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Identifier: 15618765

GI number: 15618765

Start: 973992

End: 975377

Strand: Reverse

Name: Not Available

Synonym: CPn0856

Alternate gene names: NA

Gene position: 975377-973992 (Counterclockwise)

Preceding gene: 15618766

Following gene: 15618764

Centisome position: 79.28

GC content: 42.06

Gene sequence:

>1386_bases
ATGACTGAATCGGTATATTCGCCCTCTGCTATGCATGTAAACTCTCTAGCAGATAAGCTCAAAGCCATAAATCAAGAACA
TATATTAGATATCTGGCCCTCCCTTTCTCCAAAACAACAACAAAGACTTTTTCAGCAGCTCACCTCTGTAGATATTGATT
TTTTTCGTAAGCAACAGCAACTGCTTTCCTCACCAACAGCAATTCTTAAAGATTTTCATCCGATAACGTCATTTGCCTCT
TCAGGAGAAGATCCAGAACGAGCTCATGCAGGAACTACGCTACTTAAAGAGAAAAAAGTTGCCTGTGTAGTCCTGGCAGG
GGGACAAGGCTCAAGATTGAAGTGCGATGGCCCTAAAGGGTTATTCCCTGTTTCTCCTATTAAAAAGAAGCCGCTGTTTC
AGTTGGTAGCAGAAAAGGTACGTGCTGCAAGTAAACTTGCAGGTCAACCTCTTCCTCTAGCATTCATGACCTCTCCTTTG
AATACCCGACAAACACGTTCTTTTTTTGAATCCAACGACTACTTCCACCTAGATCCAAATCAGGTGGATTTTTTCTGCCA
ACCACTTTGGCCCCTCCTCACCCTATCTGGAGACCTATTTCTTGAAGATATGGACACTCTAGCTCTTGGTCCGAATGGCA
ACGGTTGTATAGCTACCCTTCTCTATACTTCAGGAGTATGGGAGAAATGGAAAAATGCTGGCATAGAAATGGTAAGTGTG
ATCCCCATTGACAATCCTTTAGCGCTTCCTTTTGACGTAGAACTCTGTGGATTCCATGCGATGTCTAACAACGAGGTAAC
CATAAAAGCGGCTCTACGTCAAACTGCTATTGAAGATGTGGGTATTCTTGTAAAATCTCATGATTCTGGAAAAACTTCTG
TTATCGAATACTCTGAAATTCCCCAAAACGAGAGATTCGCTCTTAATGAAGATGGAAAATTAAAATACTGCCTTGCAAAT
ATCGGTCTTTACTGTCTCTCCATGGACTTTATCCGCCACGCCGCCTACCAACAGCTGCCCCTGTATAAAGTCCACAAGCA
TGCCAAGCAACTAGGCCATACCTCCTTAAATGAGAAAAATGCTTGGAAATTTGAAGAGTTTATCTTTGATCTATTTTGTT
ATAGCGACCATTGTCAAACTCTTGTGTATCCTAGACAAGAGTGCTTTGCTCCCCTAAAAAATCTGGAGGGCAATCATAGC
CCCGATACAGTAAGACAAGCTCTCTCTGACCGAGAGCGCCAACTCTTCCACAAAGTCACAGGAAAAAAGCTCTCTCCTAA
CACAACATTTGAATTAGAAGCTGATTTTTATTATCCTTCAACATCAACTTCCCTACATTGGGAAAACAAAGCATTTTTCG
AGGAACCATTTTTTGAGGCCTCATGA

Upstream 100 bases:

>100_bases
AACAACTCCAGGAATTAATAAACCGCAGAAAAATCATCGAAAAGATCAAGAACAATAAGTATTCTAAGGATCAAGAGATA
GGAACGTAAGGCTAACTGTA

Downstream 100 bases:

>100_bases
AACAACACATCGGCTACTTAGGTATGGGAATTTGGGGGTTTTGTCTAGCCTCCCTACTTGCGAATAAGGGATATCCTGTT
GTGGCATGGTCCCGGAACCC

Product: UDP-glucose pyrophosphorylase

Products: diphosphate; UDP-N-acetyl-D-glucosamine

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTESVYSPSAMHVNSLADKLKAINQEHILDIWPSLSPKQQQRLFQQLTSVDIDFFRKQQQLLSSPTAILKDFHPITSFAS
SGEDPERAHAGTTLLKEKKVACVVLAGGQGSRLKCDGPKGLFPVSPIKKKPLFQLVAEKVRAASKLAGQPLPLAFMTSPL
NTRQTRSFFESNDYFHLDPNQVDFFCQPLWPLLTLSGDLFLEDMDTLALGPNGNGCIATLLYTSGVWEKWKNAGIEMVSV
IPIDNPLALPFDVELCGFHAMSNNEVTIKAALRQTAIEDVGILVKSHDSGKTSVIEYSEIPQNERFALNEDGKLKYCLAN
IGLYCLSMDFIRHAAYQQLPLYKVHKHAKQLGHTSLNEKNAWKFEEFIFDLFCYSDHCQTLVYPRQECFAPLKNLEGNHS
PDTVRQALSDRERQLFHKVTGKKLSPNTTFELEADFYYPSTSTSLHWENKAFFEEPFFEAS

Sequences:

>Translated_461_residues
MTESVYSPSAMHVNSLADKLKAINQEHILDIWPSLSPKQQQRLFQQLTSVDIDFFRKQQQLLSSPTAILKDFHPITSFAS
SGEDPERAHAGTTLLKEKKVACVVLAGGQGSRLKCDGPKGLFPVSPIKKKPLFQLVAEKVRAASKLAGQPLPLAFMTSPL
NTRQTRSFFESNDYFHLDPNQVDFFCQPLWPLLTLSGDLFLEDMDTLALGPNGNGCIATLLYTSGVWEKWKNAGIEMVSV
IPIDNPLALPFDVELCGFHAMSNNEVTIKAALRQTAIEDVGILVKSHDSGKTSVIEYSEIPQNERFALNEDGKLKYCLAN
IGLYCLSMDFIRHAAYQQLPLYKVHKHAKQLGHTSLNEKNAWKFEEFIFDLFCYSDHCQTLVYPRQECFAPLKNLEGNHS
PDTVRQALSDRERQLFHKVTGKKLSPNTTFELEADFYYPSTSTSLHWENKAFFEEPFFEAS
>Mature_460_residues
TESVYSPSAMHVNSLADKLKAINQEHILDIWPSLSPKQQQRLFQQLTSVDIDFFRKQQQLLSSPTAILKDFHPITSFASS
GEDPERAHAGTTLLKEKKVACVVLAGGQGSRLKCDGPKGLFPVSPIKKKPLFQLVAEKVRAASKLAGQPLPLAFMTSPLN
TRQTRSFFESNDYFHLDPNQVDFFCQPLWPLLTLSGDLFLEDMDTLALGPNGNGCIATLLYTSGVWEKWKNAGIEMVSVI
PIDNPLALPFDVELCGFHAMSNNEVTIKAALRQTAIEDVGILVKSHDSGKTSVIEYSEIPQNERFALNEDGKLKYCLANI
GLYCLSMDFIRHAAYQQLPLYKVHKHAKQLGHTSLNEKNAWKFEEFIFDLFCYSDHCQTLVYPRQECFAPLKNLEGNHSP
DTVRQALSDRERQLFHKVTGKKLSPNTTFELEADFYYPSTSTSLHWENKAFFEEPFFEAS

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 1 family [H]

Homologues:

Organism=Homo sapiens, GI187936958, Length=420, Percent_Identity=30.952380952381, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI156627575, Length=427, Percent_Identity=27.8688524590164, Blast_Score=166, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17552518, Length=431, Percent_Identity=25.9860788863109, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI193206427, Length=339, Percent_Identity=26.5486725663717, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320100, Length=421, Percent_Identity=29.6912114014252, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19920822, Length=478, Percent_Identity=25.7322175732218, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24582229, Length=470, Percent_Identity=25.7446808510638, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002618 [H]

Pfam domain/function: PF01704 UDPGP [H]

EC number: 2.7.7.23

Molecular weight: Translated: 51991; Mature: 51860

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESVYSPSAMHVNSLADKLKAINQEHILDIWPSLSPKQQQRLFQQLTSVDIDFFRKQQQ
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
LLSSPTAILKDFHPITSFASSGEDPERAHAGTTLLKEKKVACVVLAGGQGSRLKCDGPKG
HHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCC
LFPVSPIKKKPLFQLVAEKVRAASKLAGQPLPLAFMTSPLNTRQTRSFFESNDYFHLDPN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHCCCEEEECCC
QVDFFCQPLWPLLTLSGDLFLEDMDTLALGPNGNGCIATLLYTSGVWEKWKNAGIEMVSV
CCHHHHCCHHHHHHCCCCEEEECCCCEEECCCCCCEEEEEEHHHHHHHHHHCCCCEEEEE
IPIDNPLALPFDVELCGFHAMSNNEVTIKAALRQTAIEDVGILVKSHDSGKTSVIEYSEI
EECCCCCCCCEEEHEEEEEEECCCCEEEHHHHHHHHHHHHEEEEEECCCCCCEEEEHHHC
PQNERFALNEDGKLKYCLANIGLYCLSMDFIRHAAYQQLPLYKVHKHAKQLGHTSLNEKN
CCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
AWKFEEFIFDLFCYSDHCQTLVYPRQECFAPLKNLEGNHSPDTVRQALSDRERQLFHKVT
CHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
GKKLSPNTTFELEADFYYPSTSTSLHWENKAFFEEPFFEAS
CCCCCCCCEEEEEEEEECCCCCCEEEECCCCHHCCCCCCCC
>Mature Secondary Structure 
TESVYSPSAMHVNSLADKLKAINQEHILDIWPSLSPKQQQRLFQQLTSVDIDFFRKQQQ
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
LLSSPTAILKDFHPITSFASSGEDPERAHAGTTLLKEKKVACVVLAGGQGSRLKCDGPKG
HHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCC
LFPVSPIKKKPLFQLVAEKVRAASKLAGQPLPLAFMTSPLNTRQTRSFFESNDYFHLDPN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHCCCEEEECCC
QVDFFCQPLWPLLTLSGDLFLEDMDTLALGPNGNGCIATLLYTSGVWEKWKNAGIEMVSV
CCHHHHCCHHHHHHCCCCEEEECCCCEEECCCCCCEEEEEEHHHHHHHHHHCCCCEEEEE
IPIDNPLALPFDVELCGFHAMSNNEVTIKAALRQTAIEDVGILVKSHDSGKTSVIEYSEI
EECCCCCCCCEEEHEEEEEEECCCCEEEHHHHHHHHHHHHEEEEEECCCCCCEEEEHHHC
PQNERFALNEDGKLKYCLANIGLYCLSMDFIRHAAYQQLPLYKVHKHAKQLGHTSLNEKN
CCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
AWKFEEFIFDLFCYSDHCQTLVYPRQECFAPLKNLEGNHSPDTVRQALSDRERQLFHKVT
CHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
GKKLSPNTTFELEADFYYPSTSTSLHWENKAFFEEPFFEAS
CCCCCCCCEEEEEEEEECCCCCCEEEECCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; N-acetyl-alpha-D-glucosamine 1-phosphate

Specific reaction: UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-glucosamine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA