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The map label for this gene is asd

Identifier: 15606903

GI number: 15606903

Start: 1315363

End: 1316385

Strand: Direct

Name: asd

Synonym: aq_1866

Alternate gene names: 15606903

Gene position: 1315363-1316385 (Clockwise)

Preceding gene: 15606902

Following gene: 15606904

Centisome position: 84.79

GC content: 45.26

Gene sequence:

>1023_bases
ATGGGTTACAGAGTCGCGATAGTTGGAGCTACGGGAGAGGTAGGAAGAACATTTCTGAAGGTCCTTGAAGAGAGGAATTT
TCCCGTTGATGAACTCGTACTCTACGCTTCGGAGCGTTCAGAGGGAAAGGTTCTAACTTTTAAGGGGAAGGAGTACACAG
TAAAGGCTCTTAATAAAGAAAATTCTTTTAAAGGTATAGACATAGCACTTTTTTCCGCAGGAGGTTCCACGAGTAAAGAA
TGGGCTCCCAAGTTTGCAAAAGACGGCGTCGTTGTAATAGATAACTCCTCCGCTTGGAGAATGGACCCCGACGTTCCTCT
TGTTGTTCCCGAGGTAAATCCAGAAGACGTAAAGGACTTTAAGAAGAAGGGAATAATAGCAAATCCAAACTGTTCCACCA
TACAGATGGTTGTGGCTCTAAAACCTATATATGACAAAGCGGGAATTAAGAGGGTAGTAGTTTCTACGTATCAGGCTGTT
TCGGGTGCCGGGGCTAAAGCGATTGAGGACCTCAAAAATCAAACTAAAGCCTGGTGCGAAGGGAAGGAAATGCCAAAAGC
CCAGAAGTTTCCTCACCAAATAGCCTTCAACGCCCTTCCCCACATAGATGTTTTCTTTGAAGACGGCTACACGAAGGAAG
AAAATAAGATGCTCTACGAAACGAGGAAGATAATGCACGACGAGAACATAAAGGTTAGTGCAACCTGCGTAAGGATTCCC
GTTTTCTACGGACATTCGGAAAGCATATCCATGGAAACGGAAAAGGAAATATCTCCTGAAGAGGCTAGGGAAGTGCTGAA
AAACGCTCCGGGGGTAATTGTAATTGACAACCCTCAGAACAACGAGTACCCGATGCCTATAATGGCCGAGGGCAGGGACG
AGGTATTTGTCGGAAGGATAAGAAAAGACAGGGTCTTTGAGCCAGGGCTTTCCATGTGGGTAGTTGCGGACAACATAAGA
AAGGGTGCGGCTACCAACGCTGTTCAAATTGCAGAACTTTTAGTGAAAGAAGGACTAATCTAA

Upstream 100 bases:

>100_bases
CTTGAACTTAAAAAAGAAGGGAAAAACCTAAAACCTGTGGTGCCATATGAAGAAATAGAAGTGATCGTTAAAGTGGGTAA
ATCTTAATAAAATTACTTTT

Downstream 100 bases:

>100_bases
AAGGAGGTATGAGATGGCCGAAGTTCAGCACGTTGATGAAGCTTTTGAGACATTAAAAAACGCTAAAGTCGTTGCCGTTG
TAGGCATTTCTCCAAAGCCC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MGYRVAIVGATGEVGRTFLKVLEERNFPVDELVLYASERSEGKVLTFKGKEYTVKALNKENSFKGIDIALFSAGGSTSKE
WAPKFAKDGVVVIDNSSAWRMDPDVPLVVPEVNPEDVKDFKKKGIIANPNCSTIQMVVALKPIYDKAGIKRVVVSTYQAV
SGAGAKAIEDLKNQTKAWCEGKEMPKAQKFPHQIAFNALPHIDVFFEDGYTKEENKMLYETRKIMHDENIKVSATCVRIP
VFYGHSESISMETEKEISPEEAREVLKNAPGVIVIDNPQNNEYPMPIMAEGRDEVFVGRIRKDRVFEPGLSMWVVADNIR
KGAATNAVQIAELLVKEGLI

Sequences:

>Translated_340_residues
MGYRVAIVGATGEVGRTFLKVLEERNFPVDELVLYASERSEGKVLTFKGKEYTVKALNKENSFKGIDIALFSAGGSTSKE
WAPKFAKDGVVVIDNSSAWRMDPDVPLVVPEVNPEDVKDFKKKGIIANPNCSTIQMVVALKPIYDKAGIKRVVVSTYQAV
SGAGAKAIEDLKNQTKAWCEGKEMPKAQKFPHQIAFNALPHIDVFFEDGYTKEENKMLYETRKIMHDENIKVSATCVRIP
VFYGHSESISMETEKEISPEEAREVLKNAPGVIVIDNPQNNEYPMPIMAEGRDEVFVGRIRKDRVFEPGLSMWVVADNIR
KGAATNAVQIAELLVKEGLI
>Mature_339_residues
GYRVAIVGATGEVGRTFLKVLEERNFPVDELVLYASERSEGKVLTFKGKEYTVKALNKENSFKGIDIALFSAGGSTSKEW
APKFAKDGVVVIDNSSAWRMDPDVPLVVPEVNPEDVKDFKKKGIIANPNCSTIQMVVALKPIYDKAGIKRVVVSTYQAVS
GAGAKAIEDLKNQTKAWCEGKEMPKAQKFPHQIAFNALPHIDVFFEDGYTKEENKMLYETRKIMHDENIKVSATCVRIPV
FYGHSESISMETEKEISPEEAREVLKNAPGVIVIDNPQNNEYPMPIMAEGRDEVFVGRIRKDRVFEPGLSMWVVADNIRK
GAATNAVQIAELLVKEGLI

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1788658, Length=339, Percent_Identity=36.8731563421829, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789841, Length=356, Percent_Identity=26.685393258427, Blast_Score=110, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320362, Length=398, Percent_Identity=30.6532663316583, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DHAS_AQUAE (O67716)

Other databases:

- EMBL:   AE000657
- PIR:   B70461
- RefSeq:   NP_214284.1
- ProteinModelPortal:   O67716
- SMR:   O67716
- GeneID:   1193523
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1866
- NMPDR:   fig|224324.1.peg.1299
- HOGENOM:   HBG518238
- OMA:   DNSSTWR
- PhylomeDB:   O67716
- ProtClustDB:   CLSK2299852
- BioCyc:   AAEO224324:AQ_1866-MONOMER
- BRENDA:   1.2.1.11
- GO:   GO:0005737
- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF000148
- SMART:   SM00859
- TIGRFAMs:   TIGR01296

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.11

Molecular weight: Translated: 37800; Mature: 37669

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS01103 ASD

Important sites: ACT_SITE 131-131

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYRVAIVGATGEVGRTFLKVLEERNFPVDELVLYASERSEGKVLTFKGKEYTVKALNKE
CCEEEEEEECCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCEEEEECCEEEEEEECCC
NSFKGIDIALFSAGGSTSKEWAPKFAKDGVVVIDNSSAWRMDPDVPLVVPEVNPEDVKDF
CCCCCEEEEEEECCCCCCHHHCCHHHCCCEEEEECCCCEEECCCCCEEECCCCHHHHHHH
KKKGIIANPNCSTIQMVVALKPIYDKAGIKRVVVSTYQAVSGAGAKAIEDLKNQTKAWCE
HHCCCEECCCCCEEEEEEEEECHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
GKEMPKAQKFPHQIAFNALPHIDVFFEDGYTKEENKMLYETRKIMHDENIKVSATCVRIP
CCCCCCHHHCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEE
VFYGHSESISMETEKEISPEEAREVLKNAPGVIVIDNPQNNEYPMPIMAEGRDEVFVGRI
EEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCEEEEEC
RKDRVFEPGLSMWVVADNIRKGAATNAVQIAELLVKEGLI
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GYRVAIVGATGEVGRTFLKVLEERNFPVDELVLYASERSEGKVLTFKGKEYTVKALNKE
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCEEEEECCEEEEEEECCC
NSFKGIDIALFSAGGSTSKEWAPKFAKDGVVVIDNSSAWRMDPDVPLVVPEVNPEDVKDF
CCCCCEEEEEEECCCCCCHHHCCHHHCCCEEEEECCCCEEECCCCCEEECCCCHHHHHHH
KKKGIIANPNCSTIQMVVALKPIYDKAGIKRVVVSTYQAVSGAGAKAIEDLKNQTKAWCE
HHCCCEECCCCCEEEEEEEEECHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
GKEMPKAQKFPHQIAFNALPHIDVFFEDGYTKEENKMLYETRKIMHDENIKVSATCVRIP
CCCCCCHHHCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEE
VFYGHSESISMETEKEISPEEAREVLKNAPGVIVIDNPQNNEYPMPIMAEGRDEVFVGRI
EEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCEEEEEC
RKDRVFEPGLSMWVVADNIRKGAATNAVQIAELLVKEGLI
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320