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The map label for this gene is fumX [C]

Identifier: 15606776

GI number: 15606776

Start: 1179364

End: 1179921

Strand: Direct

Name: fumX [C]

Synonym: aq_1679

Alternate gene names: 15606776

Gene position: 1179364-1179921 (Clockwise)

Preceding gene: 15606775

Following gene: 15606777

Centisome position: 76.02

GC content: 47.67

Gene sequence:

>558_bases
ATGGAGAAGAGAATTACGACACCTCTTACGGACGAAGTTGTGAAGTCCTTAAGGGCGGGAGACAAGGTTCTCATAACGGG
CTACATTTATACCGCAAGGGACGCAGCCCACAAGAGAATGGTTGAAGCTATACAGAGGGGAGAAAAACCGCCGATAGACT
TAAAAGGTCAAATAATCTACTACGTAGGCCCAACTCCACCAAAGCCCGGACAGGTTATAGGCTCTGCCGGACCTACCACA
GCGATAAGAATGGACAAGTACGTGGAACCCCTCCTAAAGCTCGGACTGAAGGGAATGATAGGAAAAGGTTACAGAAGCCC
GCAAGTTAAAGAACTGCTGAAAAAGTACAAGGCTGTTTACTTTGCGGCGGTTGGAGGAGTAGCGACCCTTCTCCAGAAGC
ACATAAAGAGTTCCGAGCTTATAGCTTATGAGGACTTAGGAACGGAAGCCATAAGAAGACTTTACGTTGAGGATTTTCCC
GTTATCGTTGCAAACGACGCCTTCGGAGGCGACGTATTCGAAGAGGGCAGGAAGAAGTACGCGAAAATAGATGTTTAA

Upstream 100 bases:

>100_bases
CCGAAGACTCAAAGAGGTATATGTCCTCTTACGGGAGCGCCCGATTACGTGGACCCCAAACAACTCAAGGAACTTCACAT
AAAAGTTTTAGAATAAAAGT

Downstream 100 bases:

>100_bases
AAGGATAAGGGAAATAAAGGAAAAGGAACAGGAAGAATTAGTAAGGAAAATATCGGAACTACTAGCGCTCGAAAGAGAAC
TCGAAAGGAAACTTGAAGAA

Product: C-terminal fumarate hydratase, class I

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MEKRITTPLTDEVVKSLRAGDKVLITGYIYTARDAAHKRMVEAIQRGEKPPIDLKGQIIYYVGPTPPKPGQVIGSAGPTT
AIRMDKYVEPLLKLGLKGMIGKGYRSPQVKELLKKYKAVYFAAVGGVATLLQKHIKSSELIAYEDLGTEAIRRLYVEDFP
VIVANDAFGGDVFEEGRKKYAKIDV

Sequences:

>Translated_185_residues
MEKRITTPLTDEVVKSLRAGDKVLITGYIYTARDAAHKRMVEAIQRGEKPPIDLKGQIIYYVGPTPPKPGQVIGSAGPTT
AIRMDKYVEPLLKLGLKGMIGKGYRSPQVKELLKKYKAVYFAAVGGVATLLQKHIKSSELIAYEDLGTEAIRRLYVEDFP
VIVANDAFGGDVFEEGRKKYAKIDV
>Mature_185_residues
MEKRITTPLTDEVVKSLRAGDKVLITGYIYTARDAAHKRMVEAIQRGEKPPIDLKGQIIYYVGPTPPKPGQVIGSAGPTT
AIRMDKYVEPLLKLGLKGMIGKGYRSPQVKELLKKYKAVYFAAVGGVATLLQKHIKSSELIAYEDLGTEAIRRLYVEDFP
VIVANDAFGGDVFEEGRKKYAKIDV

Specific function: It Functions As An Aerobic Enzyme In The Citric Acid Cycle. It Accounts For About 80% Of The Fumarase Activity When The Bacteria Grows Aerobically. [C]

COG id: COG1838

COG function: function code C; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1787897, Length=156, Percent_Identity=41.6666666666667, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1790564, Length=156, Percent_Identity=41.6666666666667, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789443, Length=188, Percent_Identity=32.4468085106383, Blast_Score=103, Evalue=7e-24,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004647 [H]

Pfam domain/function: PF05683 Fumerase_C [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 20441; Mature: 20441

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRITTPLTDEVVKSLRAGDKVLITGYIYTARDAAHKRMVEAIQRGEKPPIDLKGQIIY
CCCCCCCCHHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
YVGPTPPKPGQVIGSAGPTTAIRMDKYVEPLLKLGLKGMIGKGYRSPQVKELLKKYKAVY
EECCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHH
FAAVGGVATLLQKHIKSSELIAYEDLGTEAIRRLYVEDFPVIVANDAFGGDVFEEGRKKY
HHHHHHHHHHHHHHCCCCCEEEHHHCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHH
AKIDV
HCCCC
>Mature Secondary Structure
MEKRITTPLTDEVVKSLRAGDKVLITGYIYTARDAAHKRMVEAIQRGEKPPIDLKGQIIY
CCCCCCCCHHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
YVGPTPPKPGQVIGSAGPTTAIRMDKYVEPLLKLGLKGMIGKGYRSPQVKELLKKYKAVY
EECCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHH
FAAVGGVATLLQKHIKSSELIAYEDLGTEAIRRLYVEDFPVIVANDAFGGDVFEEGRKKY
HHHHHHHHHHHHHHCCCCCEEEHHHCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHH
AKIDV
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]