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The map label for this gene is pgmA

Identifier: 15618772

GI number: 15618772

Start: 980828

End: 981514

Strand: Reverse

Name: pgmA

Synonym: CPn0863

Alternate gene names: 15618772

Gene position: 981514-980828 (Counterclockwise)

Preceding gene: 15618775

Following gene: 15618771

Centisome position: 79.78

GC content: 39.45

Gene sequence:

>687_bases
ATGGCTCTTCTTATTTTATTACGTCATGGACAATCTGTATGGAATGAAAAAAATTTATTTTCTGGATGGGTAGACATTCC
TTTAAGCCAACAGGGAATTGAAGAGGCTTTTTCCGCAGGAAGAGCTATTCAAAATTTGCCTATAGACTGCATCTTTACCT
CTACCTTAGTACGTAGTCTGATGACCGCCTTACTCGCCATGACAAATCATCACTCTAAGAAGATCCCCTATATTGTTCAT
GAAGATCCCAAAGCAAAAGAGATGTCGAGGATCTACAGTGCGGAAGAAGAAAACAATATGATTCCTCTCTATCAATCTAG
TGCCCTCAACGAAAGAATGTACGGCGAACTTCAAGGAAAAAATAAAAAACAAACAGCCGAACAGTTCGGAGAAGAGCGGG
TCAAGCTGTGGAGGCGCAGCTACAAAACAGCTCCTCCTCAGGGAGAAAGCCTCTATGATACGAAACAAAGGACCTTGCCT
TACTTTGAAAAAAATATTTTGCCTCAACTGCAAAATGGAAAAAACGTTTTTGTTTCTGCGCACGGAAATTCCTTACGCTC
TTTGATTATGGATCTAGAAAAATTAAGTGAGGAAGAGGTACTATCTTTAGAATTACCGACGGGAAAACCAGTTGTATATC
AATGGAAAAACCACAAAATCGAAAAGCACCCAGAATTTTTTGGTTAA

Upstream 100 bases:

>100_bases
TTCTTTGCTTAAAAACTTTTTTTACTTCTATATTTTCTACTAGACAAAAGTTGATTTCTGCTTATGCTTAGCTTCTCACC
CTAAATTCTAGTAGGAACAT

Downstream 100 bases:

>100_bases
ACAACCAAGTCGCTATTCCTCCTTCTGAGCGGGTTAAAGAAAGTTATGCCCTACACTCGGACATATTTTCTCTACCCCCC
GGCTCCGCGTTAAAATTAGC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MALLILLRHGQSVWNEKNLFSGWVDIPLSQQGIEEAFSAGRAIQNLPIDCIFTSTLVRSLMTALLAMTNHHSKKIPYIVH
EDPKAKEMSRIYSAEEENNMIPLYQSSALNERMYGELQGKNKKQTAEQFGEERVKLWRRSYKTAPPQGESLYDTKQRTLP
YFEKNILPQLQNGKNVFVSAHGNSLRSLIMDLEKLSEEEVLSLELPTGKPVVYQWKNHKIEKHPEFFG

Sequences:

>Translated_228_residues
MALLILLRHGQSVWNEKNLFSGWVDIPLSQQGIEEAFSAGRAIQNLPIDCIFTSTLVRSLMTALLAMTNHHSKKIPYIVH
EDPKAKEMSRIYSAEEENNMIPLYQSSALNERMYGELQGKNKKQTAEQFGEERVKLWRRSYKTAPPQGESLYDTKQRTLP
YFEKNILPQLQNGKNVFVSAHGNSLRSLIMDLEKLSEEEVLSLELPTGKPVVYQWKNHKIEKHPEFFG
>Mature_227_residues
ALLILLRHGQSVWNEKNLFSGWVDIPLSQQGIEEAFSAGRAIQNLPIDCIFTSTLVRSLMTALLAMTNHHSKKIPYIVHE
DPKAKEMSRIYSAEEENNMIPLYQSSALNERMYGELQGKNKKQTAEQFGEERVKLWRRSYKTAPPQGESLYDTKQRTLPY
FEKNILPQLQNGKNVFVSAHGNSLRSLIMDLEKLSEEEVLSLELPTGKPVVYQWKNHKIEKHPEFFG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=257, Percent_Identity=35.0194552529183, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI4505753, Length=258, Percent_Identity=37.2093023255814, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI4502445, Length=242, Percent_Identity=35.1239669421488, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI40353764, Length=242, Percent_Identity=35.1239669421488, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI71274132, Length=258, Percent_Identity=35.2713178294574, Blast_Score=138, Evalue=3e-33,
Organism=Escherichia coli, GI1786970, Length=238, Percent_Identity=35.7142857142857, Blast_Score=156, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6322697, Length=254, Percent_Identity=35.0393700787402, Blast_Score=153, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6320183, Length=265, Percent_Identity=27.1698113207547, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6324516, Length=263, Percent_Identity=28.1368821292776, Blast_Score=92, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24646216, Length=241, Percent_Identity=37.7593360995851, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI85725270, Length=243, Percent_Identity=36.2139917695473, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI85725272, Length=243, Percent_Identity=36.2139917695473, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24650981, Length=243, Percent_Identity=36.2139917695473, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571817, Length=242, Percent_Identity=28.5123966942149, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571815, Length=242, Percent_Identity=28.5123966942149, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24648979, Length=242, Percent_Identity=28.5123966942149, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_CHLPN (Q9Z743)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   E86598
- PIR:   G72025
- RefSeq:   NP_225058.1
- RefSeq:   NP_300920.1
- RefSeq:   NP_445543.1
- RefSeq:   NP_877164.1
- ProteinModelPortal:   Q9Z743
- SMR:   Q9Z743
- PHCI-2DPAGE:   Q9Z743
- GeneID:   1467571
- GeneID:   895583
- GeneID:   919626
- GeneID:   963479
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP1006
- KEGG:   cpn:CPn0863
- KEGG:   cpt:CpB0892
- TIGR:   CP_1006
- HOGENOM:   HBG658938
- OMA:   SDAAIME
- PhylomeDB:   Q9Z743
- ProtClustDB:   PRK01112
- BioCyc:   CPNE115711:CP_1006-MONOMER
- BioCyc:   CPNE115713:CPN0863-MONOMER
- BioCyc:   CPNE138677:CPJ0863-MONOMER
- BioCyc:   CPNE182082:CPB0892-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 26246; Mature: 26115

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 9-9 ACT_SITE 181-181

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLILLRHGQSVWNEKNLFSGWVDIPLSQQGIEEAFSAGRAIQNLPIDCIFTSTLVRSL
CEEEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHH
MTALLAMTNHHSKKIPYIVHEDPKAKEMSRIYSAEEENNMIPLYQSSALNERMYGELQGK
HHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCC
NKKQTAEQFGEERVKLWRRSYKTAPPQGESLYDTKQRTLPYFEKNILPQLQNGKNVFVSA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCEEEEEE
HGNSLRSLIMDLEKLSEEEVLSLELPTGKPVVYQWKNHKIEKHPEFFG
CCHHHHHHHHHHHHCCHHCEEEEECCCCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
ALLILLRHGQSVWNEKNLFSGWVDIPLSQQGIEEAFSAGRAIQNLPIDCIFTSTLVRSL
EEEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHH
MTALLAMTNHHSKKIPYIVHEDPKAKEMSRIYSAEEENNMIPLYQSSALNERMYGELQGK
HHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCC
NKKQTAEQFGEERVKLWRRSYKTAPPQGESLYDTKQRTLPYFEKNILPQLQNGKNVFVSA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCEEEEEE
HGNSLRSLIMDLEKLSEEEVLSLELPTGKPVVYQWKNHKIEKHPEFFG
CCHHHHHHHHHHHHCCHHCEEEEECCCCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362