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Identifier: 15646067

GI number: 15646067

Start: 1527772

End: 1528086

Strand: Reverse

Name: Not Available

Synonym: HP1458

Alternate gene names: 15646067

Gene position: 1528086-1527772 (Counterclockwise)

Preceding gene: 15646068

Following gene: 15646066

Centisome position: 91.62

GC content: 42.86

Gene sequence:

>315_bases
ATGTCAGAAATGATTAACGGGAAGAATTACGCAGAGAAAATCGCTCATCAAGCGGTGGTGGTTAATGTGGGGGCGAGCTG
GTGCCCGGATTGCAGAAAGATTGAGCCGATCATGGAAAATTTAGCCAAAACTTACAAAGGCAAGGTGGAATTTTTTAAGG
TTTCTTTTGATGAGAGCCAGGATCTCAAAGAGAGCTTAGGCATCCGCAAGATCCCTACTTTGATTTTTTACAAAAACGCC
AAAGAAGTGGGGGAAAGGCTTGTAGAACCTAGCTCTCAAAAACCGATTGAAGACGCTCTAAAAGCGTTATTGTAA

Upstream 100 bases:

>100_bases
GTTGCATGCGTTTATGGCTAATGCGGCTAATGTTAAAGGGGATTAGCTTACGAGTTATGCTATACTTCAAAGTTGGGGGA
AATAAAAAATAAGGATTATC

Downstream 100 bases:

>100_bases
GGGGTATCATAAAGGGCGTTATTAAAGAGCCTTATTGTAAAAATAAGAGTTCACAGAATCTTTTTAGCCCCTTTTTTTAT
AAAGGGGCTAACTTCAAATA

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MSEMINGKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNA
KEVGERLVEPSSQKPIEDALKALL

Sequences:

>Translated_104_residues
MSEMINGKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNA
KEVGERLVEPSSQKPIEDALKALL
>Mature_103_residues
SEMINGKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNAK
EVGERLVEPSSQKPIEDALKALL

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788936, Length=65, Percent_Identity=41.5384615384615, Blast_Score=62, Evalue=6e-12,
Organism=Escherichia coli, GI87082331, Length=90, Percent_Identity=35.5555555555556, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 11745; Mature: 11614

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEMINGKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQ
CCCCCCCHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCH
DLKESLGIRKIPTLIFYKNAKEVGERLVEPSSQKPIEDALKALL
HHHHHCCCCCCCHHHEECCHHHHHHHHCCCCCCCCHHHHHHHHC
>Mature Secondary Structure 
SEMINGKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKGKVEFFKVSFDESQ
CCCCCCHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCH
DLKESLGIRKIPTLIFYKNAKEVGERLVEPSSQKPIEDALKALL
HHHHHCCCCCCCHHHEECCHHHHHHHHCCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA