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Identifier: 15644872

GI number: 15644872

Start: 252912

End: 254057

Strand: Reverse

Name: Not Available

Synonym: HP0244

Alternate gene names: 15644872

Gene position: 254057-252912 (Counterclockwise)

Preceding gene: 15644873

Following gene: 15644871

Centisome position: 15.23

GC content: 36.21

Gene sequence:

>1146_bases
ATGAAAAAATCCAAGCACTTAAAACGCCCTTATTTGAAGCGTTCCCATTTGAAACACTCTGATAAGGCTTCTTCTTTCAA
GGGGTTGTTAAAAAAAGAGGATAATGTGATTTCATTAGAAAATTTTAAACCCAAAGAGAGCGAAGATTTATTAGAAAATT
TTTCCAACAAAAAAGACATGCAAGAATTGCTAGGGCTTTTAAACCAATTTATTTTGCAAAGCTACAAGGTAGAAAAGGAA
TTTAAAGATTATAAAGCCCTTTATGAATGGGTCATAGAGATTTTACCTCAAGCCATTTGGGTGGTGAATGAAAACGGGAG
CTTTTTTTATAAAAATTCTTTAGCCAATCAAAGCCATGAGGTGTTCAATAAGGCTAAATTAGAAAATTTTAACACTGAAA
TTGAACATGAAAATAAAAGCTATTTAGTCCAGCAAAACAGCATTCAAGGCAAGCAAATCATCACCGCAACCGATATTAGC
GCTCAAAAACGCCAAGAGCGGCTCGCTTCTATGGGGAAAATCTCAGCGCATTTAGCCCATGAGATCAGAAACCCTGTAGG
TTCTATCTCTCTTTTAGCTTCAGTGTTATTAAAGCATGCGAACGAAAAGACTAAGCCCATTGTTGTAGAATTGCAAAAAG
CTTTATGGCGCGTGGAAAGAATCATTAAAGCCACCTTGCTTTTTTCTAAAGGCATTCAAGCCAACCGCACCAAGCAAAGT
TTGAAAACGCTAGAGAGCGATCTCAAAGAAGCCCTAAATTGCTACACTTACTCTAAAGACATTGATTTTCTTTTTAATTT
TAGCGACGAAGAAGGGTTTTTTGACTTTGATTTGATGGGGATTGTGTTGCAAAATTTCTTGTATAACGCTATTGATGCGA
TTGAAGCCTTAGAAGAGAGCGAACAGGGTCAAGTGAAGATTGAAGCGTTCATTCAAAATGAATTTATTGTCTTCACTATT
ATTGATAATGGCAAGGAAGTGGAAAACAAAAGCGCTTTATTTGAGCCTTTTGAAACCACTAAATTAAAGGGTAACGGCCT
AGGGTTAGCCTTGTCTTTACAAGTGGTTAAAGCCCATGAAGGGAGCATTGCGCTATTAGAAAATCAAGAAAAAACCTTTG
AAATTAAGATTCTTAACGCTTCTTAA

Upstream 100 bases:

>100_bases
CGTCCATGTATAAGGACACGCTTTCTAAAGAATTGAGCGGGAATTTTGGCTATAGCGAAATGCTGTTTAATTTCTTAAAA
GAGCAAGAAAAACAAAAACC

Downstream 100 bases:

>100_bases
TTTGGATAACTATCCCCCTTAAAAATGAGTTTTACTATAAAACAAAATTTTAAAAAGATTAAATAATATTAAATTGAATG
GGGTTTATCAATATTTGACA

Product: signal-transducing protein, histidine kinase (atoS)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKKSKHLKRPYLKRSHLKHSDKASSFKGLLKKEDNVISLENFKPKESEDLLENFSNKKDMQELLGLLNQFILQSYKVEKE
FKDYKALYEWVIEILPQAIWVVNENGSFFYKNSLANQSHEVFNKAKLENFNTEIEHENKSYLVQQNSIQGKQIITATDIS
AQKRQERLASMGKISAHLAHEIRNPVGSISLLASVLLKHANEKTKPIVVELQKALWRVERIIKATLLFSKGIQANRTKQS
LKTLESDLKEALNCYTYSKDIDFLFNFSDEEGFFDFDLMGIVLQNFLYNAIDAIEALEESEQGQVKIEAFIQNEFIVFTI
IDNGKEVENKSALFEPFETTKLKGNGLGLALSLQVVKAHEGSIALLENQEKTFEIKILNAS

Sequences:

>Translated_381_residues
MKKSKHLKRPYLKRSHLKHSDKASSFKGLLKKEDNVISLENFKPKESEDLLENFSNKKDMQELLGLLNQFILQSYKVEKE
FKDYKALYEWVIEILPQAIWVVNENGSFFYKNSLANQSHEVFNKAKLENFNTEIEHENKSYLVQQNSIQGKQIITATDIS
AQKRQERLASMGKISAHLAHEIRNPVGSISLLASVLLKHANEKTKPIVVELQKALWRVERIIKATLLFSKGIQANRTKQS
LKTLESDLKEALNCYTYSKDIDFLFNFSDEEGFFDFDLMGIVLQNFLYNAIDAIEALEESEQGQVKIEAFIQNEFIVFTI
IDNGKEVENKSALFEPFETTKLKGNGLGLALSLQVVKAHEGSIALLENQEKTFEIKILNAS
>Mature_381_residues
MKKSKHLKRPYLKRSHLKHSDKASSFKGLLKKEDNVISLENFKPKESEDLLENFSNKKDMQELLGLLNQFILQSYKVEKE
FKDYKALYEWVIEILPQAIWVVNENGSFFYKNSLANQSHEVFNKAKLENFNTEIEHENKSYLVQQNSIQGKQIITATDIS
AQKRQERLASMGKISAHLAHEIRNPVGSISLLASVLLKHANEKTKPIVVELQKALWRVERIIKATLLFSKGIQANRTKQS
LKTLESDLKEALNCYTYSKDIDFLFNFSDEEGFFDFDLMGIVLQNFLYNAIDAIEALEESEQGQVKIEAFIQNEFIVFTI
IDNGKEVENKSALFEPFETTKLKGNGLGLALSLQVVKAHEGSIALLENQEKTFEIKILNAS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=29.535864978903, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=29.8642533936652, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43656; Mature: 43656

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSKHLKRPYLKRSHLKHSDKASSFKGLLKKEDNVISLENFKPKESEDLLENFSNKKDM
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCHHHH
QELLGLLNQFILQSYKVEKEFKDYKALYEWVIEILPQAIWVVNENGSFFYKNSLANQSHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCHHHH
VFNKAKLENFNTEIEHENKSYLVQQNSIQGKQIITATDISAQKRQERLASMGKISAHLAH
HHHHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
EIRNPVGSISLLASVLLKHANEKTKPIVVELQKALWRVERIIKATLLFSKGIQANRTKQS
HHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LKTLESDLKEALNCYTYSKDIDFLFNFSDEEGFFDFDLMGIVLQNFLYNAIDAIEALEES
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EQGQVKIEAFIQNEFIVFTIIDNGKEVENKSALFEPFETTKLKGNGLGLALSLQVVKAHE
CCCCEEEEEEECCCEEEEEEECCCCCCCCCHHHCCCCHHCEECCCCCEEEEEEEEEEECC
GSIALLENQEKTFEIKILNAS
CCEEEEECCCCEEEEEEEECC
>Mature Secondary Structure
MKKSKHLKRPYLKRSHLKHSDKASSFKGLLKKEDNVISLENFKPKESEDLLENFSNKKDM
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCHHHH
QELLGLLNQFILQSYKVEKEFKDYKALYEWVIEILPQAIWVVNENGSFFYKNSLANQSHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCHHHH
VFNKAKLENFNTEIEHENKSYLVQQNSIQGKQIITATDISAQKRQERLASMGKISAHLAH
HHHHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
EIRNPVGSISLLASVLLKHANEKTKPIVVELQKALWRVERIIKATLLFSKGIQANRTKQS
HHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LKTLESDLKEALNCYTYSKDIDFLFNFSDEEGFFDFDLMGIVLQNFLYNAIDAIEALEES
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EQGQVKIEAFIQNEFIVFTIIDNGKEVENKSALFEPFETTKLKGNGLGLALSLQVVKAHE
CCCCEEEEEEECCCEEEEEEECCCCCCCCCHHHCCCCHHCEECCCCCEEEEEEEEEEECC
GSIALLENQEKTFEIKILNAS
CCEEEEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]