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The map label for this gene is apbE [H]

Identifier: 15606483

GI number: 15606483

Start: 888261

End: 889127

Strand: Direct

Name: apbE [H]

Synonym: aq_1258

Alternate gene names: 15606483

Gene position: 888261-889127 (Clockwise)

Preceding gene: 15606482

Following gene: 15606484

Centisome position: 57.26

GC content: 38.75

Gene sequence:

>867_bases
TTGATACTAATACTCCTTTTCCTCCTCATAAACTTCCTCTTTGCGGAAAGAGTTTTTTACCTTATGGGAACTTATCTGAT
TCTGGACGAACTCCGCGGAAAAGAAGTAGCAGTTTACAAATACATGAAAAAGCTGGAAGAGAAGCTCTCTCACTTTATAC
CGGACTCTGAAATTTCCCGAATAAACGAGAACGCTGGAATAAAACCCGTAAAAGTTTCCAAAGAAACTTATGAAATTCTG
AAAATATCTAAGGAAATAGCAGAAAAAACTTACGGATACTTTGACCCAACCGTAGGAAGTTACACGGTAAACTTTAAAAT
GAAAAAATTAATTTCCGAGAAAAAAGCGAAATCCTTAATAAATTTCAAAGATTTAATACTCTTTCCTGAAGAAAGAAAAG
TTTTTTTAAGGAAAAAGTATATGGCTCTTGACCTCGGCGGTATAGGTAAAGGTTTTGCAGTTCAGAAGGCTTACGAATAC
ATAAAAACGGAGAAGGGATTTATAGCCCTTGCGGGCGATATGAAAGTTTGGGGACACAAAAGAAAACTCGCGGTTTACAA
TCCGATAAACGGAAAAATCCTCGCGGAAGGTGTAAACAAAAAAGATTTGTGTCTCTCTACCTCTGGAAATTACTTCAGGA
AACACATCTTGGGAAAAAGTAAAAGAGTATTACAGATTACGGTGGCTCACGAGAACTGCACCGTAGCGGACGCTCTCGCA
ACCGCCCTCTTCGCCTCTCCAGAAAAGGAAAGAGAGAAAATTCTGAAAAACTTTCCAGAAGCCGCTGTTCTCATTCTCTA
CACAGACGGAAGCCTGTTTGTGAATGGAAAATTTAGGGACTTCTTCGAGTACTTAATCCTGTACTGA

Upstream 100 bases:

>100_bases
AGATGCTCGGGGAAAAGGAATTCCTGAAAGAGTTAAAACCTTACTCTAAGAACACTTACAAACTCGGCGAAAGAAAAATA
CTATTTCCCAAAAGGGAAGG

Downstream 100 bases:

>100_bases
AATGACTTCAGTCATAGAAGTAAGTTTTTTTCTTTTGTTAATATACTGAAATCAAATTTCAATTTTAAGGAGGTGTGTGA
TGAAAAGATTTGTGGCGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MILILLFLLINFLFAERVFYLMGTYLILDELRGKEVAVYKYMKKLEEKLSHFIPDSEISRINENAGIKPVKVSKETYEIL
KISKEIAEKTYGYFDPTVGSYTVNFKMKKLISEKKAKSLINFKDLILFPEERKVFLRKKYMALDLGGIGKGFAVQKAYEY
IKTEKGFIALAGDMKVWGHKRKLAVYNPINGKILAEGVNKKDLCLSTSGNYFRKHILGKSKRVLQITVAHENCTVADALA
TALFASPEKEREKILKNFPEAAVLILYTDGSLFVNGKFRDFFEYLILY

Sequences:

>Translated_288_residues
MILILLFLLINFLFAERVFYLMGTYLILDELRGKEVAVYKYMKKLEEKLSHFIPDSEISRINENAGIKPVKVSKETYEIL
KISKEIAEKTYGYFDPTVGSYTVNFKMKKLISEKKAKSLINFKDLILFPEERKVFLRKKYMALDLGGIGKGFAVQKAYEY
IKTEKGFIALAGDMKVWGHKRKLAVYNPINGKILAEGVNKKDLCLSTSGNYFRKHILGKSKRVLQITVAHENCTVADALA
TALFASPEKEREKILKNFPEAAVLILYTDGSLFVNGKFRDFFEYLILY
>Mature_288_residues
MILILLFLLINFLFAERVFYLMGTYLILDELRGKEVAVYKYMKKLEEKLSHFIPDSEISRINENAGIKPVKVSKETYEIL
KISKEIAEKTYGYFDPTVGSYTVNFKMKKLISEKKAKSLINFKDLILFPEERKVFLRKKYMALDLGGIGKGFAVQKAYEY
IKTEKGFIALAGDMKVWGHKRKLAVYNPINGKILAEGVNKKDLCLSTSGNYFRKHILGKSKRVLQITVAHENCTVADALA
TALFASPEKEREKILKNFPEAAVLILYTDGSLFVNGKFRDFFEYLILY

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 33067; Mature: 33067

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILILLFLLINFLFAERVFYLMGTYLILDELRGKEVAVYKYMKKLEEKLSHFIPDSEISR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
INENAGIKPVKVSKETYEILKISKEIAEKTYGYFDPTVGSYTVNFKMKKLISEKKAKSLI
HCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHC
NFKDLILFPEERKVFLRKKYMALDLGGIGKGFAVQKAYEYIKTEKGFIALAGDMKVWGHK
CHHHEEEECHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCEEECCCC
RKLAVYNPINGKILAEGVNKKDLCLSTSGNYFRKHILGKSKRVLQITVAHENCTVADALA
CEEEEECCCCCEEEECCCCCCCEEEECCCHHHHHHHCCCCCEEEEEEEECCCCCHHHHHH
TALFASPEKEREKILKNFPEAAVLILYTDGSLFVNGKFRDFFEYLILY
HHHHCCCHHHHHHHHHCCCCEEEEEEEECCCEEECCCHHHHHHHHHCC
>Mature Secondary Structure
MILILLFLLINFLFAERVFYLMGTYLILDELRGKEVAVYKYMKKLEEKLSHFIPDSEISR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
INENAGIKPVKVSKETYEILKISKEIAEKTYGYFDPTVGSYTVNFKMKKLISEKKAKSLI
HCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHC
NFKDLILFPEERKVFLRKKYMALDLGGIGKGFAVQKAYEYIKTEKGFIALAGDMKVWGHK
CHHHEEEECHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCEEECCCC
RKLAVYNPINGKILAEGVNKKDLCLSTSGNYFRKHILGKSKRVLQITVAHENCTVADALA
CEEEEECCCCCEEEECCCCCCCEEEECCCHHHHHHHCCCCCEEEEEEEECCCCCHHHHHH
TALFASPEKEREKILKNFPEAAVLILYTDGSLFVNGKFRDFFEYLILY
HHHHCCCHHHHHHHHHCCCCEEEEEEEECCCEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]