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The map label for this gene is engA

Identifier: 15606936

GI number: 15606936

Start: 1350037

End: 1351338

Strand: Direct

Name: engA

Synonym: aq_1919

Alternate gene names: 15606936

Gene position: 1350037-1351338 (Clockwise)

Preceding gene: 15606935

Following gene: 15606939

Centisome position: 87.02

GC content: 44.62

Gene sequence:

>1302_bases
ATGAGTAACAGAGTAGTCATTATCGGAAGACCCAATGTGGGAAAGTCCACACTGTTCAACAGGATTATAGGGAAAAGATA
CGCCATAGTTGAAGACTATCCCGGCGTTACGAGGGACAAAATAGAAGCAAAGGCAGAGTGGGCGGGCAAAGAGTTCATAA
TAGTGGACACAGGGGGACTCGTTCCAGAAACGAAGGACGAACTCATCAGAGAAGTTAAAAAAGTTGTGGAACAGGAAATC
CCGAAAGCGGACGTAATACTCTTCGTGGTGGATGGAAAGGAAGGGCTAAATCCTCTGGATCAGGAGATAGCAAAGTACCT
TTACCCTTACGCGGATAAAGTTCTCCTCGTCGTAAACAAGATAGACAACCTGAGGCAGGAGAAAAACGTAGCAGAGTTTT
ACACCCTAGGTTTTGAAAAGATTTTTCCTATATCCGCCCAACACGGAAAAGGGGTTGGAGAGCTTCTGGACGAGGTTGTA
AAGTACCTCAAAGAAGAGAAGGTAGAGACTGTAGAAGAGGGTATAAAGGTAGCCTTTATAGGAAGACCGAACGTGGGGAA
ATCCTCGCTCGTTAATGCAATCCTCAAGGACGAGAGGGTTATAGTTTCGCCCATTGCAGGAACCACTAGGGACGCGATAG
AAATACCCTTCAGGTGGAAGGACAAAAACTTCATTTTGATAGACACTGCCGGTGTGAGGAGACCCTCAAACGTTGAATAC
GGTATAGAGTTTTATTCCGTAGGGAGGAGTTTAAAGGCTATTGACCTTGCGGATGTATGCTGTTTAGTCATAGACGCCTC
GGAAGGTCCTACCCGTCAAGATAAGAGACTCGGAGGACTTATAGAGAGAAGGTATAAGGGTTGTGTCATAGTTGCAAACA
AGATGGACATATCTCCATGGAGTGAAGAAGAGCTTGAAGGGATAATCAGAAAGGAACTCTTCTTTTTAGACTTCGCACCA
ATAGTGTTTACGGTTGCGACGAAGGGAAAGGGAGTTGAGGAACTCCTGAACTGGATAGACGTAGTTTACAAGGATTACAC
AAAACAACACAAGACTTCCTTTGTAAACCGAGCGGTTCACAAAATACTCTCTGAAAAACCGCCTCCTAGGTACAGGGGAA
AGGAGGTAAAGGTTTATTACGCCTTTCAGGAAAGCACGAAACCGCCAACGATTGTTCTCATAACAAACTACCCTGACGCC
TGGAAGGAAAACTACAAACGCTTTTTCATAAAGAAACTCAGAGAGTACCTGAACATCAAGTATGCCCCAATAAAGCTCGT
GATAAAGGGAAGGGAAGATTAA

Upstream 100 bases:

>100_bases
TTAAGTTTGAAGAACTTTCTCGTAAGGAAGAGGAAGTTATAGGACAGTTCATTTTGGAAGAACAGAGAAAGCTACTGAAG
GCTTACAAGGAAGGAGAGGT

Downstream 100 bases:

>100_bases
TTATTGATAACTCCTCACAAGGGAAAGGACTACGAGTTCCCAGCCGTTTGCGAGGACAAAGAGCATTATCTTAAAGGGGA
GGGAGATGAGCTGGGGCGGT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MSNRVVIIGRPNVGKSTLFNRIIGKRYAIVEDYPGVTRDKIEAKAEWAGKEFIIVDTGGLVPETKDELIREVKKVVEQEI
PKADVILFVVDGKEGLNPLDQEIAKYLYPYADKVLLVVNKIDNLRQEKNVAEFYTLGFEKIFPISAQHGKGVGELLDEVV
KYLKEEKVETVEEGIKVAFIGRPNVGKSSLVNAILKDERVIVSPIAGTTRDAIEIPFRWKDKNFILIDTAGVRRPSNVEY
GIEFYSVGRSLKAIDLADVCCLVIDASEGPTRQDKRLGGLIERRYKGCVIVANKMDISPWSEEELEGIIRKELFFLDFAP
IVFTVATKGKGVEELLNWIDVVYKDYTKQHKTSFVNRAVHKILSEKPPPRYRGKEVKVYYAFQESTKPPTIVLITNYPDA
WKENYKRFFIKKLREYLNIKYAPIKLVIKGRED

Sequences:

>Translated_433_residues
MSNRVVIIGRPNVGKSTLFNRIIGKRYAIVEDYPGVTRDKIEAKAEWAGKEFIIVDTGGLVPETKDELIREVKKVVEQEI
PKADVILFVVDGKEGLNPLDQEIAKYLYPYADKVLLVVNKIDNLRQEKNVAEFYTLGFEKIFPISAQHGKGVGELLDEVV
KYLKEEKVETVEEGIKVAFIGRPNVGKSSLVNAILKDERVIVSPIAGTTRDAIEIPFRWKDKNFILIDTAGVRRPSNVEY
GIEFYSVGRSLKAIDLADVCCLVIDASEGPTRQDKRLGGLIERRYKGCVIVANKMDISPWSEEELEGIIRKELFFLDFAP
IVFTVATKGKGVEELLNWIDVVYKDYTKQHKTSFVNRAVHKILSEKPPPRYRGKEVKVYYAFQESTKPPTIVLITNYPDA
WKENYKRFFIKKLREYLNIKYAPIKLVIKGRED
>Mature_432_residues
SNRVVIIGRPNVGKSTLFNRIIGKRYAIVEDYPGVTRDKIEAKAEWAGKEFIIVDTGGLVPETKDELIREVKKVVEQEIP
KADVILFVVDGKEGLNPLDQEIAKYLYPYADKVLLVVNKIDNLRQEKNVAEFYTLGFEKIFPISAQHGKGVGELLDEVVK
YLKEEKVETVEEGIKVAFIGRPNVGKSSLVNAILKDERVIVSPIAGTTRDAIEIPFRWKDKNFILIDTAGVRRPSNVEYG
IEFYSVGRSLKAIDLADVCCLVIDASEGPTRQDKRLGGLIERRYKGCVIVANKMDISPWSEEELEGIIRKELFFLDFAPI
VFTVATKGKGVEELLNWIDVVYKDYTKQHKTSFVNRAVHKILSEKPPPRYRGKEVKVYYAFQESTKPPTIVLITNYPDAW
KENYKRFFIKKLREYLNIKYAPIKLVIKGRED

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=459, Percent_Identity=38.562091503268, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1788919, Length=166, Percent_Identity=33.1325301204819, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI2367268, Length=167, Percent_Identity=34.7305389221557, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=117, Percent_Identity=38.4615384615385, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=226, Percent_Identity=30.9734513274336, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_AQUAE (O67749)

Other databases:

- EMBL:   AE000657
- PIR:   A70465
- RefSeq:   NP_214317.1
- ProteinModelPortal:   O67749
- SMR:   O67749
- GeneID:   1193646
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1919
- NMPDR:   fig|224324.1.peg.1332
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   O67749
- ProtClustDB:   PRK00093
- BioCyc:   AAEO224324:AQ_1919-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49393; Mature: 49262

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRVVIIGRPNVGKSTLFNRIIGKRYAIVEDYPGVTRDKIEAKAEWAGKEFIIVDTGGL
CCCCEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCC
VPETKDELIREVKKVVEQEIPKADVILFVVDGKEGLNPLDQEIAKYLYPYADKVLLVVNK
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEHH
IDNLRQEKNVAEFYTLGFEKIFPISAQHGKGVGELLDEVVKYLKEEKVETVEEGIKVAFI
HHHHHHHCCHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GRPNVGKSSLVNAILKDERVIVSPIAGTTRDAIEIPFRWKDKNFILIDTAGVRRPSNVEY
ECCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEECCEEECCCCEEEEECCCCCCCCCCEE
GIEFYSVGRSLKAIDLADVCCLVIDASEGPTRQDKRLGGLIERRYKGCVIVANKMDISPW
CCHHHHHCCCCCHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCC
SEEELEGIIRKELFFLDFAPIVFTVATKGKGVEELLNWIDVVYKDYTKQHKTSFVNRAVH
CHHHHHHHHHHHHHHHEEHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILSEKPPPRYRGKEVKVYYAFQESTKPPTIVLITNYPDAWKENYKRFFIKKLREYLNIK
HHHCCCCCCCCCCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCE
YAPIKLVIKGRED
EEEEEEEEECCCC
>Mature Secondary Structure 
SNRVVIIGRPNVGKSTLFNRIIGKRYAIVEDYPGVTRDKIEAKAEWAGKEFIIVDTGGL
CCCEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCC
VPETKDELIREVKKVVEQEIPKADVILFVVDGKEGLNPLDQEIAKYLYPYADKVLLVVNK
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEHH
IDNLRQEKNVAEFYTLGFEKIFPISAQHGKGVGELLDEVVKYLKEEKVETVEEGIKVAFI
HHHHHHHCCHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GRPNVGKSSLVNAILKDERVIVSPIAGTTRDAIEIPFRWKDKNFILIDTAGVRRPSNVEY
ECCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEECCEEECCCCEEEEECCCCCCCCCCEE
GIEFYSVGRSLKAIDLADVCCLVIDASEGPTRQDKRLGGLIERRYKGCVIVANKMDISPW
CCHHHHHCCCCCHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCC
SEEELEGIIRKELFFLDFAPIVFTVATKGKGVEELLNWIDVVYKDYTKQHKTSFVNRAVH
CHHHHHHHHHHHHHHHEEHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILSEKPPPRYRGKEVKVYYAFQESTKPPTIVLITNYPDAWKENYKRFFIKKLREYLNIK
HHHCCCCCCCCCCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCE
YAPIKLVIKGRED
EEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320