Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15645224

GI number: 15645224

Start: 633964

End: 635265

Strand: Reverse

Name: Not Available

Synonym: HP0599

Alternate gene names: 15645224

Gene position: 635265-633964 (Counterclockwise)

Preceding gene: 15645225

Following gene: 15645223

Centisome position: 38.09

GC content: 38.4

Gene sequence:

>1302_bases
ATGTTTGGGAATAAGCAGTTGCAACTTCAAATCAGTCAGAAAGATTCTGAGATTGCGGAGTTAAAAAAAGAAGTCAATCT
TTATCAAAGCCTTTTAAATTTGTGCTTGCATGAGGGTTTTGTAGGTATTAAAAACAATAAAGTCGTTTTTAAAAGTGGGA
ATCTTGCAAGCTTGAACAATTTAGAAGAACAAAGCGTTCATTTTAAAGAAAATGCAGAGAGCGTTAATTTACAAGGGGTT
TCTTATTCTTTAAAAAGCCAAAATATTGATGGCGTGCAGTATTTTTCATTGGCTAAAAACACAAGTTGTGTGGGGGAATA
CCATAAAAATGATTTGTTTAAGACTTTTTGCGCGAGCTTAAAAGAAGGCTTAGAGAACGCGCAAGAAAGCATGCAGTATT
TCCATCAAGAAACCGGTGCTCTTTTAAATGCAGCTAAAAATGGCGAAGCGCATTCTACTGAAGGATTGGGGACGGTTAAT
AAAACGGGGCAAGACATTGAATCGCTTTATGAAAAGATGCAAAACGCCACTTCGCTAGCGGACTCTCTCAACCAACGGAG
CAATGAAATCACTCAAGTCATTTCTTTGATTGATGATATTGCAGAACAAACCAATCTATTAGCCCTAAATGCCGCTATTG
AGGCCGCGCGAGCGGGCGAGCATGGGAGAGGGTTTGCGGTGGTGGCTGATGAGGTGAGAAAACTCGCTGAAAAAACCCAA
AAAGCCACTAAAGAAATCGCTGTTGTCGTTAAAAGCATGCAACAAGAAGCGAACGATATTCAAACCAATACCCACGATAT
TAATTCTATTGTAAGCTCTATTAAGGGCGATGTGGAAGAGCTTAAATCCACCGTAAAAAATAACATGATTGTTGCGCAAG
CGGCAAAATACACCATCTACAATATCAATAACCGGGTGTTTTGCGGTTTGGCCAAACTTGATCATGTGGTCTTTAAAAAC
AATCTTTATGGCATGGTTTTTGGTCTCAATTCCTTTGATATTACCAGCCATAAGAATTGCCGTTTAGGCAAATGGTATTA
TGAGGGCGCGGGCAAAGAGAATTTTTCCAACACTTCAGGCTATAGAGCTTTAGAAAGCCACCATGCAAGCGTGCATGCTG
AAGCTAATGATTTGGTTAAAGCCGTTCAAGAAGACCACATTACCGATTCAAAATACCTAGAGCATAAAGTGCATTTAATG
GAAGATAGTGCTAAACATGTTAGAGAAAATATTGATAAGATGTTTTACGAAAAACAAGATGAACTCAATAAAATCATTGA
AAAAATTCAAAAAGGCGAATGA

Upstream 100 bases:

>100_bases
ACGAATTGTTTTTGAAGCAGCAATACTAACGAGCGCTTAAAATGTTTGGTAATTTTGGGTATAATCCCAAAAGATTCAAA
TTTAAATAAGGAATGCCATA

Downstream 100 bases:

>100_bases
TTTTATTCAATGAAGTGTTTTGATGTTTTCTAAATCTTTAGAAGCCCTACACCATGCCAAACGCTACCGCAAAAGAGAGT
TGTTTGACCCTTTATTAAAG

Product: hemolysin secretion protein precursor (hylB)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MFGNKQLQLQISQKDSEIAELKKEVNLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLNNLEEQSVHFKENAESVNLQGV
SYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASLKEGLENAQESMQYFHQETGALLNAAKNGEAHSTEGLGTVN
KTGQDIESLYEKMQNATSLADSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQ
KATKEIAVVVKSMQQEANDIQTNTHDINSIVSSIKGDVEELKSTVKNNMIVAQAAKYTIYNINNRVFCGLAKLDHVVFKN
NLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSGYRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLM
EDSAKHVRENIDKMFYEKQDELNKIIEKIQKGE

Sequences:

>Translated_433_residues
MFGNKQLQLQISQKDSEIAELKKEVNLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLNNLEEQSVHFKENAESVNLQGV
SYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASLKEGLENAQESMQYFHQETGALLNAAKNGEAHSTEGLGTVN
KTGQDIESLYEKMQNATSLADSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQ
KATKEIAVVVKSMQQEANDIQTNTHDINSIVSSIKGDVEELKSTVKNNMIVAQAAKYTIYNINNRVFCGLAKLDHVVFKN
NLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSGYRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLM
EDSAKHVRENIDKMFYEKQDELNKIIEKIQKGE
>Mature_433_residues
MFGNKQLQLQISQKDSEIAELKKEVNLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLNNLEEQSVHFKENAESVNLQGV
SYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASLKEGLENAQESMQYFHQETGALLNAAKNGEAHSTEGLGTVN
KTGQDIESLYEKMQNATSLADSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQ
KATKEIAVVVKSMQQEANDIQTNTHDINSIVSSIKGDVEELKSTVKNNMIVAQAAKYTIYNINNRVFCGLAKLDHVVFKN
NLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSGYRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLM
EDSAKHVRENIDKMFYEKQDELNKIIEKIQKGE

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=89, Percent_Identity=48.314606741573, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788195, Length=73, Percent_Identity=60.2739726027397, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789453, Length=203, Percent_Identity=32.512315270936, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788194, Length=90, Percent_Identity=53.3333333333333, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787690, Length=84, Percent_Identity=48.8095238095238, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 48362; Mature: 48362

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGNKQLQLQISQKDSEIAELKKEVNLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLNN
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCHHHCC
LEEQSVHFKENAESVNLQGVSYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASL
CHHHHHHHHCCCCEEEEECCEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KEGLENAQESMQYFHQETGALLNAAKNGEAHSTEGLGTVNKTGQDIESLYEKMQNATSLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQ
HHHHHHHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHH
KATKEIAVVVKSMQQEANDIQTNTHDINSIVSSIKGDVEELKSTVKNNMIVAQAAKYTIY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECEEEEE
NINNRVFCGLAKLDHVVFKNNLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSG
ECCCEEEEEHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCC
YRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLMEDSAKHVRENIDKMFYEKQD
HHHHHHHCCCEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELNKIIEKIQKGE
HHHHHHHHHHCCC
>Mature Secondary Structure
MFGNKQLQLQISQKDSEIAELKKEVNLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLNN
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCHHHCC
LEEQSVHFKENAESVNLQGVSYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASL
CHHHHHHHHCCCCEEEEECCEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KEGLENAQESMQYFHQETGALLNAAKNGEAHSTEGLGTVNKTGQDIESLYEKMQNATSLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQ
HHHHHHHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHH
KATKEIAVVVKSMQQEANDIQTNTHDINSIVSSIKGDVEELKSTVKNNMIVAQAAKYTIY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECEEEEE
NINNRVFCGLAKLDHVVFKNNLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSG
ECCCEEEEEHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCC
YRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLMEDSAKHVRENIDKMFYEKQD
HHHHHHHCCCEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELNKIIEKIQKGE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1548224 [H]