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The map label for this gene is atoC [H]

Identifier: 15607134

GI number: 15607134

Start: 56372

End: 57964

Strand: Direct

Name: atoC [H]

Synonym: aq_091m

Alternate gene names: 15607134

Gene position: 56372-57964 (Clockwise)

Preceding gene: 15605685

Following gene: 15605688

Centisome position: 3.63

GC content: 44.95

Gene sequence:

>1593_bases
ATGTTTAAATTTATAAACAAGGTGGATTTTAAAACATTTGACGAAATTTTTGACGGTGTTCTCGTAATAGATAAAAACAG
GAGGATAGTTTTTGCTAACAAAAAGGCAAAAGAAATACTGGGGGAGGTAAAGGAGGGAGAGTCCTGCAGGGGGCTTTTTT
CCATTTGTGAACACTGCCCTATGGAACTTGTTGAGGACTCAGAGCAAGGAGTTCAGGTTTACGACGTCCTGACGAAAAGG
AAAAATCACGTGTGCCTCAGTATGAGTCCCCTCTTTGAGGGAGGGGAATTTACAGGAGTCCTTGAAGTTTTCAGGGATGT
GAGCAAGGTAATCCACTACATGGAAGAGGTTAAAAGACAAAAGGAGTTTGTAGAAGTCGTACTTGACTCTATCGTGGAGG
CTGTTCTCGTTCTGGACGAAAAAGGGAACGTTATAAACCACAACGGGAACGCAAGCAAAGTTCTTTGTTCCAGGTTTGAA
AGCATCACAGGAAAAAATCTGAAGGAAATAACTTCTCTGAGTCTGGAAGACCTCCCGCCGGAAGGAGAAAGGGCGGACAT
TTACATAGAAACTCCCTGCGGTAGGCAAAAAGCCTCCGTTCTCCTCTCAAAACTGAAGCAGGGAAAGGGCTGGGTTCTTT
CTCTATACATAGTTCCCGAGATATTCGCAGGTGAGGGAAACAAGTTAAAAATCGTTACAAAGAGTCCAAAGTTTCTGAAG
GTTCTGGAAAAGGTAAAAACGATTTCCGAGATGAATGTAAACGTTTTGATCACTGGAGAGACGGGAACGGGAAAGAGCCT
GCTCGCCAGATATATACACTACCTCTCTCCCAGGAGGGACAAGCCCTTCGTGAAGATAAACTGCGGTGCTATTCCTGAAA
ACTTACTTGAGGCGTAGCTCTTTGGCTACAACAAGGGAGCTTTTACAGGAGCAATTGCGAGTAAACCCGGAAAGGTAGAA
ATGGCAAACGGCGGAACACTTTTTCTGGATGAGATAGGAGAACTTCCGCTACACCTTCAGGTAAAGCTCCTCGGATTGAT
TCAGGACAAGGAGTTTGAAAGGATAGGAGATCTAAAACCGAGAAAGGCGGACGTTAGGATTATCGCGGCTACTAATAAAA
ACCTCAAAAAACTGGTAGAAGAAGGGAAATTCAGGGAGGACCTTTATTACAGGTTGAACGTCGTGAACGTGGAATTACCA
CCACTCAGGGAGAGGAAGGAGGATATACCTCACCTTGTGAGTTACTTCCTCGAGAAATTTTCAAAGATCCACGGGAAGAA
GGTTAAGGGAGTATCTCCCGAAGCCATGAAACTGCTCTTAGAGTACGATTATCCGGGAAACGTGAGGGAACTTGAAAACG
CAATTGAACACGCTGTTGTGGTCTCAAGCACGAGTTTAATAGGACCCGACGACCTGCCTGAAGAGATAAGAATCGGAAGC
AAAGTTAAGAAGAAGTTCAGGGAGAACGAGGAACTGGAGAAGATAAAAGAAGCCTTGGAAAGGGCTGGGGGAAACAAAAG
CCTTGCGGCAAAGCTCTTGGGTATCCACAGGACCACTCTGTGGAGGAAGTTAAAGGAATACGGGCTTGCTTAG

Upstream 100 bases:

>100_bases
AAGAGGTTAAAGTTTAAGGGTTCTATGATTACAGCTATGAAGTACATGGGAGCCTTTGAAGAGAGCTTAAAGATGATGGG
CAGAGTTCCGACGGTCTGGG

Downstream 100 bases:

>100_bases
ACACTGCACGCCTCGCATTCCTCAATATCCATAGCCGAACGGCTCCTGAGGTAGTATATCGTCTTTAGTCCGAGTTCCCA
GGCAAGTTCGTAGAGTCTGG

Product: ATPase AAA

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MFKFINKVDFKTFDEIFDGVLVIDKNRRIVFANKKAKEILGEVKEGESCRGLFSICEHCPMELVEDSEQGVQVYDVLTKR
KNHVCLSMSPLFEGGEFTGVLEVFRDVSKVIHYMEEVKRQKEFVEVVLDSIVEAVLVLDEKGNVINHNGNASKVLCSRFE
SITGKNLKEITSLSLEDLPPEGERADIYIETPCGRQKASVLLSKLKQGKGWVLSLYIVPEIFAGEGNKLKIVTKSPKFLK
VLEKVKTISEMNVNVLITGETGTGKSLLARYIHYLSPRRDKPFVKINCGAIPENLLEAXLFGYNKGAFTGAIASKPGKVE
MANGGTLFLDEIGELPLHLQVKLLGLIQDKEFERIGDLKPRKADVRIIAATNKNLKKLVEEGKFREDLYYRLNVVNVELP
PLRERKEDIPHLVSYFLEKFSKIHGKKVKGVSPEAMKLLLEYDYPGNVRELENAIEHAVVVSSTSLIGPDDLPEEIRIGS
KVKKKFRENEELEKIKEALERAGGNKSLAAKLLGIHRTTLWRKLKEYGLA

Sequences:

>Translated_530_residues
MFKFINKVDFKTFDEIFDGVLVIDKNRRIVFANKKAKEILGEVKEGESCRGLFSICEHCPMELVEDSEQGVQVYDVLTKR
KNHVCLSMSPLFEGGEFTGVLEVFRDVSKVIHYMEEVKRQKEFVEVVLDSIVEAVLVLDEKGNVINHNGNASKVLCSRFE
SITGKNLKEITSLSLEDLPPEGERADIYIETPCGRQKASVLLSKLKQGKGWVLSLYIVPEIFAGEGNKLKIVTKSPKFLK
VLEKVKTISEMNVNVLITGETGTGKSLLARYIHYLSPRRDKPFVKINCGAIPENLLEA*LFGYNKGAFTGAIASKPGKVE
MANGGTLFLDEIGELPLHLQVKLLGLIQDKEFERIGDLKPRKADVRIIAATNKNLKKLVEEGKFREDLYYRLNVVNVELP
PLRERKEDIPHLVSYFLEKFSKIHGKKVKGVSPEAMKLLLEYDYPGNVRELENAIEHAVVVSSTSLIGPDDLPEEIRIGS
KVKKKFRENEELEKIKEALERAGGNKSLAAKLLGIHRTTLWRKLKEYGLA
>Mature_530_residues
MFKFINKVDFKTFDEIFDGVLVIDKNRRIVFANKKAKEILGEVKEGESCRGLFSICEHCPMELVEDSEQGVQVYDVLTKR
KNHVCLSMSPLFEGGEFTGVLEVFRDVSKVIHYMEEVKRQKEFVEVVLDSIVEAVLVLDEKGNVINHNGNASKVLCSRFE
SITGKNLKEITSLSLEDLPPEGERADIYIETPCGRQKASVLLSKLKQGKGWVLSLYIVPEIFAGEGNKLKIVTKSPKFLK
VLEKVKTISEMNVNVLITGETGTGKSLLARYIHYLSPRRDKPFVKINCGAIPENLLEA*LFGYNKGAFTGAIASKPGKVE
MANGGTLFLDEIGELPLHLQVKLLGLIQDKEFERIGDLKPRKADVRIIAATNKNLKKLVEEGKFREDLYYRLNVVNVELP
PLRERKEDIPHLVSYFLEKFSKIHGKKVKGVSPEAMKLLLEYDYPGNVRELENAIEHAVVVSSTSLIGPDDLPEEIRIGS
KVKKKFRENEELEKIKEALERAGGNKSLAAKLLGIHRTTLWRKLKEYGLA

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=312, Percent_Identity=48.7179487179487, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1790437, Length=314, Percent_Identity=46.8152866242038, Blast_Score=274, Evalue=8e-75,
Organism=Escherichia coli, GI87082117, Length=320, Percent_Identity=44.6875, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI1788905, Length=303, Percent_Identity=43.8943894389439, Blast_Score=258, Evalue=8e-70,
Organism=Escherichia coli, GI1790299, Length=334, Percent_Identity=41.9161676646707, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1789233, Length=432, Percent_Identity=38.8888888888889, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1789087, Length=307, Percent_Identity=44.299674267101, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI87082152, Length=319, Percent_Identity=41.692789968652, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1786524, Length=315, Percent_Identity=41.9047619047619, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI87081872, Length=307, Percent_Identity=40.0651465798046, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1787583, Length=312, Percent_Identity=39.4230769230769, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1789828, Length=259, Percent_Identity=37.4517374517375, Blast_Score=165, Evalue=8e-42,
Organism=Escherichia coli, GI87081858, Length=461, Percent_Identity=28.1995661605206, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 59564; Mature: 59564

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFINKVDFKTFDEIFDGVLVIDKNRRIVFANKKAKEILGEVKEGESCRGLFSICEHCP
CCCCHHHCCHHHHHHHHCCEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCC
MELVEDSEQGVQVYDVLTKRKNHVCLSMSPLFEGGEFTGVLEVFRDVSKVIHYMEEVKRQ
HHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KEFVEVVLDSIVEAVLVLDEKGNVINHNGNASKVLCSRFESITGKNLKEITSLSLEDLPP
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHCCCCHHHHHHCHHHCCCC
EGERADIYIETPCGRQKASVLLSKLKQGKGWVLSLYIVPEIFAGEGNKLKIVTKSPKFLK
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEEEHCCCCCCEEEEEECCCHHHH
VLEKVKTISEMNVNVLITGETGTGKSLLARYIHYLSPRRDKPFVKINCGAIPENLLEALF
HHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHH
GYNKGAFTGAIASKPGKVEMANGGTLFLDEIGELPLHLQVKLLGLIQDKEFERIGDLKPR
CCCCCCEEEHHCCCCCEEEECCCCEEEEEHHCCCCEEEEEEEHHHHCCCHHHHHCCCCCC
KADVRIIAATNKNLKKLVEEGKFREDLYYRLNVVNVELPPLRERKEDIPHLVSYFLEKFS
CCCEEEEEECCHHHHHHHHCCCCHHCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
KIHGKKVKGVSPEAMKLLLEYDYPGNVRELENAIEHAVVVSSTSLIGPDDLPEEIRIGSK
HHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCHHHHHCCHH
VKKKFRENEELEKIKEALERAGGNKSLAAKLLGIHRTTLWRKLKEYGLA
HHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKFINKVDFKTFDEIFDGVLVIDKNRRIVFANKKAKEILGEVKEGESCRGLFSICEHCP
CCCCHHHCCHHHHHHHHCCEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCC
MELVEDSEQGVQVYDVLTKRKNHVCLSMSPLFEGGEFTGVLEVFRDVSKVIHYMEEVKRQ
HHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KEFVEVVLDSIVEAVLVLDEKGNVINHNGNASKVLCSRFESITGKNLKEITSLSLEDLPP
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHCCCCHHHHHHCHHHCCCC
EGERADIYIETPCGRQKASVLLSKLKQGKGWVLSLYIVPEIFAGEGNKLKIVTKSPKFLK
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEEEHCCCCCCEEEEEECCCHHHH
VLEKVKTISEMNVNVLITGETGTGKSLLARYIHYLSPRRDKPFVKINCGAIPENLLEALF
HHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHH
GYNKGAFTGAIASKPGKVEMANGGTLFLDEIGELPLHLQVKLLGLIQDKEFERIGDLKPR
CCCCCCEEEHHCCCCCEEEECCCCEEEEEHHCCCCEEEEEEEHHHHCCCHHHHHCCCCCC
KADVRIIAATNKNLKKLVEEGKFREDLYYRLNVVNVELPPLRERKEDIPHLVSYFLEKFS
CCCEEEEEECCHHHHHHHHCCCCHHCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
KIHGKKVKGVSPEAMKLLLEYDYPGNVRELENAIEHAVVVSSTSLIGPDDLPEEIRIGSK
HHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCHHHHHCCHH
VKKKFRENEELEKIKEALERAGGNKSLAAKLLGIHRTTLWRKLKEYGLA
HHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]