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Identifier: 15645792

GI number: 15645792

Start: 1245964

End: 1246665

Strand: Reverse

Name: Not Available

Synonym: HP1178

Alternate gene names: 15645792

Gene position: 1246665-1245964 (Counterclockwise)

Preceding gene: 15645793

Following gene: 15645791

Centisome position: 74.75

GC content: 42.45

Gene sequence:

>702_bases
ATGACCCCTCACATCAACGCCAAAATCGGCGATTTTTATCCTCAATGCCTTTTATGCGGCGATCCCTTAAGGGTGAGCTA
CATTGCAAAAAAATTCTTACAAGACGCCAAAGAGATCACGAATGTGCGTAACATGCTAGGCTTTAGCGGGAAGTATAAGG
GTAGGGGGATTTCTTTAATGGGGCATGGCATGGGCATTGCGTCATGCACGATTTATGTAACCGAACTCATTAAAACCTAT
CAGGTTAAAGAGCTTTTAAGGATTGGCACTTGCGGGGCGATTAGCCCAAAAGTTGGCCTGAAAGACATTATCATGGCGAC
GGGGGCTTCAACGGATTCTAAAACCAATCGGGTGCGTTTTTTAAACCACGATTTGAGCGCAACGCCTGATTTTGAATTGA
GTTTAAGAGCGTATCAAACAGCAAAGCGTTTGGGTATTGATTTGAAAGTGGGCAATGTTTTTTCAAGCGATTTTTTCTAT
TCTTTTGAAACGCATGCCTTTGATTTAATGGCTAAATACAACCACTTGGCTATTGAAATGGAAGCGGCGGGGTTATACGC
CACGGCGATGGAACTAAACGCTAAGGCTTTATGCTTATGCTCAGTCTCAGATCACTTAATCACTAAAGAAGCCTTAAGCC
CTAAAGAAAGGGTAGAAAGCTTTGATAACATGATAATTTTGGCTTTGGAGATGATGAGTTAG

Upstream 100 bases:

>100_bases
AGAGCGAGTCGTTTGCGGATATTGGGCAAAGTATCGCTCACTTTTTGGGATTAAGCCCCCTAGATTATGGCAAAAACTTA
TTAAACTTTAAAGGACAACC

Downstream 100 bases:

>100_bases
CCTTTTTTGCCCCCATAAGTTAAGGATAAAATTTAAAGGAAAACCCTTAAAGCTAAAAGCCTTAAGGGAACTTTGGAAAA
ACTAAAGCTATCATTTTACA

Product: purine-nucleoside phosphorylase (deoD)

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTY
QVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFY
SFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS

Sequences:

>Translated_233_residues
MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTY
QVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFY
SFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS
>Mature_232_residues
TPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTYQ
VKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYS
FETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=229, Percent_Identity=55.4585152838428, Blast_Score=280, Evalue=8e-77,
Organism=Escherichia coli, GI1790265, Length=190, Percent_Identity=27.8947368421053, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25786; Mature: 25655

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLM
CCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
GHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCCCCCCEEEE
LNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAKYNHLAIEM
EECCCCCCCCCEEEHHHHHHHHHHCCEEEECCEECCCEEEEEHHHHHHHHHHCCEEEEEE
EAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS
ECCCEEEEEEECCCCEEEEEECCCHHHHHHHCCHHHHHHHHCCEEEEEEEECC
>Mature Secondary Structure 
TPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLM
CCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
GHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCCCCCCEEEE
LNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAKYNHLAIEM
EECCCCCCCCCEEEHHHHHHHHHHCCEEEECCEECCCEEEEEHHHHHHHHHHCCEEEEEE
EAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS
ECCCEEEEEEECCCCEEEEEECCCHHHHHHHCCHHHHHHHHCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA