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The map label for this gene is def

Identifier: 15645412

GI number: 15645412

Start: 850488

End: 851012

Strand: Reverse

Name: def

Synonym: HP0793

Alternate gene names: 15645412

Gene position: 851012-850488 (Counterclockwise)

Preceding gene: 15645413

Following gene: 15645411

Centisome position: 51.02

GC content: 40.57

Gene sequence:

>525_bases
ATGGCGTTATTAGAGATTATCCATTACCCTTCTAAAATCTTAAGAACGATTTCTAAAGAGGTCGTTTCTTTTGATTCAAA
ACTCCACCAACAGCTAGATGACATGCATGAGACTATGATCGCTAGTGAGGGGATAGGGTTAGCCGCTATTCAAGTGGGTT
TGCCTTTAAGAATGCTCATCATCAACCTCCCGCAAGAAGACGGCGTGCAACACAAAGAAGACTGCTTGGAAATCATTAAC
CCTAAGTTTATAGAAACTGGGGGATCAATGATGTATAGAGAAGGGTGCTTGTCTGTGCCGGGATTTTACGAAGAAGTGGA
GCGTTTTGAAAAGGTTAAGATAGAGTATCAAAACCGCTTCGCTGAAGTGAAAGTTTTAGAAGCGAGCGAGCTTTTAGCGG
TAGCCATTCAGCATGAGATCGATCACCTCAATGGCGTGTTATTCGTGGATAAATTATCCATTTTGAAGCGTAAGAAATTT
GAAAAAGAACTCAAAGAGCTGCAAAAAAAACAAAAACACGAGTAA

Upstream 100 bases:

>100_bases
ATCGCTAAAGACACGGACAGGGATTTTTATATGAGTGCTAAAGAAGCTAAAGAGTATGGCTTGATTGATAAAGTGTTACA
GAAAAACGTGAAGTGATTGC

Downstream 100 bases:

>100_bases
CAACCATGATTAACACGATGTTTTGCGCGACCATGCAAAGGGGAGTGGCGGAAATCGTGGCTGTGGAAGCGACTTTCACA
AGGGCTTTGCCGGCGTTTGT

Product: peptide deformylase

Products: NA

Alternate protein names: PDF; Polypeptide deformylase [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MALLEIIHYPSKILRTISKEVVSFDSKLHQQLDDMHETMIASEGIGLAAIQVGLPLRMLIINLPQEDGVQHKEDCLEIIN
PKFIETGGSMMYREGCLSVPGFYEEVERFEKVKIEYQNRFAEVKVLEASELLAVAIQHEIDHLNGVLFVDKLSILKRKKF
EKELKELQKKQKHE

Sequences:

>Translated_174_residues
MALLEIIHYPSKILRTISKEVVSFDSKLHQQLDDMHETMIASEGIGLAAIQVGLPLRMLIINLPQEDGVQHKEDCLEIIN
PKFIETGGSMMYREGCLSVPGFYEEVERFEKVKIEYQNRFAEVKVLEASELLAVAIQHEIDHLNGVLFVDKLSILKRKKF
EKELKELQKKQKHE
>Mature_173_residues
ALLEIIHYPSKILRTISKEVVSFDSKLHQQLDDMHETMIASEGIGLAAIQVGLPLRMLIINLPQEDGVQHKEDCLEIINP
KFIETGGSMMYREGCLSVPGFYEEVERFEKVKIEYQNRFAEVKVLEASELLAVAIQHEIDHLNGVLFVDKLSILKRKKFE
KELKELQKKQKHE

Specific function: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions

COG id: COG0242

COG function: function code J; N-formylmethionyl-tRNA deformylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polypeptide deformylase family [H]

Homologues:

Organism=Escherichia coli, GI1789682, Length=169, Percent_Identity=40.2366863905325, Blast_Score=124, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24645728, Length=157, Percent_Identity=31.2101910828025, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000181 [H]

Pfam domain/function: PF01327 Pep_deformylase [H]

EC number: =3.5.1.88 [H]

Molecular weight: Translated: 20058; Mature: 19927

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLEIIHYPSKILRTISKEVVSFDSKLHQQLDDMHETMIASEGIGLAAIQVGLPLRMLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHE
INLPQEDGVQHKEDCLEIINPKFIETGGSMMYREGCLSVPGFYEEVERFEKVKIEYQNRF
EECCCCCCCCHHHHHHHHHCCHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
AEVKVLEASELLAVAIQHEIDHLNGVLFVDKLSILKRKKFEKELKELQKKQKHE
HHHHEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALLEIIHYPSKILRTISKEVVSFDSKLHQQLDDMHETMIASEGIGLAAIQVGLPLRMLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHE
INLPQEDGVQHKEDCLEIINPKFIETGGSMMYREGCLSVPGFYEEVERFEKVKIEYQNRF
EECCCCCCCCHHHHHHHHHCCHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
AEVKVLEASELLAVAIQHEIDHLNGVLFVDKLSILKRKKFEKELKELQKKQKHE
HHHHEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA