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Identifier: 15645532

GI number: 15645532

Start: 972716

End: 973465

Strand: Reverse

Name: Not Available

Synonym: HP0916

Alternate gene names: 15645532

Gene position: 973465-972716 (Counterclockwise)

Preceding gene: 15645534

Following gene: 15645531

Centisome position: 58.37

GC content: 41.87

Gene sequence:

>750_bases
ATGAATGACAAGCGTTTTAGAAAATATTGTAGTTTTTCTATTTTTTTGTCCTTATTAGGAACGTTTGAATTAGAGGCTAA
AGAAGAAGAAGAAAAAGAAGAAAGAAAGACAGAAAGGAAAAAAGAAAAGAACGCCCAACACACTCTAGGCAAGGTTACCA
CTCAAGCGGCTAAAATCTTTAACTACAACAACCAGACAACCATTTCAAGTAAGGAATTAGAAAGAAGGCAAGCCAACCAA
ATCAGCGACATGTTTAGAAGAAACCCTAATATCAATGTGGGCGGTGGTGCGGTGATAGCGCAAAAAATTTATGTGCGCGG
TATTGAAGACAGATTGGCTCGGGTTACGGTGGATGGGGCGGCGCAAATGGGTGCAAGCTATGGGCATCAAGGCAATACGA
TCATTGACCCTGGAATGCTTAAAAGCGTGGTGGTTACTAAAGGGGCGGCTCAAGCGAGCGCGGGGCCTATGGCTTTGATT
GGCGCGATTAAAATGGAGACTAAAAGTGCTAGCGATTTTATCCCTAAAGGTAAAGACTACGCCATAAGTGGGGCTGCCAC
TTTTTTAACCAACTTTGGGGATCGAGAAACCGTGATGGGCGCTTATCGTCATAATCATTTTGATGCGCTTTTGTATTACA
CGCATCAAAATATTTTTTACTATCGTGATGGGGATAATGCTACAAAAGATCTCTTTAGACCTAAAGCGGAGAATAAAGTT
ACAGAAGTCCTAGCGAGCAAAACAATGTGA

Upstream 100 bases:

>100_bases
GTAACCGAGAAAAATCTTTCTCTAAAAATAATACTTTTTTAGTTATAATAACAATTTTGTTTTTTCAAAAACAATAATTA
CTATATTTAGGATTTTAAGA

Downstream 100 bases:

>100_bases
TGGCTAAGATCAATGGTTATTTGAGCGAAAGGGATATTTTAACGCTCAGTTATAACATGACCAGAGACAACGCTAACCGC
CCTTTAAGAGCGAATTTTAC

Product: iron-regulated outer membrane protein (frpB)

Products: NA

Alternate protein names: Brucella heme uptake protein A [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MNDKRFRKYCSFSIFLSLLGTFELEAKEEEEKEERKTERKKEKNAQHTLGKVTTQAAKIFNYNNQTTISSKELERRQANQ
ISDMFRRNPNINVGGGAVIAQKIYVRGIEDRLARVTVDGAAQMGASYGHQGNTIIDPGMLKSVVVTKGAAQASAGPMALI
GAIKMETKSASDFIPKGKDYAISGAATFLTNFGDRETVMGAYRHNHFDALLYYTHQNIFYYRDGDNATKDLFRPKAENKV
TEVLASKTM

Sequences:

>Translated_249_residues
MNDKRFRKYCSFSIFLSLLGTFELEAKEEEEKEERKTERKKEKNAQHTLGKVTTQAAKIFNYNNQTTISSKELERRQANQ
ISDMFRRNPNINVGGGAVIAQKIYVRGIEDRLARVTVDGAAQMGASYGHQGNTIIDPGMLKSVVVTKGAAQASAGPMALI
GAIKMETKSASDFIPKGKDYAISGAATFLTNFGDRETVMGAYRHNHFDALLYYTHQNIFYYRDGDNATKDLFRPKAENKV
TEVLASKTM
>Mature_249_residues
MNDKRFRKYCSFSIFLSLLGTFELEAKEEEEKEERKTERKKEKNAQHTLGKVTTQAAKIFNYNNQTTISSKELERRQANQ
ISDMFRRNPNINVGGGAVIAQKIYVRGIEDRLARVTVDGAAQMGASYGHQGNTIIDPGMLKSVVVTKGAAQASAGPMALI
GAIKMETKSASDFIPKGKDYAISGAATFLTNFGDRETVMGAYRHNHFDALLYYTHQNIFYYRDGDNATKDLFRPKAENKV
TEVLASKTM

Specific function: Heme transporter playing an important role in stationary-phase iron acquisition and required for maintenance of chronic infection in mice [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 27827; Mature: 27827

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKRFRKYCSFSIFLSLLGTFELEAKEEEEKEERKTERKKEKNAQHTLGKVTTQAAKIF
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NYNNQTTISSKELERRQANQISDMFRRNPNINVGGGAVIAQKIYVRGIEDRLARVTVDGA
CCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHEEEECCH
AQMGASYGHQGNTIIDPGMLKSVVVTKGAAQASAGPMALIGAIKMETKSASDFIPKGKDY
HHHHHHCCCCCCEEECCHHHHHHHHHCCCCCCCCCCEEEHHHHHCCCCCCHHCCCCCCCE
AISGAATFLTNFGDRETVMGAYRHNHFDALLYYTHQNIFYYRDGDNATKDLFRPKAENKV
EECHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEECEEEEEECCCCCHHHHHCCCHHHHH
TEVLASKTM
HHHHHHCCC
>Mature Secondary Structure
MNDKRFRKYCSFSIFLSLLGTFELEAKEEEEKEERKTERKKEKNAQHTLGKVTTQAAKIF
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NYNNQTTISSKELERRQANQISDMFRRNPNINVGGGAVIAQKIYVRGIEDRLARVTVDGA
CCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHEEEECCH
AQMGASYGHQGNTIIDPGMLKSVVVTKGAAQASAGPMALIGAIKMETKSASDFIPKGKDY
HHHHHHCCCCCCEEECCHHHHHHHHHCCCCCCCCCCEEEHHHHHCCCCCCHHCCCCCCCE
AISGAATFLTNFGDRETVMGAYRHNHFDALLYYTHQNIFYYRDGDNATKDLFRPKAENKV
EECHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEECEEEEEECCCCCHHHHHCCCHHHHH
TEVLASKTM
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA