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Identifier: 15645812

GI number: 15645812

Start: 1268377

End: 1277049

Strand: Reverse

Name: Not Available

Synonym: HP1198

Alternate gene names: 15645812

Gene position: 1277049-1268377 (Counterclockwise)

Preceding gene: 15645813

Following gene: 15645811

Centisome position: 76.57

GC content: 43.54

Gene sequence:

>8673_bases
ATGTCAAAAAAAATTCCCCTAAAAAACCGCTTGAGAGCTGATTTTACAAAAACCCCAACAGATTTAGAAGTCCCTAATTT
ATTATTATTACAACGAGACAGCTATGATTCTTTCTTGTATTCTAAAGAGGGTAAAGAGAGCGGGATTGAAAAGGTTTTTA
AATCCATTTTCCCTATCCAAGATGAGCATAACCGCATCACTTTAGAATACGCGGGTTGCGAATTTGGCAAGTCTAAATAC
ACCGTTAGAGAAGCGATGGAGAGGGGCATTACCTACTCTATCCCTCTCAAAATTAAGGTGCGCTTGATCTTGTGGGAAAA
AGATACCAAGAGTGGCGAAAAGAACGGCATTAAGGATATTAAAGAACAAAGCATTTTCATTCGTGAGATCCCTTTGATGA
CAGAACGCACTTCATTTATTATTAATGGGGTGGAGCGCGTGGTGGTCAATCAACTCCACAGAAGCCCCGGTGTGATTTTC
AAAGAAGAAGAGTCTAGCACTTCTTTAAACAAGCTCATTTACACAGGGCAAATCATTCCTGATAGGGGTTCGTGGTTGTA
TTTTGAATACGATTCTAAAGATGTTTTATACGCTCGTATCAATAAACGCCGTAAAGTGCCTGTTACCATTTTATTCAGGG
CGATGGATTATCAAAAACAAGACATCATCAAAATGTTCTACCCGCTTGTTAAAGTGCGTTATGAAAACGATAAATATTTG
ATCCCGTTTGCTTCATTAGACGCCAATCAAAGAATGGAATTTGACTTGAAAGATCCTCAAGGCAAGGTTATTCTTTTAGC
GGGTAAAAAGCTCACTTCAAGAAAGATTAAAGAGCTTAAAGAAAACCATTTAGAATGGGTGGAATACCCTATGGATATTT
TACTCAATCGCCATTTAGCTGAGCCTGTTATGGTAGGGAAAGAAGTCTTATTGGACATGCTCACTCAGCTAGATAAAAAC
AAATTAGAAAAAATCCACGATTTAGGCGTGCAAGAATTTGTGATCATCAACGATCTGGCGTTAGGGCATGACGCTTCCAT
TATCCAATCTTTTTCAGCCGATTCTGAGTCTTTGAAATTACTCAAGCAAACCGAAAAAATTGATGATGAAAACGCTCTAG
CGGCGATTCGTATCCATAAGGTTATGAAACCAGGCGATCCCGTTACGACTGAAGTGGCTAAGCAGTTTGTCAAAAAACTT
TTCTTTGATCCAGAACGCTATGATTTGACCATGGTGGGCCGCATGAAAATGAATCACAAGTTAGGCTTGCATGTGCCTGA
TTACATTACGACTTTAACGCATGAAGATATTATCACCACCGTTAAATACCTCATGAAGATCAAAAACAATCAAGGCAAGA
TTGATGACAGGGACCACTTGGGCAATCGTAGGATTAGGGCGGTAGGGGAATTGTTGGCCAATGAATTGCATTCAGGTTTA
GTGAAAATGCAAAAGACCATTAAAGACAAGCTCACTACCATGAGCGGGGCTTTTGATTCGCTCATGCCCCATGACTTGGT
CAATTCTAAAATGATCACAAGCACCATCATGGAATTTTTCATGGGCGGTCAGCTCTCGCAATTTATGGATCAAACGAATC
CCTTGAGTGAGGTTACGCACAAGCGCCGCCTTTCAGCGCTCGGCGAAGGGGGGTTGGTGAAAGACAGAGTGGGGTTTGAA
GCCAGGGATGTGCACCCCACGCATTATGGCCGAATTTGTCCCATTGAGACCCCAGAAGGTCAAAATATCGGTCTGATCAA
CACCCTTTCCACTTTCACAAGAGTGAATGATTTAGGCTTTATTGAAGCCCCTTATAAAAAGGTTGTGGATGGCAAGGTCG
TGGGTGAGACGATTTATTTGACCGCTATTCAAGAAGACAGCCACATCATCGCTCCCGCAAGCACCCCCATTGATGAAGAG
GGGAATATTTTGGGCGATTTGATTGAAACGCGCGTGGAAGGCGAGATCGTTTTAAACGAAAAAAGCAAAGTAACCTTAAT
GGATTTAAGCTCTAGCATGCTAGTGGGGGTAGCCGCATCGCTCATTCCTTTCTTAGAGCATGATGACGCCAACCGTGCCT
TAATGGGGACTAACATGCAGCGCCAAGCGGTGCCCTTATTAAGAAGCGACGCTCCCATTGTAGGCACGGGGATTGAAAAA
ATTATTGCTAGGGATTCTTGGGGAGCGATCAAAGCCAATCGCGCAGGCGTTGTAGAAAAAATTGATTCTAAAAATATTTA
TATTTTAGGCGAAAGCAAAGAAGAAGCCTATATTGATGCGTATTCTTTGCAAAAAAACTTGCGCACCAACCAAAACACCA
GTTTCAATCAAGTCCCTATCGTTAAAGTGGGCGATAAAGTGGGAGCCGGGCAAATCATCGCTGATGGCCCTAGCATGGAT
AGAGGCGAGTTGGCGTTAGGGAAAAATGTGCGCGTGGCGTTCATGCCTTGGAATGGCTATAACTTTGAAGACGCGATCGT
GGTGAGTGAGTGCATCACTAAAGATGATATTTTCACTTCCACCCACATTTATGAAAAAGAAGTGGATGCTAGGGAGCTTA
AGCATGGTGTGGAAGAATTTACCGCTGATATTCCTGATGTGAAAGAAGAAGCGCTCGCTCATCTTGATGAAAGCGGGATC
GTTAAAGTCGGTACTTATGTGAGCGCTGGCATGATTTTGGTGGGCAAAACTTCTCCTAAAGGCGAGATTAAAAGCACGCC
TGAAGAGCGGCTTTTAAGGGCTATTTTTGGGGATAAAGCCGGGCATGTGGTCAATAAGAGTTTGTATTGCCCTCCCAGTT
TGGAAGGCACGGTGATTGATGTGAAAGTCTTCACTAAAAAAGGCTATGAGAAAGACGCGCGAGTTTTGAGCGCGTATGAA
GAAGAAAAAGCCAAGCTTGATATGGAGCATTTTGATCGCTTGACCATGCTCAATAGAGAAGAATTGTTGCGCGTTAGCTC
GCTCCTTTCTCAAGCGATTTTAGAAGAGCCTTTCAGCCATAACGGCAAGGATTATAAAGAAGGCGATCAAATCCCTAAAG
AAGAAATCGCTTCAATCAACCGCTTCACTTTGGCTAGTTTGGTCAAAAAGTATTCTAAAGAAGTGCAAAACCACTATGAA
ATCACTAAAAACAATTTCTTAGAGCAAAAGAAAGTTTTGGGCGAAGAGCATGAAGAAAAGCTTTCTATTTTAGAAAAAGA
TGATATTTTGCCTAATGGCGTGATCAAAAAAGTCAAGCTCTATATCGCTACAAAACGAAAGCTTAAAGTGGGCGATAAAA
TGGCAGGAAGGCATGGGAATAAAGGGATTGTGTCTAATATCGTGCCGGTTGCGGATATGCCTTATACCGCTGATGGCGAG
CCTGTAGATATTGTTTTAAACCCTTTAGGCGTGCCAAGCCGCATGAATATCGGGCAGATTTTAGAAATGCATTTAGGCTT
AGTGGGGAAAGAATTTGGGAAGCAAATCGCTCGCATGCTAGAGGATAAAACCAAAGATTTTGCCAAAGAATTGCGTGCTA
AAATGCTAGAAATCGCTAACGCTATTAATGAAAAAGACCCCTTGACAATCCATGCGCTTGAGAATTGTTCTGATGAAGAG
CTTTTGGAATACGCAAAAGATTGGAGCAAGGGCGTTAAGATGGCTATCCCTGTGTTTGAAGGCATCTCGCAAGAAAAATT
TTATAAGCTATTTGAATTAGCTAAGATCGCTATGGATGGCAAAATGGATCTGTATGACGGACGCACAGGCGAGAAAATGA
GGGAGCGCGTGAATGTGGGCTACATGTATATGATCAAACTCCACCATTTAGTGGATGAAAAAGTCCATGCCAGAAGCACA
GGCCCTTATAGCTTAGTAACGCACCAGCCCGTGGGGGGTAAAGCGCTCTTTGGGGGTCAAAGGTTTGGGGAAATGGAAGT
GTGGGCCTTGGAAGCTTATGGCGCAGCGCACACTCTAAAAGAAATGCTCACCATTAAATCCGATGATATTAGAGGCAGAG
AGAACGCTTATAGGGCTATCGCTAAAGGTGAGCAAGTGGGCGAGAGTGAAATCCCTGAGACTTTCTATGTTTTGACTAAA
GAATTGCAATCGCTCGCTTTGGATATTAATATTTTTGGGGACGATGTGGATGAGGATGGAGCACCTAAACCCATTGTCAT
TAAAGAAGATGACAGGCCTAAAGACTTTAGCTCTTTCCAGCTCACACTAGCTAGCCCTGAAAAAATCCATTCTTGGAGTT
ATGGGGAAGTTAAAAAGCCAGAAACGATCAATTATCGCACCCTAAAACCTGAACGAGACGGCTTGTTTTGCATGAAAATC
TTTGGCCCCACTAAAGATTATGAATGCTTGTGCGGCAAATACAAAAAGCCTCGCTTCAAAGACATTGGCACATGCGAAAA
ATGCGGCGTGGCGATCACGCACTCCAAAGTCAGGCGTTTTAGAATGGGGCATATTGAATTGGCCACTCCTGTAGCGCATA
TCTGGTATGTTAATTCCTTGCCTAGCCGTATCGGCACGCTTTTAGGCGTTAAGATGAAAGACTTAGAGCGCGTGTTGTAT
TATGAAGCTTATATCGTTAAAGAACCAGGCGAAGCCGCTTATGACAATGAAGGCACTAAGCTTGTGATGAAATACGATAT
TTTGAATGAAGAGCAGTATCAAAATATCTCACGAAGATACGAAGACAGGGGCTTTGTAGCGCAAATGGGCGGTGAAGCGA
TCAAGGATTTGTTAGAAGAAATTGATTTGATCACCTTATTGCAGAGTTTGAAAGAAGAAGTGAAAGACACCAATTCTGAT
GCGAAAAAGAAAAAACTCATTAAGCGTTTGAAAGTGGTAGAAAGCTTTTTAAATTCTGGTAATAGGCCTGAATGGATGAT
GCTCACGGTTTTACCGGTATTGCCACCGGATTTAAGGCCTTTAGTCGCGCTAGATGGCGGGAAGTTTGCAGTCAGCGATG
TGAATGAATTGTATCGTCGTGTCATCAATCGTAACCAACGCTTGAAACGCTTAATGGAGCTTGGAGCGCCAGAAATCATT
GTGCGCAATGAAAAAAGGATGTTGCAAGAAGCCGTGGATGTGCTTTTTGATAACGGCCGCAGCACTAATGCGGTTAAAGG
GGCTAACAAACGCCCTTTAAAATCGCTCAGTGAAATCATTAAAGGCAAGCAGGGGCGTTTCAGGCAAAACCTTTTAGGTA
AGCGCGTGGATTTTTCAGGCAGAAGCGTGATTGTGGTTGGGCCTAATCTCAAAATGGATGAATGCGGGTTGCCTAAAAAC
ATGGCGTTAGAACTCTTCAAACCGCATTTGTTATCCAAGCTTGAAGAGAGAGGCTATGCCACCACGCTCAAACAGGCTAA
ACGCATGATTGAGCAAAAAAGCAATGAAGTATGGGAGTGCTTGCAAGAAATCACAGAGGGGTATCCGGTGCTACTCAACC
GCGCTCCTACCTTGCACAAGCAATCCATTCAAGCGTTCCATCCAAAGCTGATTGACGGCAAAGCGATCCAATTGCACCCG
TTAGTGTGTTCAGCGTTCAACGCCGATTTTGACGGGGACCAAATGGCGGTGCATGTGCCTTTAAGCCAGGAAGCGATCGC
TGAATGCAAGGTGCTGATGCTAAGCTCTATGAATATCCTTTTGCCTGCTAGCGGTAAGGCCGTAGCCATTCCTAGCCAAG
ATATGGTTTTAGGGCTTTATTATCTTTCTTTAGAAAAGAGCGGGGTCAAGGGCGAGCATAAGCTTTTTTCTAGCGTGAAT
GAAATCATCACCGCCATTGACACGAAAGAATTAGACATCCACGCAAAGATTAGGGTTTTAGATCAAGGGAATATTATCGC
TACGAGTGCAGGGCGCATGATCATTAAGTCCATTTTGCCTGATTTTATCCCTACGGATTTGTGGAACAGACCCATGAAGA
AAAAAGATATTGGCGTGCTTGTGGATTATGTGCATAAAGTTGGCGGTATCGGTATTACTGCAACCTTTTTGGATAATTTA
AAAACGCTTGGCTTTAGGTATGCGACTAAGGCTGGTATTTCTATCTCTATGGAGGATATTATCACGCCAAAAGACAAGCA
AAAAATGGTGGAAAAAGCCAAAGTAGAGGTTAAAAAAATCCAGCAACAATACGATCAAGGGCTGCTCACTGACCAAGAGC
GTTACAATAAGATCATTGACACTTGGACTGAAGTCAATGACAAAATGAGTAAAGAAATGATGACCGCTATCGCGCAAGAT
AAAGAGGGCTTTAACTCTATTTATATGATGGCAGATAGCGGCGCAAGGGGTAGCGCGGCGCAAATCCGTCAGCTTTCAGC
GATGAGGGGTCTTATGACAAAGCCGGACGGCAGTATCATTGAAACGCCCATTATTTCTAACTTTAAAGAGGGGTTGAATG
TCTTAGAATACTTCAATTCCACGCATGGCGCTAGAAAGGGCTTAGCGGATACAGCGCTAAAAACAGCCAATGCGGGGTAT
TTGACCAGAAAGCTCATTGATGTTTCGCAAAATGTCAAGGTGGTGTCTGATGATTGCGGCACGCATGAAGGGATTGAAAT
CACGGATATTGCGGTGGGGAGTGAGCTGATTGAACCTTTAGAAGAGCGTATTTTTGGGCGCGTTTTATTAGAAGATGTGA
TCGATCCCATTACGAATGAAATCTTGCTTTATGCGGACACTTTGATTGATGAAGAGGGTGCTAAAAAGGTGGTTGAAGCC
GGGATTAAATCCATTACGATCCGCACCCCAGTAACTTGTAAAGCGCCAAAGGGCGTGTGCGCGAAATGCTATGGCTTGAA
TTTGGGCGAAGGCAAGATGAGTTATCCGGGTGAAGCGGTGGGCGTGGTAGCCGCGCAATCTATTGGGGAGCCTGGAACGC
AGCTCACTTTAAGGACTTTCCATGTGGGCGGGACAGCGAGCAGGAGTCAGGATGAGCGCGAAATCGTAGCGAGCAAAGAA
GGTTTTGTGCGTTTTTACAACCTTAGGACTTACACGAATAAAGAGGGTAAAAACATTATCGCTAACCGCCGTAACGCTTC
TATTTTAGTGGTAGAGCCTAAGATTAAAGCGCCTTTTGATGGGGAATTACGCATTGAAACGGTTTATGAAGAAGTCGTTG
TGAGCGTGAAAAATGGCGATCAAGAAGCTAAATTTGTTTTAAGGAGAAGCGATATTGTCAAGCCAAGCGAATTAGCCGGC
GTTGGCGGTAAGATTGAGGGGAAAGTGTATTTGCCTTATGCTAGTGGGCATAAGGTGCATAAGGGGGGAAGTATCGCTGA
TATTATCCAAGAGGGCTGGAATGTGCCTAATCGCATCCCTTATGCGAGCGAATTGCTAGTCAAGGATAATGACCCTATTG
CGCAAGATGTGTATGCCAAAGAAAAAGGCGTAATCAAATACTATGTTTTAGAGGCTAACCATTTAGAGCGCACCCATGGG
ATCAAAAAGGGCGATATGGTGAGTGAAAAAGGCTTGTTTGCGGTGATAGCTGATGATAATGGTAGGGAAGCCGCTCGCCA
TTATATCGCTAGGGGTTCTGAGATCTTGATTGATGATAATAGTGAAGTGAGCACTAATAGCGTGATTTCTAAACCCACGA
CTAACACTTTCAAAACGATTGCCACATGGGATCCTTACAACACCCCTATCATTGCGGACTTTAAAGGTAAGGTGGGTTTT
GTGGATGTTATCGCAGGGGTTACGGTCGCTGAAAAAGAAGACGAAAATACCGGTATCACAAGCTTAGTGGTGAATGATTA
CATTCCAAGCGGATACAAACCAAGCTTGTTTTTAGAGGGGGCTAATGGCGAAGAGATGCGTTATTTCCTAGAGCCAAAAA
CCTCTATCGCCATTAGCGATGGCTCTAGCGTGGAGCAAGCTGAAGTGTTAGCGAAAATCCCTAAAGCGACCGTTAAATCT
AGGGATATTACCGGGGGTCTCCCAAGGGTTTCGGAACTCTTTGAAGCGAGAAAACCCAAGCCTAAAGATGTGGCGATCCT
TTCTGAAGTTGATGGGATTGTGAGTTTTGGCAAACCCATTCGCAATAAAGAACACATCATCGTAACTTCTAAAGATGGCC
GTTCCATGGATTATTTTGTGGATAAAGGCAAGCAAATTTTAGTGCATGCCGATGAATTTGTGCATGCGGGAGAAGCGATG
ACGGACGGAGTAATTTCAAGCCATGATATTTTAAGGATCAGTGGCGAAAAAGAGCTTTATAAATACATTGTGAGCGAAGT
CCAGCAAGTGTATCGCAGGCAGGGGGTGAGCATTGCGGACAAGCACATTGAAATCATTGTTTCTCAAATGCTAAGACAGG
TGCGTATTTTAGACAGCGGGGATAGCAAGTTTATTGAAGGGGATTTAGTCAGTAAAAAACTTTTCAAAGAAGAAAACGCT
CGTGTGATCGCTTTAAAAGGCGAGCCAGCGATTGCTGAACCGGTGCTTTTAGGGATCACTAGAGCGGCTATTGGGAGCGA
TAGCATCATCTCAGCGGCCTCTTTCCAAGAAACGACTAAAGTTTTAACAGAAGCCAGTATCGCTATGAAAAAAGACTTTT
TAGAGGATTTGAAAGAGAATGTGGTGTTGGGGAGGATGATCCCTGTGGGAACAGGCATGTATAAGAATAAAAAAATCGTG
TTAAGAGCGCTTGAGGATAACTCTAAATTTTGA

Upstream 100 bases:

>100_bases
TTTTTATCATGGATGGTTCTAAAGTTTAAAGATCCTTTTGCAATGCTTACTTGAATTAATGCATTAAATAACTCAAAATT
TTTGATCAAAGGCTTGAAAT

Downstream 100 bases:

>100_bases
TATGAAAAATCGGTTAAGATTTTTAAAAGAAAAATTAGGGTAAAATGGGGGAACTTTTAGTTTTAAATTTTTAGAATAAG
GAAAAATAGTGCCTACTATC

Product: DNA-directed RNA polymerase subunit beta/beta'

Products: NA

Alternate protein names: DNA-directed RNA polymerase subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta; DNA-directed RNA polymerase subunit beta'; RNA polymerase beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 2890; Mature: 2889

Protein sequence:

>2890_residues
MSKKIPLKNRLRADFTKTPTDLEVPNLLLLQRDSYDSFLYSKEGKESGIEKVFKSIFPIQDEHNRITLEYAGCEFGKSKY
TVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDIKEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIF
KEEESSTSLNKLIYTGQIIPDRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
IPFASLDANQRMEFDLKDPQGKVILLAGKKLTSRKIKELKENHLEWVEYPMDILLNRHLAEPVMVGKEVLLDMLTQLDKN
KLEKIHDLGVQEFVIINDLALGHDASIIQSFSADSESLKLLKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKL
FFDPERYDLTMVGRMKMNHKLGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
VKMQKTIKDKLTTMSGAFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKDRVGFE
ARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGFIEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEE
GNILGDLIETRVEGEIVLNEKSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPIVGTGIEK
IIARDSWGAIKANRAGVVEKIDSKNIYILGESKEEAYIDAYSLQKNLRTNQNTSFNQVPIVKVGDKVGAGQIIADGPSMD
RGELALGKNVRVAFMPWNGYNFEDAIVVSECITKDDIFTSTHIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGI
VKVGTYVSAGMILVGKTSPKGEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASINRFTLASLVKKYSKEVQNHYE
ITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKLYIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGE
PVDIVLNPLGVPSRMNIGQILEMHLGLVGKEFGKQIARMLEDKTKDFAKELRAKMLEIANAINEKDPLTIHALENCSDEE
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVGYMYMIKLHHLVDEKVHARST
GPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLKEMLTIKSDDIRGRENAYRAIAKGEQVGESEIPETFYVLTK
ELQSLALDINIFGDDVDEDGAPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSLPSRIGTLLGVKMKDLERVLY
YEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRYEDRGFVAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSD
AKKKKLIKRLKVVESFLNSGNRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPNLKMDECGLPKN
MALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWECLQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHP
LVCSAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKAVAIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVLVDYVHKVGGIGITATFLDNL
KTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKIQQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMTAIAQD
KEGFNSIYMMADSGARGSAAQIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNEILLYADTLIDEEGAKKVVEA
GIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAVGVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKE
GFVRFYNLRTYTNKEGKNIIANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGDQEAKFVLRRSDIVKPSELAG
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAKEKGVIKYYVLEANHLERTHG
IKKGDMVSEKGLFAVIADDNGREAARHYIARGSEILIDDNSEVSTNSVISKPTTNTFKTIATWDPYNTPIIADFKGKVGF
VDVIAGVTVAEKEDENTGITSLVVNDYIPSGYKPSLFLEGANGEEMRYFLEPKTSIAISDGSSVEQAEVLAKIPKATVKS
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRSMDYFVDKGKQILVHADEFVHAGEAM
TDGVISSHDILRISGEKELYKYIVSEVQQVYRRQGVSIADKHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENA
RVIALKGEPAIAEPVLLGITRAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
LRALEDNSKF

Sequences:

>Translated_2890_residues
MSKKIPLKNRLRADFTKTPTDLEVPNLLLLQRDSYDSFLYSKEGKESGIEKVFKSIFPIQDEHNRITLEYAGCEFGKSKY
TVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDIKEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIF
KEEESSTSLNKLIYTGQIIPDRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
IPFASLDANQRMEFDLKDPQGKVILLAGKKLTSRKIKELKENHLEWVEYPMDILLNRHLAEPVMVGKEVLLDMLTQLDKN
KLEKIHDLGVQEFVIINDLALGHDASIIQSFSADSESLKLLKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKL
FFDPERYDLTMVGRMKMNHKLGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
VKMQKTIKDKLTTMSGAFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKDRVGFE
ARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGFIEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEE
GNILGDLIETRVEGEIVLNEKSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPIVGTGIEK
IIARDSWGAIKANRAGVVEKIDSKNIYILGESKEEAYIDAYSLQKNLRTNQNTSFNQVPIVKVGDKVGAGQIIADGPSMD
RGELALGKNVRVAFMPWNGYNFEDAIVVSECITKDDIFTSTHIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGI
VKVGTYVSAGMILVGKTSPKGEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASINRFTLASLVKKYSKEVQNHYE
ITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKLYIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGE
PVDIVLNPLGVPSRMNIGQILEMHLGLVGKEFGKQIARMLEDKTKDFAKELRAKMLEIANAINEKDPLTIHALENCSDEE
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVGYMYMIKLHHLVDEKVHARST
GPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLKEMLTIKSDDIRGRENAYRAIAKGEQVGESEIPETFYVLTK
ELQSLALDINIFGDDVDEDGAPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSLPSRIGTLLGVKMKDLERVLY
YEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRYEDRGFVAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSD
AKKKKLIKRLKVVESFLNSGNRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPNLKMDECGLPKN
MALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWECLQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHP
LVCSAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKAVAIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVLVDYVHKVGGIGITATFLDNL
KTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKIQQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMTAIAQD
KEGFNSIYMMADSGARGSAAQIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNEILLYADTLIDEEGAKKVVEA
GIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAVGVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKE
GFVRFYNLRTYTNKEGKNIIANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGDQEAKFVLRRSDIVKPSELAG
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAKEKGVIKYYVLEANHLERTHG
IKKGDMVSEKGLFAVIADDNGREAARHYIARGSEILIDDNSEVSTNSVISKPTTNTFKTIATWDPYNTPIIADFKGKVGF
VDVIAGVTVAEKEDENTGITSLVVNDYIPSGYKPSLFLEGANGEEMRYFLEPKTSIAISDGSSVEQAEVLAKIPKATVKS
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRSMDYFVDKGKQILVHADEFVHAGEAM
TDGVISSHDILRISGEKELYKYIVSEVQQVYRRQGVSIADKHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENA
RVIALKGEPAIAEPVLLGITRAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
LRALEDNSKF
>Mature_2889_residues
SKKIPLKNRLRADFTKTPTDLEVPNLLLLQRDSYDSFLYSKEGKESGIEKVFKSIFPIQDEHNRITLEYAGCEFGKSKYT
VREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDIKEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIFK
EEESSTSLNKLIYTGQIIPDRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYLI
PFASLDANQRMEFDLKDPQGKVILLAGKKLTSRKIKELKENHLEWVEYPMDILLNRHLAEPVMVGKEVLLDMLTQLDKNK
LEKIHDLGVQEFVIINDLALGHDASIIQSFSADSESLKLLKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKLF
FDPERYDLTMVGRMKMNHKLGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGLV
KMQKTIKDKLTTMSGAFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKDRVGFEA
RDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGFIEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEEG
NILGDLIETRVEGEIVLNEKSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPIVGTGIEKI
IARDSWGAIKANRAGVVEKIDSKNIYILGESKEEAYIDAYSLQKNLRTNQNTSFNQVPIVKVGDKVGAGQIIADGPSMDR
GELALGKNVRVAFMPWNGYNFEDAIVVSECITKDDIFTSTHIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGIV
KVGTYVSAGMILVGKTSPKGEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYEE
EKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASINRFTLASLVKKYSKEVQNHYEI
TKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKLYIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGEP
VDIVLNPLGVPSRMNIGQILEMHLGLVGKEFGKQIARMLEDKTKDFAKELRAKMLEIANAINEKDPLTIHALENCSDEEL
LEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVGYMYMIKLHHLVDEKVHARSTG
PYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLKEMLTIKSDDIRGRENAYRAIAKGEQVGESEIPETFYVLTKE
LQSLALDINIFGDDVDEDGAPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKIF
GPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSLPSRIGTLLGVKMKDLERVLYY
EAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRYEDRGFVAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSDA
KKKKLIKRLKVVESFLNSGNRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEIIV
RNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPNLKMDECGLPKNM
ALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWECLQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHPL
VCSAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKAVAIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVNE
IITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVLVDYVHKVGGIGITATFLDNLK
TLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKIQQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMTAIAQDK
EGFNSIYMMADSGARGSAAQIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGYL
TRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNEILLYADTLIDEEGAKKVVEAG
IKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAVGVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKEG
FVRFYNLRTYTNKEGKNIIANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGDQEAKFVLRRSDIVKPSELAGV
GGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAKEKGVIKYYVLEANHLERTHGI
KKGDMVSEKGLFAVIADDNGREAARHYIARGSEILIDDNSEVSTNSVISKPTTNTFKTIATWDPYNTPIIADFKGKVGFV
DVIAGVTVAEKEDENTGITSLVVNDYIPSGYKPSLFLEGANGEEMRYFLEPKTSIAISDGSSVEQAEVLAKIPKATVKSR
DITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRSMDYFVDKGKQILVHADEFVHAGEAMT
DGVISSHDILRISGEKELYKYIVSEVQQVYRRQGVSIADKHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENAR
VIALKGEPAIAEPVLLGITRAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIVL
RALEDNSKF

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=847, Percent_Identity=26.0920897284534, Blast_Score=195, Evalue=5e-49,
Organism=Homo sapiens, GI39725938, Length=314, Percent_Identity=31.2101910828025, Blast_Score=137, Evalue=1e-31,
Organism=Homo sapiens, GI103471997, Length=605, Percent_Identity=25.1239669421488, Blast_Score=121, Evalue=9e-27,
Organism=Homo sapiens, GI33469941, Length=257, Percent_Identity=30.7392996108949, Blast_Score=116, Evalue=3e-25,
Organism=Homo sapiens, GI212286172, Length=257, Percent_Identity=30.7392996108949, Blast_Score=116, Evalue=4e-25,
Organism=Homo sapiens, GI4505941, Length=169, Percent_Identity=29.585798816568, Blast_Score=82, Evalue=9e-15,
Organism=Homo sapiens, GI238908503, Length=138, Percent_Identity=36.231884057971, Blast_Score=75, Evalue=1e-12,
Organism=Homo sapiens, GI238908505, Length=138, Percent_Identity=36.231884057971, Blast_Score=75, Evalue=1e-12,
Organism=Escherichia coli, GI1790419, Length=1389, Percent_Identity=46.4362850971922, Blast_Score=1215, Evalue=0.0,
Organism=Escherichia coli, GI2367335, Length=990, Percent_Identity=54.6464646464646, Blast_Score=1113, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=899, Percent_Identity=25.5839822024472, Blast_Score=189, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI25145495, Length=490, Percent_Identity=28.3673469387755, Blast_Score=145, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17552304, Length=308, Percent_Identity=29.5454545454545, Blast_Score=119, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25144348, Length=146, Percent_Identity=34.2465753424658, Blast_Score=78, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17506623, Length=111, Percent_Identity=36.9369369369369, Blast_Score=70, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320061, Length=890, Percent_Identity=24.7191011235955, Blast_Score=202, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6324690, Length=328, Percent_Identity=31.4024390243902, Blast_Score=140, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324725, Length=257, Percent_Identity=31.1284046692607, Blast_Score=120, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6325267, Length=256, Percent_Identity=28.125, Blast_Score=101, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324781, Length=155, Percent_Identity=34.8387096774194, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17530899, Length=837, Percent_Identity=25.3285543608124, Blast_Score=179, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281360912, Length=310, Percent_Identity=30.6451612903226, Blast_Score=134, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17647875, Length=357, Percent_Identity=27.4509803921569, Blast_Score=112, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136446, Length=320, Percent_Identity=27.5, Blast_Score=100, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17136444, Length=169, Percent_Identity=29.585798816568, Blast_Score=82, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17647877, Length=89, Percent_Identity=42.6966292134831, Blast_Score=74, Evalue=2e-12,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR007120
- InterPro:   IPR000722
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5; PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_po

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 323579; Mature: 323448

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKIPLKNRLRADFTKTPTDLEVPNLLLLQRDSYDSFLYSKEGKESGIEKVFKSIFPIQ
CCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHCCCCCHHHHHHHHHHHHCCCC
DEHNRITLEYAGCEFGKSKYTVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDI
CCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECEEEEEEEEEEECCCCCCCCCCHHHH
KEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIFKEEESSTSLNKLIYTGQIIP
HHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHEEEECEEEC
DRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
CCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHEEEECCCCEE
IPFASLDANQRMEFDLKDPQGKVILLAGKKLTSRKIKELKENHLEWVEYPMDILLNRHLA
EEEECCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPVMVGKEVLLDMLTQLDKNKLEKIHDLGVQEFVIINDLALGHDASIIQSFSADSESLKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHCCCHHHHHH
LKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKLFFDPERYDLTMVGRMKMNHK
HHHHHHCCCCCCEEHEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
LGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
VKMQKTIKDKLTTMSGAFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTH
HHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHH
KRRLSALGEGGLVKDRVGFEARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGF
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCC
IEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEEGNILGDLIETRVEGEIVLNE
CCCCHHHHCCCEEECCEEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHCCCCEEEECC
KSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPIVGTGIEK
CCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHCHHHHCCCCEEECCHHH
IIARDSWGAIKANRAGVVEKIDSKNIYILGESKEEAYIDAYSLQKNLRTNQNTSFNQVPI
HHHCCCCCCEECCCCCHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEE
VKVGDKVGAGQIIADGPSMDRGELALGKNVRVAFMPWNGYNFEDAIVVSECITKDDIFTS
EEECCCCCCCCEEECCCCCCCCCEEECCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCC
THIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGIVKVGTYVSAGMILVGKTSPK
CHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEEECCEEEEECCCCC
GEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
CCCCCCHHHHHHHHHHCCCCCCEECCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHH
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASIN
HHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
RFTLASLVKKYSKEVQNHYEITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHEEE
YIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGEPVDIVLNPLGVPSRMNIGQI
EEEECCHHCCCCHHCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHH
LEMHLGLVGKEFGKQIARMLEDKTKDFAKELRAKMLEIANAINEKDPLTIHALENCSDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVG
HHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHCCC
YMYMIKLHHLVDEKVHARSTGPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLK
EEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEEHHCHHHHHH
EMLTIKSDDIRGRENAYRAIAKGEQVGESEIPETFYVLTKELQSLALDINIFGDDVDEDG
HHHHHCCCCCCCHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHEEEEEEECCCCCCCC
APKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
CCCCEEECCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEEE
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSL
CCCCCCHHHHHCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHCCCEEECCHHHHEEEHHHH
PSRIGTLLGVKMKDLERVLYYEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRY
HHHHHHHHCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHH
EDRGFVAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSDAKKKKLIKRLKVVESFLNSG
HCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
NRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
CCCCEEEEEEECCCCCCCCCEEEECCCCEEHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSG
EECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
RSVIVVGPNLKMDECGLPKNMALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWEC
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHH
LQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHPLVCSAFNADFDGDQMAVHVP
HHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCCCCCCCEEEEEC
LSQEAIAECKVLMLSSMNILLPASGKAVAIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
CCHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHH
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVL
HHHHHHCCCEEEEEEEEEEEECCCEEEECCHHHHHHHHCHHHCCHHHHCCCCCCCHHHHH
VDYVHKVGGIGITATFLDNLKTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKI
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHH
QQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMTAIAQDKEGFNSIYMMADSGARGSAA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
QIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
HHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHCCCCH
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNE
HHHHHHHHCCCCEEEECCCCCCCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLYADTLIDEEGAKKVVEAGIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAV
EEEEHHHHHCCHHHHHHHHCCHHEEEEECCCEECCCCCCCHHHCCCCCCCCCCCCCCCHH
GVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKEGFVRFYNLRTYTNKEGKNII
HHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEEEECCCCCCEEE
ANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGDQEAKFVLRRSDIVKPSELAG
ECCCCCEEEEECCCCCCCCCCCEEHHEEHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHCC
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAK
CCCEECCEEEEEECCCCEECCCCCHHHHHHHHCCCCCCCCCHHEEEEECCCCHHHHHHHH
EKGVIKYYVLEANHLERTHGIKKGDMVSEKGLFAVIADDNGREAARHYIARGSEILIDDN
CCCCEEEEEEECCHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEECC
SEVSTNSVISKPTTNTFKTIATWDPYNTPIIADFKGKVGFVDVIAGVTVAEKEDENTGIT
CCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCHHHHHHCCEEECCCCCCCCCE
SLVVNDYIPSGYKPSLFLEGANGEEMRYFLEPKTSIAISDGSSVEQAEVLAKIPKATVKS
EEEEECCCCCCCCCCEEEECCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHCCHHHHCC
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRSMDYFV
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHH
DKGKQILVHADEFVHAGEAMTDGVISSHDILRISGEKELYKYIVSEVQQVYRRQGVSIAD
CCCCEEEEECHHHHHCCCHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHH
KHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENARVIALKGEPAIAEPVLLGIT
HHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
RAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCEEE
LRALEDNSKF
EEEECCCCCC
>Mature Secondary Structure 
SKKIPLKNRLRADFTKTPTDLEVPNLLLLQRDSYDSFLYSKEGKESGIEKVFKSIFPIQ
CCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHCCCCCHHHHHHHHHHHHCCCC
DEHNRITLEYAGCEFGKSKYTVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDI
CCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECEEEEEEEEEEECCCCCCCCCCHHHH
KEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIFKEEESSTSLNKLIYTGQIIP
HHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHEEEECEEEC
DRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
CCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHEEEECCCCEE
IPFASLDANQRMEFDLKDPQGKVILLAGKKLTSRKIKELKENHLEWVEYPMDILLNRHLA
EEEECCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPVMVGKEVLLDMLTQLDKNKLEKIHDLGVQEFVIINDLALGHDASIIQSFSADSESLKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHCCCHHHHHH
LKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKLFFDPERYDLTMVGRMKMNHK
HHHHHHCCCCCCEEHEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
LGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
VKMQKTIKDKLTTMSGAFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTH
HHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHH
KRRLSALGEGGLVKDRVGFEARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGF
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCC
IEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEEGNILGDLIETRVEGEIVLNE
CCCCHHHHCCCEEECCEEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHCCCCEEEECC
KSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPIVGTGIEK
CCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHCHHHHCCCCEEECCHHH
IIARDSWGAIKANRAGVVEKIDSKNIYILGESKEEAYIDAYSLQKNLRTNQNTSFNQVPI
HHHCCCCCCEECCCCCHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEE
VKVGDKVGAGQIIADGPSMDRGELALGKNVRVAFMPWNGYNFEDAIVVSECITKDDIFTS
EEECCCCCCCCEEECCCCCCCCCEEECCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCC
THIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGIVKVGTYVSAGMILVGKTSPK
CHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEEECCEEEEECCCCC
GEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
CCCCCCHHHHHHHHHHCCCCCCEECCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHH
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASIN
HHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
RFTLASLVKKYSKEVQNHYEITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHEEE
YIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGEPVDIVLNPLGVPSRMNIGQI
EEEECCHHCCCCHHCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHH
LEMHLGLVGKEFGKQIARMLEDKTKDFAKELRAKMLEIANAINEKDPLTIHALENCSDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVG
HHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHCCC
YMYMIKLHHLVDEKVHARSTGPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLK
EEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEEHHCHHHHHH
EMLTIKSDDIRGRENAYRAIAKGEQVGESEIPETFYVLTKELQSLALDINIFGDDVDEDG
HHHHHCCCCCCCHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHEEEEEEECCCCCCCC
APKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
CCCCEEECCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEEE
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSL
CCCCCCHHHHHCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHCCCEEECCHHHHEEEHHHH
PSRIGTLLGVKMKDLERVLYYEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRY
HHHHHHHHCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHH
EDRGFVAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSDAKKKKLIKRLKVVESFLNSG
HCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
NRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
CCCCEEEEEEECCCCCCCCCEEEECCCCEEHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSG
EECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
RSVIVVGPNLKMDECGLPKNMALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWEC
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHH
LQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHPLVCSAFNADFDGDQMAVHVP
HHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCCCCCCCEEEEEC
LSQEAIAECKVLMLSSMNILLPASGKAVAIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
CCHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHH
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVL
HHHHHHCCCEEEEEEEEEEEECCCEEEECCHHHHHHHHCHHHCCHHHHCCCCCCCHHHHH
VDYVHKVGGIGITATFLDNLKTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKI
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHH
QQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMTAIAQDKEGFNSIYMMADSGARGSAA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
QIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
HHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHCCCCH
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNE
HHHHHHHHCCCCEEEECCCCCCCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLYADTLIDEEGAKKVVEAGIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAV
EEEEHHHHHCCHHHHHHHHCCHHEEEEECCCEECCCCCCCHHHCCCCCCCCCCCCCCCHH
GVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKEGFVRFYNLRTYTNKEGKNII
HHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEEEECCCCCCEEE
ANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGDQEAKFVLRRSDIVKPSELAG
ECCCCCEEEEECCCCCCCCCCCEEHHEEHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHCC
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAK
CCCEECCEEEEEECCCCEECCCCCHHHHHHHHCCCCCCCCCHHEEEEECCCCHHHHHHHH
EKGVIKYYVLEANHLERTHGIKKGDMVSEKGLFAVIADDNGREAARHYIARGSEILIDDN
CCCCEEEEEEECCHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEECC
SEVSTNSVISKPTTNTFKTIATWDPYNTPIIADFKGKVGFVDVIAGVTVAEKEDENTGIT
CCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCHHHHHHCCEEECCCCCCCCCE
SLVVNDYIPSGYKPSLFLEGANGEEMRYFLEPKTSIAISDGSSVEQAEVLAKIPKATVKS
EEEEECCCCCCCCCCEEEECCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHCCHHHHCC
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRSMDYFV
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHH
DKGKQILVHADEFVHAGEAMTDGVISSHDILRISGEKELYKYIVSEVQQVYRRQGVSIAD
CCCCEEEEECHHHHHCCCHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHH
KHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENARVIALKGEPAIAEPVLLGIT
HHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
RAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCEEE
LRALEDNSKF
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA