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Identifier: 15645794

GI number: 15645794

Start: 1247915

End: 1249171

Strand: Reverse

Name: Not Available

Synonym: HP1180

Alternate gene names: 15645794

Gene position: 1249171-1247915 (Counterclockwise)

Preceding gene: 15645797

Following gene: 15645793

Centisome position: 74.9

GC content: 44.79

Gene sequence:

>1257_bases
ATGATTTTTAGCTCTCTTTTTAGTGTTGTAGGGATGGCGGTGCTTTTTCTTATTGCTTGGGTGTTTTCTAGCAATAAAAG
GGCTATTAATTATCGCACGATTGTCAGTGCCTTTGTGATTCAAGTGGCTTTAGGGGCGTTGGCTTTATATGTGCCTTTGG
GTAGGGAAATGCTGCAAGGCTTAGCCAGCGGCATACAAAGCGTGATTTCTTACGGCTATGAGGGGGTGCGTTTTTTATTT
GGCAATCTCGCTCCAAACGCTAAGGGCGATCAAGGGATAGGGGGGTTTGTCTTTGCGATCAATGTTTTAGCGATCATTAT
CTTTTTTGCTAGCTTGATTTCACTTCTATATTATTTAAAAATCATGCCTTTATTTATCAATCTCATCGGTGGGGCGTTGC
AAAAATGCTTAGGCACTTCTAGAGCAGAAAGCATGAGTGCAGCGGCTAATATTTTTGTAGCGCACACCGAAGCGCCCTTA
GTCATTAAACCTTATTTGAAAAGCATGAGCGATTCAGAGATTTTTGCGGTCATGTGCGTGGGCATGGCTAGCGTTGCGGG
GCCTGTGTTAGCCGGGTATGCGAGCATGGGCATTCCTTTGCCTTATTTGATCGCCGCTTCGTTTATGTCCGCTCCTGGGG
GGTTGTTGTTCGCTAAAATCATTTACCCACAAAACGAAACCATTTCTAGCCATGCAGATGTTTCTATAGAAAAGCATGTC
AATGCCATAGAAGCTATCGCTAATGGGGCAAGCACAGGGCTAAATTTAGCCTTGCATGTGGGAGCGATGCTTTTAGCCTT
TGTGGGGATGCTCGCGCTCATTAACGGGCTTTTAGGGGTTGTAGGGGGTTTTTTAGGCATGGAGCATTTGTCTTTAGGGT
TGATTTTAGGCACGCTCTTAAAACCCTTAGCCTTTATGTTAGGCATTCCTTGGAGCCAGGCCGGGATTGCCGGAGAAATC
ATAGGCATTAAAATCGCGCTCAATGAATTTGTGGGCTATATGCAGTTATTGCCTTATTTGGGCGATAACCCTCCTTTAAT
CTTGAGCGAGAAAACTAAAGCGATCATCACTTTTGCGTTGTGCGGGTTTGCTAATTTAAGCTCAGTCGCTATGCTCATTG
GAGGGCTTGGCAGTTTAGTGCCTAAAAAGAAGGATCTCATTGTAAGGCTTGCTTTAAAAGCGGTGCTTGTAGGCACGCTT
TCTAATTTCATGAGCGCGACTATCGCCGGGTTATTCATAGGGCTAAACGCTCATTAA

Upstream 100 bases:

>100_bases
TTGATTTAAACTTCATTTAATATCCGTTTAATCTTTTTTTTAGCAAAACTAAACTACAATAGCCTTGCATCTTTTAATTT
CTTGCATTAGGGATTTGACG

Downstream 100 bases:

>100_bases
AAGGACAAAACATGCAAAAAAGAGTGGTAATCTTATTATTGGATTCTTTTGGTATAGGGGCTAGCGAAGACGCTAAAGAT
TTTGGCGATTTGGGGGCGAA

Product: pyrimidine nucleoside transport protein (nupC)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MIFSSLFSVVGMAVLFLIAWVFSSNKRAINYRTIVSAFVIQVALGALALYVPLGREMLQGLASGIQSVISYGYEGVRFLF
GNLAPNAKGDQGIGGFVFAINVLAIIIFFASLISLLYYLKIMPLFINLIGGALQKCLGTSRAESMSAAANIFVAHTEAPL
VIKPYLKSMSDSEIFAVMCVGMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADVSIEKHV
NAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLLKPLAFMLGIPWSQAGIAGEI
IGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFALCGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTL
SNFMSATIAGLFIGLNAH

Sequences:

>Translated_418_residues
MIFSSLFSVVGMAVLFLIAWVFSSNKRAINYRTIVSAFVIQVALGALALYVPLGREMLQGLASGIQSVISYGYEGVRFLF
GNLAPNAKGDQGIGGFVFAINVLAIIIFFASLISLLYYLKIMPLFINLIGGALQKCLGTSRAESMSAAANIFVAHTEAPL
VIKPYLKSMSDSEIFAVMCVGMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADVSIEKHV
NAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLLKPLAFMLGIPWSQAGIAGEI
IGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFALCGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTL
SNFMSATIAGLFIGLNAH
>Mature_418_residues
MIFSSLFSVVGMAVLFLIAWVFSSNKRAINYRTIVSAFVIQVALGALALYVPLGREMLQGLASGIQSVISYGYEGVRFLF
GNLAPNAKGDQGIGGFVFAINVLAIIIFFASLISLLYYLKIMPLFINLIGGALQKCLGTSRAESMSAAANIFVAHTEAPL
VIKPYLKSMSDSEIFAVMCVGMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADVSIEKHV
NAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLLKPLAFMLGIPWSQAGIAGEI
IGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFALCGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTL
SNFMSATIAGLFIGLNAH

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI227116277, Length=415, Percent_Identity=35.1807228915663, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI42542381, Length=423, Percent_Identity=34.7517730496454, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI11545853, Length=379, Percent_Identity=33.7730870712401, Blast_Score=226, Evalue=4e-59,
Organism=Escherichia coli, GI1788485, Length=412, Percent_Identity=44.4174757281553, Blast_Score=321, Evalue=5e-89,
Organism=Escherichia coli, GI1788488, Length=412, Percent_Identity=44.9029126213592, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1788737, Length=405, Percent_Identity=27.6543209876543, Blast_Score=154, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17560276, Length=399, Percent_Identity=31.5789473684211, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71991794, Length=404, Percent_Identity=31.9306930693069, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI25146537, Length=226, Percent_Identity=30.0884955752212, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI45552517, Length=413, Percent_Identity=34.8668280871671, Blast_Score=255, Evalue=3e-68,
Organism=Drosophila melanogaster, GI19921868, Length=413, Percent_Identity=34.8668280871671, Blast_Score=255, Evalue=3e-68,
Organism=Drosophila melanogaster, GI45552519, Length=413, Percent_Identity=34.8668280871671, Blast_Score=255, Evalue=3e-68,
Organism=Drosophila melanogaster, GI281360430, Length=408, Percent_Identity=33.0882352941176, Blast_Score=223, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43808; Mature: 43808

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSSLFSVVGMAVLFLIAWVFSSNKRAINYRTIVSAFVIQVALGALALYVPLGREMLQG
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LASGIQSVISYGYEGVRFLFGNLAPNAKGDQGIGGFVFAINVLAIIIFFASLISLLYYLK
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMPLFINLIGGALQKCLGTSRAESMSAAANIFVAHTEAPLVIKPYLKSMSDSEIFAVMCV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCEEEHHHHHCCCCCHHHHHHHH
GMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADVSIEKHV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHH
NAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLAFMLGIPWSQAGIAGEIIGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFAL
HHHHHHHCCCCCCCCCCEEHEEHEEEHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
CGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTLSNFMSATIAGLFIGLNAH
HHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIFSSLFSVVGMAVLFLIAWVFSSNKRAINYRTIVSAFVIQVALGALALYVPLGREMLQG
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LASGIQSVISYGYEGVRFLFGNLAPNAKGDQGIGGFVFAINVLAIIIFFASLISLLYYLK
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMPLFINLIGGALQKCLGTSRAESMSAAANIFVAHTEAPLVIKPYLKSMSDSEIFAVMCV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCEEEHHHHHCCCCCHHHHHHHH
GMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADVSIEKHV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHH
NAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLAFMLGIPWSQAGIAGEIIGIKIALNEFVGYMQLLPYLGDNPPLILSEKTKAIITFAL
HHHHHHHCCCCCCCCCCEEHEEHEEEHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
CGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTLSNFMSATIAGLFIGLNAH
HHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]