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The map label for this gene is rnpA

Identifier: 15618843

GI number: 15618843

Start: 1068523

End: 1068942

Strand: Reverse

Name: rnpA

Synonym: CPn0934

Alternate gene names: 15618843

Gene position: 1068942-1068523 (Counterclockwise)

Preceding gene: 15618844

Following gene: 15618841

Centisome position: 86.89

GC content: 44.29

Gene sequence:

>420_bases
GTGCACCCACTCACCTTACCAAAACAATCCCGCGTTTTGAAAAGAAAGCAATTTCTTTACATTACGCGTTCAGGTTTTTG
TTGTCGTGGTAGTCAGGCGACTTTCTACGTGGTCCCTTCTAGGCATCCCGGGACTTGTAGGATGGGTATTACTGTATCTA
AAAAATTTGGCAAAGCTCACGAAAGAAACTCTTTTAAACGTGTCGTTCGTGAAGTATTTCGGCATGTCCGCCACCAACTT
CCCAATTGTCAAATTGTTGTTTTCCCCAAGGGACATAAACAGCGCCCTGTCTTTTCAAAACTTCTCCAGGATTTTATAAA
TCAAATCCCAGAGGGGTTACATCGTCTTGGAAAAACGAAAGCTACGACTGGTGGCGAATGTACTCCAAAGAGCGAGAAAT
GTGTGACCGCACCTCGTTAG

Upstream 100 bases:

>100_bases
GTTTCCGTACTCGTATGGCCACAAGAAATGGAAGAAAACTTTTGAATCGTCGCCGCCGCCACGGTAGGCATTCCCTAGTC
GATTTATAATTTAGTATTTC

Downstream 100 bases:

>100_bases
GAGCAGCTTCAAAGGCAACCTCTGCATGTTGCAAAGCATGATGCCATTGATCAGAATCTAAGTAAAACTGCGCTATCATC
ATTTCTACACGCCACAAGTT

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MHPLTLPKQSRVLKRKQFLYITRSGFCCRGSQATFYVVPSRHPGTCRMGITVSKKFGKAHERNSFKRVVREVFRHVRHQL
PNCQIVVFPKGHKQRPVFSKLLQDFINQIPEGLHRLGKTKATTGGECTPKSEKCVTAPR

Sequences:

>Translated_139_residues
MHPLTLPKQSRVLKRKQFLYITRSGFCCRGSQATFYVVPSRHPGTCRMGITVSKKFGKAHERNSFKRVVREVFRHVRHQL
PNCQIVVFPKGHKQRPVFSKLLQDFINQIPEGLHRLGKTKATTGGECTPKSEKCVTAPR
>Mature_139_residues
MHPLTLPKQSRVLKRKQFLYITRSGFCCRGSQATFYVVPSRHPGTCRMGITVSKKFGKAHERNSFKRVVREVFRHVRHQL
PNCQIVVFPKGHKQRPVFSKLLQDFINQIPEGLHRLGKTKATTGGECTPKSEKCVTAPR

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_CHLPN (Q9Z6X2)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   D86607
- PIR:   H72016
- RefSeq:   NP_225129.1
- RefSeq:   NP_300991.1
- RefSeq:   NP_445464.1
- RefSeq:   NP_877240.1
- ProteinModelPortal:   Q9Z6X2
- SMR:   Q9Z6X2
- GeneID:   1467647
- GeneID:   895256
- GeneID:   919696
- GeneID:   963388
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0927
- KEGG:   cpn:CPn0934
- KEGG:   cpt:CpB0967
- TIGR:   CP_0927
- HOGENOM:   HBG728160
- OMA:   QFLYISR
- ProtClustDB:   PRK00730
- BioCyc:   CPNE115711:CP_0927-MONOMER
- BioCyc:   CPNE115713:CPN0934-MONOMER
- BioCyc:   CPNE138677:CPJ0934-MONOMER
- BioCyc:   CPNE182082:CPB0967-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 15927; Mature: 15927

Theoretical pI: Translated: 11.52; Mature: 11.52

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPLTLPKQSRVLKRKQFLYITRSGFCCRGSQATFYVVPSRHPGTCRMGITVSKKFGKAH
CCCCCCCHHHHHHHHHHEEEEECCCCEEECCCEEEEEEECCCCCCEEECEEECHHHCCHH
ERNSFKRVVREVFRHVRHQLPNCQIVVFPKGHKQRPVFSKLLQDFINQIPEGLHRLGKTK
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
ATTGGECTPKSEKCVTAPR
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHPLTLPKQSRVLKRKQFLYITRSGFCCRGSQATFYVVPSRHPGTCRMGITVSKKFGKAH
CCCCCCCHHHHHHHHHHEEEEECCCCEEECCCEEEEEEECCCCCCEEECEEECHHHCCHH
ERNSFKRVVREVFRHVRHQLPNCQIVVFPKGHKQRPVFSKLLQDFINQIPEGLHRLGKTK
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
ATTGGECTPKSEKCVTAPR
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362