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Identifier: 15645959

GI number: 15645959

Start: 1406099

End: 1407091

Strand: Reverse

Name: Not Available

Synonym: HP1346

Alternate gene names: 15645959

Gene position: 1407091-1406099 (Counterclockwise)

Preceding gene: 15645960

Following gene: 15645958

Centisome position: 84.36

GC content: 42.09

Gene sequence:

>993_bases
ATGCCAATTAGAATCGCTATCAATGGGACTGGGCGCATCGGTTTGTGCGCTATAAGAGTCGCTAGTCAAAGAAAGGATAT
AGAAATTGTCGCTATCAATTCTACCGCTGAATTAGAAACTCTTTTGCATTTGATCCGCCATGACAGCGTGCATGGGCATT
TTGAAGCCCAATTAAACGCTGATAGAACCCTAAATATCGGGCATAGTAAAAACATTTTAGTGTTGAGCGAGCGAGACATC
AACAAGCTTGATTTTTCTGCCGCTAACGCAGAAATCATCATAGAATGCACCGGGAAATTCAATTCCCTAGAAGCTTCAAG
CGCTCATCTTAAAAACAGCGTGAAAAAAGTCATCATCTCCGCTCCCGCACAAAATACGCCCACCTTTGTCTATGGGGTGA
ATCATAAGAATTACCATAATGAAAGCGTGATTTCTAACGCTTCTTGCACGACTAATGCTAGCGCTCCTTTATTAAAAATC
TTAGATGAAGCCTTTAAAGTAGAAAACGCGCTTTTAACCACCATTCACAGCTACACTAACGATCAAAACCTTTTAGACAC
CAAGCACAAAGACATCCGCCGCGCTAGAGCGGCTGGTTTAAACCTTATCCCCACAAGCACCGGCGTGAGCAAAGCCATTT
CGCTAGTCTTACCGCATTTAGGCCCTAAAGTTACAGGCCTTGCGATTAGAGTGCCTACCCCCAATGTGAGCTTAGTGGAT
CTGTCTTTAAATTTTAAAAAATCCGTGAGTAAAGCAAGCGTTCAGCATGCGCTTAAAGACGCTTGTAAGCATGCCTTTAA
AGGGGTTGTAAGCATTGATGAAGAAAGGCTTGTTTCAAGCGATTTTATTTCTTCGCCTTTTAGCGCGATCGTGATTGATG
ATCAAATCATGACAATAGGCGAAAAAAATGCTAAAGTATTGGCATGGTATGATAATGAGATGGGTTATAGCGAGCGCTTG
ATAGACATGGCGCAATATATAGCACAAAATTAA

Upstream 100 bases:

>100_bases
TTTAGTTTATGATTGATGCTTAATGAGACAGAACCCCTTAAGAATGCCTTTATTTAAGAGCATTTGTGATAGAATGGTGA
TTTTTAAATAAAGGGAAAAC

Downstream 100 bases:

>100_bases
AAGAAAGGATTTTTCATGTTAGCTAAAATGTCGTTTATGCAAAATGTTAAAAACATTCAAGAAGTGGAAGTGAGCCATAA
AAGGGTGCTTATTAGAGTGG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPIRIAINGTGRIGLCAIRVASQRKDIEIVAINSTAELETLLHLIRHDSVHGHFEAQLNADRTLNIGHSKNILVLSERDI
NKLDFSAANAEIIIECTGKFNSLEASSAHLKNSVKKVIISAPAQNTPTFVYGVNHKNYHNESVISNASCTTNASAPLLKI
LDEAFKVENALLTTIHSYTNDQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGPKVTGLAIRVPTPNVSLVD
LSLNFKKSVSKASVQHALKDACKHAFKGVVSIDEERLVSSDFISSPFSAIVIDDQIMTIGEKNAKVLAWYDNEMGYSERL
IDMAQYIAQN

Sequences:

>Translated_330_residues
MPIRIAINGTGRIGLCAIRVASQRKDIEIVAINSTAELETLLHLIRHDSVHGHFEAQLNADRTLNIGHSKNILVLSERDI
NKLDFSAANAEIIIECTGKFNSLEASSAHLKNSVKKVIISAPAQNTPTFVYGVNHKNYHNESVISNASCTTNASAPLLKI
LDEAFKVENALLTTIHSYTNDQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGPKVTGLAIRVPTPNVSLVD
LSLNFKKSVSKASVQHALKDACKHAFKGVVSIDEERLVSSDFISSPFSAIVIDDQIMTIGEKNAKVLAWYDNEMGYSERL
IDMAQYIAQN
>Mature_329_residues
PIRIAINGTGRIGLCAIRVASQRKDIEIVAINSTAELETLLHLIRHDSVHGHFEAQLNADRTLNIGHSKNILVLSERDIN
KLDFSAANAEIIIECTGKFNSLEASSAHLKNSVKKVIISAPAQNTPTFVYGVNHKNYHNESVISNASCTTNASAPLLKIL
DEAFKVENALLTTIHSYTNDQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGPKVTGLAIRVPTPNVSLVDL
SLNFKKSVSKASVQHALKDACKHAFKGVVSIDEERLVSSDFISSPFSAIVIDDQIMTIGEKNAKVLAWYDNEMGYSERLI
DMAQYIAQN

Specific function: More active in anabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=329, Percent_Identity=38.2978723404255, Blast_Score=251, Evalue=9e-67,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=35.5623100303951, Blast_Score=234, Evalue=6e-62,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=38.368580060423, Blast_Score=259, Evalue=1e-70,
Organism=Escherichia coli, GI1789295, Length=328, Percent_Identity=38.719512195122, Blast_Score=239, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=39.039039039039, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=38.7387387387387, Blast_Score=260, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=39.3393393393393, Blast_Score=256, Evalue=9e-69,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=39.3393393393393, Blast_Score=256, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=40.6060606060606, Blast_Score=267, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=39.6969696969697, Blast_Score=260, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=39.3939393939394, Blast_Score=260, Evalue=2e-70,
Organism=Drosophila melanogaster, GI17933600, Length=327, Percent_Identity=39.7553516819572, Blast_Score=257, Evalue=6e-69,
Organism=Drosophila melanogaster, GI18110149, Length=327, Percent_Identity=39.7553516819572, Blast_Score=257, Evalue=6e-69,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=39.6923076923077, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=39.1437308868502, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=39.1437308868502, Blast_Score=256, Evalue=1e-68,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 36022; Mature: 35890

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRIAINGTGRIGLCAIRVASQRKDIEIVAINSTAELETLLHLIRHDSVHGHFEAQLNA
CCEEEEECCCCCEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECC
DRTLNIGHSKNILVLSERDINKLDFSAANAEIIIECTGKFNSLEASSAHLKNSVKKVIIS
CCEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHEEEEE
APAQNTPTFVYGVNHKNYHNESVISNASCTTNASAPLLKILDEAFKVENALLTTIHSYTN
CCCCCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGPKVTGLAIRVPTPNVSLVD
CCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEE
LSLNFKKSVSKASVQHALKDACKHAFKGVVSIDEERLVSSDFISSPFSAIVIDDQIMTIG
EEECHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHCCCCEEEEECCEEEEEC
EKNAKVLAWYDNEMGYSERLIDMAQYIAQN
CCCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PIRIAINGTGRIGLCAIRVASQRKDIEIVAINSTAELETLLHLIRHDSVHGHFEAQLNA
CEEEEECCCCCEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECC
DRTLNIGHSKNILVLSERDINKLDFSAANAEIIIECTGKFNSLEASSAHLKNSVKKVIIS
CCEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHEEEEE
APAQNTPTFVYGVNHKNYHNESVISNASCTTNASAPLLKILDEAFKVENALLTTIHSYTN
CCCCCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DQNLLDTKHKDIRRARAAGLNLIPTSTGVSKAISLVLPHLGPKVTGLAIRVPTPNVSLVD
CCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEE
LSLNFKKSVSKASVQHALKDACKHAFKGVVSIDEERLVSSDFISSPFSAIVIDDQIMTIG
EEECHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHCCCCEEEEECCEEEEEC
EKNAKVLAWYDNEMGYSERLIDMAQYIAQN
CCCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10799476 [H]