BacMap

Definition	Helicobacter pylori 26695, complete genome.
Accession	NC_000915
Length	1,667,867

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The map label for this gene is fabG

Identifier: 15645186

GI number: 15645186

Start: 594504

End: 595247

Strand: Reverse

Name: fabG

Synonym: HP0561

Alternate gene names: 15645186

Gene position: 595247-594504 (Counterclockwise)

Preceding gene: 15645187

Following gene: 15645184

Centisome position: 35.69

GC content: 43.55

Gene sequence:

>744_bases
ATGCAATTCACAGGGAAAAATGTTCTCATTACTGGGGCTTCTAAAGGCATTGGGGCTGAAATCGCCAAAACTCTCGCTTC
TATGGGGCTGAAAGTTTGGATCAATTACCGCAGTAATGCTGAAGTGGCTGACGCTTTGAAAAATGAGCTTGAAGAAAAAG
GCTATAAGGCAGCTGTCATTAAATTTGATGCGGCTTCTGAAAGCGATTTTATTGAAGCGATACAAACCATCGTCCAAAGC
GATGGGGGGTTGTCTTACTTGGTGAATAACGCCGGTGTGGTGCGCGATAAATTAGCGATCAAAATGAAAACAGAAGACTT
TCACCATGTCATAGACAATAACCTCACTTCAGCCTTTATAGGTTGCCGAGAGGCTTTAAAGGTGATGAGCAAGAGTCGTT
TTGGGAGCGTGGTCAATGTCGCTTCTATCATTGGTGAAAGAGGCAATATGGGGCAGACAAACTACTCAGCGAGTAAGGGG
GGAATGATTGCAATGAGCAAGTCCTTTGCTTATGAGGGAGCTTTAAGGAATATTCGTTTCAACTCTGTAACGCCCGGTTT
TATAGAAACCGACATGAACGCCAATTTGAAAGACGAACTCAAAGCGGATTATGTTAAAAACATTCCTTTAAACAGGCTAG
GGTCTGCTAAGGAAGTGGCAGAAGCGGTAGCGTTTCTTTTGAGTGATCACTCTAGTTACATCACTGGAGAGACTCTCAAA
GTCAATGGCGGGCTTTATATGTAG

Upstream 100 bases:

>100_bases
CTAAAAAGAAGGTTTTGAAGCGTCTTTATATGTTAAGGCGTTATGAGTCAAGACTATAATAGACTTTAAGAAAAATTTAA
AAATTAAGGATTATTGAATA

Downstream 100 bases:

>100_bases
TCCTAAACAAAGGGTTCTTTTAGCGATAAAAGTTTGTAAGTAGCAAAAATCATGCTAACATTATGAGGTTATTCTAAAAC
AAAGAGGTTATTATCAAATG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASESDFIEAIQTIVQS
DGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKG
GMIAMSKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLK
VNGGLYM

Sequences:

>Translated_247_residues
MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASESDFIEAIQTIVQS
DGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKG
GMIAMSKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLK
VNGGLYM
>Mature_247_residues
MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASESDFIEAIQTIVQS
DGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKG
GMIAMSKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLK
VNGGLYM

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=41.1764705882353, Blast_Score=168, Evalue=3e-42,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=34.136546184739, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=33.0578512396694, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI4504505, Length=258, Percent_Identity=28.6821705426357, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=31.8548387096774, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=29.0836653386454, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=27.2, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI109715829, Length=228, Percent_Identity=28.9473684210526, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI59889578, Length=202, Percent_Identity=29.7029702970297, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=28.5140562248996, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=26.8774703557312, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI66933014, Length=171, Percent_Identity=26.9005847953216, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI33667109, Length=241, Percent_Identity=28.2157676348548, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503301, Length=250, Percent_Identity=26.8, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=31.0734463276836, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=25.3886010362694, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=45.3441295546559, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=38.4297520661157, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=32.5396825396825, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=31.5789473684211, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=29.1666666666667, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=29.0983606557377, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=30.6122448979592, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=28.740157480315, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=28.6885245901639, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=31.0204081632653, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=27.6, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=25.1937984496124, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787526, Length=240, Percent_Identity=25.8333333333333, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=38.3673469387755, Blast_Score=157, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=38.0769230769231, Blast_Score=153, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=35.7142857142857, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17568967, Length=222, Percent_Identity=33.7837837837838, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=31.9391634980989, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=32.1138211382114, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=30.952380952381, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=31.3492063492063, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=32.7935222672065, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=32.1138211382114, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.8973384030418, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=29.277566539924, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=30.1526717557252, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=29.9595141700405, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=29.1187739463602, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=28.3018867924528, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=30.9433962264151, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.4615384615385, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=31.9371727748691, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=28.5171102661597, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.8461538461538, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=27.9693486590038, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.0076335877863, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=31.3131313131313, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=277, Percent_Identity=27.7978339350181, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=30, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=31.9587628865979, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=26.8421052631579, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=26.7175572519084, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=28.1124497991968, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=125, Percent_Identity=31.2, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=257, Percent_Identity=31.9066147859922, Blast_Score=108, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=28.4584980237154, Blast_Score=82, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=244, Percent_Identity=27.8688524590164, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=35.2226720647773, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=35.2, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=34.1176470588235, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.8, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=33.1967213114754, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.6, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=31.7269076305221, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI18859837, Length=246, Percent_Identity=29.6747967479675, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=30.078125, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=31.3492063492063, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24641232, Length=238, Percent_Identity=26.890756302521, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=29.2929292929293, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24665243, Length=206, Percent_Identity=28.6407766990291, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221331218, Length=206, Percent_Identity=28.6407766990291, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24648944, Length=233, Percent_Identity=27.0386266094421, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641388, Length=237, Percent_Identity=27.0042194092827, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24665247, Length=207, Percent_Identity=28.0193236714976, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221331216, Length=207, Percent_Identity=28.0193236714976, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=30.0518134715026, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076933, Length=194, Percent_Identity=30.4123711340206, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=26.0683760683761, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571387, Length=243, Percent_Identity=27.5720164609054, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=30.9278350515464, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=30.9278350515464, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26669; Mature: 26669

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVI
CCCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEE
KFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFI
EECCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEECHHHHHHHHCCHHHHHH
GCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRF
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCEE
NSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLK
CCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCEECCCEEE
VNGGLYM
ECCCCCC
>Mature Secondary Structure
MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVI
CCCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEE
KFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFI
EECCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEECHHHHHHHHCCHHHHHH
GCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRF
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCEE
NSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLK
CCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCEECCCEEE
VNGGLYM
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA