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The map label for this gene is dnaA

Identifier: 15618229

GI number: 15618229

Start: 349592

End: 350974

Strand: Reverse

Name: dnaA

Synonym: CPn0309

Alternate gene names: 15618229

Gene position: 350974-349592 (Counterclockwise)

Preceding gene: 15618230

Following gene: 15618227

Centisome position: 28.53

GC content: 37.31

Gene sequence:

>1383_bases
ATGCGAGCATGGGAAGAATTTCTTTTGCTACAAGAGAAAGAAATTGGCACAAATACTGTAGACAAGTGGTTGCGATCTTT
AAAGGTCTTATGTTTTGATGCTTGTAATTTGTATCTTGAAGCTCAAGATTCTTTTCAAATTACTTGGTTTGAGGAGCATA
TAAGACATAAGGTTAAATCTGGTCTTGTAAATAATAACAATAAGCCCATTCGTGTTCACGTTACTTCGGTAGATAAAGCA
GCTCCTTTTTATAAGGAGAAGCAGATGCAGCAAGAGAAGACAGCATACTTTACCATGCATTATGGAAGTGTGAATCCTGA
GATGACCTTCTCTAATTTTTTAGTTACCCCTGAAAATGATCTTCCTTTTCGTGTTTTACAGGAATTTACTAAGAGTCCTG
ATGAAAACGGAGGAGTTACTTTTAATCCAATTTATCTGTTTGGACCTGAGGGATCTGGAAAAACTCACTTAATGCAGTCA
GCTATCAGTGTTCTTCGTGAATCTGGAGGTAAGATTCTCTATGTTTCTTCGGATTTGTTTACAGAGCACTTAGTCTCTGC
TATCCGTTCAGGAGAAATGCAAAAATTCCGTTCTTTTTACCGCAATATTGATGCTCTATTCATTGAGGATATCGAGGTTT
TTTCAGGAAAGTCGGCAACTCAAGAAGAGTTCTTCCATACGTTTAATTCTCTTCATTCTGAAGGGAAGTTGATTGTAGTG
TCTTCATCCTATGCGCCTGTGGATCTCGTTGCTGTTGAAGATAGATTGATCAGCAGGTTTGAATGGGGAGTTGCAATTCC
GATACATCCTTTGGTTCAGGAAGGATTGCGCAGTTTCTTAATGAGACAGGTAGAGCGCTTATCTATTCGCATTCAAGAAA
CGGCCTTAGATTTTTTAATTTATGCGCTATCTTCCAACGTAAAGACCTTACTGCATGCACTGAATCTTTTAGCAAAGAGG
GTAATGTATAAAAAACTCTCTCACCAATTACTATATGAAGATGATGTGAAAACTCTTTTAAAAGATGTTTTAGAAGCAGC
AGGAAGCGTTCGTTTAACTCCTTTAAAGATTATTCGTAATGTTGCTCAATATTATGGGGTCTCTCAGGAGAGTATTTTAG
GACGTTCTCAGTCCCGAGAATATGTATTGCCACGTCAGGTAGCCATGTACTTTTGTCGTCAGAAGCTTTCACTATCATAC
GTGAGAATAGGCGATGTCTTTTCAAGAGATCATTCGACGGTAATCTCATCCATACGATTGATTGAACAAAAAATAGAAGA
AAATAGCCATGATATTCACATGGCTATTCAAGATATTTCTAAGAATTTAAATTCCTTGCATAAGAGTTTGGAATTTTTCC
CTAGCGAAGAGATGATTATTTAG

Upstream 100 bases:

>100_bases
TGGTTTTAAATAATAAAAAACATCGATAATACTGAAAAAAAAGTCGAATTGTCTTAATACAGGCTTATTGAAACAAGCGA
TTTATATGAGCTCATAGTTT

Downstream 100 bases:

>100_bases
AGGAGTAACGATCCTCTAATTTTTGCTTCTGGACAGTTGCAGCAGCCGGCGCAGATATCATTTTCATTGAGTTCAACTCC
GCTGTTCTAGCTTGTTTAAA

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MRAWEEFLLLQEKEIGTNTVDKWLRSLKVLCFDACNLYLEAQDSFQITWFEEHIRHKVKSGLVNNNNKPIRVHVTSVDKA
APFYKEKQMQQEKTAYFTMHYGSVNPEMTFSNFLVTPENDLPFRVLQEFTKSPDENGGVTFNPIYLFGPEGSGKTHLMQS
AISVLRESGGKILYVSSDLFTEHLVSAIRSGEMQKFRSFYRNIDALFIEDIEVFSGKSATQEEFFHTFNSLHSEGKLIVV
SSSYAPVDLVAVEDRLISRFEWGVAIPIHPLVQEGLRSFLMRQVERLSIRIQETALDFLIYALSSNVKTLLHALNLLAKR
VMYKKLSHQLLYEDDVKTLLKDVLEAAGSVRLTPLKIIRNVAQYYGVSQESILGRSQSREYVLPRQVAMYFCRQKLSLSY
VRIGDVFSRDHSTVISSIRLIEQKIEENSHDIHMAIQDISKNLNSLHKSLEFFPSEEMII

Sequences:

>Translated_460_residues
MRAWEEFLLLQEKEIGTNTVDKWLRSLKVLCFDACNLYLEAQDSFQITWFEEHIRHKVKSGLVNNNNKPIRVHVTSVDKA
APFYKEKQMQQEKTAYFTMHYGSVNPEMTFSNFLVTPENDLPFRVLQEFTKSPDENGGVTFNPIYLFGPEGSGKTHLMQS
AISVLRESGGKILYVSSDLFTEHLVSAIRSGEMQKFRSFYRNIDALFIEDIEVFSGKSATQEEFFHTFNSLHSEGKLIVV
SSSYAPVDLVAVEDRLISRFEWGVAIPIHPLVQEGLRSFLMRQVERLSIRIQETALDFLIYALSSNVKTLLHALNLLAKR
VMYKKLSHQLLYEDDVKTLLKDVLEAAGSVRLTPLKIIRNVAQYYGVSQESILGRSQSREYVLPRQVAMYFCRQKLSLSY
VRIGDVFSRDHSTVISSIRLIEQKIEENSHDIHMAIQDISKNLNSLHKSLEFFPSEEMII
>Mature_460_residues
MRAWEEFLLLQEKEIGTNTVDKWLRSLKVLCFDACNLYLEAQDSFQITWFEEHIRHKVKSGLVNNNNKPIRVHVTSVDKA
APFYKEKQMQQEKTAYFTMHYGSVNPEMTFSNFLVTPENDLPFRVLQEFTKSPDENGGVTFNPIYLFGPEGSGKTHLMQS
AISVLRESGGKILYVSSDLFTEHLVSAIRSGEMQKFRSFYRNIDALFIEDIEVFSGKSATQEEFFHTFNSLHSEGKLIVV
SSSYAPVDLVAVEDRLISRFEWGVAIPIHPLVQEGLRSFLMRQVERLSIRIQETALDFLIYALSSNVKTLLHALNLLAKR
VMYKKLSHQLLYEDDVKTLLKDVLEAAGSVRLTPLKIIRNVAQYYGVSQESILGRSQSREYVLPRQVAMYFCRQKLSLSY
VRIGDVFSRDHSTVISSIRLIEQKIEENSHDIHMAIQDISKNLNSLHKSLEFFPSEEMII

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=473, Percent_Identity=29.8097251585624, Blast_Score=208, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA1_CHLPN (Q9Z8M9)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   E86529
- PIR:   F72092
- RefSeq:   NP_224514.1
- RefSeq:   NP_300368.1
- RefSeq:   NP_444997.1
- RefSeq:   NP_876594.1
- ProteinModelPortal:   Q9Z8M9
- SMR:   Q9Z8M9
- GeneID:   1467001
- GeneID:   895122
- GeneID:   919087
- GeneID:   963292
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0449
- KEGG:   cpn:CPn0309
- KEGG:   cpt:CpB0317
- TIGR:   CP_0449
- HOGENOM:   HBG414010
- OMA:   ENDLPFR
- ProtClustDB:   PRK12422
- BioCyc:   CPNE115711:CP_0449-MONOMER
- BioCyc:   CPNE115713:CPN0309-MONOMER
- BioCyc:   CPNE138677:CPJ0309-MONOMER
- BioCyc:   CPNE182082:CPB0317-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 52941; Mature: 52941

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAWEEFLLLQEKEIGTNTVDKWLRSLKVLCFDACNLYLEAQDSFQITWFEEHIRHKVKS
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEEHHHHHHHHHHH
GLVNNNNKPIRVHVTSVDKAAPFYKEKQMQQEKTAYFTMHYGSVNPEMTFSNFLVTPEND
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCEECCEEECCCCC
LPFRVLQEFTKSPDENGGVTFNPIYLFGPEGSGKTHLMQSAISVLRESGGKILYVSSDLF
CCHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHH
TEHLVSAIRSGEMQKFRSFYRNIDALFIEDIEVFSGKSATQEEFFHTFNSLHSEGKLIVV
HHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEE
SSSYAPVDLVAVEDRLISRFEWGVAIPIHPLVQEGLRSFLMRQVERLSIRIQETALDFLI
ECCCCCEEEEEHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALSSNVKTLLHALNLLAKRVMYKKLSHQLLYEDDVKTLLKDVLEAAGSVRLTPLKIIRN
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHH
VAQYYGVSQESILGRSQSREYVLPRQVAMYFCRQKLSLSYVRIGDVFSRDHSTVISSIRL
HHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHHCHHHHHHHHHHH
IEQKIEENSHDIHMAIQDISKNLNSLHKSLEFFPSEEMII
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRAWEEFLLLQEKEIGTNTVDKWLRSLKVLCFDACNLYLEAQDSFQITWFEEHIRHKVKS
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEEHHHHHHHHHHH
GLVNNNNKPIRVHVTSVDKAAPFYKEKQMQQEKTAYFTMHYGSVNPEMTFSNFLVTPEND
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCEECCEEECCCCC
LPFRVLQEFTKSPDENGGVTFNPIYLFGPEGSGKTHLMQSAISVLRESGGKILYVSSDLF
CCHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHH
TEHLVSAIRSGEMQKFRSFYRNIDALFIEDIEVFSGKSATQEEFFHTFNSLHSEGKLIVV
HHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEE
SSSYAPVDLVAVEDRLISRFEWGVAIPIHPLVQEGLRSFLMRQVERLSIRIQETALDFLI
ECCCCCEEEEEHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALSSNVKTLLHALNLLAKRVMYKKLSHQLLYEDDVKTLLKDVLEAAGSVRLTPLKIIRN
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHH
VAQYYGVSQESILGRSQSREYVLPRQVAMYFCRQKLSLSYVRIGDVFSRDHSTVISSIRL
HHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHHCHHHHHHHHHHH
IEQKIEENSHDIHMAIQDISKNLNSLHKSLEFFPSEEMII
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362