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The map label for this gene is ychF

Identifier: 15645194

GI number: 15645194

Start: 601079

End: 602179

Strand: Reverse

Name: ychF

Synonym: HP0569

Alternate gene names: 15645194

Gene position: 602179-601079 (Counterclockwise)

Preceding gene: 15645195

Following gene: 15645193

Centisome position: 36.1

GC content: 41.14

Gene sequence:

>1101_bases
ATGGGCTTGTCTGTAGGCATTGTGGGTTTGCCTAATGTGGGCAAATCCAGCACCTTTAACGCGCTCACTAAAACCCAAAA
CGCCCAAAGCGCGAACTACCCTTTTTGCACCATTGAACCCAATAAAGCCATTGTGAATGTGCCTGATAGGCGGCTTGATG
CGTTGGCTCAAATCGTAAAGCCTGAACGCATTTTGCATTCTGTGGTGGAATTTGTGGATATTGCCGGATTGATTAAGGGA
GCGAGCAAGGGGGAGGGTTTAGGCAATCAGTTTTTAGCCAATATCAAGGAATGCGAAGTGATCTTGCAAGTGGTGCGTTG
TTTTGAAGATGATAATATCACGCATGTGAACGACAAGATTGATCCTTTGAATGATATAGAAACTATTGAATTGGAGTTGA
TTTTAGCGGATATTGCCGCTTTAGACAAAAGGATCGATCGCTTGCAAAAAGCCTTAAAAAGCTCAAAAGACGCTAAAAAT
CTTTTAGAATGCGCTTTGAGTTTAAAAACGCATTTAGAAGAATTAAAACCGGCGAAAACTTTCCCCTTGAATACAAGCGA
GGCTTTTTTGGAGTTGGACAAGGAATTGCGTTTTTTATCTCATAAAAAAATGATCTATGTCGCTAATGTGGGCGAAGAAG
ATTTAAACGCGCTCAATGAGCATGCCAAAAAAGTCAAAAACCATGCGAAAGAACAAAATAGCGAGTTTGTTGCCTTGTGT
GCTAAATTAGAAGAAGAAATGGTTTCTATGAGTGGAGATGAAGTCAAAGAATTTTTGCAAAGTTTGGGCGTAGAAGAAAG
CGGGCTAGAAAAGACCATTCGTTTGAGTTTTAAGGAATTAGGTTTGATCAATTATTTTACCGCTGGAGTCAAGGAAGTGC
GATCATGGACGATTAAAAAAGGCTCTAGTGCGCCTGTGGCTGCTGGGGTGATCCATAAGGATTTTGAAAAAGGCTTCATT
AGAGCTGAAACCATCAGTTATGATGACTTTATCGCTTATAAGGGCGAAGCCGGAGCGAAAGAAAAGGGAGCGTTACGCAT
TGAAGGTAAGGATTATATCGTTCAAGATGGCGATGTGTTGCATTTTCGCTTCAATATCTAG

Upstream 100 bases:

>100_bases
TATGTGGAAAAAGAATGGGATGTGAATAGCTTTGGAGCGAGTGGGGCTGGCGTGAGAGCTTGCACAGCTTTTGTGGAAGA
GCTTTTGAAAAAGGCTTGAA

Downstream 100 bases:

>100_bases
TCTGTCTTATTACTAATTTCTCATAAGAATTGACACCCAACAAGAAACTTTTTAAAAAAATCTATGTAGAATTAAGCGAT
ATTTGCGGGTTGCAATGCAG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MGLSVGIVGLPNVGKSSTFNALTKTQNAQSANYPFCTIEPNKAIVNVPDRRLDALAQIVKPERILHSVVEFVDIAGLIKG
ASKGEGLGNQFLANIKECEVILQVVRCFEDDNITHVNDKIDPLNDIETIELELILADIAALDKRIDRLQKALKSSKDAKN
LLECALSLKTHLEELKPAKTFPLNTSEAFLELDKELRFLSHKKMIYVANVGEEDLNALNEHAKKVKNHAKEQNSEFVALC
AKLEEEMVSMSGDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVRSWTIKKGSSAPVAAGVIHKDFEKGFI
RAETISYDDFIAYKGEAGAKEKGALRIEGKDYIVQDGDVLHFRFNI

Sequences:

>Translated_366_residues
MGLSVGIVGLPNVGKSSTFNALTKTQNAQSANYPFCTIEPNKAIVNVPDRRLDALAQIVKPERILHSVVEFVDIAGLIKG
ASKGEGLGNQFLANIKECEVILQVVRCFEDDNITHVNDKIDPLNDIETIELELILADIAALDKRIDRLQKALKSSKDAKN
LLECALSLKTHLEELKPAKTFPLNTSEAFLELDKELRFLSHKKMIYVANVGEEDLNALNEHAKKVKNHAKEQNSEFVALC
AKLEEEMVSMSGDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVRSWTIKKGSSAPVAAGVIHKDFEKGFI
RAETISYDDFIAYKGEAGAKEKGALRIEGKDYIVQDGDVLHFRFNI
>Mature_365_residues
GLSVGIVGLPNVGKSSTFNALTKTQNAQSANYPFCTIEPNKAIVNVPDRRLDALAQIVKPERILHSVVEFVDIAGLIKGA
SKGEGLGNQFLANIKECEVILQVVRCFEDDNITHVNDKIDPLNDIETIELELILADIAALDKRIDRLQKALKSSKDAKNL
LECALSLKTHLEELKPAKTFPLNTSEAFLELDKELRFLSHKKMIYVANVGEEDLNALNEHAKKVKNHAKEQNSEFVALCA
KLEEEMVSMSGDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVRSWTIKKGSSAPVAAGVIHKDFEKGFIR
AETISYDDFIAYKGEAGAKEKGALRIEGKDYIVQDGDVLHFRFNI

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=42.0054200542005, Blast_Score=278, Evalue=7e-75,
Organism=Homo sapiens, GI58761502, Length=227, Percent_Identity=35.6828193832599, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24308117, Length=113, Percent_Identity=34.5132743362832, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787454, Length=367, Percent_Identity=53.9509536784741, Blast_Score=383, Evalue=1e-108,
Organism=Escherichia coli, GI1789574, Length=167, Percent_Identity=31.7365269461078, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=41.0326086956522, Blast_Score=273, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6319499, Length=373, Percent_Identity=38.8739946380697, Blast_Score=233, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=35.2480417754569, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6321649, Length=165, Percent_Identity=36.969696969697, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=40.2173913043478, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=40.2173913043478, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=40.2173913043478, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=38.0368098159509, Blast_Score=208, Evalue=5e-54,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40575; Mature: 40444

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSVGIVGLPNVGKSSTFNALTKTQNAQSANYPFCTIEPNKAIVNVPDRRLDALAQIVK
CCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHC
PERILHSVVEFVDIAGLIKGASKGEGLGNQFLANIKECEVILQVVRCFEDDNITHVNDKI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
DPLNDIETIELELILADIAALDKRIDRLQKALKSSKDAKNLLECALSLKTHLEELKPAKT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
FPLNTSEAFLELDKELRFLSHKKMIYVANVGEEDLNALNEHAKKVKNHAKEQNSEFVALC
CCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AKLEEEMVSMSGDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVRSWTIKK
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSSAPVAAGVIHKDFEKGFIRAETISYDDFIAYKGEAGAKEKGALRIEGKDYIVQDGDVL
CCCCCHHHHHHHHHHHHCCEEEEEECCCHHEEECCCCCCCCCCEEEECCCEEEEECCCEE
HFRFNI
EEEECC
>Mature Secondary Structure 
GLSVGIVGLPNVGKSSTFNALTKTQNAQSANYPFCTIEPNKAIVNVPDRRLDALAQIVK
CCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHC
PERILHSVVEFVDIAGLIKGASKGEGLGNQFLANIKECEVILQVVRCFEDDNITHVNDKI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
DPLNDIETIELELILADIAALDKRIDRLQKALKSSKDAKNLLECALSLKTHLEELKPAKT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
FPLNTSEAFLELDKELRFLSHKKMIYVANVGEEDLNALNEHAKKVKNHAKEQNSEFVALC
CCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AKLEEEMVSMSGDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVRSWTIKK
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSSAPVAAGVIHKDFEKGFIRAETISYDDFIAYKGEAGAKEKGALRIEGKDYIVQDGDVL
CCCCCHHHHHHHHHHHHCCEEEEEECCCHHEEECCCCCCCCCCEEEECCCEEEEECCCEE
HFRFNI
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]