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Identifier: 15644733

GI number: 15644733

Start: 109025

End: 110722

Strand: Reverse

Name: Not Available

Synonym: HP0103

Alternate gene names: 15644733

Gene position: 110722-109025 (Counterclockwise)

Preceding gene: 15644734

Following gene: 15644732

Centisome position: 6.64

GC content: 41.81

Gene sequence:

>1698_bases
ATGATGTTTTCTTCAATGTTTGCTTCGTTGGGGACTCGTATCATGCTGGTCGTGTTAGCCGCTCTTTTAGGTTTAGGGGG
GCTTTTTATTGGTTTTGTAAAGGTTATGCAAAAAGATGTGTTAGCGCAACTCATGGAGCATTTAGAAACCGGGCAATACA
AAAAGCGTGAAAAAACGCTCGCTTACATGACAAAAATTATTGAACAGGGCATTCATGAGTATTACAAAAATTTTGACAAT
GCTACTGCAAGAAAAATGGCGTTAGATTATTTCAAACGCATCAACGACGATAAGGGCATGATTTATATGGTGGTGGTGGA
TAAAAACGGGGTGGTATTGTTTGATCCGGTCAATCCTAAAACCGTAGGCCAATCAGGGCTTGACGCTCAGAGCGTTGATG
GGGTGTATTATGTTAGGGGGTATTTGGAGGCGGCCAAAAAAGGGGGAGGCTACACTTATTATAAAATGCCTAAATACGAT
GGAGGCGTACCGGAGAAAAAATTCGCCTACTCGCATTATGATGAAGTTTCTCAAATGGTGATCGCAACGACTTCCTATTA
CACTGACATTAACACAGAAAATAAAGCGATCAAAGAAGGCGTGAATAAGGTTTTTGATGAAAACACCACGAAATTATTCC
TTTGGATACTGACAGCGACGATAGCGCTAGTGGTTTTGACGCTCATATACGCTAAATTAAGGATCGTGAAACGCATTGAT
GAACTGGTCCTTAAAATCAACGCTTTTAGCCGTGGGGATAAGGATTTGAGAGCCAAAATTGATGTGGGTGATCGCAACGA
TGAAATCTCGCAAGTGGGCCGTGGGATCAATTTGTTTGTGGAAAACGCCCGCTTGATTATGGAAGAGATTAAAGGGATTT
CCACCCTCAATAAAACTTCAATGGATAAATTAGTCCAAATCACGCAAGAAACCCAAAAGAGCATGAAAGATTCCTCAACC
ACCCTAAATTCCGTGAAAAATAAAGCCACTGATATAGCGAGCATGATGAATGCTTCCATAGAGCAATCTCAAGGGTTAAG
GAAGCGTTTGATTGAAACGCAAGGGCTGGTCAAAGAGAGCAAGGATGCGATCGGGGATTTATTTTCTCAAATCACAGAGA
GCGCGCACACTGAAGAGGAACTCTCTAGCAAAGTGGAGCAGCTAAGCCGTAACGCTGATGATGTCAAATCCATTCTGGAT
ATTATCAATGATATTGCCGATCAAACGAATTTATTAGCCCTAAACGCTGCTATTGAAGCCGCAAGGGCTGGCGAGCATGG
CAGAGGCTTTGCGGTGGTGGCTGATGAAGTTAGGAATTTAGCCGGGCGCACTCAAAAGTCTTTAGCCGAAATCAATTCCA
CTATCATGGTGATTGTCCAAGAAATCAATGCCGTGAGTTCGCAAATGAATCTCAATTCGCAAAAAATGGAGCGTTTGAGC
GATATGAGTAAAAGCGTGCAAGAAACTTACGAAAAAATGAGTTCTAATTTAAGCTCAGTCGTGTCAGACAGCAATCAAAG
CATGGACGATTACGCCAAATCCGGACACCAAATTGAAGTTATGGTAAGCGATTTTGCAGAGGTGGAAAAAGTGGCTTCTA
AGACTTTAGCGGATTCTTCAGATATTTTAAACATCGCTACGCATGTGAGTGGAACGACCATGAATTTAGACAAACAAGTG
AATTTGTTTAAAACTTAA

Upstream 100 bases:

>100_bases
AATTTTGTTTTGTGCCACTCATTTTTCGGGGGGGGGGGGTGCATTTAGAAGCTAAACTCTAAAATTAGGGTTTGACTTAA
AAATGATTTATAGGAGATAA

Downstream 100 bases:

>100_bases
TCAGGGGGAGTTTATTAAAAAAGGGTTGGATTGTTAAAAGTTTCTGTGATCACGGCGTGTTTTAATAGCGAAAAAACCAT
TGAAGACACCATTCTTTCCG

Product: methyl-accepting chemotaxis protein (tlpB)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MMFSSMFASLGTRIMLVVLAALLGLGGLFIGFVKVMQKDVLAQLMEHLETGQYKKREKTLAYMTKIIEQGIHEYYKNFDN
ATARKMALDYFKRINDDKGMIYMVVVDKNGVVLFDPVNPKTVGQSGLDAQSVDGVYYVRGYLEAAKKGGGYTYYKMPKYD
GGVPEKKFAYSHYDEVSQMVIATTSYYTDINTENKAIKEGVNKVFDENTTKLFLWILTATIALVVLTLIYAKLRIVKRID
ELVLKINAFSRGDKDLRAKIDVGDRNDEISQVGRGINLFVENARLIMEEIKGISTLNKTSMDKLVQITQETQKSMKDSST
TLNSVKNKATDIASMMNASIEQSQGLRKRLIETQGLVKESKDAIGDLFSQITESAHTEEELSSKVEQLSRNADDVKSILD
IINDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINAVSSQMNLNSQKMERLS
DMSKSVQETYEKMSSNLSSVVSDSNQSMDDYAKSGHQIEVMVSDFAEVEKVASKTLADSSDILNIATHVSGTTMNLDKQV
NLFKT

Sequences:

>Translated_565_residues
MMFSSMFASLGTRIMLVVLAALLGLGGLFIGFVKVMQKDVLAQLMEHLETGQYKKREKTLAYMTKIIEQGIHEYYKNFDN
ATARKMALDYFKRINDDKGMIYMVVVDKNGVVLFDPVNPKTVGQSGLDAQSVDGVYYVRGYLEAAKKGGGYTYYKMPKYD
GGVPEKKFAYSHYDEVSQMVIATTSYYTDINTENKAIKEGVNKVFDENTTKLFLWILTATIALVVLTLIYAKLRIVKRID
ELVLKINAFSRGDKDLRAKIDVGDRNDEISQVGRGINLFVENARLIMEEIKGISTLNKTSMDKLVQITQETQKSMKDSST
TLNSVKNKATDIASMMNASIEQSQGLRKRLIETQGLVKESKDAIGDLFSQITESAHTEEELSSKVEQLSRNADDVKSILD
IINDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINAVSSQMNLNSQKMERLS
DMSKSVQETYEKMSSNLSSVVSDSNQSMDDYAKSGHQIEVMVSDFAEVEKVASKTLADSSDILNIATHVSGTTMNLDKQV
NLFKT
>Mature_565_residues
MMFSSMFASLGTRIMLVVLAALLGLGGLFIGFVKVMQKDVLAQLMEHLETGQYKKREKTLAYMTKIIEQGIHEYYKNFDN
ATARKMALDYFKRINDDKGMIYMVVVDKNGVVLFDPVNPKTVGQSGLDAQSVDGVYYVRGYLEAAKKGGGYTYYKMPKYD
GGVPEKKFAYSHYDEVSQMVIATTSYYTDINTENKAIKEGVNKVFDENTTKLFLWILTATIALVVLTLIYAKLRIVKRID
ELVLKINAFSRGDKDLRAKIDVGDRNDEISQVGRGINLFVENARLIMEEIKGISTLNKTSMDKLVQITQETQKSMKDSST
TLNSVKNKATDIASMMNASIEQSQGLRKRLIETQGLVKESKDAIGDLFSQITESAHTEEELSSKVEQLSRNADDVKSILD
IINDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINAVSSQMNLNSQKMERLS
DMSKSVQETYEKMSSNLSSVVSDSNQSMDDYAKSGHQIEVMVSDFAEVEKVASKTLADSSDILNIATHVSGTTMNLDKQV
NLFKT

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=261, Percent_Identity=30.2681992337165, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789453, Length=302, Percent_Identity=27.1523178807947, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788194, Length=178, Percent_Identity=33.1460674157303, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788195, Length=95, Percent_Identity=51.5789473684211, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787690, Length=331, Percent_Identity=28.0966767371601, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62791; Mature: 62791

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFSSMFASLGTRIMLVVLAALLGLGGLFIGFVKVMQKDVLAQLMEHLETGQYKKREKTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AYMTKIIEQGIHEYYKNFDNATARKMALDYFKRINDDKGMIYMVVVDKNGVVLFDPVNPK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCC
TVGQSGLDAQSVDGVYYVRGYLEAAKKGGGYTYYKMPKYDGGVPEKKFAYSHYDEVSQMV
CCCCCCCCCHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
IATTSYYTDINTENKAIKEGVNKVFDENTTKLFLWILTATIALVVLTLIYAKLRIVKRID
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVLKINAFSRGDKDLRAKIDVGDRNDEISQVGRGINLFVENARLIMEEIKGISTLNKTS
HHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHH
MDKLVQITQETQKSMKDSSTTLNSVKNKATDIASMMNASIEQSQGLRKRLIETQGLVKES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDAIGDLFSQITESAHTEEELSSKVEQLSRNADDVKSILDIINDIADQTNLLALNAAIEA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
ARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINAVSSQMNLNSQKMERLS
HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DMSKSVQETYEKMSSNLSSVVSDSNQSMDDYAKSGHQIEVMVSDFAEVEKVASKTLADSS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCH
DILNIATHVSGTTMNLDKQVNLFKT
HHHHHHHHCCCCEECCCCCCCCCCC
>Mature Secondary Structure
MMFSSMFASLGTRIMLVVLAALLGLGGLFIGFVKVMQKDVLAQLMEHLETGQYKKREKTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AYMTKIIEQGIHEYYKNFDNATARKMALDYFKRINDDKGMIYMVVVDKNGVVLFDPVNPK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCC
TVGQSGLDAQSVDGVYYVRGYLEAAKKGGGYTYYKMPKYDGGVPEKKFAYSHYDEVSQMV
CCCCCCCCCHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
IATTSYYTDINTENKAIKEGVNKVFDENTTKLFLWILTATIALVVLTLIYAKLRIVKRID
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVLKINAFSRGDKDLRAKIDVGDRNDEISQVGRGINLFVENARLIMEEIKGISTLNKTS
HHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHH
MDKLVQITQETQKSMKDSSTTLNSVKNKATDIASMMNASIEQSQGLRKRLIETQGLVKES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDAIGDLFSQITESAHTEEELSSKVEQLSRNADDVKSILDIINDIADQTNLLALNAAIEA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
ARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINAVSSQMNLNSQKMERLS
HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DMSKSVQETYEKMSSNLSSVVSDSNQSMDDYAKSGHQIEVMVSDFAEVEKVASKTLADSS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCH
DILNIATHVSGTTMNLDKQVNLFKT
HHHHHHHHCCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]