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The map label for this gene is iagB [H]

Identifier: 15606704

GI number: 15606704

Start: 1114896

End: 1115450

Strand: Direct

Name: iagB [H]

Synonym: aq_1579

Alternate gene names: 15606704

Gene position: 1114896-1115450 (Clockwise)

Preceding gene: 15606703

Following gene: 15606705

Centisome position: 71.87

GC content: 41.98

Gene sequence:

>555_bases
TTGATGAGGATACAAAACTTTTTCTCTCCCAACATTCCCCTGAAAACCACGAGGAAAGAGCACATAAGGGGGGATTTTTA
CTCGGAACTTAAAAGCTTTAAGCCCGTAATTGAAAGAAATACAATATCCTTGCAAAATCCCTACTCCTCTCCAATAAAAT
CTCAGATAAACAAGGAGTATATAAAGGAACTTGCGAGAAAGAAGGCGCAGAAATACGGCGTCCCCCTAAATATAGTCCTC
GCAATTATAGAAAAGGAAAGCTCTTTTAACCCTAAGGCTTACAACAAAAACAAGGACGGGACAGAAGACGTAGGCCTAAT
GCAGATAAACTTCCAGCACAACAAAAGACTCATGAGGGAGTACGGCGTAAACTCACCCGAGGAGCTTTACGACCCGGAAC
TGAACCTTGAACTCGGTGTGAGAATACTTTACGAAAACTACAAAAGGTACGGTTCGTGGGAGCTTGCCGTAAAGGCTTAC
AACGGGATAAGGGCGGATAACTGGGATTACGTAAAAAATGTTATGGAAAGGGCTAAAAAGTACGTAAACTTATAG

Upstream 100 bases:

>100_bases
CCCACGTTTGCCCCCACGGAAGACCCATATACTACAAAATACCCCTGAGGGAAATATACGAAAAAGTAGGCAGGAATTAC
TGAAGGTGGTAAATTAATCC

Downstream 100 bases:

>100_bases
AAATGGCAAGAATTTGTGTTGCTCTGGACGTCCCCTGGGAAAGGGCTATAAAGATAGTAAAAGACCTTTACGACTTCTTT
GAAACATATCCCCTTATCTT

Product: invasion protein IagB

Products: N-Acetylmuramic Acid Residues; N-Acetylglucosamine Residues [C]

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MMRIQNFFSPNIPLKTTRKEHIRGDFYSELKSFKPVIERNTISLQNPYSSPIKSQINKEYIKELARKKAQKYGVPLNIVL
AIIEKESSFNPKAYNKNKDGTEDVGLMQINFQHNKRLMREYGVNSPEELYDPELNLELGVRILYENYKRYGSWELAVKAY
NGIRADNWDYVKNVMERAKKYVNL

Sequences:

>Translated_184_residues
MMRIQNFFSPNIPLKTTRKEHIRGDFYSELKSFKPVIERNTISLQNPYSSPIKSQINKEYIKELARKKAQKYGVPLNIVL
AIIEKESSFNPKAYNKNKDGTEDVGLMQINFQHNKRLMREYGVNSPEELYDPELNLELGVRILYENYKRYGSWELAVKAY
NGIRADNWDYVKNVMERAKKYVNL
>Mature_184_residues
MMRIQNFFSPNIPLKTTRKEHIRGDFYSELKSFKPVIERNTISLQNPYSSPIKSQINKEYIKELARKKAQKYGVPLNIVL
AIIEKESSFNPKAYNKNKDGTEDVGLMQINFQHNKRLMREYGVNSPEELYDPELNLELGVRILYENYKRYGSWELAVKAY
NGIRADNWDYVKNVMERAKKYVNL

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division (By Similarity). [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iagB/ipgF/P19 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 21720; Mature: 21720

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRIQNFFSPNIPLKTTRKEHIRGDFYSELKSFKPVIERNTISLQNPYSSPIKSQINKEY
CCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
IKELARKKAQKYGVPLNIVLAIIEKESSFNPKAYNKNKDGTEDVGLMQINFQHNKRLMRE
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHH
YGVNSPEELYDPELNLELGVRILYENYKRYGSWELAVKAYNGIRADNWDYVKNVMERAKK
HCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
YVNL
HCCC
>Mature Secondary Structure
MMRIQNFFSPNIPLKTTRKEHIRGDFYSELKSFKPVIERNTISLQNPYSSPIKSQINKEY
CCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
IKELARKKAQKYGVPLNIVLAIIEKESSFNPKAYNKNKDGTEDVGLMQINFQHNKRLMRE
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHH
YGVNSPEELYDPELNLELGVRILYENYKRYGSWELAVKAYNGIRADNWDYVKNVMERAKK
HCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
YVNL
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7754225; 11677608; 12644504 [H]