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The map label for this gene is dnaX_1

Identifier: 15617964

GI number: 15617964

Start: 54315

End: 55643

Strand: Reverse

Name: dnaX_1

Synonym: CPn0040

Alternate gene names: 15617964

Gene position: 55643-54315 (Counterclockwise)

Preceding gene: 15617973

Following gene: 15617963

Centisome position: 4.52

GC content: 40.71

Gene sequence:

>1329_bases
ATGACTCTACAACCCTACCAAGCATCCTCTAGAAAGTACCGTCCACAAATCTTTCGAGAAATTCTAGGTCAGAGCTCTGT
TGTCGCTGTATTAAAAAATGCCTTGGTCTTCAACCGAGCCGCCCACGCCTATCTATTTTCTGGAATTCGTGGTACAGGGA
AAACCACACTAGCTCGCATTTTAGCAAAAGCTCTGAACTGCGTGCATCTTAGCGAGGATGGCGAGCCCTGCAACCAGTGT
TTTTCTTGTAAAGAGATTGCTTCAGGATCCTCTTTAGACGTTTTAGAAATTGACGGAGCCTCCCACCGTGGTATCGAAGA
TATCCGTCAAATTAATGAAACTGTATTATTCACTCCTGTAAAAGCAAAGTTTAAAATTTATATCATAGATGAAGTTCATA
TGCTCACTAAGGAAGCCTTCAATGCTTTATTGAAGACTTTAGAAGAGCCTCCACAACATGTAAAATTTTTCTTTGCAACT
ACAGAAATCCATAAAATTCCCGGAACTATTTTAAGTCGTTGTCAAAAAATGCATCTTCAAAGGATTCCTGAAAAAACGAT
CCTGGAGAAGCTATCGCTTATGGCTCAAGATGACCATATTGAGGCGTCGCAAGAAGCATTGGCGCCGATCGCCCGTGCAG
CACAAGGAAGCTTGCGTGATGCAGAATCTCTTTATGACTACGTAATATCTTTATTTCCTAAATCTCTCTCTCCCGACACG
GTTGCCCAAGCTTTAGGCTTTGCTTCCCAAGATTCTCTCCGGACTTTAGACAATGCGATTCTTCAAAGGGACTATGCGAC
AGCCTTAGGGATCGTAACGGACTTCTTAAATTCTGGGGTAGCACCTGTCACATTTCTCCATGACCTTACATTATTTTATC
GTAATCTTCTTCTTACGAATTCTACAACAAGCAAGTTCAGCTCTCAGTATAAGACGGAGCAGCTTCTAGAAATCATAGAT
TTCCTTGGAGAATCTGCTAAGCACCTACAAAATACCATCTTCGAACAGACATTTTTAGAAACCGTCATCATTCATATCAT
TCGCATTTATCAAAGGCCTGTTTTATCAGAGTTGATCTCTTCTATTAAGAGTCGGCAGTTTGAAGGGCTTCGCAATATTA
AGGAGCCCACCTTGACGCAGCAAGTATCAGCTCCTCAACCTCAGCCCACCTACAAAGAACAGAGTTTTTTAGAGAAAAAA
AATCAACCTGCTGCGGAAGGTAAAATTATATCTGTAGAAGTTAAAAGCTCAGCTTCAATAAAATCTGCAGCTGTAGACAC
ATTATTACAGTTTGCTGTTGTAGAATTTTCAGGAATTTTAAGACAATAA

Upstream 100 bases:

>100_bases
CTGCGAAAAGAATTTTCTTATGAAAATCAGAAAAGGTCTTCAAGAAAAAATCTCTTAAATGAGAAAATGAGCTTTCTATA
CACATTCTCTTGGTTATACA

Downstream 100 bases:

>100_bases
GCAAGAACCTCTTAGAAAATTTCATGAGAGGAAAGATCAATATTTCACCTAAGGATAGATAAGCATGGGCAGCGGATACG
CTAAGAAAAAAAAAGAAGCT

Product: DNA polymerase III subunits gamma/tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTLQPYQASSRKYRPQIFREILGQSSVVAVLKNALVFNRAAHAYLFSGIRGTGKTTLARILAKALNCVHLSEDGEPCNQC
FSCKEIASGSSLDVLEIDGASHRGIEDIRQINETVLFTPVKAKFKIYIIDEVHMLTKEAFNALLKTLEEPPQHVKFFFAT
TEIHKIPGTILSRCQKMHLQRIPEKTILEKLSLMAQDDHIEASQEALAPIARAAQGSLRDAESLYDYVISLFPKSLSPDT
VAQALGFASQDSLRTLDNAILQRDYATALGIVTDFLNSGVAPVTFLHDLTLFYRNLLLTNSTTSKFSSQYKTEQLLEIID
FLGESAKHLQNTIFEQTFLETVIIHIIRIYQRPVLSELISSIKSRQFEGLRNIKEPTLTQQVSAPQPQPTYKEQSFLEKK
NQPAAEGKIISVEVKSSASIKSAAVDTLLQFAVVEFSGILRQ

Sequences:

>Translated_442_residues
MTLQPYQASSRKYRPQIFREILGQSSVVAVLKNALVFNRAAHAYLFSGIRGTGKTTLARILAKALNCVHLSEDGEPCNQC
FSCKEIASGSSLDVLEIDGASHRGIEDIRQINETVLFTPVKAKFKIYIIDEVHMLTKEAFNALLKTLEEPPQHVKFFFAT
TEIHKIPGTILSRCQKMHLQRIPEKTILEKLSLMAQDDHIEASQEALAPIARAAQGSLRDAESLYDYVISLFPKSLSPDT
VAQALGFASQDSLRTLDNAILQRDYATALGIVTDFLNSGVAPVTFLHDLTLFYRNLLLTNSTTSKFSSQYKTEQLLEIID
FLGESAKHLQNTIFEQTFLETVIIHIIRIYQRPVLSELISSIKSRQFEGLRNIKEPTLTQQVSAPQPQPTYKEQSFLEKK
NQPAAEGKIISVEVKSSASIKSAAVDTLLQFAVVEFSGILRQ
>Mature_441_residues
TLQPYQASSRKYRPQIFREILGQSSVVAVLKNALVFNRAAHAYLFSGIRGTGKTTLARILAKALNCVHLSEDGEPCNQCF
SCKEIASGSSLDVLEIDGASHRGIEDIRQINETVLFTPVKAKFKIYIIDEVHMLTKEAFNALLKTLEEPPQHVKFFFATT
EIHKIPGTILSRCQKMHLQRIPEKTILEKLSLMAQDDHIEASQEALAPIARAAQGSLRDAESLYDYVISLFPKSLSPDTV
AQALGFASQDSLRTLDNAILQRDYATALGIVTDFLNSGVAPVTFLHDLTLFYRNLLLTNSTTSKFSSQYKTEQLLEIIDF
LGESAKHLQNTIFEQTFLETVIIHIIRIYQRPVLSELISSIKSRQFEGLRNIKEPTLTQQVSAPQPQPTYKEQSFLEKKN
QPAAEGKIISVEVKSSASIKSAAVDTLLQFAVVEFSGILRQ

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=284, Percent_Identity=24.2957746478873, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI194306571, Length=284, Percent_Identity=24.2957746478873, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI194306567, Length=284, Percent_Identity=24.2957746478873, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4506491, Length=330, Percent_Identity=25.4545454545455, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI31881687, Length=330, Percent_Identity=25.4545454545455, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI31563534, Length=217, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1786676, Length=293, Percent_Identity=43.0034129692833, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI1787341, Length=166, Percent_Identity=30.7228915662651, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71986063, Length=346, Percent_Identity=24.5664739884393, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17554730, Length=290, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17541988, Length=215, Percent_Identity=26.9767441860465, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324039, Length=263, Percent_Identity=24.3346007604563, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324478, Length=215, Percent_Identity=26.5116279069767, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322528, Length=329, Percent_Identity=22.4924012158055, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17647857, Length=215, Percent_Identity=28.8372093023256, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859927, Length=220, Percent_Identity=26.3636363636364, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19921076, Length=252, Percent_Identity=22.6190476190476, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 49346; Mature: 49215

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQPYQASSRKYRPQIFREILGQSSVVAVLKNALVFNRAAHAYLFSGIRGTGKTTLARI
CCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LAKALNCVHLSEDGEPCNQCFSCKEIASGSSLDVLEIDGASHRGIEDIRQINETVLFTPV
HHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHEEEEEC
KAKFKIYIIDEVHMLTKEAFNALLKTLEEPPQHVKFFFATTEIHKIPGTILSRCQKMHLQ
CCEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHEEHHHHHHHHHCCHHHHHHHHHHHHH
RIPEKTILEKLSLMAQDDHIEASQEALAPIARAAQGSLRDAESLYDYVISLFPKSLSPDT
HCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHH
VAQALGFASQDSLRTLDNAILQRDYATALGIVTDFLNSGVAPVTFLHDLTLFYRNLLLTN
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
STTSKFSSQYKTEQLLEIIDFLGESAKHLQNTIFEQTFLETVIIHIIRIYQRPVLSELIS
CCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIKSRQFEGLRNIKEPTLTQQVSAPQPQPTYKEQSFLEKKNQPAAEGKIISVEVKSSASI
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCHH
KSAAVDTLLQFAVVEFSGILRQ
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLQPYQASSRKYRPQIFREILGQSSVVAVLKNALVFNRAAHAYLFSGIRGTGKTTLARI
CCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LAKALNCVHLSEDGEPCNQCFSCKEIASGSSLDVLEIDGASHRGIEDIRQINETVLFTPV
HHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHEEEEEC
KAKFKIYIIDEVHMLTKEAFNALLKTLEEPPQHVKFFFATTEIHKIPGTILSRCQKMHLQ
CCEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHEEHHHHHHHHHCCHHHHHHHHHHHHH
RIPEKTILEKLSLMAQDDHIEASQEALAPIARAAQGSLRDAESLYDYVISLFPKSLSPDT
HCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHH
VAQALGFASQDSLRTLDNAILQRDYATALGIVTDFLNSGVAPVTFLHDLTLFYRNLLLTN
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
STTSKFSSQYKTEQLLEIIDFLGESAKHLQNTIFEQTFLETVIIHIIRIYQRPVLSELIS
CCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIKSRQFEGLRNIKEPTLTQQVSAPQPQPTYKEQSFLEKKNQPAAEGKIISVEVKSSASI
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCHH
KSAAVDTLLQFAVVEFSGILRQ
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]