFISHAHLDHSGALPVLFHRKMDVPVIT
TELSKKLIKVLLKDMVKIAETENKKIPYNNHDVKEAIRHTIPLNYNDKKYYKDFSYELFSAGHIPGSASILLNYQNNKTI
LYTGDVKLRDTRLTKGADLSYTKDDIDILIIESTYGNSIHPDRKAVELSFIEKIKEILFRGGVALIPVFAVDRAQEILLI
LNDYNIDAPIYLDGMAVEVTKLMLNYKHMLNESSQLEKALKNVKIIEKSEDRIKAIENLSKNGGIVVTTAGMLDGGPILY
YLKLFMHNPKNALLLTGYQVRDSNGRHLIETGKIFIGKDEIKPNLEVCMYNFSCHAGMDELHEIIKKVNPELLIIQHGEE
VQATILRNWALEHGFDAITPKLGEKIRI
>Mature_428_residues
MEIIFRGAALEVGRSCIEIKTDKSKILLDCGVKLGKEIEYPILDNSIRDVDKVFISHAHLDHSGALPVLFHRKMDVPVIT
TELSKKLIKVLLKDMVKIAETENKKIPYNNHDVKEAIRHTIPLNYNDKKYYKDFSYELFSAGHIPGSASILLNYQNNKTI
LYTGDVKLRDTRLTKGADLSYTKDDIDILIIESTYGNSIHPDRKAVELSFIEKIKEILFRGGVALIPVFAVDRAQEILLI
LNDYNIDAPIYLDGMAVEVTKLMLNYKHMLNESSQLEKALKNVKIIEKSEDRIKAIENLSKNGGIVVTTAGMLDGGPILY
YLKLFMHNPKNALLLTGYQVRDSNGRHLIETGKIFIGKDEIKPNLEVCMYNFSCHAGMDELHEIIKKVNPELLIIQHGEE
VQATILRNWALEHGFDAITPKLGEKIRI

Specific function: Unknown

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family

Homologues:

Organism=Homo sapiens, GI7706427, Length=422, Percent_Identity=29.6208530805687, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI33300633, Length=426, Percent_Identity=28.4037558685446, Blast_Score=159, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI32566029, Length=409, Percent_Identity=27.3838630806846, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32564696, Length=428, Percent_Identity=28.9719626168224, Blast_Score=155, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6323307, Length=446, Percent_Identity=26.2331838565022, Blast_Score=133, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24648013, Length=425, Percent_Identity=28.4705882352941, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21358523, Length=426, Percent_Identity=29.1079812206573, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y047_METJA (Q60355)

Other databases:

- EMBL:   L77117
- RefSeq:   NP_247010.1
- ProteinModelPortal:   Q60355
- SMR:   Q60355
- GeneID:   1450885
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0047
- NMPDR:   fig|243232.1.peg.47
- TIGR:   MJ0047
- HOGENOM:   HBG402464
- OMA:   WFDFSAH
- ProtClustDB:   CLSK2517541
- BioCyc:   MJAN243232:MJ_0047-MONOMER
- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108
- SMART:   SM00849

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL

EC number: NA

Molecular weight: Translated: 48493; Mature: 48493

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIFRGAALEVGRSCIEIKTDKSKILLDCGVKLGKEIEYPILDNSIRDVDKVFISHAHL
CEEEEECCHHHHCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
DHSGALPVLFHRKMDVPVITTELSKKLIKVLLKDMVKIAETENKKIPYNNHDVKEAIRHT
CCCCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
IPLNYNDKKYYKDFSYELFSAGHIPGSASILLNYQNNKTILYTGDVKLRDTRLTKGADLS
CCCCCCCHHHHHCCCCCEEECCCCCCCEEEEEEECCCEEEEEECCEEEEEEECCCCCCCC
YTKDDIDILIIESTYGNSIHPDRKAVELSFIEKIKEILFRGGVALIPVFAVDRAQEILLI
CCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEE
LNDYNIDAPIYLDGMAVEVTKLMLNYKHMLNESSQLEKALKNVKIIEKSEDRIKAIENLS
EECCCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHHHHHHHCC
KNGGIVVTTAGMLDGGPILYYLKLFMHNPKNALLLTGYQVRDSNGRHLIETGKIFIGKDE
CCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEEECCEEEECCC
IKPNLEVCMYNFSCHAGMDELHEIIKKVNPELLIIQHGEEVQATILRNWALEHGFDAITP
CCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCH
KLGEKIRI
HCCCCCCC
>Mature Secondary Structure
MEIIFRGAALEVGRSCIEIKTDKSKILLDCGVKLGKEIEYPILDNSIRDVDKVFISHAHL
CEEEEECCHHHHCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
DHSGALPVLFHRKMDVPVITTELSKKLIKVLLKDMVKIAETENKKIPYNNHDVKEAIRHT
CCCCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
IPLNYNDKKYYKDFSYELFSAGHIPGSASILLNYQNNKTILYTGDVKLRDTRLTKGADLS
CCCCCCCHHHHHCCCCCEEECCCCCCCEEEEEEECCCEEEEEECCEEEEEEECCCCCCCC
YTKDDIDILIIESTYGNSIHPDRKAVELSFIEKIKEILFRGGVALIPVFAVDRAQEILLI
CCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEE
LNDYNIDAPIYLDGMAVEVTKLMLNYKHMLNESSQLEKALKNVKIIEKSEDRIKAIENLS
EECCCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHHHHHHHCC
KNGGIVVTTAGMLDGGPILYYLKLFMHNPKNALLLTGYQVRDSNGRHLIETGKIFIGKDE
CCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEEECCEEEECCC
IKPNLEVCMYNFSCHAGMDELHEIIKKVNPELLIIQHGEEVQATILRNWALEHGFDAITP
CCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCH
KLGEKIRI
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087