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Identifier: 15645658

GI number: 15645658

Start: 1105773

End: 1106885

Strand: Reverse

Name: Not Available

Synonym: HP1044

Alternate gene names: NA

Gene position: 1106885-1105773 (Counterclockwise)

Preceding gene: 15645660

Following gene: 15645657

Centisome position: 66.37

GC content: 37.2

Gene sequence:

>1113_bases
ATGCTGATCTCCATAGCGTTTTTATTGGTTTTATATCTTTTGAATTATAGTTCTTTCAGGATGTTGAAATCGTTTTTAAC
CTTAAAGAAAATCTCTCAATACGCTTATTTATGGTTTTTTATCCTTTTGAGCATAGGCGAGGCGGCTTTTGTTTTTTATA
GAAATATTATGCCTAGCCATTTGTTTGTTTTGACTTCAGCGTGTTCGTTTGTGTCTTTTATTATTTTTATCCTTTCTTTA
AGTTTTTACGGGTTTTCCTATTCCATAGAAAAAATAGATTTTTTGCATTCAAGGCGTAAAAGTTTAAAAAACTTTTTAAA
ATTGGGGTTTTATCTGGCGTTATTAGGGTATTTTTGGCGTGGGTTTTATGAAGGGTTGGCCCGCCCTAAAATCAAAGAAA
CCCCTATTTATTTGGATAAGCTGGATAAAGAATTAAAGATTATTTTACTCACAGACATGCATGTGGGGAGTTTGTTGCAA
AAAGATTTTGTTGATTACATTGTAGAAGAAGTCAATCAAAAAGAAGTGGATATGGTGCTGATTGGGGGGGATTTAGTGGA
TGAAAGCATTGAAAAAGTCAAATCTTTTTTACTGCCTTTAAACAACCTTAAAAGCACGCATGGCACTTTTTATGTGCCAG
GAAATCATGAGTATTATCATGGCATAGAGCCGATTTTATCGTTTCTTGACACGCTTAATTTGACGATTTTAGGGAATGAG
TGCGTGCATTTAGGGGGGATCAATTTGTGCGGCGTGTATGATTATTTCGCAAGGAAGCGTCAAAATTTTGCCCCTGATAT
TGACAAAGCTTTAAAAAAGCGCAATGAGAGTAAGCCCACGATCCTTTTGGCCCACCAACCTAAACAAATTAGAAGCCTCA
AAGAAAGCCACTCTGTAGATTTAGTCCTTTCAGGGCATACCCATGCAGGGCAAATCTTTCCCTTTAGCCTTTTAGTCAAG
TTGGCGCAAACCTATTTACATGGTTTATACAAGCACAGCCCCACCACTCAAATTTATGTGAGCAGTGGGGCAGGGTATTG
GGGGATTCCTTTAAGGTTTTTAGCCCCTAGCGAGATCGCATACCTTAGGCTTTTACCTAAAAATCAAGCTTAG

Upstream 100 bases:

>100_bases
TTGAGACTGATAAAAAAGGAAATAGCACGATGAAACCTAAAGGGGATATTAGCGTTAATATGCTAATATAGTAGAACATT
ATGACTACAAAAAGGGTGAT

Downstream 100 bases:

>100_bases
TTAAACAAAATCTTAAAATCTTAATCGTAATCAAGCGGTTAAAAATAAGAACTAAACAAGGATTAAAAAACAACCGCCAA
GACAAAGGGAAAGGAGGGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MLISIAFLLVLYLLNYSSFRMLKSFLTLKKISQYAYLWFFILLSIGEAAFVFYRNIMPSHLFVLTSACSFVSFIIFILSL
SFYGFSYSIEKIDFLHSRRKSLKNFLKLGFYLALLGYFWRGFYEGLARPKIKETPIYLDKLDKELKIILLTDMHVGSLLQ
KDFVDYIVEEVNQKEVDMVLIGGDLVDESIEKVKSFLLPLNNLKSTHGTFYVPGNHEYYHGIEPILSFLDTLNLTILGNE
CVHLGGINLCGVYDYFARKRQNFAPDIDKALKKRNESKPTILLAHQPKQIRSLKESHSVDLVLSGHTHAGQIFPFSLLVK
LAQTYLHGLYKHSPTTQIYVSSGAGYWGIPLRFLAPSEIAYLRLLPKNQA

Sequences:

>Translated_370_residues
MLISIAFLLVLYLLNYSSFRMLKSFLTLKKISQYAYLWFFILLSIGEAAFVFYRNIMPSHLFVLTSACSFVSFIIFILSL
SFYGFSYSIEKIDFLHSRRKSLKNFLKLGFYLALLGYFWRGFYEGLARPKIKETPIYLDKLDKELKIILLTDMHVGSLLQ
KDFVDYIVEEVNQKEVDMVLIGGDLVDESIEKVKSFLLPLNNLKSTHGTFYVPGNHEYYHGIEPILSFLDTLNLTILGNE
CVHLGGINLCGVYDYFARKRQNFAPDIDKALKKRNESKPTILLAHQPKQIRSLKESHSVDLVLSGHTHAGQIFPFSLLVK
LAQTYLHGLYKHSPTTQIYVSSGAGYWGIPLRFLAPSEIAYLRLLPKNQA
>Mature_370_residues
MLISIAFLLVLYLLNYSSFRMLKSFLTLKKISQYAYLWFFILLSIGEAAFVFYRNIMPSHLFVLTSACSFVSFIIFILSL
SFYGFSYSIEKIDFLHSRRKSLKNFLKLGFYLALLGYFWRGFYEGLARPKIKETPIYLDKLDKELKIILLTDMHVGSLLQ
KDFVDYIVEEVNQKEVDMVLIGGDLVDESIEKVKSFLLPLNNLKSTHGTFYVPGNHEYYHGIEPILSFLDTLNLTILGNE
CVHLGGINLCGVYDYFARKRQNFAPDIDKALKKRNESKPTILLAHQPKQIRSLKESHSVDLVLSGHTHAGQIFPFSLLVK
LAQTYLHGLYKHSPTTQIYVSSGAGYWGIPLRFLAPSEIAYLRLLPKNQA

Specific function: Unknown

COG id: COG1408

COG function: function code R; Predicted phosphohydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallophosphoesterase superfamily

Homologues:

Organism=Homo sapiens, GI210031196, Length=270, Percent_Identity=34.8148148148148, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI210031210, Length=294, Percent_Identity=33.6734693877551, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI115535030, Length=368, Percent_Identity=30.7065217391304, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI115535028, Length=368, Percent_Identity=30.7065217391304, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71996034, Length=358, Percent_Identity=29.0502793296089, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1044_HELPY (O25685)

Other databases:

- EMBL:   AE000511
- PIR:   D64650
- RefSeq:   NP_207834.1
- ProteinModelPortal:   O25685
- GeneID:   899579
- GenomeReviews:   AE000511_GR
- KEGG:   hpy:HP1044
- NMPDR:   fig|85962.1.peg.1031
- TIGR:   HP_1044
- HOGENOM:   HBG728202
- OMA:   YEGLARP
- ProtClustDB:   CLSK872352
- InterPro:   IPR004843

Pfam domain/function: PF00149 Metallophos

EC number: NA

Molecular weight: Translated: 42457; Mature: 42457

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISIAFLLVLYLLNYSSFRMLKSFLTLKKISQYAYLWFFILLSIGEAAFVFYRNIMPSH
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVLTSACSFVSFIIFILSLSFYGFSYSIEKIDFLHSRRKSLKNFLKLGFYLALLGYFWR
HHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFYEGLARPKIKETPIYLDKLDKELKIILLTDMHVGSLLQKDFVDYIVEEVNQKEVDMVL
HHHHHHCCCCCCCCCCHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEE
IGGDLVDESIEKVKSFLLPLNNLKSTHGTFYVPGNHEYYHGIEPILSFLDTLNLTILGNE
ECCHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCHHCCHHHHHHHHHHCCEEEECCC
CVHLGGINLCGVYDYFARKRQNFAPDIDKALKKRNESKPTILLAHQPKQIRSLKESHSVD
EEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCEE
LVLSGHTHAGQIFPFSLLVKLAQTYLHGLYKHSPTTQIYVSSGAGYWGIPLRFLAPSEIA
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCEEEECCCCEE
YLRLLPKNQA
EEEECCCCCC
>Mature Secondary Structure
MLISIAFLLVLYLLNYSSFRMLKSFLTLKKISQYAYLWFFILLSIGEAAFVFYRNIMPSH
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVLTSACSFVSFIIFILSLSFYGFSYSIEKIDFLHSRRKSLKNFLKLGFYLALLGYFWR
HHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFYEGLARPKIKETPIYLDKLDKELKIILLTDMHVGSLLQKDFVDYIVEEVNQKEVDMVL
HHHHHHCCCCCCCCCCHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEE
IGGDLVDESIEKVKSFLLPLNNLKSTHGTFYVPGNHEYYHGIEPILSFLDTLNLTILGNE
ECCHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCHHCCHHHHHHHHHHCCEEEECCC
CVHLGGINLCGVYDYFARKRQNFAPDIDKALKKRNESKPTILLAHQPKQIRSLKESHSVD
EEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCEE
LVLSGHTHAGQIFPFSLLVKLAQTYLHGLYKHSPTTQIYVSSGAGYWGIPLRFLAPSEIA
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCEEEECCCCEE
YLRLLPKNQA
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9252185