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Identifier: 15645024

GI number: 15645024

Start: 405404

End: 407254

Strand: Reverse

Name: Not Available

Synonym: HP0396

Alternate gene names: 15645024

Gene position: 407254-405404 (Counterclockwise)

Preceding gene: 15645025

Following gene: 15645023

Centisome position: 24.42

GC content: 40.41

Gene sequence:

>1851_bases
ATGCGAGATTTTTTAAAACTTTTAAAAAAGCATGATGAATTAAAAATCATTGACACCCCCCTTGAAGTGGATTTAGAAAT
CGCTCATCTAGCCTATATAGAAGCGAAAAAACCTAATGGGGGCAAAGCCCTTTTATTCACGCAACCCATAAGAAAAGAGC
ATGACCAGATCAAAACCTTTGGCATGCCTGTTTTAATGAACGCTTTTGGCTCTTTCAAACGCTTGGATCTTTTGTTAAAA
ACCCCCATAGAAAGCCTGCAACAACGCATGCAAGCGTTCTTACACTTTAACGCTCCTAAAAATTTCACTGAGGGTTTGAA
AGTCTTAAAAGATTTATGGGATTTAAGACACATTTTCCCTAAAAAAACCACTCGCCCTAAAGATCTCATCATCAAGCAAG
ATAAAGAAGTCAATTTATTGGATCTACCCGTTTTAAAAACTTGGGAAAAAGATGGCGGGGCTTTTATCACTATGGGGCAA
GTCTATACCCAAAGCTTGGATCATCAAAAAAAGAATTTAGGCATGTATCGTTTGCAAGTTTATGATAAAAACCATTTAGG
CTTGCACTGGCAAATCCATAAAGACTCCCAACTCTTTTTCCACGAATACGCTAAGGCTAAAGTCAAAATGCCTGTCAGTA
TCGCTATTGGTGGGGATTTGCTCTACACATGGTGCGCGACAGCCCCCCTACCTTATGGGATTTATGAACTCATGCTCTAT
GGGTTTATGAGAGGAAAAAAAGCGCGCGTAATGCCATGCCTAAGCAACTCTTTAAGCGTGCCAAGCGACTGCGATATTGT
GATAGAAGGGTTTGTAGATTGCGAAAAGCTAGAGCTTGAAGGGCCTTTTGGGGATCACACTGGCTATTACACCCCTATTG
AGCCTTATCCTGTTTTAGAAGTCAAAACCATTAGCTACAAAAAAGATTCCATTTACTTAGCCACTGTGGTGGGTAAGCCC
CCTTTAGAAGACAAATACATGGGGTATTTGACTGAACGCTTGTTCTTGCCCTTGCTTCAAATGAACGCCCCCAATCTCAT
AGAATATTACATGCCAGAAAATGGGGTGTTTCATAATTTGATTTTAGCCAAAATACACACGCGCTATAACGCTCATGCCA
AGCAAGTCATGCATGCTTTTTGGGGTGTGGGGCAGATGAGTTTTGTCAAACATGCGATTTTTGTCAATGAAGACGCTCCT
AATCTAAGAGACACCAACGCTATCATTGAGTATATACTAGAGAATTTTTCTAAAGAAAACGCGCTCATCTCTCAAGGCGT
ATGCGACGCCTTAGATCATGCAAGCCCTGAATACGCTATGGGGGGGAAACTCGGTATTGATGCGACCTCTAAAAGCAATA
CCCCCTACCCCACGCTTTTAAACGATAGTGCCTTATTAGCGCTTTTACAAGATAAAATGCAAAATATCGTTCTTTTGAAG
CAATATTACCCGCACACCCGTAACCCCATTTGCGTCATTAGCGTGGAAAAGAAAGACAAAAGCGTCATTGAATTGGCTAA
AAACTTGCTCGGTTTTGAAGAACATTTACGCATTGTCATCTTTGTAGAGCATGCCAGCAACGATTTGAACAACCCTTACA
TGCTGTTATGGCGCATCGTTAATAATATTGACGCCAGGCGTGATATTCTCACCTCTAAACATTGCTTTTTTATAGACGCT
ACCAATAAGGGCGTTATGGATAAACATTTTAGAGAATGGCCCACCGAAACCAATTGCTCCATGGAAGTCATAGAAAATTT
GAAAAAGAAAGGGCTTTTAAAAGATTTTGAAACTTTAAATCAAAAATTCCACCTCACGCATTCTTTCAGCACGCACAAAG
AAGATCTATAA

Upstream 100 bases:

>100_bases
CATTATTGTAGATGAAGAAGTTTCTTTGGAAGTTTTAGAAGAGCTTAAAAACATTCCTGCGTGCTTAAGCGTTCATTATG
TGGTTATTTAAGGTAGTTGG

Downstream 100 bases:

>100_bases
AGAATAGCCATAAAGAAGAATTATGTTAGATTATCGCCAAAAAATTGATGCTCTCATCACCAAAATAGAAAAGGCTCGCA
CCGCCTATTCAAGGCACCAC

Product: hypothetical protein

Products: 2-octaprenylphenol; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MRDFLKLLKKHDELKIIDTPLEVDLEIAHLAYIEAKKPNGGKALLFTQPIRKEHDQIKTFGMPVLMNAFGSFKRLDLLLK
TPIESLQQRMQAFLHFNAPKNFTEGLKVLKDLWDLRHIFPKKTTRPKDLIIKQDKEVNLLDLPVLKTWEKDGGAFITMGQ
VYTQSLDHQKKNLGMYRLQVYDKNHLGLHWQIHKDSQLFFHEYAKAKVKMPVSIAIGGDLLYTWCATAPLPYGIYELMLY
GFMRGKKARVMPCLSNSLSVPSDCDIVIEGFVDCEKLELEGPFGDHTGYYTPIEPYPVLEVKTISYKKDSIYLATVVGKP
PLEDKYMGYLTERLFLPLLQMNAPNLIEYYMPENGVFHNLILAKIHTRYNAHAKQVMHAFWGVGQMSFVKHAIFVNEDAP
NLRDTNAIIEYILENFSKENALISQGVCDALDHASPEYAMGGKLGIDATSKSNTPYPTLLNDSALLALLQDKMQNIVLLK
QYYPHTRNPICVISVEKKDKSVIELAKNLLGFEEHLRIVIFVEHASNDLNNPYMLLWRIVNNIDARRDILTSKHCFFIDA
TNKGVMDKHFREWPTETNCSMEVIENLKKKGLLKDFETLNQKFHLTHSFSTHKEDL

Sequences:

>Translated_616_residues
MRDFLKLLKKHDELKIIDTPLEVDLEIAHLAYIEAKKPNGGKALLFTQPIRKEHDQIKTFGMPVLMNAFGSFKRLDLLLK
TPIESLQQRMQAFLHFNAPKNFTEGLKVLKDLWDLRHIFPKKTTRPKDLIIKQDKEVNLLDLPVLKTWEKDGGAFITMGQ
VYTQSLDHQKKNLGMYRLQVYDKNHLGLHWQIHKDSQLFFHEYAKAKVKMPVSIAIGGDLLYTWCATAPLPYGIYELMLY
GFMRGKKARVMPCLSNSLSVPSDCDIVIEGFVDCEKLELEGPFGDHTGYYTPIEPYPVLEVKTISYKKDSIYLATVVGKP
PLEDKYMGYLTERLFLPLLQMNAPNLIEYYMPENGVFHNLILAKIHTRYNAHAKQVMHAFWGVGQMSFVKHAIFVNEDAP
NLRDTNAIIEYILENFSKENALISQGVCDALDHASPEYAMGGKLGIDATSKSNTPYPTLLNDSALLALLQDKMQNIVLLK
QYYPHTRNPICVISVEKKDKSVIELAKNLLGFEEHLRIVIFVEHASNDLNNPYMLLWRIVNNIDARRDILTSKHCFFIDA
TNKGVMDKHFREWPTETNCSMEVIENLKKKGLLKDFETLNQKFHLTHSFSTHKEDL
>Mature_616_residues
MRDFLKLLKKHDELKIIDTPLEVDLEIAHLAYIEAKKPNGGKALLFTQPIRKEHDQIKTFGMPVLMNAFGSFKRLDLLLK
TPIESLQQRMQAFLHFNAPKNFTEGLKVLKDLWDLRHIFPKKTTRPKDLIIKQDKEVNLLDLPVLKTWEKDGGAFITMGQ
VYTQSLDHQKKNLGMYRLQVYDKNHLGLHWQIHKDSQLFFHEYAKAKVKMPVSIAIGGDLLYTWCATAPLPYGIYELMLY
GFMRGKKARVMPCLSNSLSVPSDCDIVIEGFVDCEKLELEGPFGDHTGYYTPIEPYPVLEVKTISYKKDSIYLATVVGKP
PLEDKYMGYLTERLFLPLLQMNAPNLIEYYMPENGVFHNLILAKIHTRYNAHAKQVMHAFWGVGQMSFVKHAIFVNEDAP
NLRDTNAIIEYILENFSKENALISQGVCDALDHASPEYAMGGKLGIDATSKSNTPYPTLLNDSALLALLQDKMQNIVLLK
QYYPHTRNPICVISVEKKDKSVIELAKNLLGFEEHLRIVIFVEHASNDLNNPYMLLWRIVNNIDARRDILTSKHCFFIDA
TNKGVMDKHFREWPTETNCSMEVIENLKKKGLLKDFETLNQKFHLTHSFSTHKEDL

Specific function: Unknown

COG id: COG0043

COG function: function code H; 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiD family [H]

Homologues:

Organism=Escherichia coli, GI1790277, Length=468, Percent_Identity=33.974358974359, Blast_Score=266, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6320748, Length=324, Percent_Identity=25, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002830
- InterPro:   IPR022390
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01977 UbiD [H]

EC number: NA

Molecular weight: Translated: 70845; Mature: 70845

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDFLKLLKKHDELKIIDTPLEVDLEIAHLAYIEAKKPNGGKALLFTQPIRKEHDQIKTF
CHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEEEECCCCCEEEEEECCHHHHHHHHHHC
GMPVLMNAFGSFKRLDLLLKTPIESLQQRMQAFLHFNAPKNFTEGLKVLKDLWDLRHIFP
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCC
KKTTRPKDLIIKQDKEVNLLDLPVLKTWEKDGGAFITMGQVYTQSLDHQKKNLGMYRLQV
CCCCCCHHEEEECCCCCCEEECCCHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCEEEEEE
YDKNHLGLHWQIHKDSQLFFHEYAKAKVKMPVSIAIGGDLLYTWCATAPLPYGIYELMLY
ECCCCCEEEEEEECCCHHHHHHHHHHEEECCEEEEECCHHHHHHHHCCCCCHHHHHHHHH
GFMRGKKARVMPCLSNSLSVPSDCDIVIEGFVDCEKLELEGPFGDHTGYYTPIEPYPVLE
HHHCCCCCEEEHHHCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEEE
VKTISYKKDSIYLATVVGKPPLEDKYMGYLTERLFLPLLQMNAPNLIEYYMPENGVFHNL
EEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
ILAKIHTRYNAHAKQVMHAFWGVGQMSFVKHAIFVNEDAPNLRDTNAIIEYILENFSKEN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
ALISQGVCDALDHASPEYAMGGKLGIDATSKSNTPYPTLLNDSALLALLQDKMQNIVLLK
HHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHHEEEEH
QYYPHTRNPICVISVEKKDKSVIELAKNLLGFEEHLRIVIFVEHASNDLNNPYMLLWRIV
HHCCCCCCCEEEEEECCCCHHHHHHHHHHHCHHHCCEEEEEEEECCCCCCCHHHHHHHHH
NNIDARRDILTSKHCFFIDATNKGVMDKHFREWPTETNCSMEVIENLKKKGLLKDFETLN
HCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHC
QKFHLTHSFSTHKEDL
CEEEEEECCCCCCCCC
>Mature Secondary Structure
MRDFLKLLKKHDELKIIDTPLEVDLEIAHLAYIEAKKPNGGKALLFTQPIRKEHDQIKTF
CHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEEEECCCCCEEEEEECCHHHHHHHHHHC
GMPVLMNAFGSFKRLDLLLKTPIESLQQRMQAFLHFNAPKNFTEGLKVLKDLWDLRHIFP
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCC
KKTTRPKDLIIKQDKEVNLLDLPVLKTWEKDGGAFITMGQVYTQSLDHQKKNLGMYRLQV
CCCCCCHHEEEECCCCCCEEECCCHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCEEEEEE
YDKNHLGLHWQIHKDSQLFFHEYAKAKVKMPVSIAIGGDLLYTWCATAPLPYGIYELMLY
ECCCCCEEEEEEECCCHHHHHHHHHHEEECCEEEEECCHHHHHHHHCCCCCHHHHHHHHH
GFMRGKKARVMPCLSNSLSVPSDCDIVIEGFVDCEKLELEGPFGDHTGYYTPIEPYPVLE
HHHCCCCCEEEHHHCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEEE
VKTISYKKDSIYLATVVGKPPLEDKYMGYLTERLFLPLLQMNAPNLIEYYMPENGVFHNL
EEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
ILAKIHTRYNAHAKQVMHAFWGVGQMSFVKHAIFVNEDAPNLRDTNAIIEYILENFSKEN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
ALISQGVCDALDHASPEYAMGGKLGIDATSKSNTPYPTLLNDSALLALLQDKMQNIVLLK
HHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHHEEEEH
QYYPHTRNPICVISVEKKDKSVIELAKNLLGFEEHLRIVIFVEHASNDLNNPYMLLWRIV
HHCCCCCCCEEEEEECCCCHHHHHHHHHHHCHHHCCEEEEEEEECCCCCCCHHHHHHHHH
NNIDARRDILTSKHCFFIDATNKGVMDKHFREWPTETNCSMEVIENLKKKGLLKDFETLN
HCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHC
QKFHLTHSFSTHKEDL
CEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-octaprenyl-4-hydroxybenzoate [C]

Specific reaction: 3-octaprenyl-4-hydroxybenzoate = 2-octaprenylphenol + CO2 [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]