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Identifier: 15645803

GI number: 15645803

Start: 1259619

End: 1260659

Strand: Reverse

Name: Not Available

Synonym: HP1189

Alternate gene names: 15645803

Gene position: 1260659-1259619 (Counterclockwise)

Preceding gene: 15645804

Following gene: 15645802

Centisome position: 75.59

GC content: 42.36

Gene sequence:

>1041_bases
ATGAAGACTTATAATGTCGCTATTGTTGGGGCCAGTGGGGCGGTAGGCCAAGAGCTGATTAAGGGTTTAGAAAATTCTTT
TTTCCCAATTAAAAAATTTGTCCCGCTCGCTAGCACTAGGAGTGCTGGTAAAAAGATCAAAGCTTTCAATAAAGACTATG
AAATTTTAGAAACCACGCATGAAGTTTTTGAAAGAGAAAAAATAGACATCGCCTTTTTTAGCGCTGGGGGGAGCGTGAGC
GAAGAATTTGCTACAAGCGCTTCAAAAACGGCCTTAGTGGTTGATAACACGAGCTTTTTTAGATTGAATAAAGATGTGCC
TTTAGTCGTTCCTGAAATCAACGCTAAAGAAATTTTTAACGCTCCCTTGAATATCATCGCTAACCCTAATTGCTCCACCA
TTCAAATGACGCAAATCTTAAACCCCTTACATCTCCATTTTAAGATAAAAAGCGTGATTGTTAGCACCTATCAAGCCGTG
AGTGGGGCAGGGAACAAGGGCATAGAGAGTTTAAAAAATGAGTTAAAAACCGCTTTAGAGTGTTTGGAAAAAGACCCCAC
TATTGATTTAAACCAAGTCTTGCAAGCTGGGGCTTTCGCTTATCCGATCGCTTTCAATGCGATCGCTCATATTGATACTT
TTAAGGAGAATGGTTACACGAAAGAAGAGCTAAAAATGCTGCATGAAACCCATAAAATCATGGGCGTGGATTTCCCTATC
AGCGCGACTTGCGTGCGCGTGCCGGTATTGAGGAGCCATAGCGAGAGTTTGAGTATCGCTTTTGAAAAAGAATTCGATCT
CAAAGAAGTCTATGAAGTTTTAAAAAACGCCCCTAGCGTGGCTGTTTGCGATGATCCCAGTCATAATCTTTACCCCACGC
CCCTAAAAGCGAGCCACACGGATAGCGTCTTTATAGGGCGCTTGAGGAAGGATTTGTTTGATAAGAAAACTTTGCATGGC
TTTTGTGTGGCGGATCAATTGAGAGTGGGGGCAGCCACCAACGCACTCAAAATCGCTCTGCATTACATTAAGAACGCTTG
A

Upstream 100 bases:

>100_bases
GAATTTAAAAGCGAAACTTTAAGCTTGAAAAACATGCATTCAGGCATGCAGTTGAATTGCTTGAGTTTTTTAAAAGCCCT
TGAAATCATTGGAGAAAACG

Downstream 100 bases:

>100_bases
GTTTATTCAAAGATAACAAAGATGAATGTGCATGCGCTTGAATTAAGGATAAGGATCAATCTAGCCCAATCTCTAAAGAA
GAGCTTTAAGTTACTAGGCT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKTYNVAIVGASGAVGQELIKGLENSFFPIKKFVPLASTRSAGKKIKAFNKDYEILETTHEVFEREKIDIAFFSAGGSVS
EEFATSASKTALVVDNTSFFRLNKDVPLVVPEINAKEIFNAPLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAV
SGAGNKGIESLKNELKTALECLEKDPTIDLNQVLQAGAFAYPIAFNAIAHIDTFKENGYTKEELKMLHETHKIMGVDFPI
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVAVCDDPSHNLYPTPLKASHTDSVFIGRLRKDLFDKKTLHG
FCVADQLRVGAATNALKIALHYIKNA

Sequences:

>Translated_346_residues
MKTYNVAIVGASGAVGQELIKGLENSFFPIKKFVPLASTRSAGKKIKAFNKDYEILETTHEVFEREKIDIAFFSAGGSVS
EEFATSASKTALVVDNTSFFRLNKDVPLVVPEINAKEIFNAPLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAV
SGAGNKGIESLKNELKTALECLEKDPTIDLNQVLQAGAFAYPIAFNAIAHIDTFKENGYTKEELKMLHETHKIMGVDFPI
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVAVCDDPSHNLYPTPLKASHTDSVFIGRLRKDLFDKKTLHG
FCVADQLRVGAATNALKIALHYIKNA
>Mature_346_residues
MKTYNVAIVGASGAVGQELIKGLENSFFPIKKFVPLASTRSAGKKIKAFNKDYEILETTHEVFEREKIDIAFFSAGGSVS
EEFATSASKTALVVDNTSFFRLNKDVPLVVPEINAKEIFNAPLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAV
SGAGNKGIESLKNELKTALECLEKDPTIDLNQVLQAGAFAYPIAFNAIAHIDTFKENGYTKEELKMLHETHKIMGVDFPI
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVAVCDDPSHNLYPTPLKASHTDSVFIGRLRKDLFDKKTLHG
FCVADQLRVGAATNALKIALHYIKNA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=347, Percent_Identity=26.5129682997118, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789841, Length=356, Percent_Identity=27.5280898876405, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38116; Mature: 38116

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYNVAIVGASGAVGQELIKGLENSFFPIKKFVPLASTRSAGKKIKAFNKDYEILETTH
CCEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHCCCCCCHHCCHHHHHCCCCHHHHHHHH
EVFEREKIDIAFFSAGGSVSEEFATSASKTALVVDNTSFFRLNKDVPLVVPEINAKEIFN
HHHHCCCCEEEEEECCCCCHHHHHCCCCCEEEEEECCEEEEECCCCCEEECCCCHHHHHC
APLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAVSGAGNKGIESLKNELKTALE
CCCEEEECCCCCEEEHHHHCCCHHEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
CLEKDPTIDLNQVLQAGAFAYPIAFNAIAHIDTFKENGYTKEELKMLHETHKIMGVDFPI
HHHCCCCCCHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCC
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVAVCDDPSHNLYPTPLKASHT
CCHHEEEHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCC
DSVFIGRLRKDLFDKKTLHGFCVADQLRVGAATNALKIALHYIKNA
CHHHHHHHHHHHHHHHHHCCEEEHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTYNVAIVGASGAVGQELIKGLENSFFPIKKFVPLASTRSAGKKIKAFNKDYEILETTH
CCEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHCCCCCCHHCCHHHHHCCCCHHHHHHHH
EVFEREKIDIAFFSAGGSVSEEFATSASKTALVVDNTSFFRLNKDVPLVVPEINAKEIFN
HHHHCCCCEEEEEECCCCCHHHHHCCCCCEEEEEECCEEEEECCCCCEEECCCCHHHHHC
APLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAVSGAGNKGIESLKNELKTALE
CCCEEEECCCCCEEEHHHHCCCHHEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
CLEKDPTIDLNQVLQAGAFAYPIAFNAIAHIDTFKENGYTKEELKMLHETHKIMGVDFPI
HHHCCCCCCHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCC
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVAVCDDPSHNLYPTPLKASHT
CCHHEEEHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCC
DSVFIGRLRKDLFDKKTLHGFCVADQLRVGAATNALKIALHYIKNA
CHHHHHHHHHHHHHHHHHCCEEEHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]