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Identifier: 15644863

GI number: 15644863

Start: 245098

End: 246165

Strand: Reverse

Name: Not Available

Synonym: HP0235

Alternate gene names: 15644863

Gene position: 246165-245098 (Counterclockwise)

Preceding gene: 15644864

Following gene: 15644858

Centisome position: 14.76

GC content: 41.1

Gene sequence:

>1068_bases
ATGGGTGTCAAATTTTTAAAAATATTAGTTTGTGGGTTATTTTTTTGGAGCTTGAACGCCCATTTATGGGGAAAACAAGA
CAATAGTTTTTTGGGGGTTGCTGAAAAAGCCTATAAAAGCGGGAATTATTCTAAAGCCACATCTTATTTTAAAAAAGCAT
GCAACGATGGGGTGAGTGAAGGTTGCACGCAATTAGGAATCATTTATGAAAACGGGCAAGGCACTAGAATAGATTATAAA
AAAGCCCTAGAATATTATAAAACCGCATGCCAGGCTGATGATAGGGAAGGGTGTTTTGGTTTAGGGGGGCTTTATGATGA
GGGGTTAGGCACGACTCAAAATTATCAAGAAGCCATTGACGCTTATGCTAAGGCGTGCGTTTTAAAACACCCTGAGAGTT
GCTACAATTTAGGCATTATTTATGACCGAAAAATCAAAGGCAATGCCGATCAAGCGGTTACCTACTACCAAAAAAGCTGT
AATTTTGATATGGCTAAGGGGTGTTATGTTTTGGGCGTGGCTTATGAAAAAGGCTTTTTAGAAGTCAAACAAAGCAACCA
TAAAGCCGTCATCTATTATTTGAAAGCATGCCGATTGGATGATGGGCAGGCTTGTCGCGCGTTAGGGAGTTTGTTTGAAA
ATGGCGATGCAGGGCTTGATGAAGATTTTGAAGTGGCGTTTGATTACTTGCAAAAAGCTTGCGGGTTAAACAATTCTGGT
GGTTGCGCGAGTTTAGGCTCTATGTATATGTTAGGCAGGTATGTCAAAAAAGATCCCCAAAAGGCTTTTAATTTTTTCAA
ACAAGCATGCGATATGGGGAGTGCGGTGAGTTGCTCTAGGATGGGCTTTATGTATTCCCAAGGGGACGCTGTTCCAAAAG
ACTTGAGGAAAGCCCTTGATAATTATGAAAGGGGTTGCGATATGGGCGATGAAGTGGGTTGCTTCGCTCTAGCGGGCATG
TATTACAACATGAAAGACAAAGAAAACGCCATAATGATTTATGACAAGGGCTGTAAGCTAGGCATGAAACAAGCATGCGA
AAACCTCACTAAACTTAGGGGGTATTGA

Upstream 100 bases:

>100_bases
AGCCTTAATCAAAGCGCTTGATTTATGCTAAAATGGAGCGTTGCATTTTTGTTTTGATTAAAGAAGGGTTCTAAAAATCA
GAATTTAAAAGAAGGTAAAA

Downstream 100 bases:

>100_bases
AAATTTAATCAACCCCCTAAATTATCATTGCGTTTGACTCAAAACTTTTCAAAGATTTGGCTCTGTTTTGAAAACCCAAG
CAGAAAGCCCCCCCTATTAA

Product: hypothetical protein

Products: NA

Alternate protein names: Cysteine-rich protein E [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MGVKFLKILVCGLFFWSLNAHLWGKQDNSFLGVAEKAYKSGNYSKATSYFKKACNDGVSEGCTQLGIIYENGQGTRIDYK
KALEYYKTACQADDREGCFGLGGLYDEGLGTTQNYQEAIDAYAKACVLKHPESCYNLGIIYDRKIKGNADQAVTYYQKSC
NFDMAKGCYVLGVAYEKGFLEVKQSNHKAVIYYLKACRLDDGQACRALGSLFENGDAGLDEDFEVAFDYLQKACGLNNSG
GCASLGSMYMLGRYVKKDPQKAFNFFKQACDMGSAVSCSRMGFMYSQGDAVPKDLRKALDNYERGCDMGDEVGCFALAGM
YYNMKDKENAIMIYDKGCKLGMKQACENLTKLRGY

Sequences:

>Translated_355_residues
MGVKFLKILVCGLFFWSLNAHLWGKQDNSFLGVAEKAYKSGNYSKATSYFKKACNDGVSEGCTQLGIIYENGQGTRIDYK
KALEYYKTACQADDREGCFGLGGLYDEGLGTTQNYQEAIDAYAKACVLKHPESCYNLGIIYDRKIKGNADQAVTYYQKSC
NFDMAKGCYVLGVAYEKGFLEVKQSNHKAVIYYLKACRLDDGQACRALGSLFENGDAGLDEDFEVAFDYLQKACGLNNSG
GCASLGSMYMLGRYVKKDPQKAFNFFKQACDMGSAVSCSRMGFMYSQGDAVPKDLRKALDNYERGCDMGDEVGCFALAGM
YYNMKDKENAIMIYDKGCKLGMKQACENLTKLRGY
>Mature_354_residues
GVKFLKILVCGLFFWSLNAHLWGKQDNSFLGVAEKAYKSGNYSKATSYFKKACNDGVSEGCTQLGIIYENGQGTRIDYKK
ALEYYKTACQADDREGCFGLGGLYDEGLGTTQNYQEAIDAYAKACVLKHPESCYNLGIIYDRKIKGNADQAVTYYQKSCN
FDMAKGCYVLGVAYEKGFLEVKQSNHKAVIYYLKACRLDDGQACRALGSLFENGDAGLDEDFEVAFDYLQKACGLNNSGG
CASLGSMYMLGRYVKKDPQKAFNFFKQACDMGSAVSCSRMGFMYSQGDAVPKDLRKALDNYERGCDMGDEVGCFALAGMY
YNMKDKENAIMIYDKGCKLGMKQACENLTKLRGY

Specific function: May hydrolyze 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives [H]

COG id: COG0790

COG function: function code R; FOG: TPR repeat, SEL1 subfamily

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI19923669, Length=322, Percent_Identity=27.639751552795, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI151301150, Length=323, Percent_Identity=23.5294117647059, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI87081769, Length=260, Percent_Identity=25.7692307692308, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17537799, Length=231, Percent_Identity=29.004329004329, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17563256, Length=330, Percent_Identity=24.5454545454545, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319410, Length=274, Percent_Identity=24.4525547445255, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355295, Length=284, Percent_Identity=27.112676056338, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI116007256, Length=221, Percent_Identity=28.5067873303167, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 39399; Mature: 39268

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVKFLKILVCGLFFWSLNAHLWGKQDNSFLGVAEKAYKSGNYSKATSYFKKACNDGVSE
CCHHHHHHHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHCCCHHH
GCTQLGIIYENGQGTRIDYKKALEYYKTACQADDREGCFGLGGLYDEGLGTTQNYQEAID
HHHEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCHHCCCCCCHHHHHHHH
AYAKACVLKHPESCYNLGIIYDRKIKGNADQAVTYYQKSCNFDMAKGCYVLGVAYEKGFL
HHHHHHHHCCCHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEHHCCCC
EVKQSNHKAVIYYLKACRLDDGQACRALGSLFENGDAGLDEDFEVAFDYLQKACGLNNSG
EECCCCCCEEEEEEEHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCC
GCASLGSMYMLGRYVKKDPQKAFNFFKQACDMGSAVSCSRMGFMYSQGDAVPKDLRKALD
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHCCEECCCCCCHHHHHHHHH
NYERGCDMGDEVGCFALAGMYYNMKDKENAIMIYDKGCKLGMKQACENLTKLRGY
HHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GVKFLKILVCGLFFWSLNAHLWGKQDNSFLGVAEKAYKSGNYSKATSYFKKACNDGVSE
CHHHHHHHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHCCCHHH
GCTQLGIIYENGQGTRIDYKKALEYYKTACQADDREGCFGLGGLYDEGLGTTQNYQEAID
HHHEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCHHCCCCCCHHHHHHHH
AYAKACVLKHPESCYNLGIIYDRKIKGNADQAVTYYQKSCNFDMAKGCYVLGVAYEKGFL
HHHHHHHHCCCHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEHHCCCC
EVKQSNHKAVIYYLKACRLDDGQACRALGSLFENGDAGLDEDFEVAFDYLQKACGLNNSG
EECCCCCCEEEEEEEHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCC
GCASLGSMYMLGRYVKKDPQKAFNFFKQACDMGSAVSCSRMGFMYSQGDAVPKDLRKALD
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHCCEECCCCCCHHHHHHHHH
NYERGCDMGDEVGCFALAGMYYNMKDKENAIMIYDKGCKLGMKQACENLTKLRGY
HHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]