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Identifier: 15618312

GI number: 15618312

Start: 444378

End: 445115

Strand: Reverse

Name: Not Available

Synonym: CPn0397

Alternate gene names: 15618312

Gene position: 445115-444378 (Counterclockwise)

Preceding gene: 15618316

Following gene: 15618311

Centisome position: 36.18

GC content: 44.04

Gene sequence:

>738_bases
GTGGATTTTGATTATTTTGGTCTGAGTGATATTGGTAGGGTGCGCGCTAGAAATGAAGATTTTTGGCAGGTAAACCTCAT
GTCTCAAGTGGTTGCTATTGCTGACGGTGTTGGGGGGCGTCTTGGTGGAGACATTGCTTCTCAAGAGGCAGTGACTAGCC
TTATGGAGCTGATTGATGAGCAACAGTCAAAATTGATGGGGTATGGGGATGACCAGTATAAGGAGACTTTAAAAAAGATC
CTTTTAGAGGTCAATGGTGTGGTCTATGAACACGGCCAAATGGAAGAGCATCTCCAGGGTATGGGAACCACTCTTAGCTT
CATCCAATTCCGGAAGGATAGGGCATGGCTATTTCATGTGGGAGATAGTCGAATTTATCGTATTCGTGAGGGAGAACTGC
GCCGCCTTACCGAAGACCATTCTTTAGAAAATCAATTAAAAAATCGTTATGGGCTTCCTAAACAATCAGATAAGGTGTAT
TCTTATCGCCATATTCTGACTAATGTTTTGGGAAGTCGTCCCTATGTCATGCCTGACATTCGGAATCTTCCTTGTGAAAA
GGAAGATTTGTACTGCCTCTGTTCGGATGGATTGACAAACATGGTTCCAGATATCGATATTCGTGATATCTTGAACCAGC
CCGCCACCCTAGAAGAACGGGGGAATGCATTAATTTCTCTAGCCAATACTCGTGGAGGCGATGACAACGCTACTGTCGTA
TTAGTCCGAATACAATAG

Upstream 100 bases:

>100_bases
CGTCAGGAAAATTCAATTCTTTATAATAATGATATGAAATTAGAGAATGTCTATAGGGGCGGACTCTATTTGTGATCCAG
GATCTCTTTAGGAGCACTTT

Downstream 100 bases:

>100_bases
TTCCTTTGCTAAGGATAGTATTCCATGATCTATTTGGATAACAATGCGATGACACCCCCAGAGAGGGGACTTTTGGAATT
TCTCCAAAAAACCTTCCTTA

Product: PP2C phosphatase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MDFDYFGLSDIGRVRARNEDFWQVNLMSQVVAIADGVGGRLGGDIASQEAVTSLMELIDEQQSKLMGYGDDQYKETLKKI
LLEVNGVVYEHGQMEEHLQGMGTTLSFIQFRKDRAWLFHVGDSRIYRIREGELRRLTEDHSLENQLKNRYGLPKQSDKVY
SYRHILTNVLGSRPYVMPDIRNLPCEKEDLYCLCSDGLTNMVPDIDIRDILNQPATLEERGNALISLANTRGGDDNATVV
LVRIQ

Sequences:

>Translated_245_residues
MDFDYFGLSDIGRVRARNEDFWQVNLMSQVVAIADGVGGRLGGDIASQEAVTSLMELIDEQQSKLMGYGDDQYKETLKKI
LLEVNGVVYEHGQMEEHLQGMGTTLSFIQFRKDRAWLFHVGDSRIYRIREGELRRLTEDHSLENQLKNRYGLPKQSDKVY
SYRHILTNVLGSRPYVMPDIRNLPCEKEDLYCLCSDGLTNMVPDIDIRDILNQPATLEERGNALISLANTRGGDDNATVV
LVRIQ
>Mature_245_residues
MDFDYFGLSDIGRVRARNEDFWQVNLMSQVVAIADGVGGRLGGDIASQEAVTSLMELIDEQQSKLMGYGDDQYKETLKKI
LLEVNGVVYEHGQMEEHLQGMGTTLSFIQFRKDRAWLFHVGDSRIYRIREGELRRLTEDHSLENQLKNRYGLPKQSDKVY
SYRHILTNVLGSRPYVMPDIRNLPCEKEDLYCLCSDGLTNMVPDIDIRDILNQPATLEERGNALISLANTRGGDDNATVV
LVRIQ

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 27904; Mature: 27904

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDYFGLSDIGRVRARNEDFWQVNLMSQVVAIADGVGGRLGGDIASQEAVTSLMELIDE
CCCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
QQSKLMGYGDDQYKETLKKILLEVNGVVYEHGQMEEHLQGMGTTLSFIQFRKDRAWLFHV
HHHHHCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHCCCHHHHHHHHCCCEEEEEE
GDSRIYRIREGELRRLTEDHSLENQLKNRYGLPKQSDKVYSYRHILTNVLGSRPYVMPDI
CCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCC
RNLPCEKEDLYCLCSDGLTNMVPDIDIRDILNQPATLEERGNALISLANTRGGDDNATVV
CCCCCCCCCCEEEECCCHHHHCCCCCHHHHHCCCCCHHHCCCEEEEEECCCCCCCCEEEE
LVRIQ
EEEEC
>Mature Secondary Structure
MDFDYFGLSDIGRVRARNEDFWQVNLMSQVVAIADGVGGRLGGDIASQEAVTSLMELIDE
CCCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
QQSKLMGYGDDQYKETLKKILLEVNGVVYEHGQMEEHLQGMGTTLSFIQFRKDRAWLFHV
HHHHHCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHCCCHHHHHHHHCCCEEEEEE
GDSRIYRIREGELRRLTEDHSLENQLKNRYGLPKQSDKVYSYRHILTNVLGSRPYVMPDI
CCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCC
RNLPCEKEDLYCLCSDGLTNMVPDIDIRDILNQPATLEERGNALISLANTRGGDDNATVV
CCCCCCCCCCEEEECCCHHHHCCCCCHHHHHCCCCCHHHCCCEEEEEECCCCCCCCEEEE
LVRIQ
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]