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Identifier: 15646081

GI number: 15646081

Start: 1544702

End: 1546741

Strand: Reverse

Name: Not Available

Synonym: HP1472

Alternate gene names: 15646081

Gene position: 1546741-1544702 (Counterclockwise)

Preceding gene: 15646082

Following gene: 15646080

Centisome position: 92.74

GC content: 38.73

Gene sequence:

>2040_bases
ATGAATAAAGTTCAATCTATTGATCCTTTAATCGCTGATAAGTTCAACAACGAGTTAAGAAGTTATAACCTAGAATACAA
ACTAGAGCAAGAAAGCCTGAATAAAGAAATTGATGAAGCTTTAAAAAATTACGCTTCTAAAAATGGGGGTTTAGGGGGTA
ACCGCCCTGATGTGAAACTTTTATTAAACACACAAGACCCCAACAGAAGAGTCCCTATTTTAATAGAATACAAAGGGCTA
AAAGATAAGCTCATTAAATTAGACAAAAACAAACTGGTAGAAAACTTTAAAAACCATGAGCCTCATTATAAAAACATTAG
AGAATACGCCCTAAATGGGGCTTTGCATTACGCTAATGCGATTTTACACCACACGAGCTACACTGAATGCATCGCCATAG
GCATTACAGGCTATAAAGACAATAAGGGCGGCATATGCTCTCAAATCGCTGTCTATTATGTGAATAAAAGCAATCTAGGC
ATGGGGATAGATGTTTCAAAAGGCGAGCAAGGTTATAGCGATCTCTCCTTTTTAAGCCGTAAGCATTTTAACGACTTTAT
TAAACGAGTAGACACCCTTTCTTTAAGCGATGAAGATTTAGAGCGCATTAGAGAAAAGAAAAACCAAGAAATAGAAGACT
GCTTAATGCGGCTCAACAACAATATTTACAACAAAGAAAAGAATTTTTTAAGCGAACACAATCGGGTATATTTAGTGATT
GCGAGCATTATCGCTAATTTAGGCATCCCTAATTTGGTAACCCCCCTAAACAAAGAAGATCTAAAATCCAGCGATGAGGT
CCATCAAAGAGATGGCGACATCATGCTCAGAAAAATCCAATCCTTTTTAGAGAATAAGGATTTGTCTCCAGAGAAAAGGC
AAAGCATTATTTCTTCATTAGAGACTTTATTAAGAAACGAAAACAACAACAAAGCCACTAATGGCGAAAGCTGTTTGAAG
CGTTGTTTTAGTGAGATTGTGGATAGTTTGGGCATTTATTATAAAATCGGTCTTAGCACGGATTTTACCGGTAAATTGTT
CAATGAAATGTATCGCTGGCTGGGTTTCACGAAAGACCAATTAAACGATGTGGTGCTCACACCCCCTTATGTCGCCACGC
TTTTAGCTAGACTTTCTAAAGTCAATAAGGATAGTTTCGTGTGGGATTTTGCCACCGGAAGCGCTGGGCTATTAGTCGCA
AGCATGAATTTGATGATAGAAGACGCTAAAAAGCGTATCACTAGTCCAGAGGAATTAGAGCAAAAAATCGCCCACATTAA
AGCCAAGCAACTTTTAGGGATAGAAATCTTATCGGATATCCATACTTTAGCGGTGTTAAACATGATTTTAATGGGCGATG
GGAGCAGTCAAATCTTAAACCAAGACGGCTTGAGCGGTTTTGATGGCAAAGTCAATAACGAAGCGTTTAAGGCTAATGCC
TTTGTTTTAAACCCGCCTTATTCCGCTAGCGGTAATGGCATGGTGTTTGTGGAGCAGGCTTTAGAAAAAATGCAAAGCGG
TTATGCGAGCGTGATCATCCAATCAAGCGCCGGCAGTGGTAAAGCCAAAGAATACAATGTAAGGATTTTGGAAAAACACA
CGCTTTTAGCGAGCATTAAAATGCCTTTAGATTTATTCATCGGTAAAAGCAGCGTTCAAACCCATATCTATGTTTTTAGG
GTCAATGAAAAGCATGACGCTAAGCAAAGGGTGAAATTTATTAATTTCAGTAACGACGGCTACGCTAGAGCGAATCGCAA
AAAAGCCAAAGCCAGCCACAATTTAAAAGACACGCATAACGCCAAAGAGCGCTACAACGAAGTCGTGGATTTAGTCCATA
TTGGCCAATCATGTTTGAAATTTCTAAGCGAAGATGACTATTATGAAAACACCATAGATCCCAAAAACGGGAGCGATTGG
AACCAAAACAAACCCACTGACACCAAACCCGAATTAGAGGATTTTAAAAGAACGATAGCCGATTACCTTTCTTATGAAGT
AAGCTTGATTTTAAAAAACCAAATGCCCCCAAAGCGATAG

Upstream 100 bases:

>100_bases
CCTAAAATACCTTAAAACCCTAAACATAAAAGTACACTTTGCGATCGCGCTTTGCAGCGCGGATGAATGAGTTATAATTT
TATTTTTTAAAAGGATACCC

Downstream 100 bases:

>100_bases
GCCCCCTTAATAGCCAACTCAACGCTATTAAGTGGGGCGAGTTCAGATTGGGGGATTTGTTTGAAGTGTTGTCAAGTAAG
AAAATTTATCATGCCAACAC

Product: type IIS restriction enzyme M protein (mod)

Products: NA

Alternate protein names: Adenine-specific methyltransferase activity [H]

Number of amino acids: Translated: 679; Mature: 679

Protein sequence:

>679_residues
MNKVQSIDPLIADKFNNELRSYNLEYKLEQESLNKEIDEALKNYASKNGGLGGNRPDVKLLLNTQDPNRRVPILIEYKGL
KDKLIKLDKNKLVENFKNHEPHYKNIREYALNGALHYANAILHHTSYTECIAIGITGYKDNKGGICSQIAVYYVNKSNLG
MGIDVSKGEQGYSDLSFLSRKHFNDFIKRVDTLSLSDEDLERIREKKNQEIEDCLMRLNNNIYNKEKNFLSEHNRVYLVI
ASIIANLGIPNLVTPLNKEDLKSSDEVHQRDGDIMLRKIQSFLENKDLSPEKRQSIISSLETLLRNENNNKATNGESCLK
RCFSEIVDSLGIYYKIGLSTDFTGKLFNEMYRWLGFTKDQLNDVVLTPPYVATLLARLSKVNKDSFVWDFATGSAGLLVA
SMNLMIEDAKKRITSPEELEQKIAHIKAKQLLGIEILSDIHTLAVLNMILMGDGSSQILNQDGLSGFDGKVNNEAFKANA
FVLNPPYSASGNGMVFVEQALEKMQSGYASVIIQSSAGSGKAKEYNVRILEKHTLLASIKMPLDLFIGKSSVQTHIYVFR
VNEKHDAKQRVKFINFSNDGYARANRKKAKASHNLKDTHNAKERYNEVVDLVHIGQSCLKFLSEDDYYENTIDPKNGSDW
NQNKPTDTKPELEDFKRTIADYLSYEVSLILKNQMPPKR

Sequences:

>Translated_679_residues
MNKVQSIDPLIADKFNNELRSYNLEYKLEQESLNKEIDEALKNYASKNGGLGGNRPDVKLLLNTQDPNRRVPILIEYKGL
KDKLIKLDKNKLVENFKNHEPHYKNIREYALNGALHYANAILHHTSYTECIAIGITGYKDNKGGICSQIAVYYVNKSNLG
MGIDVSKGEQGYSDLSFLSRKHFNDFIKRVDTLSLSDEDLERIREKKNQEIEDCLMRLNNNIYNKEKNFLSEHNRVYLVI
ASIIANLGIPNLVTPLNKEDLKSSDEVHQRDGDIMLRKIQSFLENKDLSPEKRQSIISSLETLLRNENNNKATNGESCLK
RCFSEIVDSLGIYYKIGLSTDFTGKLFNEMYRWLGFTKDQLNDVVLTPPYVATLLARLSKVNKDSFVWDFATGSAGLLVA
SMNLMIEDAKKRITSPEELEQKIAHIKAKQLLGIEILSDIHTLAVLNMILMGDGSSQILNQDGLSGFDGKVNNEAFKANA
FVLNPPYSASGNGMVFVEQALEKMQSGYASVIIQSSAGSGKAKEYNVRILEKHTLLASIKMPLDLFIGKSSVQTHIYVFR
VNEKHDAKQRVKFINFSNDGYARANRKKAKASHNLKDTHNAKERYNEVVDLVHIGQSCLKFLSEDDYYENTIDPKNGSDW
NQNKPTDTKPELEDFKRTIADYLSYEVSLILKNQMPPKR
>Mature_679_residues
MNKVQSIDPLIADKFNNELRSYNLEYKLEQESLNKEIDEALKNYASKNGGLGGNRPDVKLLLNTQDPNRRVPILIEYKGL
KDKLIKLDKNKLVENFKNHEPHYKNIREYALNGALHYANAILHHTSYTECIAIGITGYKDNKGGICSQIAVYYVNKSNLG
MGIDVSKGEQGYSDLSFLSRKHFNDFIKRVDTLSLSDEDLERIREKKNQEIEDCLMRLNNNIYNKEKNFLSEHNRVYLVI
ASIIANLGIPNLVTPLNKEDLKSSDEVHQRDGDIMLRKIQSFLENKDLSPEKRQSIISSLETLLRNENNNKATNGESCLK
RCFSEIVDSLGIYYKIGLSTDFTGKLFNEMYRWLGFTKDQLNDVVLTPPYVATLLARLSKVNKDSFVWDFATGSAGLLVA
SMNLMIEDAKKRITSPEELEQKIAHIKAKQLLGIEILSDIHTLAVLNMILMGDGSSQILNQDGLSGFDGKVNNEAFKANA
FVLNPPYSASGNGMVFVEQALEKMQSGYASVIIQSSAGSGKAKEYNVRILEKHTLLASIKMPLDLFIGKSSVQTHIYVFR
VNEKHDAKQRVKFINFSNDGYARANRKKAKASHNLKDTHNAKERYNEVVDLVHIGQSCLKFLSEDDYYENTIDPKNGSDW
NQNKPTDTKPELEDFKRTIADYLSYEVSLILKNQMPPKR

Specific function: Recognizes the double-stranded sequence 5'-CGAN(6)TGC-3' and cleaves bilaterally and symmetrically outside the sequence to release a 34-base pair fragment. Methylation of the recognition sequence occurs on the adenine in either one or both strands [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 77051; Mature: 77051

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVQSIDPLIADKFNNELRSYNLEYKLEQESLNKEIDEALKNYASKNGGLGGNRPDVKL
CCCCCCCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
LLNTQDPNRRVPILIEYKGLKDKLIKLDKNKLVENFKNHEPHYKNIREYALNGALHYANA
EEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ILHHTSYTECIAIGITGYKDNKGGICSQIAVYYVNKSNLGMGIDVSKGEQGYSDLSFLSR
HHHCCCCCEEEEEEEECCCCCCCCHHEEEEEEEEECCCCCCCEECCCCCCCCHHHHHHHH
KHFNDFIKRVDTLSLSDEDLERIREKKNQEIEDCLMRLNNNIYNKEKNFLSEHNRVYLVI
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCEEEEEH
ASIIANLGIPNLVTPLNKEDLKSSDEVHQRDGDIMLRKIQSFLENKDLSPEKRQSIISSL
HHHHHHCCCCHHCCCCCHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ETLLRNENNNKATNGESCLKRCFSEIVDSLGIYYKIGLSTDFTGKLFNEMYRWLGFTKDQ
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHH
LNDVVLTPPYVATLLARLSKVNKDSFVWDFATGSAGLLVASMNLMIEDAKKRITSPEELE
CCCEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
QKIAHIKAKQLLGIEILSDIHTLAVLNMILMGDGSSQILNQDGLSGFDGKVNNEAFKANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCEEECCE
FVLNPPYSASGNGMVFVEQALEKMQSGYASVIIQSSAGSGKAKEYNVRILEKHTLLASIK
EEECCCCCCCCCCEEEHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEEHHHHHHHHC
MPLDLFIGKSSVQTHIYVFRVNEKHDAKQRVKFINFSNDGYARANRKKAKASHNLKDTHN
CCHHHEECCCCCEEEEEEEEECCCCCHHHHEEEEEECCCCCCCCCHHHHHHCCCCCHHHH
AKERYNEVVDLVHIGQSCLKFLSEDDYYENTIDPKNGSDWNQNKPTDTKPELEDFKRTIA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
DYLSYEVSLILKNQMPPKR
HHHHHHHHEEEECCCCCCC
>Mature Secondary Structure
MNKVQSIDPLIADKFNNELRSYNLEYKLEQESLNKEIDEALKNYASKNGGLGGNRPDVKL
CCCCCCCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
LLNTQDPNRRVPILIEYKGLKDKLIKLDKNKLVENFKNHEPHYKNIREYALNGALHYANA
EEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ILHHTSYTECIAIGITGYKDNKGGICSQIAVYYVNKSNLGMGIDVSKGEQGYSDLSFLSR
HHHCCCCCEEEEEEEECCCCCCCCHHEEEEEEEEECCCCCCCEECCCCCCCCHHHHHHHH
KHFNDFIKRVDTLSLSDEDLERIREKKNQEIEDCLMRLNNNIYNKEKNFLSEHNRVYLVI
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCEEEEEH
ASIIANLGIPNLVTPLNKEDLKSSDEVHQRDGDIMLRKIQSFLENKDLSPEKRQSIISSL
HHHHHHCCCCHHCCCCCHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ETLLRNENNNKATNGESCLKRCFSEIVDSLGIYYKIGLSTDFTGKLFNEMYRWLGFTKDQ
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHH
LNDVVLTPPYVATLLARLSKVNKDSFVWDFATGSAGLLVASMNLMIEDAKKRITSPEELE
CCCEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
QKIAHIKAKQLLGIEILSDIHTLAVLNMILMGDGSSQILNQDGLSGFDGKVNNEAFKANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCEEECCE
FVLNPPYSASGNGMVFVEQALEKMQSGYASVIIQSSAGSGKAKEYNVRILEKHTLLASIK
EEECCCCCCCCCCEEEHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEEHHHHHHHHC
MPLDLFIGKSSVQTHIYVFRVNEKHDAKQRVKFINFSNDGYARANRKKAKASHNLKDTHN
CCHHHEECCCCCEEEEEEEEECCCCCHHHHEEEEEECCCCCCCCCHHHHHHCCCCCHHHH
AKERYNEVVDLVHIGQSCLKFLSEDDYYENTIDPKNGSDWNQNKPTDTKPELEDFKRTIA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
DYLSYEVSLILKNQMPPKR
HHHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8451198; 8276869 [H]