Click here to switch to the map view.

The map label for this gene is coaE

Identifier: 15645450

GI number: 15645450

Start: 883640

End: 884230

Strand: Reverse

Name: coaE

Synonym: HP0831

Alternate gene names: 15645450

Gene position: 884230-883640 (Counterclockwise)

Preceding gene: 15645451

Following gene: 15645449

Centisome position: 53.02

GC content: 37.06

Gene sequence:

>591_bases
ATGGTTTTAAAAAACGCTATCGCTCTCACAGGGGGGATAGGCACCGGTAAAAGCACCACCATTAAAATATTGGAATCGCA
AGGTTATAAGATCCTAGATGCGGATAAGATCGCCCACCAATTATTGCAAGAGCATCGGTTTAAAATCGCCCAACATTTTG
GATCAGATATTTTAGAAAAAGATATTTTAAACAGAAAAAAACTTGGTGCGATCGTGTTTCAAGATGCTCATGAGTTAAAA
TGGCTAGAGGATTTTTTACACCCCTTAATCCGTGAACACATGCTTAAAAAAGCCTATGAATTAGAAAAGAATCATCAAGC
GTATTTTTTAGACATCCCTTTATTTTTTGAAGTTGGGGGTAAAAAATGCTATCCTGTGAGTAAAGTGGTTTTAGTCTATG
CGTCTAGGGCTTTACAAATTGAGCGCCTTTTAGAGAGAGACAAACTCAAAGAGGCTGAAATCTTGCAGCGCTTAGCTTGT
CAAATGGATATAGAGCAAAAACGCGCCATGAGCGATTATATTATAGACAACAGCTCCAGTTTAAAAGATTTAAATAAGCA
GGTTGAACGCTTTTTAAAAACGCTCTTATAA

Upstream 100 bases:

>100_bases
CTAACAAGCGTGAGATACTATAACGAAGACATTCATAGGGCTGCATTCGCTTTGCCTAAAAATTTACAAGAAGTCTTTAA
AGACAATATCAAATCTTAAA

Downstream 100 bases:

>100_bases
GCTCGTTTTATCTCTAAGCATGTTAAACTACCATTAAATTTTTTGTAAGGCTAAAAACATGATCACTTTAAAACAAGCCC
TTTCTTTATCCCAAGATGAA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MVLKNAIALTGGIGTGKSTTIKILESQGYKILDADKIAHQLLQEHRFKIAQHFGSDILEKDILNRKKLGAIVFQDAHELK
WLEDFLHPLIREHMLKKAYELEKNHQAYFLDIPLFFEVGGKKCYPVSKVVLVYASRALQIERLLERDKLKEAEILQRLAC
QMDIEQKRAMSDYIIDNSSSLKDLNKQVERFLKTLL

Sequences:

>Translated_196_residues
MVLKNAIALTGGIGTGKSTTIKILESQGYKILDADKIAHQLLQEHRFKIAQHFGSDILEKDILNRKKLGAIVFQDAHELK
WLEDFLHPLIREHMLKKAYELEKNHQAYFLDIPLFFEVGGKKCYPVSKVVLVYASRALQIERLLERDKLKEAEILQRLAC
QMDIEQKRAMSDYIIDNSSSLKDLNKQVERFLKTLL
>Mature_196_residues
MVLKNAIALTGGIGTGKSTTIKILESQGYKILDADKIAHQLLQEHRFKIAQHFGSDILEKDILNRKKLGAIVFQDAHELK
WLEDFLHPLIREHMLKKAYELEKNHQAYFLDIPLFFEVGGKKCYPVSKVVLVYASRALQIERLLERDKLKEAEILQRLAC
QMDIEQKRAMSDYIIDNSSSLKDLNKQVERFLKTLL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=189, Percent_Identity=32.8042328042328, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI191252795, Length=189, Percent_Identity=32.8042328042328, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI110227605, Length=192, Percent_Identity=30.7291666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227603, Length=192, Percent_Identity=30.7291666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227601, Length=192, Percent_Identity=30.7291666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227607, Length=192, Percent_Identity=30.7291666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI205277394, Length=192, Percent_Identity=30.7291666666667, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1786292, Length=189, Percent_Identity=31.2169312169312, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17554944, Length=197, Percent_Identity=29.9492385786802, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25143409, Length=196, Percent_Identity=29.5918367346939, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=201, Percent_Identity=38.8059701492537, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644728, Length=183, Percent_Identity=36.0655737704918, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24658602, Length=197, Percent_Identity=30.4568527918782, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22663; Mature: 22663

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLKNAIALTGGIGTGKSTTIKILESQGYKILDADKIAHQLLQEHRFKIAQHFGSDILEK
CCCCCHHHEECCCCCCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHCHHHHHH
DILNRKKLGAIVFQDAHELKWLEDFLHPLIREHMLKKAYELEKNHQAYFLDIPLFFEVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHEEECCC
KKCYPVSKVVLVYASRALQIERLLERDKLKEAEILQRLACQMDIEQKRAMSDYIIDNSSS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LKDLNKQVERFLKTLL
HHHHHHHHHHHHHHHC
>Mature Secondary Structure
MVLKNAIALTGGIGTGKSTTIKILESQGYKILDADKIAHQLLQEHRFKIAQHFGSDILEK
CCCCCHHHEECCCCCCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHCHHHHHH
DILNRKKLGAIVFQDAHELKWLEDFLHPLIREHMLKKAYELEKNHQAYFLDIPLFFEVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHEEECCC
KKCYPVSKVVLVYASRALQIERLLERDKLKEAEILQRLACQMDIEQKRAMSDYIIDNSSS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LKDLNKQVERFLKTLL
HHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]