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The map label for this gene is sohB

Identifier: 15618523

GI number: 15618523

Start: 704655

End: 705656

Strand: Reverse

Name: sohB

Synonym: CPn0613

Alternate gene names: 15618523

Gene position: 705656-704655 (Counterclockwise)

Preceding gene: 15618524

Following gene: 15618522

Centisome position: 57.36

GC content: 41.62

Gene sequence:

>1002_bases
ATGAAAACGTTGTGGCACTTCGTATCCAAAGCCTTTTTATCGATAGTAGGACTGTGTTGCGGAGTTGTTCTTGCTTTTGT
CGTTATATTCGCACTCATAGCTTCCTCTTTAGGAAATGGGGATGCTACCTTCGTTAGCTTGCCTGACGCCCAAGGAGAAG
TAAAAGATCTAGGGAAAACAGCCCCCATTATTGCTGTTATCGAAATGAAAGATGTAATTGCTTCTTCAAAAAATACGGCC
AAAACGATTCAGAATATTTTAGAAGGATTTGAGAAAGCTCCTCTTAAAGATCGTGTCAAAGGTATTGTCATTGATATGGA
TTGCCCAGGAGGCGAGGTCTTTGAAATAGATAGAATTTACTCTATGCTTCGCTTTTGGAAAGAACGTAAGGGATTCCCTA
TTTATATTTATGTGAATGGTCTTTGTGCTTCGGGAGGCTATTATGTATCCTGCGCTGCAACTAAAATTTATGCCACCTCC
TCCTCTCTTATCGGTTCTATCGGAGTGCGTTCTGGACCATTCTTCAATGTAAAAGAAGGTTTAAATCGCTACGGAGTTGA
AAGTGATCTGCTGACAGCTGGAAAAGATAAGGCTCCAATGAATCCTTATACACCGTGGACTTCTCATGATAGAGAAGAAC
GGCAAGCGACTCTTGATTTTCTCTACGGACAATTTGTTGATATAGTTACACAAAACCGTCCTCTGCTTACTAAAGAGAAG
TTAGTTCACACTCTCGGAGCACGTATTTTTTCTCCAGAGAAGGCCAAACAAGAAGGCTATATTGATGTTGTAGGCGCAAC
TAAAGAACAAGTCCTTCAAGACATAGTTGCTGTTTGTAAGATTGAAGATAACTATAGAGTGATTGGCTCTGGTGGTGATG
GTTGGTGGAAGCGGGTGGCTTCAGCTGCAGCTTCAAGTCCATTAGTTACTGGCATGATTAAACACGATATTCTGCCTTTA
TCCCATGACGCTGCATACATACCTCCCTACTTGGCACTGTAG

Upstream 100 bases:

>100_bases
TTCTCGGTGAGCATGAGAATTTTATAATTTTCATCTTTAAGCTTTTCTGCTCATCCCTTATTTTATCCATTTTAGAATTT
ACTAGAATTTATAGGTCGTT

Downstream 100 bases:

>100_bases
AGAGACCTAGAAGGGAATATGCAATGAAGAAACTGTTTGTATTAGATGCCTCAGGATTTATCTTTCGTGCCTACTTTGCT
TTGCCAGAAATGAAAAATCA

Product: protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKTLWHFVSKAFLSIVGLCCGVVLAFVVIFALIASSLGNGDATFVSLPDAQGEVKDLGKTAPIIAVIEMKDVIASSKNTA
KTIQNILEGFEKAPLKDRVKGIVIDMDCPGGEVFEIDRIYSMLRFWKERKGFPIYIYVNGLCASGGYYVSCAATKIYATS
SSLIGSIGVRSGPFFNVKEGLNRYGVESDLLTAGKDKAPMNPYTPWTSHDREERQATLDFLYGQFVDIVTQNRPLLTKEK
LVHTLGARIFSPEKAKQEGYIDVVGATKEQVLQDIVAVCKIEDNYRVIGSGGDGWWKRVASAAASSPLVTGMIKHDILPL
SHDAAYIPPYLAL

Sequences:

>Translated_333_residues
MKTLWHFVSKAFLSIVGLCCGVVLAFVVIFALIASSLGNGDATFVSLPDAQGEVKDLGKTAPIIAVIEMKDVIASSKNTA
KTIQNILEGFEKAPLKDRVKGIVIDMDCPGGEVFEIDRIYSMLRFWKERKGFPIYIYVNGLCASGGYYVSCAATKIYATS
SSLIGSIGVRSGPFFNVKEGLNRYGVESDLLTAGKDKAPMNPYTPWTSHDREERQATLDFLYGQFVDIVTQNRPLLTKEK
LVHTLGARIFSPEKAKQEGYIDVVGATKEQVLQDIVAVCKIEDNYRVIGSGGDGWWKRVASAAASSPLVTGMIKHDILPL
SHDAAYIPPYLAL
>Mature_333_residues
MKTLWHFVSKAFLSIVGLCCGVVLAFVVIFALIASSLGNGDATFVSLPDAQGEVKDLGKTAPIIAVIEMKDVIASSKNTA
KTIQNILEGFEKAPLKDRVKGIVIDMDCPGGEVFEIDRIYSMLRFWKERKGFPIYIYVNGLCASGGYYVSCAATKIYATS
SSLIGSIGVRSGPFFNVKEGLNRYGVESDLLTAGKDKAPMNPYTPWTSHDREERQATLDFLYGQFVDIVTQNRPLLTKEK
LVHTLGARIFSPEKAKQEGYIDVVGATKEQVLQDIVAVCKIEDNYRVIGSGGDGWWKRVASAAASSPLVTGMIKHDILPL
SHDAAYIPPYLAL

Specific function: Digestion of cleaved signal peptides. Required for efficient processing of precursors under conditions of hyper-secretion [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=216, Percent_Identity=27.3148148148148, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788064, Length=176, Percent_Identity=28.9772727272727, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 36369; Mature: 36369

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLWHFVSKAFLSIVGLCCGVVLAFVVIFALIASSLGNGDATFVSLPDAQGEVKDLGKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCC
APIIAVIEMKDVIASSKNTAKTIQNILEGFEKAPLKDRVKGIVIDMDCPGGEVFEIDRIY
CCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHCEEEEEECCCCCCEEEHHHHH
SMLRFWKERKGFPIYIYVNGLCASGGYYVSCAATKIYATSSSLIGSIGVRSGPFFNVKEG
HHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEEEEEEECCHHHHHHCCCCCCCCCCHHHH
LNRYGVESDLLTAGKDKAPMNPYTPWTSHDREERQATLDFLYGQFVDIVTQNRPLLTKEK
HHHCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LVHTLGARIFSPEKAKQEGYIDVVGATKEQVLQDIVAVCKIEDNYRVIGSGGDGWWKRVA
HHHHHHHHHCCCHHHHHCCCEEEECCCHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHH
SAAASSPLVTGMIKHDILPLSHDAAYIPPYLAL
HHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHCC
>Mature Secondary Structure
MKTLWHFVSKAFLSIVGLCCGVVLAFVVIFALIASSLGNGDATFVSLPDAQGEVKDLGKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCC
APIIAVIEMKDVIASSKNTAKTIQNILEGFEKAPLKDRVKGIVIDMDCPGGEVFEIDRIY
CCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHCEEEEEECCCCCCEEEHHHHH
SMLRFWKERKGFPIYIYVNGLCASGGYYVSCAATKIYATSSSLIGSIGVRSGPFFNVKEG
HHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEEEEEEECCHHHHHHCCCCCCCCCCHHHH
LNRYGVESDLLTAGKDKAPMNPYTPWTSHDREERQATLDFLYGQFVDIVTQNRPLLTKEK
HHHCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LVHTLGARIFSPEKAKQEGYIDVVGATKEQVLQDIVAVCKIEDNYRVIGSGGDGWWKRVA
HHHHHHHHHCCCHHHHHCCCEEEECCCHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHH
SAAASSPLVTGMIKHDILPLSHDAAYIPPYLAL
HHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10455123 [H]