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The map label for this gene is argB [H]

Identifier: 15607035

GI number: 15607035

Start: 1455909

End: 1456727

Strand: Direct

Name: argB [H]

Synonym: aq_2068

Alternate gene names: 15607035

Gene position: 1455909-1456727 (Clockwise)

Preceding gene: 15607034

Following gene: 15607036

Centisome position: 93.85

GC content: 46.15

Gene sequence:

>819_bases
GTGATAAAGTACGGCGGTTCCGCAATGCACGACGAGGAACTCAGAGAGTCCTTTGCTAGAGACGTGGTTCTTTTAAAGTA
CGTGGGAATAAACCCGGTAATCGTTCACGGAGGGGGACCACAGATAAGCAAAACACTGGAGAAATTCGGTATAAAACCCA
AATTTGTAGGGGGAATGAGGAAGACTGACGAGGAGACAATGCACGTAGTTGAGATGGTGCTTTCAGGAGACATAAACAAG
GACATAGTAGCCCTTATAAACAGATACAGTGGGGAAAAGATTTACGCGGTCGGACTGTCGGGCAGGGACGGAAGACTCTT
GAAGGCTAAAAAGTTAGACAAAGAGAGGTATTTCTCCGAACTCGGGCTTCCCGTTCCTGAGGAAGATATCGGGTTTGTAG
GGGAAATAGTGGACGTAAATGAAGAGCTTATATTTACTCTGCTTTCCCACAACTTCATCCCAGTAATAGCTCCCGTGGGA
GTAGGGGAAGAAGGTGAGGCTTACAACGTAAACGCGGACCTCGCAGCCTCGGAAATAGCGGGAGAGATTAAAGCGGAAAA
ACTCATATACCTTACCGACACAAAAGGTGTCCTTGACGAAAAGGGAGAGTTAATTTCTTCCCTTTCAAAGGATAAGGCGG
AAGAATTAATTAAGAAGGGAGTAATTAGGGAGGGAATGATTCCAAAGGTTCGTTCCGCCCTTAGGGCACTTGAGAAGGGT
GTTAAAAAGGTTCACATAATAGACGGGAGGGTGAAGCACTCTATACTCCTTGAGGTTTTCACAAAGGAGGGGGTGGGAAC
TGAGATTACTCTGGAATAA

Upstream 100 bases:

>100_bases
GCTACCGTTGAAGAAAAGAAGGAATGAATGAGTTAATAGAAAAGGCTAAGTTCTTCAGGAAGCCCTGCCTTACATACGGG
AATTTCACGGAAAGGTTTTC

Downstream 100 bases:

>100_bases
ATTAAAAAATTTATGGAGAAGTTCGTAGACAGAGTAAAAATCTTCGTGAAAGGGGGAAAGGGCGGAGACGGAGCAGTAGC
CTTTTTGAGGGAAAAGTACA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MIKYGGSAMHDEELRESFARDVVLLKYVGINPVIVHGGGPQISKTLEKFGIKPKFVGGMRKTDEETMHVVEMVLSGDINK
DIVALINRYSGEKIYAVGLSGRDGRLLKAKKLDKERYFSELGLPVPEEDIGFVGEIVDVNEELIFTLLSHNFIPVIAPVG
VGEEGEAYNVNADLAASEIAGEIKAEKLIYLTDTKGVLDEKGELISSLSKDKAEELIKKGVIREGMIPKVRSALRALEKG
VKKVHIIDGRVKHSILLEVFTKEGVGTEITLE

Sequences:

>Translated_272_residues
MIKYGGSAMHDEELRESFARDVVLLKYVGINPVIVHGGGPQISKTLEKFGIKPKFVGGMRKTDEETMHVVEMVLSGDINK
DIVALINRYSGEKIYAVGLSGRDGRLLKAKKLDKERYFSELGLPVPEEDIGFVGEIVDVNEELIFTLLSHNFIPVIAPVG
VGEEGEAYNVNADLAASEIAGEIKAEKLIYLTDTKGVLDEKGELISSLSKDKAEELIKKGVIREGMIPKVRSALRALEKG
VKKVHIIDGRVKHSILLEVFTKEGVGTEITLE
>Mature_272_residues
MIKYGGSAMHDEELRESFARDVVLLKYVGINPVIVHGGGPQISKTLEKFGIKPKFVGGMRKTDEETMHVVEMVLSGDINK
DIVALINRYSGEKIYAVGLSGRDGRLLKAKKLDKERYFSELGLPVPEEDIGFVGEIVDVNEELIFTLLSHNFIPVIAPVG
VGEEGEAYNVNADLAASEIAGEIKAEKLIYLTDTKGVLDEKGELISSLSKDKAEELIKKGVIREGMIPKVRSALRALEKG
VKKVHIIDGRVKHSILLEVFTKEGVGTEITLE

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI145693208, Length=270, Percent_Identity=33.7037037037037, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789181, Length=277, Percent_Identity=27.0758122743682, Blast_Score=108, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320913, Length=273, Percent_Identity=30.03663003663, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 29855; Mature: 29855

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKYGGSAMHDEELRESFARDVVLLKYVGINPVIVHGGGPQISKTLEKFGIKPKFVGGMR
CCCCCCCCCCHHHHHHHHHHHEEEEEEECCCEEEEECCCCHHHHHHHHHCCCCHHCCCCC
KTDEETMHVVEMVLSGDINKDIVALINRYSGEKIYAVGLSGRDGRLLKAKKLDKERYFSE
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHH
LGLPVPEEDIGFVGEIVDVNEELIFTLLSHNFIPVIAPVGVGEEGEAYNVNADLAASEIA
CCCCCCHHHHCHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCHHHHHHH
GEIKAEKLIYLTDTKGVLDEKGELISSLSKDKAEELIKKGVIREGMIPKVRSALRALEKG
HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
VKKVHIIDGRVKHSILLEVFTKEGVGTEITLE
CCEEEEECCHHHHHHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure
MIKYGGSAMHDEELRESFARDVVLLKYVGINPVIVHGGGPQISKTLEKFGIKPKFVGGMR
CCCCCCCCCCHHHHHHHHHHHEEEEEEECCCEEEEECCCCHHHHHHHHHCCCCHHCCCCC
KTDEETMHVVEMVLSGDINKDIVALINRYSGEKIYAVGLSGRDGRLLKAKKLDKERYFSE
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHH
LGLPVPEEDIGFVGEIVDVNEELIFTLLSHNFIPVIAPVGVGEEGEAYNVNADLAASEIA
CCCCCCHHHHCHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCHHHHHHH
GEIKAEKLIYLTDTKGVLDEKGELISSLSKDKAEELIKKGVIREGMIPKVRSALRALEKG
HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
VKKVHIIDGRVKHSILLEVFTKEGVGTEITLE
CCEEEEECCHHHHHHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]