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Identifier: 15646100

GI number: 15646100

Start: 1564521

End: 1566122

Strand: Reverse

Name: Not Available

Synonym: HP1491

Alternate gene names: 15646100

Gene position: 1566122-1564521 (Counterclockwise)

Preceding gene: 15646109

Following gene: 15646099

Centisome position: 93.9

GC content: 43.07

Gene sequence:

>1602_bases
ATGGAAATTAAAAACATCAAAGAGTTTGAAAAAGCTTCCAAAAAACTCCAAAAAGACACTTTAAAGATCGCTCTCGCTCT
TTTGTTTCTCATCGGTGCCGCTTTACTCGCTCTCATTTTTGGGCAGGCTAATTCTAAGGGATTGTTGCTTATTTTTGCGG
CCGTGATTGGGGGGTATATGGCGATGAATATTGGCGCGAATGATGTGTCTAATAATGTCGGCCCTGCCGTAGGCTCTAAA
GCCATTAGCATGGGCGGGGCGATTTTGATCGCTGCGATTTGCGAAATGCTTGGAGCGATCATTGCTGGGGGGGAAGTGGT
TTCTACGATTAAGGGCCGTATCGTTTCGCCTGAATTTATTAATGATGCGCACATTTTCATTAATGTCATGTTGGCTAGCT
TACTCAGTGGGGCGTTGTGGTTGCATGTAGCGACTTTAATTGGCGCTCCCGTTTCCACTTCACACTCTGTGGTGGGGGGG
ATTATGGGGGCTGGAATGGCAGCAGCTGGAATGGTAGCTGTCAATTGGCATTTTTTATCCGGTATTGTGGCCAGTTGGGT
AATTTCGCCTTTAATGGGGGCTTTGATAGCCATGTTTTTTTTAATGCTCATTAAAAAGACTATCGCTTATAAAGAAGATA
AAAAGAGTGCGGCTTTAAAGGTCGTGCCTTATTTGGTAGCGTTGATGAGCTTAACATTCAGCTGGTATTTGATTGTTAAG
GTTTTAAAACGCCTCTATGCATTGAATTTTGAAATCCAGTTGGCTTGTGGCTGTATCCTTGCGCTTTTAATCTTTATCCT
TTTTAAAAGATTTGTGTTAAAGAAAGCCCCGCAATTAGAAAACAGCCATGAAAGCATTAATGAGCTTTTCAATGTCCCTT
TGATTTTTGCCGCTGCACTTTTAAGCTTTGCGCATGGGGCTAATGATGTGGCTAACGCTATAGGCCCCTTAGCCGCAATC
AGTCAAACTTTAGAAGATGCAAATAGCCCTATAGGGAATACTTTAAGCTCTGTGCCGTTGTGGATTATGGTAGTAGGGGC
GGCTGGGATTGCTTTAGGCTTGAGTTTGTATGGGCCAAAGCTCATTAAAACGGTGGGGTCAGAAATCACAGAATTAGACA
AGATGCAAGCTTTTTGCATCGCGCTTTCAGCAGTCATCACCGTGCTTTTAGCCTCTCAATTAGGCTTGCCCGTAAGCTCT
ACGCATATTGTGGTGGGCGCGGTGTTTGGGGTGGGCTTTTTAAGGGAGCGCTTAAGAGAGCAATCAAGAAGGCGTTTTGC
TAGAATCAGAGACAACATTGTAGCCGCGCACTTTGGGGAAGATTTAGAAGAAATTGAAGGCTTTTTAGAGCGCTTTGATA
AAGCCAATTTGAAAGAAAAATCGCTCATGCTAGAGAGCTTAAAAAAAAGCAAGAACACCGCCATCGCTTTGGAATTGAAA
AAGAAAGAAAAAAAGTCGCTTAAAAAAGTGTATAAAGAAGAAGTGATCAAACGCTCCATTTTAAAAAAGATTGTTACCGC
TTGGTTGGTAACCGTGCCGGTTTCTGCGCTTTTGGGGGCGCTTCTGTTTGTGGCTCTTGGTTTTATAGAAAAGTATTTCT
AG

Upstream 100 bases:

>100_bases
ATATAATGAGCCATTTTTATCAAACAACGCTTTTTAAGAGTGGCTCAAGGGCTAATTGGATAGAATAAGACCACTATTAG
AACAAGGTTTTTATGACGAT

Downstream 100 bases:

>100_bases
GGTTTTTGAAGGCTTGATTTTTAAAGTTAGGCTTAATCTTTTATGTTAAAATTCTGAGATTTTATATATTTTATATTTAT
CGTTAGGTTTTAGGTTTAAA

Product: phosphate permease

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYMAMNIGANDVSNNVGPAVGSK
AISMGGAILIAAICEMLGAIIAGGEVVSTIKGRIVSPEFINDAHIFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGG
IMGAGMAAAGMVAVNWHFLSGIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLTFSWYLIVK
VLKRLYALNFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNVPLIFAAALLSFAHGANDVANAIGPLAAI
SQTLEDANSPIGNTLSSVPLWIMVVGAAGIALGLSLYGPKLIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSS
THIVVGAVFGVGFLRERLREQSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF

Sequences:

>Translated_533_residues
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYMAMNIGANDVSNNVGPAVGSK
AISMGGAILIAAICEMLGAIIAGGEVVSTIKGRIVSPEFINDAHIFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGG
IMGAGMAAAGMVAVNWHFLSGIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLTFSWYLIVK
VLKRLYALNFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNVPLIFAAALLSFAHGANDVANAIGPLAAI
SQTLEDANSPIGNTLSSVPLWIMVVGAAGIALGLSLYGPKLIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSS
THIVVGAVFGVGFLRERLREQSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF
>Mature_533_residues
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYMAMNIGANDVSNNVGPAVGSK
AISMGGAILIAAICEMLGAIIAGGEVVSTIKGRIVSPEFINDAHIFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGG
IMGAGMAAAGMVAVNWHFLSGIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLTFSWYLIVK
VLKRLYALNFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNVPLIFAAALLSFAHGANDVANAIGPLAAI
SQTLEDANSPIGNTLSSVPLWIMVVGAAGIALGLSLYGPKLIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSS
THIVVGAVFGVGFLRERLREQSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF

Specific function: Potential transporter for phosphate

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family

Homologues:

Organism=Homo sapiens, GI31543630, Length=140, Percent_Identity=37.8571428571429, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI5803173, Length=132, Percent_Identity=38.6363636363636, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71981576, Length=424, Percent_Identity=31.8396226415094, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17557328, Length=482, Percent_Identity=25.7261410788382, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI25146401, Length=154, Percent_Identity=37.6623376623377, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17539280, Length=272, Percent_Identity=30.1470588235294, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32566716, Length=180, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17536725, Length=148, Percent_Identity=28.3783783783784, Blast_Score=82, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319773, Length=142, Percent_Identity=36.6197183098592, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI21356511, Length=253, Percent_Identity=30.4347826086957, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1491_HELPY (O26024)

Other databases:

- EMBL:   AE000511
- PIR:   C64706
- RefSeq:   NP_208282.1
- GeneID:   899801
- GenomeReviews:   AE000511_GR
- KEGG:   hpy:HP1491
- NMPDR:   fig|85962.1.peg.1478
- TIGR:   HP_1491
- HOGENOM:   HBG681698
- OMA:   KLNPMRA
- ProtClustDB:   CLSK551913
- InterPro:   IPR001204
- PANTHER:   PTHR11101

Pfam domain/function: PF01384 PHO4

EC number: NA

Molecular weight: Translated: 57277; Mature: 57277

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xebb8868)-; HASH(0xecca038)-; HASH(0xdc22204)-; HASH(0xead6b5c)-; HASH(0xec96c70)-; HASH(0xe53afb4)-; HASH(0xec898a0)-; HASH(0xebc9344)-; HASH(0xb2ca018)-; HASH(0xdbd4e68)-; HASH(0xe2d0c50)-; HASH(0xe337d10)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AMNIGANDVSNNVGPAVGSKAISMGGAILIAAICEMLGAIIAGGEVVSTIKGRIVSPEFI
EEECCCHHHCCCCCCHHCHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHH
NDAHIFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGGIMGAGMAAAGMVAVNWHFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLTFSWYLIVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKRLYALNFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNVPLIFAAAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHH
LSFAHGANDVANAIGPLAAISQTLEDANSPIGNTLSSVPLWIMVVGAAGIALGLSLYGPK
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHH
LIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSSTHIVVGAVFGVGFLRERLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
QSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEH
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AMNIGANDVSNNVGPAVGSKAISMGGAILIAAICEMLGAIIAGGEVVSTIKGRIVSPEFI
EEECCCHHHCCCCCCHHCHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHH
NDAHIFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGGIMGAGMAAAGMVAVNWHFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLTFSWYLIVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKRLYALNFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNVPLIFAAAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHH
LSFAHGANDVANAIGPLAAISQTLEDANSPIGNTLSSVPLWIMVVGAAGIALGLSLYGPK
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHH
LIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSSTHIVVGAVFGVGFLRERLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
QSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEH
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185