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The map label for this gene is fabD

Identifier: 15618217

GI number: 15618217

Start: 334771

End: 335697

Strand: Reverse

Name: fabD

Synonym: CPn0297

Alternate gene names: 15618217

Gene position: 335697-334771 (Counterclockwise)

Preceding gene: 15618218

Following gene: 15618216

Centisome position: 27.29

GC content: 39.48

Gene sequence:

>927_bases
ATGAAAAAACGTTATGCTTTTTTGTTCCCAGGACAAGGGAGCCAATATGTAGGTATGGGACAAGACCTATATATGGAGTA
TCCTGAGGTTAGAGAGCTTTTTGATTTTGCTAATGAAAGGTTAGGATTTTCTCTGACTTCAATTATGTTTGAAGGTCCTG
AGGATCTTTTGATGGAAACAGTACATAGTCAGCTAGCTATTTATCTTCATAGCATGGCTGTGGTAAAGGTTCTATCTCAG
CGTTCTTCTATTCAGCCTTCTTTAGTCTCTGGATTAAGTTTAGGGGAGTATACTGCTTTAGTTGCTTCCGATAGAATCTC
CGTGCTCGACGGCCTTGAGCTTGTTAGAAAGCGTGGTCAGTTAATGAATGAAGCTTGTAATCAGAGCCCAGGGGCTATGG
CGGCTTTATTAGGGCTTCCCTCTGAAGTTATAGAGGAAAATATAACAAGTCTTGGTCAAGGAATTTGGATTGCTAATTAT
AATGCACCCAAACAGCTTGTAGTGGCTGGAATAGCAGAAAAAGTAGACCAAGCGATTGAGTTATTTCGTGATTTAGGATG
TAAAAAAGCAGTTCGTTTAAAGGTGTCTGGAGCATTTCATACTCCTTTAATGCAAGTTGCTCAAGATGGCTTAGCTCCAG
ACATTTATGCTTTATGCATGAAAGATTCTAGCCTTCCCTTAGTGTCACACGTGGTAGGAAAATCTTTAGTAAATACTGAA
GAAATGCGAGAGTGTTTAGCTCGGCAAATGACATCACCTACGTTATGGTATCAGAGTTGTTACCATATCGAATCAGAGGT
GGATGAGTTTTTAGAATTAGGTCCAGGAAAAGTTTTGGCTGGTTTAAATCGCTCTATAGGGATTTCTAAACCGATTACAA
GTCTTGGTACTTTTGCTCAGATTGAAAAATTCCTATCAGAGGTATGA

Upstream 100 bases:

>100_bases
TCCATTAAGCTTGATGATTATTTACTTTTAGTTGCCTTTGGGGGCGGTTTGTCTTGGGGCGCAGTAGTTTTAAAGCAGGT
CTAATAAGGACGATAATTTC

Downstream 100 bases:

>100_bases
TTTGTATGGATATAACATTAGTAGGCAAAAAAGTTATAGTAACTGGAGGATCTCGAGGAATTGGACTCGGGATAGTTAAG
CTTTTTCTTGAGAACGGAGC

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKKRYAFLFPGQGSQYVGMGQDLYMEYPEVRELFDFANERLGFSLTSIMFEGPEDLLMETVHSQLAIYLHSMAVVKVLSQ
RSSIQPSLVSGLSLGEYTALVASDRISVLDGLELVRKRGQLMNEACNQSPGAMAALLGLPSEVIEENITSLGQGIWIANY
NAPKQLVVAGIAEKVDQAIELFRDLGCKKAVRLKVSGAFHTPLMQVAQDGLAPDIYALCMKDSSLPLVSHVVGKSLVNTE
EMRECLARQMTSPTLWYQSCYHIESEVDEFLELGPGKVLAGLNRSIGISKPITSLGTFAQIEKFLSEV

Sequences:

>Translated_308_residues
MKKRYAFLFPGQGSQYVGMGQDLYMEYPEVRELFDFANERLGFSLTSIMFEGPEDLLMETVHSQLAIYLHSMAVVKVLSQ
RSSIQPSLVSGLSLGEYTALVASDRISVLDGLELVRKRGQLMNEACNQSPGAMAALLGLPSEVIEENITSLGQGIWIANY
NAPKQLVVAGIAEKVDQAIELFRDLGCKKAVRLKVSGAFHTPLMQVAQDGLAPDIYALCMKDSSLPLVSHVVGKSLVNTE
EMRECLARQMTSPTLWYQSCYHIESEVDEFLELGPGKVLAGLNRSIGISKPITSLGTFAQIEKFLSEV
>Mature_308_residues
MKKRYAFLFPGQGSQYVGMGQDLYMEYPEVRELFDFANERLGFSLTSIMFEGPEDLLMETVHSQLAIYLHSMAVVKVLSQ
RSSIQPSLVSGLSLGEYTALVASDRISVLDGLELVRKRGQLMNEACNQSPGAMAALLGLPSEVIEENITSLGQGIWIANY
NAPKQLVVAGIAEKVDQAIELFRDLGCKKAVRLKVSGAFHTPLMQVAQDGLAPDIYALCMKDSSLPLVSHVVGKSLVNTE
EMRECLARQMTSPTLWYQSCYHIESEVDEFLELGPGKVLAGLNRSIGISKPITSLGTFAQIEKFLSEV

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=303, Percent_Identity=32.3432343234323, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI27477045, Length=111, Percent_Identity=42.3423423423423, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787334, Length=286, Percent_Identity=37.4125874125874, Blast_Score=178, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI71984332, Length=301, Percent_Identity=28.9036544850498, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=299, Percent_Identity=26.7558528428094, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24665753, Length=316, Percent_Identity=34.1772151898734, Blast_Score=155, Evalue=2e-38,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33846; Mature: 33846

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRYAFLFPGQGSQYVGMGQDLYMEYPEVRELFDFANERLGFSLTSIMFEGPEDLLMET
CCCCEEEEECCCCCCEECCCHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHH
VHSQLAIYLHSMAVVKVLSQRSSIQPSLVSGLSLGEYTALVASDRISVLDGLELVRKRGQ
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHH
LMNEACNQSPGAMAALLGLPSEVIEENITSLGQGIWIANYNAPKQLVVAGIAEKVDQAIE
HHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHH
LFRDLGCKKAVRLKVSGAFHTPLMQVAQDGLAPDIYALCMKDSSLPLVSHVVGKSLVNTE
HHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCHH
EMRECLARQMTSPTLWYQSCYHIESEVDEFLELGPGKVLAGLNRSIGISKPITSLGTFAQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHH
IEKFLSEV
HHHHHHCC
>Mature Secondary Structure
MKKRYAFLFPGQGSQYVGMGQDLYMEYPEVRELFDFANERLGFSLTSIMFEGPEDLLMET
CCCCEEEEECCCCCCEECCCHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHH
VHSQLAIYLHSMAVVKVLSQRSSIQPSLVSGLSLGEYTALVASDRISVLDGLELVRKRGQ
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHH
LMNEACNQSPGAMAALLGLPSEVIEENITSLGQGIWIANYNAPKQLVVAGIAEKVDQAIE
HHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHH
LFRDLGCKKAVRLKVSGAFHTPLMQVAQDGLAPDIYALCMKDSSLPLVSHVVGKSLVNTE
HHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCHH
EMRECLARQMTSPTLWYQSCYHIESEVDEFLELGPGKVLAGLNRSIGISKPITSLGTFAQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHH
IEKFLSEV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]